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001-es BibID:BIBFORM034875
Első szerző:Ebel, H.
Cím:Effects of Electrical Stimulation of theGasserian Ganglion on Regional Cerebral Blood Flow after Induced Subarachnoid Hemorrhage in Pigs Evaluated by 99mTc-HMPAO-SPECT / Ebel H., Semmelmann G., Friese M., Volz M., Lee J. Y., Dück M., Schomäcker K., Varga J., Furka I., Schröder R., Klug N.
Dátum:2001
ISSN:0946-7211
Megjegyzések:It could be demonstrated that cervical spinal cord stimulation increases cerebral blood flow. The effects of electrical stimulation of the trigeminal ganglion in the acute phase of SAH in pigs were investigated. The experiments were carried out on 11 domestic pigs divided in two groups (group I: SAH [n = 5]; group II: SAH and trigeminal stimulation [n = 6]). In all animals a native SPECT was performed. The Gasserian ganglion was exposed for inserting the stimulation electrode. SAH was induced by injecting 10 ml autologous blood through a catheter placed in the suprasellar cistern. 30 minutes after SAH-induction electrical stimulation was started for two hours in group II (2.8-4.5 V, 50 Hz, 300 microseconds). 99mTc-HMPAO (400-540 MBq) was injected intravenously 110 minutes later. In group I 99mTc-HMPAO was applied after the same time interval. 80 minutes later SPECT was performed. Data were processed to calculate the uptake of radioactivity (%/kg tissue weight). The mean values were calculated for the different groups: native animal examination (%/kg tissue weight): 0.6343; group I: 0.468; group II: 0.6533. Comparing the mean values a highly significant difference between group I and group II (p < 0.01) and between native examination and group I (p < 0.01) could be found. No statistical significance could be detected on comparing the left/right-ratio in any ROI. The electrical stimulation of the Gasserian ganglion leads to a significantly increased uptake of 99mTc-HMPAO after induced SAH. Maybe the stimulation of the Gasserian ganglion constitutes a new therapeutic modality treating disturbed rCBF after SAH.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Minimally Invasive Neurosurgery. - 44 : 1 (2001), p. 50-57. -
További szerzők:Semmelmann G. Friese, M. Volz, M. Lee, J. Y. Dück, M. Schomäcker, K. Varga József (1955-) (fizikus) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Schröder, Roland Klug, Norfrid
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001-es BibID:bibEBI16681
Első szerző:Rieger, Andreas
Cím:Continuous monitoring of oxygen partial pressure in cerebral venous blood / Rieger, A., Menzel, M., Rainov, N., Sanchin, L., Roth, S., Görömbey, Z., Furka, I., Burkert, W.
Dátum:1997
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Neurosurgery. - 41 (1997), p. 462-467. -
További szerzők:Menzel, Matthias (sebész) Rainov, Nicolai Sanchin, Lhagva Roth, Stephan Görömbey Zoltán (1956-) (idegsebész) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Burkert, Winfried
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