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001-es BibID:BIBFORM072240
Első szerző:Csorba Roland (szülész-nőgyógyász, gyermeknőgyógyász)
Cím:Correlation of rheological parameters in maternal and fetal blood at term / Csorba Roland, Soliman Amr A., Wieg Christian, Tsikouras Panagiotis, Rath Werner, von Tempelhoff Georg-Friedrich
Dátum:2014
ISSN:1476-7058 1476-4954
Megjegyzések:Objective: An association between maternal and fetal blood rheology has not yet been investigated nor is it known whether and to what extent fetal blood rheology may be affected by maternal conditions. Methods: At delivery, blood was drawn from the cubital vein of 4985 consecutive mothers and from the umbilical cord during birth for determination of blood rheological parameters (erythrocyte aggregation stasis [E0], low shear [E1], plasma viscosity [Pv]) in addition to hemoglobin (Hb) values and hematocrit (Hct). Results: Maternal and newborn Pv (r = 0.2; p < 0.0001) correlated statistically significant. There was a remarkable correlation between fetal Pv and gestational age (r = 0.197; p < 0.001). Iron supplementation during pregnancy led to increased fetal Hb, Hct as well as E0 and E1 (p < 0.0001), did not have a significant impact on neonatal Pv (p = 0.068). Smoking mothers gave birth to neonates with significantly higher Pv (p = 0.049), E0 (p = 0.016) and E1 (p = 0.013). Conclusions: The increase of fetal plasma viscosity at advanced delivery time-points refers to a more gaining protein synthesis by the fetal liver and thus maturity of the fetus. Iron supplementation as well as smoking during pregnancy is associated with a relative hyper-viscosity in the fetus at delivery.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Fetal maturity
Plasma viscosity
Pregnancy
Red blood cell aggregation
Rheology
Megjelenés:The Journal of Maternal-Fetal & Neonatal Medicine 28 : 8 (2014), p. 969-976. -
További szerzők:Soliman, Amr A. Wieg, Christian Tsikouras, Panagioti Rath, Werner Tempelhoff, Georg-Friedrich von
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DOI
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2.

001-es BibID:bibEBI00019042
Első szerző:Gyámfi Cynthia
Cím:Single-versus double-layer uterine incision closure and uterine rupture / Gyámfi C., Juhász A. G., Gyámfi P., Blumenfeld Y., Stone J. L.
Dátum:2006
Megjegyzések:To evaluate whether closure of the uterine incision with one or two layers changes uterine rupture or vaginal birth after cesarean section (VBAC) success rates. METHODS: Subjects with one previous cesarean section by documented transverse uterine incision that attempted VBAC were identified. Exclusion criteria included lack of documentation of the type of closure of the previous uterine incision, multiple gestation, more than one previous cesarean section, and previous scar other than low transverse. Uterine rupture and VBAC success rates were compared between those with single-layer and double-layer uterine closure. Time interval between deliveries, birth weight, body mass index (BMI), and history of previous VBAC were evaluated as possible confounders. RESULTS: Of 948 subjects identified, 913 had double-layer closure and 35 had single-layer closure. The uterine rupture rate was significantly higher in the single-layer closure group (8.6% vs. 1.3%, p = 0.015). This finding persisted when controlling for previous VBAC, induction, birth weight >4000 g, delivery interval >19 months, and BMI >29 (OR 8.01, 95% CI 1.96-32.79). There was no difference in VBAC success rate (74.3% vs. 77%, p = 0.685). CONCLUSION: Single-layer uterine closure may be more likely to result in uterine rupture.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:The Journal of Maternal-Fetal and Neonatal Medicine. - 19 : 10 (2006), p. 639-643. -
További szerzők:Juhász Alpár Gábor (1973-) (szülész-nőgyógyász, gyermeknőgyógyász) Gyámfi Phyllis Blumenfeld, Yair Stone, Joanne L.
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3.

001-es BibID:BIBFORM034305
Első szerző:Papp Csaba (szülész-nőgyógyász)
Cím:Risk of recurrence of craniospinal anomalies / Papp Csaba, Adám Zsolt, Tóth-Pál Ernő, Török Olga, Váradi Valéria, Papp Zoltán
Dátum:1997
Megjegyzések:The authors analyzed 1,655 situations from their Genetic Counseling Service over a 15 year period where the reason for counseling was craniospinal anomaly (neural tube defects and/or hydrocephalus) in the family. Excluding the obviously monogenically inherited cases, they investigated pregnancies undertaken after 1,285 isolated and 177 multiple forms of craniospinal abnormalities. The recurrence rate of craniospinal defects was found to be 3.66%, which is about ten times higher than the general population risk, supporting the theory of the multifactorial threshold model in the inheritance of these anomalies. The recurrence risks of neural tube defects and of hydrocephalus were 3.47% and 2.95%, respectively. The authors concluded that recurrence risk is mainly influenced by the pathoanatomic severity of the involved anomaly, the degree of relationship, and the number of affected relatives in the family. There is a positive correlation between the pathoanatomic severity of the anomaly in the proband and the offspring. At least in one-half of the cases the same type of anomaly was observed again in the offspring as in the proband. Attention is drawn to the fact that hydrocephalus (ventriculomegaly) is often manifested only in the second half of gestation. Therefore, performing ultrasound examination is strongly recommended not only at the 18th but at the 24th week of gestation, as well in pregnancies with a positive history of neural tube defects and/or hydrocephalus.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:The Journal of Maternal-Fetal Medicine. - 6 : 1 (1997), p. 53-57. -
További szerzők:Ádám Zsolt Tóth-Pál Ernő (nőgyógyász) Török Olga (1956-) (szülész-nőgyógyász, humángenetikus) Váradi Valéria Papp Zoltán (1942-) (szülész-nőgyógyász, genetikus)
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