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001-es BibID:	BIBFORM115729
035-os BibID:	(cikkazonosító)11733
Első szerző:	Muthu Arjun (Ph.D. student)
Cím:	Microbial-Based Biotechnology: Production and Evaluation of Selenium-Tellurium Nanoalloys / Arjun Muthu, Daniella Sári, Aya Ferroudj, Hassan El-Ramady, Áron Béni, Khandsuren Badgar, József Prokisch
Dátum:	2023
ISSN:	2076-3417
Megjegyzések:	Using seleno-compounds and telluric compounds is a practical approach for developing solutions against drug-resistant bacterial infections and malignancies. It will accelerate the search for novel treatments or adjuvants for existing therapies. Selenium and tellurium nanospheres can be produced by lactic acid bacteria. The bacteria can differentiate the selenium and tellurium when the medium contains both selenite and tellurite. Therefore, our question in this study was the following: are they making alloys from the selenium and tellurium and what will be the composition, color, and shape of the nanoparticles? We used a simple microbial synthesis to produce nanoselenium, nanotellurium, and their alloys from sodium selenite and sodium tellurite using Lactobacillus casei. This bacterium produced red spherical amorphous elemental selenium nanospheres with a diameter of 206 ? 33 nm from selenite and amorphous black nanorods with a length of 176 ? 32 nm and a cross-section of 62 ? 13 nm from tellurite. If the initial medium contains a mixture of selenite and tellurite, the resulting nanoparticles will contain selenium and tellurium in the same ratios in the alloy as in the medium. This proves that Lactobacillus casei cannot distinguish between selenite and tellurite. The shape of the nanoparticles varies from spherical to rod-shaped, depending on the ratio of selenium and tellurium. The color of nanomaterials ranges from red to black, depending on the percentage of selenium and tellurium. These nanomaterials could be good candidates in the pharmaceutical industry due to their antipathogenic and anticarcinogenic properties.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk green synthesis Lactobacillus casei nanoalloys selenium tellurium
Megjelenés:	Applied Sciences-Basel. - 13 : 21 (2023), p.1-14. -
További szerzők:	Sári Daniella (1991-) (dietetikus, élelmiszer mérnök, mezőgazdasági mérnök) Ferroudj, Aya El-Ramady, Hassan (1969-) (agrármérnök) Béni Áron (1978-) (vegyész) Badgar, Khandsuren (1987-) (állattenyésztés) Prokisch József (1966-) (vegyész)
Pályázati támogatás:	Stipendium Hungaricum Scholarship Program Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM101006
035-os BibID:	(cikkazonosító)4220 (Scopus)85106190883 (WOS)000649894100001
Első szerző:	Vicas Simona
Cím:	Functional Food Product Based on Nanoselenium-Enriched Lactobacillus casei against Cadmium Kidney Toxicity / Simona Ioana Vicas, Vasile Laslo Adrian Vasile Timar, Cornel Balta, Hildegard Herman, Alina Ciceu, Sami Gharbia, Marcel Rosu, Bianca Mladin, Luminita Fritea, Simona Cavalu, Coralia Cotoraci, József Prokisch, Maria Puschita, Calin Pop, Eftimie Miutescu, Anca Hermenean
Dátum:	2021
ISSN:	2076-3417
Megjegyzések:	This paper demonstrates the ability of a functional food based on probiotics and selenium nanoparticles (SeNPs) to annihilate the toxic effect of cadmium on the kidneys. SeNPs were obtained by eco-friendly method used Lactobacillus casei. The morphological features and size of SeNPS were characterized by Atomic Force Microscopy (AFM) and Dynamic Light Scattering (DLS). Two kind of SeNPs were used, purified and Lacto-SeNPs (LSeNPs), administered by gavage at three concentrations (0.1, 0.2, and 0.4 mg/Kg b.w.) for 30 days in a mouse model of cadmium renal toxicity. The blood marker of renal injury (creatinine) significantly decreased in groups where the mice were treated with both form of SeNPs. The antioxidant capacity of plasma was evaluated by Trolox Equivalent Antioxidant Capacity (TEAC) assay and revealed that SeNPs in co-treatment with Cd, promotes maintaining antioxidant activity at the control level. Histopathological analysis of kidneys demonstrated morphological alteration in the group that received only cadmium and restored after administration of SeNPs or LSeNPs. In addition, immunohistochemical analysis revealed anti-apoptotic effects through reduction of pro-apoptotic bax and increasing of anti-apoptotic Bcl-2 protein expressions. Moreover, co-administration of Cd with SeNPs significantly decreased gene expression of kidneys inflammatory markers (TNF-alpha, IL-6, NF-B) in a dose dependent manner, with the best results for LSeNPs at highest dose (0.4 mg/kg). Therefore, the L. casei strain is a potential SeNPs-enriched probiotic for application as functional food in the future to annihilate cadmium-induced kidneys toxicity.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk cadmium selenium Lactobacillus casei kidneys histology apoptosis inflammation functional food probiotics
Megjelenés:	Applied Sciences-Basel. - 11 : 9 (2021), p. 1-15. -
További szerzők:	Laslo, Vasile Timar, Adrian Vasile Balta, Cornel Herman, Hildegard Ciceu, Alina Gharbia, Sami Rosu, Marcel Mladin, Bianca Fritea, Luminita Cavalu, Simona Cotoraci, Coralia Prokisch József (1966-) (vegyész) Puschita, Maria Pop, Calin Miutescu, Eftimie Hermenean, Anca
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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