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001-es BibID:BIBFORM081137
035-os BibID:(PMID)31313247
Első szerző:Barna Sándor (kutató orvos)
Cím:Clinical utility of SPECT/CT and CT-dacryocystography-enhanced dacryoscintigraphy in the imaging of lacrimal drainage system obstruction / Sandor Barna, Ildiko Garai, Kornel Kukuts, Rudolf Gesztelyi, Laszlo Toth, Adam Kemeny-Beke
Dátum:2019
ISSN:0914-7187 1864-6433
Megjegyzések:Purpose Epiphora is commonly caused by a relative or complete occlusion in the lacrimal drainage system (LDS), principally a nasolacrimal duct obstruction (NLDO). Dacryoscintigraphy (DSG), an extensively assessed imaging technique in diagnosing its abnormalities, can provide only planar images, according to which it needs to be improved. Our aim was to evaluate clinical utility of simultaneous DSG and single-photon emission computed tomography/computed tomography (SPECT/CT) combined with computed tomographic dacryocystography (CT-DCG) in the evaluation of LDS. Methods Dynamic imaging with DSG was performed, and tracer radioactivity was detected by a gamma camera. Successively, SPECT/CT images of the involved region were gained, followed by CT-DCG, during which a contrast medium was syringed into the affected LDS, and finally contrast CT scans were obtained again from the same region. Results Fifty-seven patients, mean age 54.25 (? 18.26) years all with unilateral NLDO and 32 control subjects, all with patent LDS, mean age 49.88 (? 18.61) years were evaluated in the study. Delayed outflow of tearing eyes was exposed to DSG compared to the fellow and control eyes. The highest value for sensitivity was observed for SPECT/CT, followed by CT-DCG and DSG techniques, while combining DSG with SPECT/CT, DSG with CT-DCG, and SPECT/CT with CT-DCG, the sensitivity increased to 96.49%, 92.98%, and 94.73%, respectively. Conclusions Although DSG is a sensitive nuclear medicine method, it only provides useful clinical data when simultaneously supplemented with SPECT/CT and CT-DCG trials as they jointly can offer valuable information about the localization of an abnormality and verify stenosis or obstruction.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
dacryoscintigraphy
SPECT/CT
epiphora
Megjelenés:Annals of Nuclear Medicine. - 33 : 10 (2019), p. 746-754. -
További szerzők:Garai Ildikó (1966-) (radiológus) Kukuts Kornél Gesztelyi Rudolf (1969-) (kísérletes farmakológus) Tóth László (1957-) (fül-orr-gégész) Kemény-Beke Ádám (1968-2021) (szemész)
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2.

001-es BibID:BIBFORM102720
035-os BibID:(WOS)000817858700001 (Scopus)85133079103
Első szerző:Farkas Bence
Cím:Unusual perfusion patterns on perfusion-only SPECT/CT scans in COVID-19 patients / Farkas Bence, Képes Zita, Barna Sándor Kristóf, Szugyiczki Viktória, Bakos Magdolna, Forgács Attila, Garai Ildikó
Dátum:2022
ISSN:0914-7187 1864-6433
Megjegyzések:Purpose We aimed at examining both the incidence and extent of different lung perfusion abnormalities as well as the relationship between them on Tc-99m macroaggregated albumin (MAA) perfusion-only SPECT/CT scans in COVID-19 patients. Methods Ninety-one patients (71.4???13.9 years; range: 29?98 years, median age: 74 years; 45 female and 46 male) with confirmed SARS-CoV-2 virus infection were included in this retrospective study. After performing perfusion-only Tc-99m MAA SPECT/CT scans, visual, semi-quantitative assessment of the subsequent perfusion abnormalities was carried out: mismatch lesions (MM; activity defects on SPECT images identical to apparently healthy parenchyma on CT images), matched lesions (MA; activity defects with corresponding parenchymal lesions on CT scans), and reverse mismatch lesions (RM; parenchymal lesions with preserved or increased tracer uptake). Lesion-based and patient-based analysis were performed to evaluate the extent, severity, and incidence of each perfusion abnormality. Statistical tests were applied to investigate the association between the experienced perfusion impairments. Results Moderately severe parenchymal lesions were detected in 87 (95.6%) patients. Although, 50 (54.95%) patients were depicted to have MM lesions, the whole patient cohort was mildly affected by this abnormality. MA lesions of average moderate severity were seen in most of the patients (89.01%). In 65 (71.43%) patients RM lesions were found with mild severity on average. Positive association was detected between total CT score and total RM score and between total CT score and total MA score. Significantly higher total CT scores were experienced in the subgroup, where RM lesions were present. Conclusions Heterogeneous perfusion abnormalities were found in most of COVID-19 patients: parenchymal lesions with normal, decreased or increased perfusion and perfusion defects in healthy lung areas. These phenomena may be explained by the failure of the hypoxic pulmonary vasoconstriction mechanism and presence of pulmonary thrombosis and embolism.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Annals Of Nuclear Medicine. - 36 : 9 (2022), p. 804-811. -
További szerzők:Képes Zita (1991-) (orvos) Barna Sándor (1982-) (kutató orvos) Szugyiczki Viktória Bakos Magdolna Forgács Attila (1985-) (fizikus) Garai Ildikó (1966-) (radiológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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