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001-es BibID:	BIBFORM006471
Első szerző:	Miskei Márton (molekuláris biológus, genetikus)
Cím:	Annotation of stress-response proteins in the aspergilli / Márton Miskei, Zsolt Karányi, István Pócsi
Dátum:	2009
Megjegyzések:	Stress-response proteins of Aspergillus nidulans, Aspergillus clavatus, Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus oryzae, Aspergillus terreus and Neosartorya fischeri (3908 in total) were annotated and grouped according to stress types (http://193.6.155.82/AspergillusStress/). All genomes harboured elements of the SskA-HogA/SakA stress signalling pathway. There are accumulating data pointing at the importance of SskA-HogA/SakA signalling in different types of stress-responses in the aspergilli and, in this regard, these filamentous fungi are closer to fission yeast than to budding yeast. The abundance of annotated stress sensing histidine kinases and transcriptional regulators in each Aspergillus species indicates that the applicability of yeast-based models to fully describe and explain the stress-responses of these fungi is limited. Most excitingly, putative orthologues of both Saccharomyces cerevisiae Msn2p/Msn4p C2H2 zinc finger-type and Schizosaccharomyces pombe Atf1 bZip-type 1general stress' transcription factors were annotated in the aspergilli, foreshadowing complex and robust stress defence systems in these euascomycetes.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban Aspergillus, Stress-response Mitogen-activated protein kinase Environmental stress-response HOG pathway Osmotic stress Genome annotation Comparative genomics Neurospora crassa Schizosaccharomyces pombe Saccharomyces cerevisiae DNA repair Starvation stress Unfolded protein response Thermal stress Oxidative stress
Megjelenés:	Fungal Genetics and Biology 46 : 1 Suppl.1 (2009), p. 105-120. -
További szerzők:	Karányi Zsolt (1961-) (biostatisztikus, bioinformatikus) Pócsi István (1961-) (vegyész)
Internet cím:	elektronikus változat elektronikus változat DOI
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