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001-es BibID:	BIBFORM033289
035-os BibID:	(WOS)A1981MD06600006 (scopus)0019829403
Első szerző:	Bartosz, G.
Cím:	Aging of the erythrocyte : IX. Fluorescence studies on changes in membrane properties / G. Bartosz, G. Szabo, J. Szollosi, J. Szollosi, S. Damjanovich
Dátum:	1981
Megjegyzések:	Fluorescence studies of membranes prepared from density-separated red blood cells demonstrated an increase in lipid viscosity (judging from fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene and 1-aminonaphthalene-8-sulfonate and changes in the physical state of proteins (judging from tryptophan fluorescence intensity and polarization). These alterations may be partly due to lipid peroxidation. In vivo accumulation of products of this process in the membranes was confirmed. Changes were also found in the distribution pattern of cell populations of different mean age in a cell sorter, probably due to alterations in rheological properties of the erythrocytes.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Aging Animal blood Cattle Diphenylhexatriene Erythrocyte Aging Erythrocyte Membrane Erythrocytes Fluorescence Fluorescence Polarization Lipid Peroxidation Lipid Peroxides Membrane Fluidity metabolism Naphthalenesulfonates physiology Proteins Spectrometry, Fluorescence Support, Non-U.S.Gov't Temperature Tryptophan Viscosity egyetemen (Magyarországon) készült közlemény
Megjelenés:	Mechanisms of Ageing and Development. - 16 : 3 (1981), p. 265-274. -
További szerzők:	Szabó Gábor (1953-) (biofizikus) Szöllősi János (1953-) (biofizikus) Szöllősi J. Damjanovich Sándor (1936-2017) (biofizikus)
Internet cím:	elektronikus változat DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM033270
035-os BibID:	WOS:000166627300004 PMID:11163624
Első szerző:	Imre Sándor (pathofiziológus)
Cím:	High sensitivity to autoxidation in neonatal calf erythrocytes : possible mechanism of accelerated cell aging / S. Imre, M. Csornai, M. Balazs
Dátum:	2001
Megjegyzések:	The suspension viscosity, formation of methaemoglobin and production of malondialdehyde (MDA) associated with the non-enzymatic oxidation of polyunsaturated fatty acids during auto-oxidation conditions in vitro have been compared in erythrocytes From young calves (2, 4 and 6 weeks of age) and mature cattle. The autoxidation conditions were designed to simulate the oxidative stress to which neonatal erythrocytes are exposed in vivo. Characterisation of lipid peroxidation was also undertaken by a combination of lipid fluorescent measurements and quantification of the superoxide: dismutase (SOD) activities of the erythrocytes, The results demonstrated that high SOD activities in the erythrocytes of the neonatal calf was insufficient to afford protection against the increased autoxidation of haemoglobin and subsequent accumulation of lipid peroxidation products, High levels of methaemoglobin formation and lipid peroxidation were able to provide an explanation for an observed reduction in rheological adaptability (increased suspension viscosity) and an accelerated aging of the neonatal cells under in vivo conditions.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban Superoxide dismutase Lipid peroxidation Autoxidation Rheology Calf erythrocytes egyetemen (Magyarországon) készült közlemény
Megjelenés:	Mechanisms of ageing and development. - 122 : 1 (2001), p. 69-76. -
További szerzők:	Csornai Márta Balázs Margit (1952-) (sejtbiológus, molekuláris genetikus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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