CCL

Összesen 20 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM076596
Első szerző:Baló-Banga Mátyás
Cím:A novel rapid (20-minute) IL-6 release assay using blood mononuclear cells of patients with various clinical forms of drug induced skin injuries / Baló-Banga Joseph M., Schweitzer Katalin, Lakatos Susan, Sipka Sándor
Dátum:2015
ISSN:1939-4551
Megjegyzések:Background: IL-6 is a pro-inflammatory cytokine which has many well-defined effects. Its synthesis and release from mononuclear cells of drug-sensitized patients was related before to in vitro drug-allergy diagnostics but has not yet been studied in detail. Methods: The specific release of preformed IL-6 from peripheral blood mononuclear cells (PBMC) after 20 minutes incubation with 0.15?0.5 ?M of pure drugs was measured in two groups of drug-allergy suspected donors (159) and respective controls (48). IL-6, TNF-alpha, IL-2, IL-4, IFN-gamma have been measured from cell supernatants by ELISA or by cytometric bead assay. Epicutaneous, intradermal and systemic provocation tests were performed to prove or disprove culprit substances (203 in vivo against 482 in vitro tests). T-test (paired and unpaired); chi2 contingency table; Z statistics and McNemar's test were used to evaluate results. Results: Concanavalin A as positive control released IL-6 from PBMC in linear concentration and exponential time dependent fashion (up to 60 minutes) pointing to the existence of a preformed pool of this cytokine. Preformed IL-6 released at any of 4 standard drug dilutions tested, above 50% over their diluents' levels significantly correlated with the patients' history on drug-induced hypersensitivity symptoms and with in vivo tests. Sensitivity of 85.4% and specificity of 82.4% of the IL-6 release assay were found. The 20· drop in release of TNF-alpha had no diagnostic importance; it has accompanied increased IL-6 release. IL-2, IL-4 and IFN-gamma were undetectable in 20 minutes supernatants. IL-6 release depended on the clinical phenotype but not on the eliciting drug(s) in the molecular mass range of 76?4000 Da. Reactivity of mononuclear cells at the lowest or at multiple drug test concentrations reflected clinical severity per diagnoses and according to area of skin involvement. Conclusion: This rapid test is applicable to detect a wide scale of drug hypersensitivity
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
IL-6
TNF-alpha
T-lymphocytes
Drug-induced skin injury
Adverse drug reactions
Preformed cytokines' release
Megjelenés:World Allergy Organization Journal. - 8 : 1 (2015), p. 1-11. -
További szerzők:Schweitzer Katalin Lakatos Susan Sipka Sándor (1945-) (laboratóriumi szakorvos)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM060688
Első szerző:Chen, Ji-Qing
Cím:Toll-Like Receptor Pathways in Autoimmune Diseases / Ji-Qing Chen, Peter Szodoray, Margit Zeher
Dátum:2016
ISSN:1080-0549
Megjegyzések:Autoimmune diseases are a family of chronic systemic inflammatory disorders, characterized by the dysregulation of the immune system which finally results in the break of tolerance to self-antigen. Several studies suggest that Toll-like receptors (TLRs) play an essential role in the pathogenesis of autoimmune diseases. TLRs belong to the family of pattern recognition receptors (PRRs) that recognize a wide range of pathogen-associated molecular patterns (PAMPs). TLRs are type I transmembrane proteins and located on various cellular membranes. Two main groups have been classified based on their location; the extracelluar group referred to the ones located on the plasma membrane while the intracellular group all located in endosomal compartments responsible for the recognition of nucleic acids. They are released by the host cells and trigger various intracellular pathways which results in the production of proinflammatory cytokines, chemokines, as well as the expression of co-stimulatory molecules to protect against invading microorganisms. In particular, TLR pathway-associated proteins, such as IRAK, TRAF, and SOCS, are often dysregulated in this group of diseases. TLR-associated gene expression profile analysis together with single nucleotide polymorphism (SNP) assessment could be important to explain the pathomechanism driving autoimmune diseases. In this review, we summarize recent findings on TLR pathway regulation in various autoimmune diseases, including Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), multiple sclerosis (MS), rheumatoid arthritis (RA), systemic sclerosis (SSc), and psoriasis.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Toll-like receptors (TLRs)
Autoimmune disease
IL-1-receptor-associated kinase (IRAK)
TNF-receptor-associated factor (TRAF)
Suppressor of cytokine signaling (SOCS)
Megjelenés:Clinical Reviews In Allergy & Immunology 50 : 1 (2016), p. 1-17. -
További szerzők:Szodoray Péter (1973-) (belgyógyász, orvos) Zeher Margit (1957-2018) (belgyógyász, allergológus és klinikai immunológus, reumatológus)
Pályázati támogatás:TÁMOP-4.2.2.A-11/1/KONV-2012-0023
TÁMOP
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM003596
Első szerző:Irinyi Beatrix (bőrgyógyász, allergológus)
Cím:Clinical and laboratory examinations in the subgroups of chronic urticaria / Irinyi B., Széles Gy., Gyimesi E., Tumpek J., Herédi E., Dimitrios G., Ádány R., Hunyadi J., Szegedi A.
Dátum:2007
Megjegyzések:The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35 %, autoimmune urticaria (AIU) at 25 % and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. Methods: Differences in clinical and laboratory parameters among AIU, PU and CIU groups were examined. AIU was diagnosed if basophil CD63 assay was positive. Demographic data, severity of symptoms, and association with allergic and autoimmune diseases were analysed by the aid of an internationally accepted questionnaire a questionnarie. Immunoassays were carried out and the effectiveness of therapy was also investigated. Results: Female dominance in the AIU group was prominent. Concerning the urticaria score, there were significant differences between the AIU and PU patients (p=0.015) and between AIU and CIU cases (p=0.013). Between the CIU and PU patients, we found an insignificant difference in the urticaria score (p=0.78). AIU was more frequently associated with autoimmune diseases in the personal (p<0.001), and with other types of urticaria in the family history (p<0.001). Also anti-thyroid antibodies were more frequently detected in the AIU group. Antihistamine therapy was less effective in the AIU group (12.8%) than in the PU (70.3%) and CIU groups (68.6 %), but there were no significant differences between the CIU and PU groups regarding the effectiveness of antihistamine therapy. Conclusion: The autoimmune subgroup represents the most severe form of chronic urticaria. On the other hand between the CIU and PU groups there were no significant differences in urticaria scores as well as in response to antihistamine therapy. Key words: antihistamine therapy, autoimmune urticaria, physical urticaria, chronic idiopathic urticaria
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
chronic urticaria
Megjelenés:International Archives of Allergy and Immunology 144 : 3 (2007), p. 217-225. -
További szerzők:Széles György (1969-) (epidemiológus) Gyimesi Edit (1957-) (klinikai biokémikus, vegyész) Tumpek Judit (1944-) (orvosi laboratóriumi szakorvos) Herédi Emese (1979-) (bőrgyógyász) Dimitrios, Georgitsis Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) Hunyadi János (1943-) (bőrgyógyász, kozmetológus, allergológus) Szegedi Andrea (1964-) (bőrgyógyász)
Internet cím:elektronikus változat
DOI
Borító:

4.

001-es BibID:BIBFORM086310
Első szerző:Jámbor Ilona (orvosi biotechológus)
Cím:The imbalance of peripheral follicular T helper cell subsets is associated with abnormal B- cell distribution and disease severity in primary Sjögren's syndrome / Jámbor I., Papp G., Zeher M., Szántó A., Szabó K.
Dátum:2019
ISSN:0105-4538 1398-9995
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Allergy. - 74 : S106 (2019), p. 243. -
További szerzők:Papp Gábor (1984-) (belgyógyász) Zeher Margit (1957-2018) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Szántó Antónia (1977-) (belgyógyász, allergológus és klinikai immunológus) Szabó Krisztina (1987-) (Molekuláris biológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM044038
Első szerző:Kurkó Júlia Emese (reumatológus)
Cím:Genetics of Rheumatoid Arthritis : a Comprehensive Review / Kurkó Júlia, Besenyei Timea, Laki Judit, Glant Tibor T., Mikecz Katalin, Szekanecz Zoltán
Dátum:2013
ISSN:1080-0549
Megjegyzések:The "Bermuda triangle" of genetics, environment and autoimmunity is involved in the pathogenesis of rheumatoid arthritis (RA). Various aspects of genetic contribution to the etiology, pathogenesis and outcome of RA are discussed in this review. The heritability of RA has been estimated to be about 60 %, while the contribution of HLA to heritability has been estimated to be 11-37 %. Apart from known shared epitope (SE) alleles, such as HLA-DRB1*01 and DRB1*04, other HLA alleles, such as HLA-DRB1*13 and DRB1*15 have been linked to RA susceptibility. A novel SE classification divides SE alleles into S1, S2, S3P and S3D groups, where primarily S2 and S3P groups have been associated with predisposition to seropositive RA. The most relevant non-HLA gene single nucleotide polymorphisms (SNPs) associated with RA include PTPN22, IL23R, TRAF1, CTLA4, IRF5, STAT4, CCR6, PADI4. Large genome-wide association studies (GWAS) have identified more than 30 loci involved in RA pathogenesis. HLA and some non-HLA genes may differentiate between anti-citrullinated protein antibody (ACPA) seropositive and seronegative RA. Genetic susceptibility has also been associated with environmental factors, primarily smoking. Some GWAS studies carried out in rodent models of arthritis have confirmed the role of human genes. For example, in the collagen-induced (CIA) and proteoglycan-induced arthritis (PgIA) models, two important loci - Pgia26/Cia5 and Pgia2/Cia2/Cia3, corresponding the human PTPN22/CD2 and TRAF1/C5 loci, respectively - have been identified. Finally, pharmacogenomics identified SNPs or multiple genetic signatures that may be associated with responses to traditional disease-modifying drugs and biologics
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Rheumatoid arthritis
Murine arthritis
Genetics
Single nucleotide polymorphisms
HLA-DR
GWAS
Megjelenés:Clinical Reviews In Allergy & Immunology 45 : 2 (2013), p. 170-179. -
További szerzők:Besenyei Tímea (1980-) (reumatológus, belgyógyász) Laki Judit Glant Tibor T. Mikecz Katalin Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

6.

001-es BibID:BIBFORM025043
Első szerző:Nagy Georgina (orvosbiológus)
Cím:Association between Serum IL-16 Levels and the Degree of Sensitization in Patients with Atopic Dermatitis / Nagy Georgina, Gáspár Krisztián, Irinyi Beatrix, Gál Mónika, Tumpek Judit, Gyimesi Edit, Sipka Sándor, Remenyik Éva, Szodoray Péter, Szegedi Andrea
Dátum:2011
ISSN:1018-2438
Megjegyzések:Background: Interleukin (IL)-16 has been characterized as animmunomodulatory cytokine. Besides its chemotactic properties,IL-16 amplifies inflammatory processes and possessesimmunoregulatory functions. Our aim was to investigate theassociation between serum IL-16 levels and the degree of allergicsensitization in patients with atopic dermatitis (AD).Methods: The serum level of IL-16 was measured by immunoenzymaticassays. Eosinophil cell count, serum total andspecific IgE levels were assessed; prick tests were also carriedout. Based on specific IgE levels and prick tests, AD patientswere divided into sensitized and nonsensitized subgroups,and correlations among serum IL-16, total IgE levels and eosinophilcell counts were measured in the total patient groupand in subgroups. Results: In the total patient group, significantlyhigher levels of IL-16 were found in the sera of patientswith AD, compared to healthy individuals and patientswith psoriasis. A significant correlation was detected betweenserum levels of IL-16 and total IgE, total IgE andeosinophil counts, but not between IL-16 and eosinophils.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Interleukin-16
Atopic dermatitis
Cytokines
Megjelenés:International Archives Of Allergy And Immunology 156 : 1 (2011), p. 69-74. -
További szerzők:Gáspár Krisztián (1974-) (bőrgyógyász) Irinyi Beatrix (1972-) (bőrgyógyász, allergológus) Gál Mónika Tumpek Judit (1944-) (orvosi laboratóriumi szakorvos) Gyimesi Edit (1957-) (klinikai biokémikus, vegyész) Sipka Sándor (1945-) (laboratóriumi szakorvos) Remenyik Éva (1956-) (bőrgyógyász) Szodoray Péter (1973-) (belgyógyász, orvos) Szegedi Andrea (1964-) (bőrgyógyász)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

7.

001-es BibID:BIBFORM057210
Első szerző:Nakken, Britt
Cím:Cytokine milieu in undifferentiated connective tissue disease : a comprehensive review / Britt Nakken, Edit Bodolay, Peter Szodoray
Dátum:2015
ISSN:1080-0549
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Clinical Reviews In Allergy & Immunology 49 : 2 (2015), p. 152-162. -
További szerzők:Bodolay Edit (1950-) (belgyógyász, allergológus és klinikai immunológus) Szodoray Péter (1973-) (belgyógyász, orvos)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

8.

001-es BibID:BIBFORM015838
Első szerző:Orbach, Hedi
Cím:Prolactin and Autoimmunity : hyperprolactinemia Correlates with Serositis and Anemia in SLE Patients / Orbach, H., Zandman-Goddard, G., Boaz, M., Agmon-Levin, N., Amital, H., Szekanecz, Z., Szucs, G., Rovensky, J., Kiss, E., Doria, A., Ghirardello, A., Gomez-Arbesu, J., Stojanovich, L., Ingegnoli, F., Meroni, P. L., Rozman, B., Blank, M., Shoenfeld, Y.
Dátum:2012
ISSN:1559-0267 (Electronic)
Megjegyzések:Evidence points to an association of prolactin to autoimmune diseases. We examined the correlation between hyperprolactinemia and disease manifestations and activity in a large patient cohort. Age- and sex-adjusted prolactin concentration was assessed in 256 serum samples from lupus patients utilizing the LIASON prolactin automated immunoassay method (DiaSorin S.p.A, Saluggia, Italy). Disease activity was defined as present if European Consensus Lupus Activity Measurement (ECLAM) > 2 or Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) > 4. Lupus manifestations were grouped by organ involvement, laboratory data, and prescribed medications. Hyperprolactinemia was presented in 46/256 (18%) of the cohort. Hyperprolactinemic patients had significantly more serositis (40% vs. 32.4%, p = 0.03) specifically, pleuritis (33% vs. 17%, p = 0.02), pericarditis (30% vs. 12%, p = 0.002), and peritonitis (15% vs. 0.8%, p = 0.003). Hyperprolactinemic subjects exhibited significantly more anemia (42% vs. 26%, p = 0.02) and marginally more proteinuria (65.5% vs. 46%, p = 0.06). Elevated levels of prolactin were not significantly associated with other clinical manifestations, serology, or therapy. Disease activity scores were not associated with hyperprolactinemia. Hyperprolactinemia in lupus patients is associated with all types of serositis and anemia but not with other clinical, serological therapeutic measures or with disease activity. These results suggest that dopamine agonists may be an optional therapy for lupus patients with hyperprolactinemia.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Clinical Reviews in Allergy and Immunology. - 42 : 2 (2012), p. 189-198. -
További szerzők:Zandman-Goddard, Gisele Boaz, Mona Agmon-Levin, Nancy Amital, Howard Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Rovensky, Josef Kiss Emese (1960-) (belgyógyász, immunológus) Doria, Andrea Ghirardello, A. Gomez-Arbesu, Jesus Stojanovich, Ljudmila Ingegnoli, Francesca Meroni, Pier Luigi Rozman, Blaz Blank, Marion Shoenfeld, Yehuda
Internet cím:DOI
elektronikus változat
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

9.

001-es BibID:BIBFORM083567
035-os BibID:(WoS)000480254003094
Első szerző:Papp Gábor (belgyógyász)
Cím:Investigation on the immunological effects of regular physical exercise / Papp Gábor, Szabó Krisztina, Jámbor Ilona, Mile Marianna, Csiki Zoltán, Balogh László
Dátum:2019
ISSN:0105-4538 1398-9995
Megjegyzések:Background : Growing evidence shed light on the significant effects of physical activity on immunomodulation. Consequences may largely depend on the type of activity, its intensity and duration. However, little information is available regarding the immunological effects of sporting activities in older ages. The aim of our study was to examine the changes in a wide spectrum of lymphocyte subtypes after a period of regular workout among healthy women of different ages. Method : In a cross- sectional study, we enrolled 34 young adult women (between ages of 19- 23 years), 8 of them were a player of a team in Hungarian Women ' s Volleyball League, while 26 of them were not engaged in regular physical activity. Additionally, we enrolled 16 elderly women (between ages of 60- 75 years) not engaged in regular physical activity. During a follow- up study, 17 from the group of non- athlete young adults completed a 12- week Pilates workout program, while the group of elderly women took part in a 6- week lightweight conditioning gymnastic exercise program once a week. The percentages of peripheral natural killer (NK), NKT cells, T and B lymphocyte subtypes (early- /late- activated T, naive and memory T, cytotoxic T (Tc), T- helper (Th)1, Th2, Th17, T regulatory type 1 (Tr1), CD4 + CD127- CD25 bright Treg, as well as naive and memory B cells) were determined by flow cytometry based on the staining of extracellular markers and intracellular cytokines. Results : The investigated baseline parameters did not show significant differences between athlete and non- athlete young adults. In the elderly, levels of CD3 + 6B11 + NKT cells were lower, while ratios of CD4 + Th/CD8 + Tc cells were higher compared to the values of younger individuals. At the end of exercise programs, changes observed among 60- 75 year- olds were more pronounced compared to alterations developed in younger subjects. In elderly women, percentages of IgD+ naive B cells decreased, while levels of CD27 + switched- memory B cells increased. Furthermore, proportions of CD4 + IL- 4 + Th2 cells increased, while levels of CD8 + IFNgamma+ Tc cells and immunosuppressive CD4 + CD127- CD25 bright Treg cells decreased as the result of regular exercise. Conclusion : Differences observed after lightweight exercise programs reflect a presumably enhanced immunoreactivity and increased ability for immune responses, especially in older ages. The research was supported by the GINOP- 2.3.2- 15- 2016- 00062 project. The project is co- financed by the European Union from the European Regional Development Fund.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Allergy. - 74 : S106 (2019), p. 421. -
További szerzők:Szabó Krisztina (1987-) (Molekuláris biológus) Jámbor Ilona (1985-) (orvosi biotechológus) Mile Marianna (1977-) (gyógytornász) Csiki Zoltán (1962-) (belgyógyász, allergológus, klinikai immunológus, reumatológus) Balogh László (1976-) (kardiológus)
Pályázati támogatás:GINOP-2.3.2-15-2016-00062
GINOP
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

10.

001-es BibID:BIBFORM001939
Első szerző:Sümegi Andrea (biológus)
Cím:Analysis of components of the CD14/TLR system on leukocytes of patients with atopic dermatitis / Sümegi A., Szegedi A., Gál M., Hunyadi J., Szegedi G., Antal-Szalmás P.
Dátum:2007
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
atopic dermatitis
CD14
toll-like receptor 2
toll-like receptor 4
CD180
Megjelenés:International Archives of Allergy and Immunology. - 143 : 3 (2007), p. 177-184. -
További szerzők:Szegedi Andrea (1964-) (bőrgyógyász) Gál Mónika Hunyadi János (1943-) (bőrgyógyász, kozmetológus, allergológus) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Antal-Szalmás Péter (1968-) (laboratóriumi szakorvos)
Internet cím:elektronikus változat
DOI
Borító:

11.

001-es BibID:BIBFORM086311
Első szerző:Szabó Krisztina (Molekuláris biológus)
Cím:Alteration in the proportions of circulating follicular T helper cell subsets is related to aberrant B cell distribution and antibody production in patients with systemic lupus erythematosus / Szabó K., Jámbor I., Tarr T., Papp G.
Dátum:2019
ISSN:0105-4538 1398-9995
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Allergy. - 74 : S106 (2019), p. 243. -
További szerzők:Jámbor Ilona (1985-) (orvosi biotechológus) Tarr Tünde (1976-) (belgyógyász, allergológus és klinikai immunológus) Papp Gábor (1984-) (belgyógyász)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

12.

001-es BibID:BIBFORM038690
035-os BibID:PMID:14763929
Első szerző:Szakos Erzsébet
Cím:Association between the occurrence of the anticardiolipin IgM and mite allergen-specific IgE antibodies in children with extrinsic type of atopic eczema/dermatitis syndrome / E. Szakos, G. Lakos, M. Aleksza, E. Gyimesi, G. Páll, B. Fodor, J. Hunyadi, E. Sólyom, S. Sipka
Dátum:2004
ISSN:0105-4538
Megjegyzések:AbstractBACKGROUND: As the literature has only controversial data on the role of nonallergen-specific antibodies in atopic eczema dermatitis syndrome, the authors investigated the link between the occurrence of the antiphospholipid [anticardiolipin (ACL), anti-beta2-glycoprotein I] and allergen-specific immunoglobulin E (IgE) antibodies in 72 children with atopic eczema/dermatitis syndrome (AEDS).METHODS: The measurement of antiphospholipid antibodies was carried out by enzyme-linked immunosorbent assay (ELISA), serum total IgE by nephelometry, and allergen-specific IgE by immunoblotting assay. The statistical analysis was carried out by Fisher's exact test and odds ratio was calculated.RESULTS: Thirteen of 72 children with AEDS (mean age 8.3 years) had elevated serum levels of ACL, and eight anti-beta2-glycoprotein I antibodies. The presence of allergen-specific IgE against inhalant allergens and nutritive allergens was among eight of 13 and three of eight in the cases with elevated ACL. The ratio of patients with highly increased severity scoring of atopic dermatitis (SCORAD) index (>75) was significantly higher in the group with elevated (4/13) than in those with the normal ACL levels (2/59). There was a significant association between the appearance of mite (Dermatophagoides pteronyssinus, D. farinae)-specific IgE and ACL IgM antibodies (6/13).CONCLUSION: These findings show that there are significant linkage and association between the appearance of ACL IgM or the production of allergen-specific IgE against inhalant (mainly mite) allergens in children with atopic eczema/dermatitis syndrome.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
eczema
anticardiolipin
mite specific IgE
atopic dermatitis
egyetemen (Magyarországon) készült közlemény
Megjelenés:Allergy. - 59 : 2 (2004), p. 164-167. -
További szerzők:Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Aleksza Magdolna Páll Gabriella Fodor Bertalan Hunyadi János (1943-) (bőrgyógyász, kozmetológus, allergológus) Sólyom Enikő Sipka Sándor (1945-) (laboratóriumi szakorvos) Gyimesi Edit (1957-) (klinikai biokémikus, vegyész)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1 2 
Corvina könyvtári katalógus v8.2.27 © 2023 Monguz kft. Minden jog fenntartva.