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001-es BibID:	BIBFORM077568
Első szerző:	Szűcs Miklós (urológus, andrológus)
Cím:	Hyaluronan bound mature sperm count (HB-MaSC) is a more informative indicator of fertility than conventional sperm parameters : correlations with Body Mass Index (BMI) / Miklos Szucs, Peter Osvath, Attila Jakab, Daniel Varga, Balazs Varga, Bela Juhasz
Dátum:	2019
ISSN:	1642-431X
Megjegyzések:	The relationship between overweight and male fertility is well studied, still the correlation of obesity and de- creased sperm quality is a subject to debate. The widely used conventional spermatological examinations alone seem to be inadequate to assess fertilization potential. Hyaluronan Binding Assay (HBA?) is one of the available validated tests that allows the functional examination of sperm. Data of 72 male patients (mean age 33.9 (24?43) years) from infertile couples were analysed. Body Mass Index (BMI) determination, conventional semen analysis and HBA were performed. Additionally, a relatively new Hyaluronan Bound Matured Sperm Count (HB-MaSC) -index, first introduced by the authors in 2015, was calculated. This index reflects fertilization potential of sperm more precisely. With the increase of BMI, sperm count decreased significantly until about 25kg/m2, above 25 kg/m2 no further decrease was observed, although sperm count remained permanently low. Greater body weight (in the 70?90 kg range) was observed to have a significant negative effect only on the progressive sperm motility. In addition to sperm concentration and motility, sperm fertilization potential is also negatively affected by obesity, but is irrespective of body weight, as evaluated using BMI + HB-MaSC linear regression analyses adjusted for age and weight. This correlation between male BMI and sperm fertilization potential ? as opposed to the conventional correlations with sperm concentration or motility ? appears to provide more helpful in- formation in the identification of real capability for fertilization.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban sperm quality obesity sperm function hyaluronan binding
Megjelenés:	Reproductive Biology. - 19 : 1 (2019), p. 38-44. -
További szerzők:	Osváth Péter (1982-) (Urológus szakorvos) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Varga Dániel (1990-) (általános orvos) Varga Balázs (1984-) (kísérletes farmakológus) Juhász Béla (1978-) (kísérletes farmakológus)
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001-es BibID:	BIBFORM084241
Első szerző:	Takács Péter (szülész-nőgyógyász)
Cím:	The effect of oral zinc supplementation on cervicovaginal lavage fluid zinc level / Takacs Peter, Damjanovich Peter, Sipos Attila Gergely, Kozma Bence
Dátum:	2020
ISSN:	0301-2115
Megjegyzések:	Objectives: To investigate the effect of oral zinc supplementation on cervicovaginal lavage fluid (CVL) zinc level in pre and postmenopausal women. Study design: A prospective interventional cohort study was carried out by the enrollment of twelve premenopausal and ten postmenopausal women without significant gynecological conditions. Women received daily oral supplementation with 30?mg of zinc for two weeks. Clinical and demographic variables were stored in a dedicated database. Vaginal Health Index was calculated, and vaginal cytology was obtained. CVL and serum samples were collected in a standardized fashion before and after completion of the oral supplementation. Zinc and copper levels were measured by inductively coupled plasma optical emission spectrometry. Paired t-test was used to compare the before and after treatment results. Results: Serum zinc levels increased significantly both in the pre and postmenopausal women (0.88???0.17 vs. 1.06???0.23, p?<?0.01 and 0.83???0.24 vs. 0.96???0.33, p?<?0.01) after two weeks of daily oral zinc supplementation. CVL zinc level was significantly higher in the premenopausal group compared to the postmenopausal group before and after supplementation (0.13???0.05 vs. 0.06???0.04, p?<?0.01 and 0.10???0.03 vs. 0.05???0.01, p?<?0.01). Zinc supplementation had no significant impact on the CVL zinc level in either group. Neither serum nor CVL copper levels were affected by the zinc supplementation. There was no significant correlation between serum and CVL zinc or copper levels. Conclusion: Daily oral supplementation with 30?mg of zinc had no significant impact on CVL zinc level despite a significant rise in serum zinc level.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Zinc Cooper Cervicovaginal lavage Vaginal Health Index Maturation value
Megjelenés:	European Journal Of Obstetrics Gynecology And Reproductive Biology. - 248 (2020), p. 106-109. -
További szerzők:	Damjanovich Péter Gábor (1985-) (szülész-nőgyógyász) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Kozma Bence (1982-) (szülész-nőgyógyász)
Pályázati támogatás:	GINOP-2.1.1-15-2016-00783 GINOP
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