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001-es BibID:	BIBFORM103776
035-os BibID:	(cikkazonosító)1000688 (WOS)000871611300001 (Scopus)85138178796
Első szerző:	Farkas Zsuzsa
Cím:	Probabilistic modeling and risk characterization of the chronic aflatoxin M1 exposure of Hungarian consumers / Zsuzsa Farkas, Kata Kerekes, Árpád Ambrus, Miklós Süth, Ferenc Peles, Tünde Pusztahelyi, István Pócsi, Attila Nagy, Péter Sipos, Gabriella Miklós, Anna Lőrincz10, Szilveszter Csorba, Ákos Bernard Jóźwiak
Dátum:	2022
ISSN:	1664-302X
Megjegyzések:	Aflatoxin contamination can appear in various points of the food chain. If animals are fed with contaminated feed, AFB1 is transformed?among others?to aflatoxin M1 (AFM1) metabolite. AFM1 is less toxic than AFB1, but it is still genotoxic and carcinogenic and it is present in raw and processed milk and all kinds of milk products. In this article, the chronic exposure estimation and risk characterization of Hungarian consumers are presented, based on the AFM1 contamination of milk and dairy products, and calculated with a probabilistic method, the two-dimensional Monte-Carlo model. The calculations were performed using the R plugin (mc2d package) integrated into the KNIME (Konstanz Information Miner) software. The imulations were performed using data from the 2018?2020 food consumption survey. The AFM1 analytical data were derived from the Hungarian monitoring survey and 1,985 milk samples were analyzed within the framework of the joint project of the University of Debrecen and the National Food Chain Safety Office of Hungary (NÉBIH). Limited AFM1 concentrations were available for processed dairy products; therefore, a database of AFM1 processing factors for sour milk products and various cheeses was produced based on the latest literature data, and consumer exposure was calculated with the milk equivalent of the consumed quantities of these products. For risk characterization, the calculation of hazard index (HI), Margin of Exposure, and the hepatocellular carcinoma incidence were used. The results indicate that the group of toddlers that consume a large amount of milk and milk products are exposed to a certain level of health risk. The mean estimated daily intake of toddlers is in the range of 0.008?0.221ngkg?1 bw day?1; the 97.5th percentile exposure of toddlers is between 0.013ngkg?1 bw day?1 and 0.379ngkg?1 bw day?1, resulting in a HI above 1. According to our study, the exposure of older age groups does not pose an emergent health risk. Nevertheless, the presence of carcinogenic compounds should be kept to a minimum in the whole population.
Tárgyszavak:	Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk AFM1 mycotoxin exposure assessment probabilistic method
Megjelenés:	Frontiers in Microbiology. - 13 (2022), p. 1-12. -
További szerzők:	Kerekes Kata Ambrus Árpád Süth Miklós Peles Ferenc (1979-) (mikrobiológia, élelmiszer-mikrobiológia, minőségügy) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító) Pócsi István (1961-) (vegyész) Nagy Attila Sipos Péter (1975-) (agrármérnök) Miklós Gabriella Lőrincz Anna Csorba Szilveszter Jóźwiak Ákos
Pályázati támogatás:	2018-1.2.1-NKP-2018-00002 Egyéb
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001-es BibID:	BIBFORM116975
035-os BibID:	(cikkazonosító)1260166 (WoS)001143637400001 (Scopus)85182399795
Első szerző:	Krishnan, S. Vipin
Cím:	Fusarium biocontrol : antagonism and mycotoxin elimination by lactic acid bacteria / S. Vipin Krishnan, K. Madhavan Nampoothiri, Anandhu Suresh, Nguyen Thuy Linh, P. A. Balakumaran, István Pócsi, Tünde Pusztahelyi
Dátum:	2024
ISSN:	1664-302X
Megjegyzések:	Mycotoxins produced by Fusarium species are secondary metabolites with low molecular weight formed by filamentous fungi generally resistant to different environmental factors and, therefore, undergo slow degradation. Contamination by Fusarium mycotoxins in cereals and millets is the foremost quality challenge the food and feed industry faces across the globe. Several types of chemical preservatives are employed in the mitigation process of these mycotoxins, and they help in long-term storage; however, chemical preservatives can be used only to some extent, so the complete elimination of toxins from foods is still a herculean task. The growing demand for green-labeled food drives to evade the use of chemicals in the production processes is getting much demand. Thus, the biocontrol of food toxins is important in the developing food sector. Fusarium mycotoxins are world-spread contaminants naturally occurring in commodities, food, and feed. The major mycotoxins Fusarium species produce are deoxynivalenol, fumonisins, zearalenone, and T2/HT2 toxins. Lactic acid bacteria (LAB), generally regarded as safe (GRAS), is a well-explored bacterial community in food preparations and preservation for ages. Recent research suggests that LAB are the best choice for extenuating Fusarium mycotoxins. Apart from Fusarium mycotoxins, this review focuses on the latest studies on the mechanisms of how LAB effectively detoxify and remove these mycotoxins through their various bioactive molecules and background information of these molecules.
Tárgyszavak:	Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk lactic acid bacteria Fusarium mycotoxin antagonism biocontrol bioactive biocontrol mycotoxins
Megjelenés:	Frontiers in Microbiology. - 14 (2024), p. 1-17. -
További szerzők:	Nampoothiri K. Madhavan Suresh, Anandhu Nguyen Thuy Linh Balakumaran P. A. Pócsi István (1961-) (vegyész) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító)
Pályázati támogatás:	2019-2.1.13-TÉT_IN-2020-00056 Egyéb TKP2021-NKTA-32 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM106701
035-os BibID:	(cikkazonosító)1085891 (WoS)000929068300001 (Scopus)85147698175
Első szerző:	Loi, Martina
Cím:	Advanced mycotoxin control and decontamination techniques in view of an increased aflatoxin risk in Europe due to climate change / Martina Loi, Antonio F. Logrieco, Tünde Pusztahelyi, Éva Leiter, László Hornok, István Pócsi
Dátum:	2023
ISSN:	1664-302X
Megjegyzések:	Aflatoxins are toxic secondary metabolites produced by Aspergillus spp. found in staple food and feed commodities worldwide. Aflatoxins are carcinogenic, teratogenic, and mutagenic, and pose a serious threat to the health of both humans and animals. The global economy and trade are significantly affected as well. Various models and datasets related to aflatoxins in maize have been developed and used but have not yet been linked. The prevention of crop loss due to aflatoxin contamination is complex and challenging. Hence, the set-up of advanced decontamination is crucial to cope with the challenge of climate change, growing population, unstable political scenarios, and food security problems also in European countries. After harvest, decontamination methods can be applied during transport, storage, or processing, but their application for aflatoxin reduction is still limited. Therefore, this review aims to investigate the effects of environmental factors on aflatoxin production because of climate change and to critically discuss the present-day and novel decontamination techniques to unravel gaps and limitations to propose them as a tool to tackle an increased aflatoxin risk in Europe
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk aflatoxin climate change models mycotoxin control decontamination techniques
Megjelenés:	Frontiers in Microbiology. - 13 (2023), p. 1-18. -
További szerzők:	Logrieco, Antonio F. Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító) Leiter Éva (1976-) (biológus) Hornok László Pócsi István (1961-) (vegyész)
Pályázati támogatás:	2018-1.2.1-NKP-2018- 00002 Egyéb TKP2021-EGA-20 810 Egyéb K142801 Egyéb No 952337 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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