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001-es BibID:	BIBFORM115171
035-os BibID:	(WoS)001081655000001 (Scopus)85173726282
Első szerző:	Kovács Nóra (népegészségügyi szakember)
Cím:	Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary : a study on the challenges of unhealthy aging / Kovacs Nora, Piko Peter, Juhasz Attila, Nagy Csilla, Oroszi Beatrix, Ungvari Zoltan, Adany Roza
Dátum:	2024
ISSN:	2509-2715 2509-2723
Megjegyzések:	The demographic transition poses a significant challenge for health systems, especially in Central and Eastern European (CEE) countries, where the healthcare needs of aging populations are on the rise. This study aimed to describe and compare the health status and utilization of health services among the elderly residing in urban and rural areas of the most deprived region in Hungary. A comprehensive health survey was conducted in 2022, involving a randomly selected sample of 443 older adults (??65 years) in Northeast Hungary. Multivariable logistic regression models adjusting for age, sex, education, financial status, chronic diseases, and activity limitations were used to investigate the association between type of residence and health service use. Among the study participants, 62.3% were female, 38.3% attained primary education, 12.5% reported a bad or very bad financial situation and 52.6% lived in urban areas. Overall, 24% of the elderly rated their health as very good or good (27.8% in urban and 19.7% in rural areas), while 57.8% (52.6% and 63.5% in urban and rural areas) reported limitations in daily activities. Compared to urban residents, rural residents reported lower rates of dentist visits (p?=?0.006), specialist visits (p?=?0.028), faecal occult blood testing (p?<?0.001), colorectal cancer screening with colonoscopy (p?=?0.014), and breast cancer screening (p?=?0.035), and a higher rate of blood pressure measurement (p?=?0.042). Multivariable models indicated that urban residence was positively associated with faecal occult blood testing (OR?=?2.32, p?=?0.014), but negatively associated with blood pressure (OR?=?0.42, p?=?0.017) and blood glucose measurements (OR?=?0.48, p?=?0.009). These findings highlight the influence of residence on health service utilization among older adults in Hungary. Further comprehensive studies are needed to better understand the health needs of the elderly population and to develop policies aimed at promoting healthy aging in CEE countries.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Population ageing Preventive services Place of residence Central and Eastern Europe (CEE) Older adults
Megjelenés:	GeroScience. - 46 : 2 (2024), p. 2017-2031. -
További szerzők:	Pikó Péter (1987-) (biológus) Juhász Attila (1970-) (epidemiológus) Nagy Csilla (1970-) (epidemiológus, népegészségügyi szakember) Oroszi Beatrix (1970-) (orvos, epidemiológus) Ungvári Zoltán Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:	GINOP-2.3.2- 15-2016-00005 GINOP TK2016-78 Egyéb TKCS-2021/32 Egyéb 135784 OTKA ÚNKP-22-4-II-DE-268 Egyéb TKP2021-NKTA-47 Egyéb
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001-es BibID:	BIBFORM116680
035-os BibID:	(scopus)85170035800 (wos)001065103600003
Első szerző:	Pandics Tamás
Cím:	Exposome and unhealthy aging : environmental drivers from air pollution to occupational exposures / Pandics Tamas, Major David, Fazekas-Pongor Vince, Szarvas Zsofia, Peterfi Anna, Mukli Peter, Gulej Rafal, Ungvari Anna, Fekete Monika, Tompa Anna, Tarantini Stefano, Yabluchanskiy Andriy, Conley Shannon, Csiszar Anna, Tabak Adam G., Benyo Zoltan, Adany Roza, Ungvari Zoltan
Dátum:	2023
ISSN:	2509-2715 2509-2723
Megjegyzések:	The aging population worldwide is facing a significant increase in age-related non-communicable diseases, including cardiovascular and brain pathologies. This comprehensive review paper delves into the impact of the exposome, which encompasses the totality of environmental exposures, on unhealthy aging. It explores how environmental factors contribute to the acceleration of aging processes, increase biological age, and facilitate the development and progression of a wide range of age-associated diseases. The impact of environmental factors on cognitive health and the development of chronic age-related diseases affecting the cardiovascular system and central nervous system is discussed, with a specific focus on Alzheimer's disease, Parkinson's disease, stroke, small vessel disease, and vascular cognitive impairment (VCI). Aging is a major risk factor for these diseases. Their pathogenesis involves cellular and molecular mechanisms of aging such as increased oxidative stress, impaired mitochondrial function, DNA damage, and inflammation and is influenced by environmental factors. Environmental toxicants, including ambient particulate matter, pesticides, heavy metals, and organic solvents, have been identified as significant contributors to cardiovascular and brain aging disorders. These toxicants can inflict both macro- and microvascular damage and many of them can also cross the blood?brain barrier, inducing neurotoxic effects, neuroinflammation, and neuronal dysfunction. In conclusion, environmental factors play a critical role in modulating cardiovascular and brain aging. A deeper understanding of how environmental toxicants exacerbate aging processes and contribute to the pathogenesis of neurodegenerative diseases, VCI, and dementia is crucial for the development of preventive strategies and interventions to promote cardiovascular, cerebrovascular, and brain health. By mitigating exposure to harmful environmental factors and promoting healthy aging, we can strive to reduce the burden of age-related cardiovascular and brain pathologies in the aging population. ? 2023, The Author(s).
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Accelerated aging Aging Biological age Environmental pollution Exposome Toxicology
Megjelenés:	GeroScience. - 45 : 6 (2023), p. 3381-3408. -
További szerzők:	Major Dávid Fazekas-Pongor Vince Szarvas Zsófia Péterfi Anna Mukli Péter Gulej, Rafal Ungvári Anna Fekete Mónika Tompa Anna Tarantini, Stefano Yabluchanskiy, Andriy Conley, Shannon M. Csiszár Anna Tabák Ádám G. Benyó Zoltán Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) Ungvári Zoltán
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001-es BibID:	BIBFORM117425
035-os BibID:	(Scopus)85179338215 (WoS)001115572500001
Első szerző:	Ungvári Zoltán
Cím:	The Semmelweis Study : a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging / Zoltan Ungvari, Adam G. Tabák, Roza Adany, György Purebl, Csilla Kaposvári, Vince Fazekas-Pongor, Tamás Csípő, Zsófa Szarvas, Krisztián Horváth, Peter Mukli, Piroska Balog, Robert Bodizs, Peter Ujma, Adrienne Stauder, Daniel W. Belsky, Illés Kovács, Andriy Yabluchanskiy, Andrea B. Maier, Mariann Moizs, Piroska Östlin, Yongjie Yon, Péter Varga, Zoltán Vokó, Magor Papp, István Takács, Barna Vásárhelyi, Péter Torzsa, Péter Ferdinandy, Anna Csiszar, Zoltán Benyó, Attila J. Szabó, Gabriella Dörnyei, Mika Kivimäki, Miklos Kellermayer, Bela Merkely
Dátum:	2024
ISSN:	2509-2715 2509-2723
Megjegyzések:	The Semmelweis Study is a prospective occupational cohort study that seeks to enroll all employees of Semmelweis University (Budapest, Hungary) aged 25 years and older, with a population of 8866 people, 70.5% of whom are women. The study builds on the successful experiences of the Whitehall II study and aims to investigate the complex relationships between lifestyle, environmental, and occupational risk factors, and the development and progression of chronic age-associated diseases. An important goal of the Semmelweis Study is to identify groups of people who are aging unsuccessfully and therefore have an increased risk of developing age-associated diseases. To achieve this, the study takes a multidisciplinary approach, collecting economic, social, psychological, cognitive, health, and biological data. The Semmelweis Study comprises a baseline data collection with open healthcare data linkage, followed by repeated data collection waves every 5 years. Data are collected through computer-assisted self-completed questionnaires, followed by a physical health examination, physiological measurements, and the assessment of biomarkers. This article provides a comprehensive overview of the Semmelweis Study, including its origin, context, objectives, design, relevance, and expected contributions.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Age-associated diseases Biological age Central Europe Epidemiology Health Promoting University Healthy aging Workplace cohort
Megjelenés:	GeroScience. - 46 : 1 (2024), p. 191-218. -
További szerzők:	Tabák Ádám G. Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) Purebl György Kaposvári Csilla Fazekas-Pongor Vince Csípő Tamás (1990-) Szarvas Zsófia Horváth Krisztián Mukli Péter Balog Róbert Bódizs Róbert Ujma Péter Stauder Adrienne Belsky, Daniel W. Kovács Illés Yabluchanskiy, Andriy Maier, Andrea B. Moizs Marianna (1964-) (orvos) Östlin Piroska Yon, Yongjie Varga Péter Vokó Zoltán (1968-) (epidemiológus) Papp Magor Csongor (1978-) (háziorvostan szakorvos) Takács István Vásárhelyi Barna Torzsa Péter Ferdinándy Péter Csiszár Anna Benyó Zoltán Szabó Attila (gyermekgyógyász Budapest) Dörnyei Gabriella Kivimäki, Mika Kellermayer Miklós Merkely Béla (1965-) (orvos)
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