CCL

Összesen 7 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM105605
035-os BibID:(cikkazonosító)1226 (WoS)000912417100001 (Scopus)85149505856
Első szerző:Emri Tamás (biológus)
Cím:Stress Responses Elicited by Glucose Withdrawal in Aspergillus fumigatus / Tamás Emri, Károly Antal, Barnabás Gila, Andrea P. Jónás, István Pócsi
Dátum:2022
ISSN:2309-608X
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
aspergillus
fumigatus
stress
Megjelenés:Journal of Fungi. - 8 : 11 (2022), p. 1-19. -
További szerzők:Antal Károly Gila Csaba Barnabás (1994-) (biotechnológus, biomérnök) Jónás Andrea P. Pócsi István (1961-) (vegyész)
Pályázati támogatás:EFOP-3.6.1-16-2016-00022
EFOP
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM093928
035-os BibID:(cikkazonosító)341 (WoS)000654309100001 (Scopus)85105797365
Első szerző:Ezzat, Gaballa Kassem Ahmed (agrár)
Cím:Temporal Patterns and Inter-Correlations among Physical and Antioxidant Attributes and Enzyme Activities of Apricot Fruit Inoculated with Monilinia laxa under Salicylic Acid and Methyl Jasmonate Treatments under Shelf-Life Conditions / Ahmed Ezzat, Szilárd Szabó, Zoltán Szabó, Attila Hegedűs, Dorina Berényi, Imre J. Holb
Dátum:2021
ISSN:2309-608X
Megjegyzések:Monilinia laxa causes serious postharvest damage on apricot fruits under shelf-life storage conditions. Plant elicitors of methyl jasmonate (MeJA) and salicylic acid (SA) can reduce this damage, and their research can explain the background of the plant defense physiological processes in M. laxa-infected fruits. The aims of this study were: (i) to evaluate the effect of various concentrations of MeJA and SA on brown rot incidence (BRI) and lesion diameter (LD) of apricot fruits; (ii) to measure the temporal patterns for the effect of 0.4 mmol L?1 MeJA and 2 mmol L?1 SA treatments on BRI, LD and seven fruit measures (fruit firmness (FF), lignin content (LC), total soluble phenol content (TSPC), total antioxidant capacity (TAC) and enzyme activities of PAL, POD and SOD) in treatments of M. laxa-inoculated versus (vs.) non-inoculated fruits over an eight-day shelf-life storage period; and (iii) to determine inter-correlations among the seven fruit measures for MeJA and SA treatments. Both MeJA and SA significantly reduced BRI and LD. LC, FF, TAC, TSPC, as well as SOD and PAL activities in the MeJA and SA treatments were higher than the water-treated control in most assessment days and both inoculation treatments. In both inoculation treatments, the activity of POD in the SA-treated fruits was higher than MeJA-treated and control fruits at all dates. In MeJA vs. SA and inoculated vs. non-inoculated treatments, six variable pairs (FF vs. TSPC, FF vs. TAC, TAC vs. PAL, PAL vs. POD, PAL vs. SOD, and POD vs. SOD) showed significant inter-correlation values. Principal component analyses explained 96% and 93% of the total variance for inoculated and non-inoculated treatments, respectively. In inoculated treatments, both PC1 and PC2 explained 41% of the total variance and correlated with FF, TSPC and TAC and with PAL, SOD and POD, respectively. In non-inoculated treatments, PC1 and PC2 explained 49% and 44% of the total variance and correlated with LC, PAL, POD and SOD and with FF, TSPC and TAC, respectively. It can be concluded that MeJA and SA are useful in the practice to enhance the plant defense system against brown rot by reducing fungal growth and by improving physical and antioxidant attributes (FF, LC, TAC and TSPC) and the activity of defense-related enzymes (PAL, POD and SOD) in apricot fruits during shelf-life storage conditions.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
brown rot
lesion diameter
lignin
fruit firmness
phenol content
antioxidant capacity
defense related enzymes
Pearson correlation
regression analyses
PCA
Megjelenés:Journal of Fungi. - 7 : 5 (2021), p. 1-24. -
További szerzők:Szabó Szilárd (1974-) (geográfus) Szabó Zoltán (1960-) (kertészmérnök) Hegedűs Attila Berényi Dorina Holb Imre (1973-) (agrármérnök)
Pályázati támogatás:K 131478
OTKA
TÁMOP-4.2.4.A/2-11/1-2012-0001
TÁMOP
TKP2020-NKA-04
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM101910
035-os BibID:(cikkazonosító)397 (WoS)000787051700001 (Scopus)85129122957
Első szerző:Fekete Erzsébet (biotechnológus, egyetemi tanár)
Cím:Unique and Repeated Stwintrons (Spliceosomal Twin Introns) in the Hypoxylaceae / Erzsébet Fekete, Fruzsina Pénzes, Norbert Ág, Viktória Ág-Rácz, Erzsébet Sándor, Claudio Scazzocchio, Michel Flipphi, Levente Karaffa
Dátum:2022
ISSN:2309-608X
Megjegyzések:Introns are usually non-coding sequences interrupting open reading frames in pre-mRNAs [D1,2]. Stwintrons are nested spliceosomal introns, where an internal intron splits a second donor sequence into two consecutive splicing reactions leading to mature mRNA. In Hypoxylon sp. CO27-5, 36 highly sequence-similar [D1,2] stwintrons are extant (sister stwintrons). An additional 81 [D1,2] sequence-unrelated stwintrons are described here. Most of them are located at conserved gene positions rooted deep in the Hypoxylaceae. Absence of exonic sequence bias at the exon?stwintron junctions and a very similar phase distribution were noted for both groups. The presence of an underlying sequence symmetry in all 117 stwintrons was striking. This symmetry, more pronounced near the termini of most of the full-length sister stwintrons, may lead to a secondary structure that brings into close proximity the most distal splice sites, the donor of the internal and the acceptor of the external intron. The Hypoxylon stwintrons were overwhelmingly excised by consecutive splicing reactions precisely removing the whole intervening sequence, whereas one excision involving the distal splice sites led to a frameshift. Alternative (mis)splicing took place for both sister and uniquely occurring stwintrons. The extraordinary symmetry of the sister stwintrons thus seems dispensable for the infrequent, direct utilisation of the distal splice sites.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
spliceosomal introns
splicing; stwintrons
comparative genomics
stwintron dissemination
stwintron propagation
internal symmetry
single-stranded RNA secondary structure prediction
Hypoxylon sp. CO27-5
Hypoxylaceae
Megjelenés:Journal of Fungi. - 8 : 4 (2022), p. 1-23. -
További szerzők:Pénzes Fruzsina (1995-) (okleveles biomérnök) Ág Norbert (1987-) (okleveles biomérnök) Ág-Rácz Viktória (1991-) (mikrobiológus) Karaffa Erzsébet Mónika (1972-) (mikrobiológus, egyetemi tanár) Scazzocchio, Claudio Flipphi, Michel (1964-) Karaffa Levente (1971-) (biotechnológus, egyetemi tanár)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM117383
035-os BibID:(cikkazonosító)1195 (WoS)001132751600001 (Scopus)85180472702
Első szerző:Flipphi, Michel
Cím:Generation, Transfer, and Loss of Alternative Oxidase Paralogues in the Aspergillaceae Family / Michel Flipphi, Alexandra Márton, Vivien Bíró, Norbert Ág, Erzsébet Sándor, Erzsébet Fekete, Levente Karaffa
Dátum:2023
ISSN:2309-608X
Megjegyzések:Abstract: Alternative oxidase (Aox) is a terminal oxidase operating in branched electron transport. The activity correlates positively with overflow metabolisms in certain Aspergilli, converting intracellular glucose by the shortest possible path into organic acids, like citrate or itaconate. Aox is nearly ubiquitous in fungi, but aox gene multiplicity is rare. Nevertheless, within the family of the Aspergillaceae and among its various species of industrial relevance?Aspergillus niger, A. oryzae, A. terreus, Penicillium rubens?paralogous aox genes coexist. Paralogous genes generally arise from duplication and are inherited vertically. Here, we provide evidence of four independent duplication events along the lineage that resulted in aox paralogues (aoxB) in contemporary Aspergillus and Penicillium taxa. In some species, three aox genes are co-expressed. The origin of the A. niger paralogue is different than that of the A. terreus paralogue, but all paralogous clades ultimately arise from ubiquitous aoxA parent genes. We found different patterns of uncorrelated gene losses reflected in the Aspergillus pedigree, albeit the original aoxA orthologues persist everywhere and are never replaced. The loss of acquired paralogues co-determines the contemporary aox gene content of individual species. In Aspergillus calidoustus, the two more ancient paralogues have, in effect, been replaced by two aoxB genes of distinct origins.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Aspergillus
Penicillium
alternative oxidase
aox gene multiplicity
gene duplication
paralogous genes
gene loss
Megjelenés:Journal of Fungi. - 9 : 12 (2023), p. 1-18. -
További szerzők:Márton Alexandra (1994-) (mikrobiológus) Bíró Vivien (1994-)c(mikrobiológus) Ág Norbert (1987-) (okleveles biomérnök) Karaffa Erzsébet Mónika (1972-) (mikrobiológus, egyetemi tanár) Fekete Erzsébet (1975-) (biotechnológus, egyetemi tanár) Karaffa Levente (1971-) (biotechnológus, egyetemi tanár)
Pályázati támogatás:ÚNKP-23-3-II-DE-359
Egyéb
ÚNKP-23-4-IDE-362
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM111705
035-os BibID:(cikkazonosító)570 (Scopus)85160535117 (WoS)000997803000001
Első szerző:Flipphi, Michel
Cím:Mutations in the Second Alternative Oxidase Gene: A New Approach to Group Aspergillus niger Strains / Michel Flipphi, Alexandra Márton, Vivien Bíró, Norbert Ág, Erzsébet Sándor, Erzsébet Fekete, Levente Karaffa
Dátum:2023
ISSN:2309-608X
Megjegyzések:Alternative oxidase is a terminal oxidase in the branched mitochondrial electron transport chain of most fungi including Aspergillus niger (subgenus Circumdati, section Nigri). A second, paralogous aox gene (aoxB) is extant in some A. niger isolates but also present in two divergent species of the subgenus Nidulantes A. calidoustus and A. implicatus?as well as in Penicillium swiecickii. Black aspergilli are cosmopolitan opportunistic fungi that can cause diverse mycoses and acute aspergillosis in immunocompromised individuals. Amongst the approximately 75 genome-sequenced A. niger strains, aoxB features considerable sequence variation. Five mutations were identified that rationally affect transcription or function or terminally modify the gene product. One mutant allele that occurs in CBS 513.88 and A. niger neotype strain CBS 554.65 involves a chromosomal deletion that removes exon 1 and intron 1 from aoxB. Another aoxB allele results from retrotransposon integration. Three other alleles result from point mutations: a missense mutation of the start codon, a frameshift, and a nonsense mutation. A. niger strain ATCC 1015 has a full-length aoxB gene. The A. niger sensu stricto complex can thus be subdivided into six taxa according to extant aoxB allele, which may facilitate rapid and accurate identification of individual species
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
ubiquinol:oxygen oxidoreductase encoding gene
Aspergillus niger sensu stricto complex
alleles
chromosomal deletion
retrotransposon insertion
point mutation
frameshift mutation
nonsense mutation
molecular taxonomy
Megjelenés:Journal of Fungi. - 9 : 5 (2023), p. 1-17. -
További szerzők:Márton Alexandra (1994-) (mikrobiológus) Bíró Vivien (1994-)c(mikrobiológus) Ág Norbert (1987-) (okleveles biomérnök) Karaffa Erzsébet Mónika (1972-) (mikrobiológus, egyetemi tanár) Fekete Erzsébet (1975-) (biotechnológus, egyetemi tanár) Karaffa Levente (1971-) (biotechnológus, egyetemi tanár)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

6.

001-es BibID:BIBFORM103777
035-os BibID:(cikkazonosító)985 (WoS)000873175600001 (Scopus)85140589458
Első szerző:Máthéné Szigeti Zsuzsa (biológus-ökológus)
Cím:Potential Original Drug for Aspergillosis: In Vitro and In Vivo Effects of 1-N,N-Dimethylamino-5-Isocyanonaphthalene (DIMICAN) on Aspergillus fumigatus / Zsuzsa Máthéné Szigeti, László Tálas, Adrienn Széles, Zoltán Hargitai, Zsolt László Nagy, Miklós Nagy, Alexandra Kiss, Sándor Kéki, Gábor Szemán-Nagy
Dátum:2022
ISSN:2309-608X
Megjegyzések:As the recent outbreak of coronavirus disease 2019 (COVID-19) has shown, viral infections are prone to secondary complications like invasive aspergillosis with a high mortality rate, and therefore the development of novel, effective antifungals is of paramount importance. We have previously demonstrated that 1-amino-5-isocyanonaphthalene (ICAN) derivatives are promising original drug candidates against Candida strains (Patent pending), even against fluconazole resistant C. albicans. Consequently, in this study ICANs were tested on Aspergillus fumigatus, an opportunistic pathogen, which is the leading cause of invasive and systematic pulmonary aspergillosis in immunosuppressed, transplanted and cancer- or COVID-19 treated patients. We have tested several N-alkylated ICANs, a well as 1,5-naphthalene-diisocyanide (DIN) with the microdilution method against Aspergillus fumigatus strains. The results revealed that the diisocyanide (DIN) was the most effective with a minimum inhibitory concentration (MIC) value as low as 0.6 ?g mL?1 (3.4 ?M); however, its practical applicability is limited by its poor water solubility, which needs to be overcome by proper formulation. The other alkylated derivatives also have in vitro and in vivo anti-Aspergillus fumigatus effects. For animal experiments the second most effective derivative 1-N, N-dimethylamino-5-isocyanonaphthalene (DIMICAN, MIC: 7?8 ?g mL?1, 36?41 ?M) was selected, toxicity tests were made with mice, and then the antifungal effect of DIMICAN was tested in a neutropenic aspergillosis murine model. Compared to amphotericin B (AMB), a well-known antifungal, the antifungal effect of DIMICAN in vivo turned out to be much better (40% vs. 90% survival after eight days), indicating its potential as a clinical drug candidate.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
antifungal effect
drug
aspergillosis
isocyanide
murine model
Megjelenés:Journal of Fungi. - 8: 10 (2022), p. 1-11. -
További szerzők:Tálas László 1988-) (mikrobiológia) Széles Adrienn (1980-) (okleveles agrármérnök) Hargitai Zoltán Nagy Zsolt László (1989-) (gyógyszerész) Nagy Miklós Kiss Alexandra (1994-) (gyógyszer-biotechnológus) Kéki Sándor (1964-) (polimer kémikus) Szemán-Nagy Gábor (1975-) (biológia tanár-molekuláris biológus)
Pályázati támogatás:NKFIH-K-132685
Egyéb
TKP2020-IKA-04
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

7.

001-es BibID:BIBFORM102275
035-os BibID:(cikkazonosító)580 (WoS)000818193900001 (Scopus)85131598895
Első szerző:Molnár Bianka
Cím:Temporal Dynamics of Incidence of Shot Hole Disease Affected by Training Systems and Cultivar Susceptibilities in an Integrated Plum Orchard / Molnár Bianka, Szabó Szilárd, Holb Imre J.
Dátum:2022
ISSN:2309-608X
Megjegyzések:Shot hole disease (SHD) can cause severe epidemics in plum orchards, depending on cultivar susceptibility and training system; however, the combined effect on the progress of temporal disease and on the possible reduction in SHD in the disease management was not investigated. The aim of this 3-year study was (i) to monitor and analyze the temporal dynamics of SHD progress under four training systems (4 ? 1.5, 4 ? 2, 5 ? 2.5 and 6 ? 3 m) and on four plum cultivars (♭?Ca?canska lepotica', ♭Bluefre', ♭Stanley' and ♭President') in an integrated plum orchard; (ii) to identify those time periods when training system and cultivar combinations can reduce the disease development. Both SHD incidences and the area under the disease progress curves (AUDPC) were significantly affected by the training system, cultivar and year. Plum cultivars with high or mid?high susceptibility to SHD showed continuous SHD development from May to November, while cultivars with low susceptibility to SHD showed no symptoms until mid-summer and then progressed slowly until November. High (4 ? 1.5 m) vs. low (6 ? 3 m) density training systems reduced SHD incidence and AUDPC consistently for three cultivars (♭?Ca?canska lepotica', ♭Stanley' and ♭President') in September, October and November, compared to the high-density training system. Only cv. ♭Bluefre' showed no effect either on disease incidence or AUDPC, due to very high disease incidences in all training systems from September to November. In conclusions, combinations of training system and cultivar can significantly reduce SHD incidence, which may be successfully used as a part of the integrated pest management approach during the establishment new plantations.
Tárgyszavak:Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
shot hole
Stigmina carpophila
Wilsonomyces carpophilus
training system
cultivar susceptibility
plum cultivar
disease incidence
AUDPC
temporal dynamics
Megjelenés:Journal of Fungi. - 8 : 6 (2022), p. 1-18. -
További szerzők:Szabó Szilárd (1974-) (geográfus) Holb Imre (1973-) (agrármérnök)
Pályázati támogatás:K 131478
OTKA
TÁMOP-4.2.4.A/2-11/1-2012-0001
TÁMOP
A2-SZJ-TOK-13-0061
Egyéb
TKP2020-NKA-04
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1 
Corvina könyvtári katalógus v8.2.27 © 2023 Monguz kft. Minden jog fenntartva.