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001-es BibID:	BIBFORM105481
035-os BibID:	(Scopus)85060597443 (WOS)000462037300002
Első szerző:	Hoenink, Jody C.
Cím:	The Moderating Role of Social Neighbourhood Factors in the Association between Features of the Physical Neighbourhood Environment and Weight Status / Jody C. Hoenink, Jeroen Lakerveld, Harry Rutter, Sofie Compernolle, Ilse De Bourdeaudhuij, Helga Bárdos, Helene Charreire, Jean Michel Oppert, Joreintje D. Mackenbach
Dátum:	2019
ISSN:	1662-4025 1662-4033
Megjegyzések:	Background: This paper investigated the independent and joint associations between aspects of the physical neighbourhood environment and social neighbourhood factors with BMI and overweight status in European adults. Methods: Data from 5,199 participants in the SPOTLIGHT survey were analysed. Participants reported on their height, weight and perceptions of the neighbourhood. Objectively measured aspects of the physical neighbourhood environment included: presence of recreational facilities, features of the active transportation environment, neighbourhood aesthetics and presence of different types of food outlets. Social factors included the self-reported variables social network, social cohesion, social trust and perceived crime and the census variable neighbourhood socioeconomic status. Outcome measures were BMI and overweight status. Main associations between physical and social factors and BMI/overweight status were analysed using multilevel regression analyses adjusted for confounders. Moderation analysis was conducted by adding the interaction terms between physical and social neighbourhood factors one by one to the multivariable models. Significant interaction terms were then stratified. Results: Significant associations with BMI/overweight status were found for features of the active transportation environment and all social factors, except perceived crime. Several significant interaction terms were detected, but no significant associations between the physical neighbourhood environment and BMI/overweight status were found after stratification. Conclusion: We did not find consistent interactions between physical and social neighbourhood factors to explain BMI and overweight status.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Socio-ecological model Weight status Physical environment Social factors Adults
Megjelenés:	Obesity Facts. - 12 : 1 (2019), p. 14-24. -
További szerzők:	Lakerveld, Jeroen Rutter, Harry Compernolle, Sofie De Bourdeaudhuij, Ilse Bárdos Helga (1969-) (megelőző orvostan és népegészségtan szakorvos) Charreire, Hélène Oppert, Jean-Michel Mackenbach, Joreintje Dingena
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001-es BibID:	BIBFORM069536
Első szerző:	Nagy Károly (népegészségügyi felügyelő)
Cím:	Distinct penetrance of obesity associated susceptibility alleles in the Hungarian general and Roma populations / Nagy Károly, Fiatal Szilvia, Sándor János, Ádány Róza
Dátum:	2017
ISSN:	1662-4025 1662-4033
Megjegyzések:	Methods: A total of 1152 samples from the Hungarian Roma population and 1743samples from the Hungarian general population were genotyped for 20 single nucleotidepolymorphisms (SNPs) associated with the risk of obesity. Two types of multilocusgenetic risk scores were constructed to estimate the combined effect of selected SNPs.Results: Risk allele frequencies differed significantly between the two populations for11 SNPs, with no enrichment in any of the two study groups. Variants (rs1558902,rs1121980, rs9939609 and rs9941349) in the fat mass and obesity-associated (FTO)gene exhibited strong but ethnicity-independent association with obesity. Genetic risk scores showed stronger associations with obesity in the Roma population comparedwith the Hungarian general population; however, without significant gene-populationinteraction.Conclusion: Differences in obesity prevalence between the Hungarian general andHungarian Roma populations could not be explained by their distinct geneticsusceptibility, rather by ethnicity-related environmental and behavioural factors.Nonetheless, particular gene-environment interactions might contribute to the distinctpenetrance of the obesity-associated genetic factors in populations of different ethnicbackgrounds.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban body mass index FTO gene variants obesity Roma Gypsy genetic risk score
Megjelenés:	Obesity Facts. - 10 : 5 (2017), p. 444-457. -
További szerzők:	Fiatal Szilvia (1978-) (epidemiológus, népegészségügyi szakember) Sándor János (1966-) (orvos-epidemiológus) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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