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1.

001-es BibID:BIBFORM067720
Első szerző:Acciarresi, Monica
Cím:Prestroke CHA2DS2-VASc Score and Severity of Acute Stroke in Patients with Atrial Fibrillation : findings from RAF Study / Monica Acciarresi, Maurizio Paciaroni, Giancarlo Agnelli, Nicola Falocci, Valeria Caso, Cecilia Becattini, Simona Marcheselli, Christina Rueckert, Alessandro Pezzini, Andrea Morotti, Paolo Costa, Alessandro Padovani, Laszló Csiba, Lilla Szabó, Sung-Il Sohn, Tiziana Tassinari, Azmil H. Abdul-Rahim, Patrik Michel, Maria Cordier, Peter Vanacker, Suzette Remillard, Andrea Alberti, Michele Venti, Cataldo D'Amore, Umberto Scoditti, Licia Denti, Giovanni Orlandi, Alberto Chiti, Gino Gialdini, Paolo Bovi, Monica Carletti, Alberto Rigatelli, Jukka Putaala, Turgut Tatlisumak, Luca Masotti, Gianni Lorenzini, Rossana Tassi, Francesca Guideri, Giuseppe Martini, Georgios Tsivgoulis, Kostantinos Vadikolias, Chrissoula Liantinioti, Francesco Corea, Massimo Del Sette, Walter Ageno, Maria Luisa De Lodovici, Giorgio Bono, Antonio Baldi, Sebastiano D'Anna, Simona Sacco, Antonio Carolei, Cindy Tiseo, Davide Imberti, Dorjan Zabzuni, Boris Doronin, Vera Volodina, Domenico Consoli, Franco Galati, Alessio Pieroni, Danilo Toni, Serena Monaco, Mario Maimone Baronello, Kristian Barlinn, Lars-Peder Pallesen, Jessica Kepplinger, Ulf Bodechtel, Johannes Gerber, Dirk Deleu, Gayane Melikyan, Faisal Ibrahim, Naveed Akhtar, Maria Giulia Mosconi, Kennedy R. Lees
Dátum:2017
ISSN:1052-3057 1532-8511
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of stroke & cerebrovascular diseases 26 : 6 (2017), p. 1363-1368. -
További szerzők:Paciaroni, Maurizio Agnelli, Giancarlo Falocci, Nicola Caso, Valeria Becattini, Cecilia Marcheselli, Simona Rueckert, Christina Pezzini, Alessandro Morotti, Andrea Costa, Paolo Padovani, Alessandro Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Sohn, Sung-Il Tassinari, Tiziana Abdul-Rahim, Azmil H. Michel, Patrik Cordier, Maria Vanacker, Peter Remillard, Suzette Alberti, Andrea Venti, Michele D'Amore, Cataldo Scoditti, Umberto Denti, Licia Orlandi, Giovanni Chiti, Alberto Gialdini, Gino Bovi, Paolo Carletti, Monica Rigatelli, Alberto Putaala, Jukka Tatlisumak, Turgut Masotti, Luca Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Martini, Giuseppe Tsivgoulis, Georgios Vadikolias, Kostantinos Liantinioti, Chrissoula Corea, Francesco Del Sette, Massimo Ageno, Walter De Lodovici, Maria Luisa Bono, Giorgio Baldi, Antonio D'Anna, Sebastiano Sacco, Simona Carolei, Antonio Tiseo, Cindy Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Consoli, Domenico Galati, Franco Pieroni, Alessio Toni, Danilo Monaco, Serena Baronello, Mario Maimone Barlinn, Kristian Pallesen, Lars-Peder Kepplinger, Jessica Bodechtel, Ulf Gerber, Johannes Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Mosconi, Maria Giulia Lees, Kennedy R.
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2.

001-es BibID:BIBFORM029949
Első szerző:Bereczki Dániel (neurológus)
Cím:Stroke Units in Hungary : The Debrecen Experience / Bereczki D., Csiba L., Fülesdi B., Fekete I.
Dátum:2003
ISSN:1015-9770
Megjegyzések:The Debrecen Stroke Unit covers a catchment area of 210,000 inhabitants in eastern Hungary. The unit was established at the Department of Neurology of the University Hospital in 1974 and has 23 beds, 7 of which have monitoring facilities. The unit treats about 600 patients with acute cerebrovascular diseases annually - about 60% of all hospitalised stroke cases in the region. Overall, 18 registered nurses and 4 nurse helpers work for the unit. Computer tomography is performed in over 90% of cases. Carotid duplex ultrasound and echocardiography are part of the routine examinations in ischaemic strokes. Delay from onset of stroke to hospital arrival is the main barrier against the use of rt-PA. Average length of stay is 12 days; a lack of rehabilitation and nursing capacities sometimes delays discharge of dependent patients. The hospital is reimbursed the costs of stroke care based on DRG.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cerebrovascular Diseases. - 15 : Suppl. 1 (2003), p. 23-25. -
További szerzők:Csiba László (1952-) (neurológus, pszichiáter) Fülesdi Béla (1961-) (aneszteziológus) Fekete István (1951-) (neurológus, pszichiáter)
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3.

001-es BibID:BIBFORM029943
Első szerző:Bessenyei Mónika (neurológus, csecsemő- és gyermekgyógyász)
Cím:Characteristics of 4 stroke scales for the detection of changes in clinical signs in the acute phase of stroke / Bessenyei, M., Fekete, I., Csiba, L., Bereczki, D.
Dátum:2001
ISSN:1052-3057
Megjegyzések:OBJECTIVES: Detection of minor changes in clinical signs of stroke may be of interest when evaluating treatment interventions. This study analyzes the internal structure of four frequently used stroke scales and compares them for their sensitivity to detect changes in neurologic signs in the first week after acute stroke.METHODS:A cohort of 77 hospitalized acute stroke patients was scored by the Mathew, the National Institutes of Health (NIH), the Scandinavian, and the Orgogozo scales within 48 hours of hospital admission and again 7 days later.RESULTS:Scores on different scales correlated well with each other (range of absolute value of Spearman R, .82-.91; P <.001 in all comparisons). Scales reflected significant changes from entry to reexamination: P = .0013 for the Scandinavian scale (P = .004 for prognostic and P = .009 for long-term items, respectively); P = .00009 for the Orgogozo scale; P = .000007 for the Mathew scale; and P < .000001 for the NIH scale. This difference in sensitivity coincided with the number of factors extracted by principal component analysis: higher sensitivity of a scale was associated with a larger number of factors. Initial scores differed significantly among patients who were discharged, patients who died, and patients who remained hospitalized 7 days after the first examination (Kruskal-Wallis ANOVA, P < .01 for all scales).CONCLUSIONS:There are considerable differences in the internal structure of the different scales as reflected by the different number of factors extracted from the scale items. The application of the NIH scale is recommended for the most sensitive detection of changes in stroke signs.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 10 : 2 (2001), p. 70-78. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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4.

001-es BibID:BIBFORM045970
Első szerző:Bogousslavsky, Julien
Cím:The Mannheim Declaration of Stroke in Eastern Europe : accepted at the 13th European Stroke Conference, Mannheim-Heidelberg, Germany, May 12-15, 2004 / J. Bogousslavsky, M. G. Hennerici, M. Kaste, L. Csiba, M. Brainin, D. Bereczki, Z. Nagy, A. Czlonkowska, V. Demarin, J. Pascu, V. I. Skvortsova, E. Ehler
Dátum:2004
ISSN:1015-9770
Tárgyszavak:Orvostudományok Klinikai orvostudományok szerkesztőségi anyag
Megjelenés:Cerebrovascular Diseases. - 18 : 3 (2004), p. 248-248. -
További szerzők:Hennerici, M. Kaste, M. Csiba László (1952-) (neurológus, pszichiáter) Brainin, Michael Bereczki Dániel (1960-) (neurológus) Nagy Zoltán (1942-) (neurológus) Czlonkowska, A. Demarin, Vida Pascu, J. Skvortsova, Veronica I. Ehler, E.
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5.

001-es BibID:BIBFORM029302
Első szerző:Diener, Hans-Christoph
Cím:Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH) : study design and baseline data / Diener, H. C., Bogousslavsky, J., Brass, L. M., Cimminiello, C., Csiba, L., Kaste, M., Leys, D., Matias Guiu, J., Rupprecht, H. J., the MATCH Investigators
Dátum:2004
ISSN:1015-9770
Megjegyzések:The CAPRIE study showed the superiority of clopidogrel over acetylsalicylic acid (ASA) for reducing the combined risk of major atherothrombotic events in patients with recent myocardial infarction (MI), recent ischaemic stroke (IS) or established peripheral arterial disease. The benefit of clopidogrel over ASA is amplified in high-risk patients. Proof of concept for the benefit of clopidogrel in addition to ASA in patients with coronary manifestations of atherothrombosis was provided by the CURE trial. METHODS: MATCH is a randomized, double-blind, placebo-controlled trial that compares clopidogrel and ASA versus clopidogrel alone in high-risk patients with recently symptomatic cerebrovascular disease. Eligible patients have experienced a transient ischaemic attack (TIA) or IS within the last 3 months and have evidence of at least 1 additional risk factor within the last 3 years (prior IS, MI, stable or unstable angina pectoris, diabetes or symptomatic peripheral arterial disease). Patients were randomized to receive ASA 75 mg once daily or placebo, with both groups receiving clopidogrel 75 mg once daily as part of standard therapy. The primary end point is the composite of IS, MI, vascular death and rehospitalization for an acute ischaemic event. The duration of treatment and follow-up is 18 months for each patient. RESULTS: Enrollment was completed in April 2002, with 7,599 patients randomized to receive the study medication. The mean age at randomization was 66 years, and the qualifying event was IS in 78.9% of patients and TIA in 21.1%. The baseline features of the study cohort indicate a population that is at a high risk for atherothrombotic recurrence. CONCLUSION: MATCH is a major ongoing trial that will provide important data on the benefit of clopidogrel and ASA compared with clopidogrel alone for reduction of vascular ischaemic events in patients with recent TIA or IS who are at high risk of atherothrombotic event recurrence.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cerebrovascular Diseases. - 17 : 2-3 (2004), p. 253-261. -
További szerzők:Bogousslavsky, Julien Brass, Lawrence M. Cimminiello, Claudio Csiba László (1952-) (neurológus, pszichiáter) Kaste, Markku Leys, Didier Matias-Guiu, Jordi Rupprecht, Hans-Jürgen the MATCH Investigators
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6.

001-es BibID:BIBFORM079831
Első szerző:Fekete István (neurológus, pszichiáter)
Cím:Effect of acute stroke on heart function / I. Fekete, N. Deregi, J. Aranyosi, K. Fekete, L. Csiba
Dátum:2010
Megjegyzések:Background: There are contradictory data on how brain hemispheric localization/side influences the function of the heart. Our aim was to study the pathologic cardiological abnormalities in acute stroke patients without coronary heart disease or rhythm disturbances in the anamnesis. Methods: Between 1st of March, 2009 and 30th of September, 2009 at the Neurointensive Care Unit we monitorized 91 acute stroke patients' parameters continuously for 24-36 hours: pulse, systolic, diastolic, mean blood pressure, 12 lead ECG. We were interested in the correlation of the above mentioned parameters and age, side and size of the cerebral lesion (by CT/MRI), type of stroke, mortality. Exclusion criteria were: fever, severe hyperglycemia, cardiac failure, myocardial infarct, pulmonary disorders, obstructive sleep apnoe, drug or metabolic caused rhythm disturbances, beta blocker usage. Results: The average age was 62,3?14,6 years. The left hemisphere was affected in 45%, the right in 38,5%, both hemispheres in 3,3%, and 13,2% suffered from VB syndrome. Ischemic stroke was in 74,7%, hemorrhage 14,3%, SAH 3,3%, TIA 7,7%. In the group where no heart disorder was known at admission, altogether 18% had repolarization abnormalities (10 patients had ST depression, 7 ST elevation). In addition, especially during the night, by 33% of the patients supraventricular (SVES) and ventricular extrasystoles (VES) were detected. 35% of patients had tachycardy and 23% bradycardy, both were significantly higher in the right sided lesions (p<0.05). VES was more frequent in left hemispherical lesions and VB syndrome (p<0.05). Less than 90 mmHg systolic pressure could be detected in 27% of patients, this was remarkable at dawn. Nine patients died, in 2 patients fatal rhythm disturbance caused death. Conclusion: Both sided hemispheric lesions and VB syndromes can cause cardiological and ECG abnormalities. Intensive monitoring is essential in acute stroke at least for 36 hours.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Megjelenés:Cerebrovascular Diseases. - 29 : Suppl. 2 (2010), p. 157. -
További szerzők:Deregi N. Aranyosi János (1963-) (szülész-nőgyógyász) ifj. Fekete Klára (1978-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter)
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7.

001-es BibID:BIBFORM079825
Első szerző:Fekete Klára (neurológus)
Cím:Experiences with intravenous (IV) and intraarterial (IA) thrombolysis in Debrecen, Hungary, focused on glucose level at admission and patients over 80 / K. Fekete, D. Bereczki, L. Csiba, I. Fekete
Dátum:2010
ISSN:1015-9770
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:Cerebrovascular Diseases. - 29 : 2 (2010), p. 1-361. -
További szerzők:Bereczki Dániel (1960-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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8.

001-es BibID:BIBFORM079826
Első szerző:Fekete Klára (neurológus)
Cím:Alcohol consumption and smoking are associated with higher 30-day case fatality after stroke in the mures-uzhgorod-debrecen (mud) database / K. E. Fekete, S. Szatmári, I. Szőcs, C. Szekeres, J. Szász, L. Mihálka, V. Smolanka, L. Csiba, D. Bereczki
Dátum:2008
ISSN:1015-9770
Megjegyzések:Abstract Introduction: Age, alcohol consumption, smoking are important risk factors of stroke. After stroke most of the patients suffer from different grade of disability. Methods: In this work the risk factors, mentioned above, the disability and the 30 day case fatality was investigated by analyzing the data of 1047 patients from the MUD database between the 1 st of October 1999 and 30th of September 2000. (The distribution of the patients in the database is the following: 554 patients in Debrecen, 260 patients in Targu Mures and 233 in Uzhgorod). Results: The distribution of stroke concerning the genders by our database is the following: 42,5% female, 57,5 % male. Before discharge 222 patients (22,1%) died. By 172 of the patients (16,4%) occurred stroke in the familial-history. The ratio of the age was found more unfavorable by males: between 30 and 60 years the frequency of stroke was twice as high as by females (on the average by 30,75% of women and 69,26% of men suffer stroke).The ratio is very similar by cerebral bleeding not only ischemia. 249 of total stroke patients admitted alcohol consumption (23,8%), 551 did not (52,6%) (28,6%is unknown). The 30 day mortality rate was 25,3% between the patients admitting alcohol consumption, and only 9,3% between those who did not. In total 339 patients suffered cerebral bleeding ( 32,4%), which is higher then the literary dates. No difference was found between the 3 examination places. The ratio of death in the group of alcohol consumers and alcohol-non-consumer was equally prominently high without any difference. In our database 25,09% of the patients smoked. The excess of disability at dismission was analyzed by 825 patients with the following results: 153 patients (18,5%) needed permanent care, 182 (22%) patients needed help by every-day-life, 230 (27,5%) patients could live a self-sufficient life with residual signs, and 260 (31,5%) had no neurological sign. Results and conclusion: The analysis of the MUD database emphasizes the medical education of the population in health policy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:Cerebrovascular Diseases. - 25 : 2 (2008), p. 71. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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9.

001-es BibID:BIBFORM069439
Első szerző:Fekete Klára (neurológus)
Cím:Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database / Klára Fekete, Sándor Márton, László Csiba, István Fekete
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 26 : 1 (2017), p. 132-138. -
További szerzők:Márton Sándor (szociológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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10.

001-es BibID:BIBFORM062617
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database / Klára Fekete, Sándor Márton, Judit Tóth, László Csiba, István Fekete, Dániel Bereczki
Dátum:2015
ISSN:1052-3057 1532-8511
Megjegyzések:Background: This prospective single-center study aimed to identify features determininglong-term outcome after thrombolysis in a Central European stroke population.Methods: Between 1 January, 2004, and 31 December, 2010, 415 patients weretreated with recombinant tissue plasminogen activator at the Department ofNeurology, University of Debrecen. Stroke severity by the National Institute ofHealth Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke ProgrammeEarly Computed Tomography score (ASPECTS) were evaluated on admissionand 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatalityat 1 year were evaluated. Independent predictors of outcome were identified bymultivariate testing. Results: Data of 369 patients were analyzed. Median NIHSSSwas 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours.Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH)was detected in 3.8%. Outcome was significantly worse, and SICH was morefrequent in intra-arterially treated patients. At 3 months, one third of the patientswere independent (mRS #2), and 23% were dead. At 1 year 2 of 3 patients were alive.Significant independent predictors of disability at 3 months were 24-hour NIHSSS,admission ASPECTS, admission glucose level, and treatment modality. Only the24-hour NIHSSS was a significant predictor of case fatality at 1 year. Conclusions:Although short-term outcome was similar, the 3-month and 1-year outcomes wereworse than data from previous reports. A more efficient health care program shouldbe implemented after stroke to maintain the favorable effect of thrombolysis in thelong term.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Ischemic stroke
thrombolysis
predictors
outcome
Megjelenés:Journal Of Stroke And Cerebrovascular Diseases. - 24 : 1 (2015), p. 117-124. -
További szerzők:Márton Sándor (szociológus) Tóth Judit Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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11.

001-es BibID:BIBFORM049525
Első szerző:Fekete Klára (neurológus)
Cím:Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality / Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki
Dátum:2014
Megjegyzések:Background: Heavy alcohol consumption and smoking are known risk factors for stroke but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. Methods: Initial stroke severity was scored by the NIH stroke scale. Case fatality and the modified outcome scale of the 1st International Stroke Trial were used to assess outcome. We used multiple regression analysis.Results: Before their stroke, 24.5% were smokers and 24.7 % admitted regular alcohol consumption. Neither smoking nor alcohol consumption status were associated with initial stroke severity. Case fatality at discharge, at 30 days and at 1 year were 12.2%, 16.9% and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and non-consumers in 30-day and in one year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a non-significant tendency for higher case fatality among alcohol-consumers (39.5% vs. 26.4%, p>0.2 at 30 days and 48.8% vs. 35.8%, p>0.2 at 1 year). Smoking did not influence significantly the outcome at 30-days and at one-year.Conclusion: despite being risk factors, pre-stroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long- term outcome.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alcohol, smoking and stroke severity
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 23 : 1 (2014), p. e31-e37. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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12.

001-es BibID:BIBFORM004806
Első szerző:Harangi Mariann (belgyógyász, endokrinológus)
Cím:Association between human paraoxonase 1 activity and intima-media thickness in subjects under 55 years of age with carotid artery disease / Mariann Harangi, Ildiko Seres, Maria T. Magyar, Istvan Csipo, Sandor Sipka, Attila Valikovics, Laszlo Csiba, Daniel Bereczki, Gyorgy Paragh
Dátum:2008
Megjegyzések:Human serum paraoxonase (PON1) protects lipoproteins against oxidation by hydrolyzing lipid peroxides in oxidized low-density lipoprotein (oxLDL); therefore, it may protect against atherosclerosis. PON1 activity and polymorphisms have been inconsistently associated with carotid artery disease. The goal of this study was to clarify the role of PON1 activity and phenotype on carotid artery disease and its correlation with some inflammatory and immune markers in subjects under 55 years with early-onset carotid atherosclerosis. Methods: Sixty patients with occlusive carotid artery disease and 30 healthy controls were enrolled. Intimamedia thickness (IMT) was measured by high-resolution ultrasound of both common carotid arteries. Anti-oxLDL antibody levels were determined by ELISA. Results: In the whole study population we found a negative correlation between PON1 activity and IMT (r = -0.27, p = 0.011), and between saltstimulated PON1 activity and IMT (r = -0.24, p = 0.02). Both PON1 activity and salt-stimulated PON1 activity negatively correlated with anti-oxLDL levels (r = -0.28, p = 0.008; r = -0.26, p = 0.01). PON1 activity was lower in patients compared to controls; however, the difference was not significant.PON1 phenotype distribution of patients and controls did not differ significantly. Conclusion: The importance of PON1 activity as a redictive risk factor for early-onset occlusive carotid artery disease should be assessed in future studies.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Paraoxonase
Intima-media thickness
egyetemen (Magyarországon) készült közlemény
Megjelenés:Cerebrovascular Diseases 25 : 1-2 (2008), p. 122-128. -
További szerzők:Seres Ildikó (1954-) (biokémikus) Magyar Mária Tünde (1970-) (neurológus) Csípő István (1953-) (vegyész) Sipka Sándor (1945-) (laboratóriumi szakorvos) Valikovics Attila Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus) Paragh György (1953-) (belgyógyász)
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