CCL

Összesen 10 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM042976
Első szerző:Alafuzoff, Irina
Cím:The need to unify neuropathological assessments of vascular alterations in the ageing brain : multicentre survey by the BrainNet Europe consortium / Irina Alafuzoff, Ellen Gelpi, Safa Al-Sarraj, Thomas Arzberger, Johannes Attems, Istvan Bodi, Nenad Bogdanovic, Herbert Budka, Orso Bugiani, Elisabet Englund, Isidro Ferrer, Stephen Gentleman, Giorgio Giaccone, Manuel B. Graeber, Tibor Hortobagyi, Romana Höftberger, James W. Ironside, Kurt Jellinger, Nikolaos Kavantzas, Andrew King, Penelope Korkolopoulou, Gábor G. Kovács, David Meyronet, Camelia Monoranu, Piero Parchi, Efstratios Patsouris, Wolfgang Roggendorf, Annemieke Rozemuller, Danielle Seilhean, Nathalie Streichenberger, Dietmar R. Thal, Stephen B. Wharton, Hans Kretzschmar
Dátum:2012
ISSN:0531-5565
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Experimental Gerontology. - 47 : 11 (2012), p. 825-833. -
További szerzők:Gelpi, Ellen Al-Sarraj, Safa Arzberger, Thomas Attems, Johannes Bódi István (1967-) (neuropatológus) Bogdanovic, Nenad Budka, Herbert Bugiani, Orso Englund, Elisabet Ferrer, Isidro Gentleman, Stephen Giaccone, Giorgio Graeber, Manuel Hortobágyi Tibor (1965-) (patológus) Höftberger, Romana Ironside, James W. Jellinger, Kurt Kavantzas, Nikolaos King, Andrew Korkolopoulou, Penelope Kovács Gábor Géza (1969-) (neurológus) Meyronet, David Monoranu, Camelia Parchi, Piero Patsouris, Efstratios Roggendorf, Wolfgang Rozemuller, Annemieke Seilhean, Danielle Streichenberger, Nathalie Thal, Dietmar R. Wharton, Stephen B. Kretzschmar, Hans
Internet cím:DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM046087
Első szerző:Damjanovich Sándor (biofizikus)
Cím:Signal transduction in T lymphocytes and aging / Damjanovich S., Gaspar R., Bene L., Jenei A., Matyus L.
Dátum:2003
ISSN:0531-5565
Megjegyzések:Subclasses of cells in different compartments of the immune system possesses all those attributes, that make them suitable though somewhat limited models for the investigation of cellular processes during aging. Blood samples provide relative easily high amount of cells belonging to the same subclass, all of them having complex cascade processes in their signal transduction mechanisms, therefore being excellent targets for such investigations. One such subclass comprises peripheral blood lymphocytes. The signal-transduction cascade across the plasma membrane of lymphocytes displays many of the general features enabling us to draw conclusions for other cellular signaling problems that may arise during aging in other cell types not directly related to the immune system. The advantage of this approach lies in the fact that sometimes it is extremely difficult to study signal transduction processes in certain cell types under physiological conditions. The simultaneous occurrence of physical, chemical and molecular biological regulation of the immune processes at cellular and network levels make them very good examples for focusing our interest also on similar processes in other systems and cells. The fast developing new measuring techniques and the rapidly accumulating experimental data make it relatively easy to provide interesting new aspects, and ideas in this field. Finally, the immune system itself has its great importance and after all, it has an obvious declination with aging, the immune-senescence.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Experimental Gerontology. - 38 : 3 (2003), p. 231-236. -
További szerzők:Gáspár Rezső (1944-) (biofizikus) Bene László (1963-) (biofizikus) Jenei Attila (1966-) (biofizikus) Mátyus László (1956-) (biofizikus)
Pályázati támogatás:T029947
OTKA
T030411
OTKA
F034487
OTKA
TS040773
OTKA
T42618
OTKA
T43087
OTKA
T43509
OTKA
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM004679
Első szerző:Damjanovich Sándor (biofizikus)
Cím:Experimental gerontology in Hungary / Damjanovich, S., Zs. Nagy, I., Gaspar, R.
Dátum:2001
Megjegyzések:Gerontological research has some past and sporadically also some highlights in Hungary, but its present state can be easily deduced from the following data. During the last 12 years and more, well over 10,000 Hungarian scientific papers have been published in well-recognized national or international journals. Altogether approximately 1% of them have been classified as gerontological publications from Hungary. This low figure shows that gerontology has low priority and--unfortunately low support--in Hungary. This statement does not intend to downgrade Hungarian gerontologists, however points out that the Hungarian trends are not far from those of European or world wide interest in aging. Despite the recognition that we have to accept the inevitable fact that industrial societies will have (they already have) an aging population with all the social and medical problems arising, the focus of interest is wide from this significant and interesting (sub)population, which is neglected (sometimes even despised); yet everybody is absolutely eager to join this club. The average of the Hungarian research achievements and publication activities are among the better European achievements. There are some highlights and new trends even initiated by some outstanding Hungarian scientists, yet the overall weight of gerontology research is still an orphan in the Hungarian scientific life. We deal in this short and far from complete summary almost exclusively with experimental gerontology. We have to apologize if we have not included everybody, who also contributed even significantly to this field because the time for the preparation of this overview was short.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Aging
Animal
Geriatrics
Human
Hungary
Research
trends
Megjelenés:Experimental Gerontology. - 37 : 1 (2001), p. 9-17. -
További szerzők:Zs. Nagy Imre Gáspár Rezső (1944-) (biofizikus)
Internet cím:elektronikus változat
DOI
Borító:

4.

001-es BibID:BIBFORM076740
035-os BibID:(WoS)000462601700002 (Scopus)85062950434
Első szerző:Fülöp Gábor Áron (általános orvos)
Cím:IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries : a Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging / Fulop Gabor A., Ramirez-Perez Francisco I., Kiss Tamas, Tarantini Stefano, Valcarcel Ares Marta Noa, Toth Peter, Yabluchanskiy Andriy, Conley Shannon M., Ballabh Praveen, Martinez-Lemus Luis A., Ungvari Zoltan, Csiszar Anna
Dátum:2019
ISSN:1079-5006
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journals Of Gerontology Series A-Biological Sciences And Medical Sciences. - 74 : 4 (2019), p. 446-454. -
További szerzők:Ramirez-Perez, Francisco I. Kiss Tamás Tarantini, Stefano Valcarcel Ares, Marta Noa Tóth Péter (sebész) Yabluchanskiy, Andriy Conley, Shannon M. Ballabh, Praveen Martinez-Lemus, Luis A. Ungvári Zoltán Csiszár Anna
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM017665
Első szerző:Seres Ildikó (biokémikus)
Cím:Study of factors influencing the decreased HDL associated PON1 activity with aging / Seres Ildikó, Paragh György, Deschene Elaine, Fülöp Tamás, Khalil Abdelouahed
Dátum:2004
ISSN:0531-5565
Megjegyzések:Paraoxonase (PON1) is principally complexed to HDL and is responsible, at least in part, for its antioxidant properties. PON1 activity decreases in several pathologies associated with atherosclerosis. The aim of this study was to investigate the PON1 activity and factors influencing its activity as a function of age. One hundred and twenty nine healthy subjects aged between 22 and 89 years were recruited for the study. We found that serum PON1 activity significantly decreased with age (r=-0.38, p<0.0001) while its arylesterase activity as well as its concentration in the serum did not change significantly. HDL concentrations remained unchanged with age, however, Apo A1 concentration showed a slight negative but significant correlation with age (r=-0.19, p<0.027). Moreover, the total cholesterol concentration was positively and significantly correlated with age (r=0.40, p<0.001). Thus, our results suggest that the decrease in PON1 activity cannot be explained by the decrease in Apo A1 concentrations with age. HDL from elderly subjects was more susceptible to oxidation than HDL from young subjects measured by higher lipid peroxidation rate. Thus, the decrease in PON1 activity may contribute to this increased susceptibility of HDL to oxidation with aging. Altogether our results suggest that the decrease in PON1 activity may be related to the development of oxidative stress conditions with aging and the increased HDL susceptibility to oxidation in elderly subjects.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Experimental Gerontology. - 39 : 1 (2004), p. 56-66. -
További szerzők:Paragh György (1953-) (belgyógyász) Deschene, Elaine Fülöp Tamás Jr Khalil, Abdelouahed
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
Borító:

6.

001-es BibID:BIBFORM013314
Első szerző:Szekanecz Zoltán (reumatológus, belgyógyász, immunológus)
Cím:Malignancies in Autoimmune Rheumatic Diseases : a Mini-Review / Szekanecz Zoltán, Szekanecz Éva, Bakó Gyula, Shoenfeld Yehuda
Dátum:2011
ISSN:0304-324X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gerontology. - 57 : 1 (2011), p. 3-10. -
További szerzők:Szekanecz Éva (1968-) (onkológus szakorvos) Bakó Gyula (1951-) (belgyógyász) Shoenfeld, Yehuda
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
Borító:

7.

001-es BibID:BIBFORM076741
035-os BibID:(WoS)000493116300012 (Scopus)85072056313
Első szerző:Tarantini, Stefano
Cím:Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice : translational Relevance of Decreased Cadence and Increased Gait Variability / Tarantini Stefano, Yabluchanskiy Andriy, Fülöp Gábor A., Kiss Tamas, Perz Aleksandra, O'Connor Daniel, Johnson Emily, Sorond Farzaneh, Ungvari Zoltan I., Csiszar Anna
Dátum:2019
ISSN:1079-5006
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journals Of Gerontology Series A-Biological Sciences And Medical Sciences. - 74 : 9 (2019), p. 1417-1421. -
További szerzők:Yabluchanskiy, Andriy Fülöp Gábor Áron (1988-) (általános orvos) Kiss Tamás Perz, Aleksandra O'Connor, Daniel Johnson, Emily Sorond, Farzaneh A. Ungvári Zoltán Csiszár Anna
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

8.

001-es BibID:BIBFORM045397
Első szerző:Urbán László
Cím:On the role of aging in the etiology of autoimmunity / László Urbán, Beáta Bessenyei, Marietta Márka, Imre Semsei
Dátum:2002
ISSN:0304-324X
Megjegyzések:Several types of diseases, among others autoimmune illnesses, could be coupled with the general processes of aging. The two-edged sword of immune defense is directed on one side against environmental attacks and on the other against the body itself. However, one has to make a difference between normal (physiological) clearance and autoimmune diseases, although both sides of autoimmunity are influenced by the general processes of senescence. Aging of the thymus seems to be one of the key elements in the etiology of autoimmunity, although other cell types and their aging also play a substantial role in this process. Spontaneous genetic instability, acquired genetic mutations due to aging and the age-related alterations in the information level of the body may together be important elements in the pathomechanism of both physiological autoimmunity and autoimmune diseases. Nevertheless, physiological autoimmunity seems to be directed mostly by natural factors (such as aging and apoptosis) but primary autoimmune diseases may be caused by genetic instability that is enhanced by aging as well.Copyright 2002 S. Karger AG, BaselPMID: 11961373
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gerontology. - 48 : 3 (2002), p. 179-184. -
További szerzők:Bessenyei Beáta (1974-) (molekuláris biológus) Márka Marietta Semsei Imre (1954-) (vegyész, gerontológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

9.

001-es BibID:BIBFORM071096
Első szerző:van der Kraan, Peter
Cím:Age-Related Alterations in Signaling Pathways in Articular Chondrocytes : implications for the Pathogenesis and Progression of Osteoarthritis - A Mini-Review / van der Kraan Peter, Matta Csaba, Mobasheri Ali
Dátum:2017
ISSN:0304-324X
Megjegyzések:Musculoskeletal conditions are a major burden on individuals, healthcare systems, and social care systems throughout the world, with indirect costs having a predominant economic impact. Aging is a major contributing factor to the development and progression of arthritic and musculoskeletal diseases. Indeed, aging and inflammation (often referred to as ♭inflammaging') are critical risk factors for the development of osteoarthritis (OA), which is one of the most common forms of joint disease. The term ♭chondrosenescence' has recently been introduced to define the age-dependent deterioration of chondrocyte function and how it undermines cartilage function in OA. An important component of chondrosenescence is the age-related deregulation of subcellular signaling pathways in chondrocytes. This mini-review discusses the role of age-related alterations in chondrocyte signaling pathways. We focus our attention on two major areas: age-dependent alterations in transforming growth factor-? signaling and changes in protein kinase and phosphoprotein phosphatase activities in aging chondrocytes. A better understanding of the basic signaling mechanisms underlying aging in chondrocytes is likely to facilitate the development of new therapeutic and preventive strategies for OA and a range of other age-related osteoarticular disorders.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gerontology 63 : 1 (2017), p. 29-35. -
További szerzők:Matta Csaba (1980-) (molekuláris biológus, genetikus, angol szakfordító) Mobasheri, Ali
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

10.

001-es BibID:BIBFORM013972
Első szerző:Váróczy László (belgyógyász, haematológus)
Cím:Malignant lymphomas in the elderly : a single institute experience highlights future directions / Váróczy László, Dankó Alpár, Simon Zsófia, Gergely Lajos, Ress Zsuzsa, Illés Árpád
Dátum:2007
ISSN:0167-4943
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Archives Of Gerontology And Geriatrics. - 45 : 1 (2007), p. 43-53. -
További szerzők:Dankó Alpár Simon Zsófia (1977-) (belgyógyász, haematológus) Gergely Lajos (1965-) (belgyógyász, haematológus) Ress Zsuzsa (1976-) (belgyógyász) Illés Árpád (1959-) (belgyógyász, haematológus, onkológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
elektronikus változat
Borító:
Rekordok letöltése1 
Corvina könyvtári katalógus v8.2.27 © 2023 Monguz kft. Minden jog fenntartva.