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1.

001-es BibID:BIBFORM007201
Első szerző:Csorba Roland (szülész-nőgyógyász, gyermeknőgyógyász)
Cím:Female child sexual abuse within the family in a Hungarian County / Csorba R., Lampé L., Borsos A., Balla L., Póka R., Oláh É.
Dátum:2006
Megjegyzések:BACKGROUND: The aim of the study was to analyze the characteristics ofintrafamiliar female child sexual abuse and to explore common features that maybe utilized as targets for possible methods of prevention. We also described themedical and legal approaches to handling child neglect. METHODS: This was adescriptive, cross-sectional study on 52 sexually abused girls under the age of18 at the Department of Obstetrics and Gynecology, Medical and Health ScienceCenter of Debrecen. We prospectively recorded the data of all cases.Intrafamiliar events were defined if the victim and perpetrator belonged to thesame family. Legal outcomes were also recorded. RESULTS: During the 16-yearperiod, 209 cases of sexual abuse were seen in our clinic, 52 of them had beeninvolved in child sexual abuse within the family. This accounts for 25% ofadolescent cases. Eighty-six percent of the victims were pupils, 50% of them werebetween 11 and 14 years of age. The perpetrator was the victim's father in 44%,and the stepfather in 40%. There was a slight difference between the type ofnot significant. The abuse occurred on multiple occasions in 52%. The occurrencerate of assault was the highest in the summer season (58%), mostly in theafternoon (42%) and it took place almost exclusively at home (98%). The motheraccompanied the victim in 38% of the cases and the police in 40%. Vaginalpenetration was the type of abuse in 75%, and sexual perversion in 25%. Sixvictims were physically injured, the presence of sperm could be confirmed onvulvovaginal smears in 2 cases. One pregnancy conceived. Nine cases were reportedto the police and as a result of legal proceedings, 5 perpetrators have beensentenced. CONCLUSION: The majority of crimes take place within the family andare disclosed after multiple episodes. The small proportion of reported sexualassaults is the consequence of the lack of harmony between the Hungarianconditions of emergency care and the criminal law. Prevention calls for attentionat all levels of child education, observation at off-school times, earlyinvolvement of health professionals, applying standardized medical guidelines andthe modification of jurisdiction.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Gynecologic and Obstetric Investigation. - 61 : 4 (2006), p. 188-193. -
További szerzők:Lampé László (1929-2021) (szülész-nőgyógyász) Borsos Antal (1939-) (szülész-nőgyógyász, gyermeknőgyógyász) Balla Lajos (jogász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Oláh Éva (1943-2019) (gyermekgyógyász, klinikai genetikus)
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2.

001-es BibID:BIBFORM117861
035-os BibID:(Scopus)85190562884 (WOS)001209557600004
Első szerző:Herman Tünde (orvos)
Cím:Hashimoto's thyroiditis negatively influences ICSI outcome in euthyroid women on T4 substitution therapy; a retrospective study / Tünde Herman, Péter Török, Antonio Simone Laganà, Vito Chiantera, Renato Venezia, Attila Jakab
Dátum:2024
ISSN:0378-7346
Megjegyzések:Abstract Objective: To analyze the impact of thyroid autoimmunity (TAI) on reproductive outcome parameters of ICSI cycles as compared to TAI negative ICSI cycles. Design: In this single IVF center retrospective study 86 infertile women with elevated TPOAb or TGAb levels, but euthyroid after thyroxine replacement (study group), were compared to 69 female patients with no thyroid abnormalities (controls). Following ICSI treatment fertilization rate (FR), clinical pregnancy rate (CPR), miscarriage rate (MR) and live birth rate (LBR) were analyzed. Materials, Setting, Methods: All subjects with various infertility factors were treated with ICSI in university based IVF center. Patients in the study group received thryroxine replacement and were euthyreoid at IVF treatment. Before the IVF cycles endocrinological parameters were uniformly assessed: thyroid function and antibodies, reproductive hormones (AMH, FSH, LH, E2, PRL, testosterone, DHEAS, 17-OHP, AD) and OGTT (0-60-120 min glucose and insulin). Following descriptive comparison of laboratory parameters, age adjusted analyses of FR, CPR, MR and LBR were performed. Results: TAI positive women were older (mean age 35.31?4.95 vs. 32.15?4.87 years; p=0.002), had higher FSH (8.4?3.4 vs. 7.4?2.32 U/L; p=0.024), higher E2 (53.94?47.61 vs. 42.93?18.92 pg/ml; p=0.025) levels, while AMH (2.88?2.62 vs. 3.61?1.69 ng/ml; p=0.0002) was lower. There were no differences in TSH levels (1.64?0.96 vs. 1.66?0.65 uIU/ml; p=0.652) between the two groups. FT3 (2.63?0.58 vs. 2.98?0.55 pg/ml; p=0.002) was lower and FT4 (1.3?0.29 vs. 1.13?0.21 ng/dl; p=0.0002) was higher in the TAI positive group, reflecting clinically irrevelant differences. Egg cell counts (6?3.8 vs. 7.5?3.95; p=0.015) were lower in TAI and remained so following age adjustment. Although the overall ICSI FR did not differ (62.9 % vs. 69.1 %, p=0.12), it was lower for patients under 35 with TAI showing decreasing differences in line with age. The CPR (36.04 % vs. 69.56 %; p<0.001), LBR (23.25 % vs. 60.86 %; p<0.001) were lower, the MR (35.48 % vs. 12.5 %; p=0.024) was higher in the TAI group and these differences remained after age adjustment. Limitations: Since the higher age of the study group may interfere with the effect of TAI, age adjustment calculations were necessary to perform to eliminate this confounding factor. Conclusion: Despite optimal thyroid supplementation in clinical or subclinical hypothyreoidism, the presence of TAI negatively influences clinical pregnancy rate and is connected to a higher miscarriage rate, thus resulting in a lower live birth rate after ICSI. Decreased fertilization rate with ICSI in TAI patients may also contribute to poorer outcomes, especially in younger women.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
IVF
ICSI
Hashimoto thyreoiditis
Megjelenés:Gynecologic And Obstetric Investigation. - 89 : 2 (2024), p. 150-158. -
További szerzők:Török Péter (1975-) (szülész-nőgyógyász) Laganà, Antonio Simone Chiantera, Vito Venezia, Renato Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
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3.

001-es BibID:BIBFORM075687
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:The Effects of Heat Exposure on Vaginal Smooth Muscle Cells : elastin and Collagen Production / Bence Kozma, Keith Candiotti, Róbert Póka, Péter Takács
Dátum:2018
ISSN:0378-7346
Megjegyzések:Aims: To evaluate smooth muscle cells (SMCs) proliferation and elastin and collagen production after heat exposure (65 ? C). Methods: Samples were taken from the anterior vaginal wall, SMCs were cultured, and heated to 65 ? C for 30 and 60 s. Cell proliferation was assessed; tropoelastin and collagen production was measured. Results: Heat does not affect SMC proliferation at 65 ? C neither at 30 nor at 60 s. Surfacedeposited elastin level was significantly increased after heat exposure (mean ? SD, 30 s 155 ? 5% of control [p < 0.01] and 60 s 516 ? 40% of control [p < 0.01]). Tropoelastin levels in the culture media were significantly lower after 60 s of heat exposure (mean ? SD, 30 s 102 ? 5% of control [p = ns] and 60 s 70 ? 2% of control [p = 0.04]). Significant increase in surface-deposited collagen production was found (mean ? SD, 30 s 170 ? 6% of control [p < 0.01] and 60 s 123 ? 6% of control [p < 0.01]), but no such elevation was measured in the media after heat exposure (mean ? SD, 30 s 120 ? 20% of control [p = ns] and 60 s 100 ? 20% of control [p = ns]). Conclusion: When SMCs are exposed to heat there is significant elevation in collagen and elastin production. Changes in the composition of the extracellular matrix after heat exposure may contribute to vaginal wall remodeling.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gynecologic And Obstetric Investigation. - 83 : 3 (2018), p. 247-251. -
További szerzők:Candiotti, Keith Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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DOI
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4.

001-es BibID:BIBFORM074341
035-os BibID:(WOS)000454454600014 (Scopus)85049921240
Első szerző:Török Péter (szülész-nőgyógyász)
Cím:Digital Image Analysis with Fully Connected Convolutional Neural Network to Facilitate Hysteroscopic Fibroid Resection / Péter Török, Balázs Harangi
Dátum:2018
ISSN:0378-7346
Megjegyzések:AimsTo determine the accuracy of deep neural network in identifying the plane between myoma and normal myometrium.MethodsOn the images of surgery, different structures were signed and annotated for the training phase. After the appropriate training of the deep neural network with 4688 images from that training set, 1600 formerly unseen images were used for testing.Indication for surgery was heavy menstrual bleeding and hysteroscopic finding was submucous fibroid. Operative intervention was fibroid resection. Recorded videos of transcervical resection of myoma in 13 cases were used for the study. Different filters and procedures were applied by the fully convolutional neural network (FCNN) for identifying previously annotated structures.ResultsPreviously manually annotated images and the manually drawn bitmasks were used for training the applied fully convolutional neural network and then this pre-trained network was used for automatic segmentation of normal myometrium in an unseen video frame. The segmentation pixel-wise accuracy achieved the 86.19% considering the Hausdorff metric.ConclusionUsing deep learning technique in analyzing process of endoscopic video frame could help in real-time identification of structures while performing endoscopic surgery.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
convolutional neural network
deep learning
endoscopy
hysteroscopy
fibroid
Megjelenés:Gynecologic And Obstetric Investigation. - 83 : 6 (2018), p. 615-619. -
További szerzők:Harangi Balázs (1986-) (programtervező matematikus)
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DOI
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5.

001-es BibID:BIBFORM025359
Első szerző:Zatik János (szülész-nőgyógyász)
Cím:Comparison of cerebral blood flow velocity as measured in preeclamptic, healthy pregnant, and nonpregnant women by transcranial Doppler sonography / Zatik J., Aranyosi J., Mihálka L., Páll D., Major T., Fülesdi B.
Dátum:2001
Megjegyzések:To test the hypothesis that the middle cerebral artery blood flow velocity (MCAV) is altered in preeclamptic pregnant women as compared with healthy pregnant and nonpregnant women. METHODS: Preeclamptic (n = 21) and healthy pregnant (n = 17) as well as healthy nonpregnant (n = 29) women underwent transcranial Doppler MCAV measurements. The mean MCAV values were compared between the different groups. Anova combined with Bonferroni correction was used for statistical analysis. RESULTS: The MCAV was significantly higher in nonpregnant women (mean +/- SE 73.0 +/- 2.12 cm/s) as compared with healthy pregnant women (67.0 +/- 1.8 cm/s, p = 0.0356). Preeclamptic women showed significantly higher MCAV values (83.5 +/- 2.1 cm/s) as compared with nonpregnant females (73.0 +/- 2.12 cm/s, p = 0.0014). Similar to nonpregnant women, healthy pregnant women showed lower MCAV values (67.0 +/- 1.8 cm/s) as compared with preeclamptic women (83.5 +/- 2.1 cm/s, p = 0.001). After Bonferroni correction the MCAV values in patients suffering from preeclampsia were still statistically significantly higher as compared with the two other groups. CONCLUSIONS: We detected increased resting MCAV values in pregnant women with preeclampsia. In our opinion, this finding refers to arteriolar dilation of the resistance vessels of the brain. Further studies are needed to prove altered vasoreactivity responses of the brain resistance arterioles in preeclampsia.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gynecologic and Obstetric Investigation. - 51 : 4 (2001), p. 223-227. -
További szerzők:Aranyosi János (1963-) (szülész-nőgyógyász) ifj. Mihálka László (1950-) (neurológus) Páll Dénes (1967-) (belgyógyász, kardiológus) Major Tamás (1963-) (szülész-nőgyógyász) Fülesdi Béla (1961-) (aneszteziológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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