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1.

001-es BibID:BIBFORM031210
Első szerző:Cserni Tamás (gyermeksebész)
Cím:In utero incarceration of congenital diaphragmatic hernia / Tamas Cserni, Edit Polonkai, Olga Torok, Andrea Nagy, Istvan Pataki, Anna May Long, Peter Cserni, Laszlo id. Orosz, Gyorgy Balla
Dátum:2011
ISSN:0022-3468
Megjegyzések:In utero diagnosis of incarcerated congenital diaphragmatic hernia has never been reported. In our case, congenital diaphragmatic hernia presented at 34 weeks of gestation with dilated bowel loops, pleural effusion, and ascites on fetal ultrasound. Preterm delivery and emergency exploration revealed a tight posterolateral diaphragmatic defect with extensive bowel infarction.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
egyetemen (Magyarországon) készült közlemény
Megjelenés:Journal of Pediatric Surgery. - 46 : 3 (2011), p. 551-553. -
További szerzők:Polonkai Edit (1965-) (csecsemő és gyermekgyógyász, neonatológus) Török Olga (1956-) (szülész-nőgyógyász, humángenetikus) Nagy Andrea (1958-) (csecsemő és gyermekgyógyász, neonatológus) Pataki István (1975-) (csecsemő és gyermekgyógyász, neonatológus) Long, Anna May Cserni Péter id. Orosz László Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus)
Pályázati támogatás:TÁMOP-4.2.1./B-09/1/KONV-2010-0007
TÁMOP
Haemostasis thrombosis és vascularis biológia
OTKA-K75883
OTKA
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Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM031164
Első szerző:Cserni Tamás (gyermeksebész)
Cím:The effect of age on colocalization of acetylcholinesterase and nicotinamide adenine dinucleotide phosphate diaphorase staining in enteric neurons in an experimental model / Tamás Cserni, Sri Paran, Prem Puri
Dátum:2007
ISSN:0022-3468
Megjegyzések:Cholinergic and nitrergic neurons form 2 main subpopulations of the myenteric neurons, and they have been the targets of detailed morphological investigations in bowel motility disorders. However, little is known regarding the colocalization of neurotransmitters within the same enteric neurons. The aim of this study was to determine the histochemical colocalization of cholinergic and nitrergic neurons in the porcine distal large bowel myenteric plexus from fetal to adulthood.METHODS:Distal large bowel specimens were taken from 6 randomly selected age groups (3 animals in each group) from midway of gestation to adulthood. The myenteric plexus was exposed using whole-mount technique. After nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) staining, cells per ganglion were counted. Then the specimens were stained with acetylcholinesterase (AChE), and the cells that were stained with individual enzymes and with both enzymes were counted.RESULTS:Colocalization of AChE and NADPH-d was seen in all age groups, and it was highest during the mid part of gestation (30%) and decreased steadily thereafter into adulthood (8%). The individual number of NADPH-d- and AChE-positive neurons per ganglion remained constant till 4 weeks of age and significantly increased thereafter into adulthood.CONCLUSION:The use of double-labeling histochemical technique shows for the first time the colocalization of cholinergic and nitrergic activity in a large population of enteric neurons in the late fetal and newborn period. Age-related loss of cholinergic and nitrergic colocalization in the myenteric plexus is most likely a maturational process.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Journal Of Pediatric Surgery. - 42 : 2 (2007), p. 300-304. -
További szerzők:Paran, Sri Puri, Prem
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Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM031162
Első szerző:Cserni Tamás (gyermeksebész)
Cím:New hypothesis on the pathogenesis of ileocecal intussusception / Tamas Cserni, Sri Paran, Prem Puri
Dátum:2007
ISSN:0022-3468
Megjegyzések:Ileocecal intussusception is a relatively common surgical emergency in infants and young children. The etiology of intussusception is not clearly understood. Nitric oxide (NO) is a major inhibitory neurotransmitter in the enteric nervous system, which causes relaxation of the smooth muscles. In a lipopolysaccharide-induced experimental model of intussusception, altered intestinal motility is shown to be the result of increased NO released from various inflammatory mediators, which in turn leads to increased incidence of intussusception. The aim of this study was to examine the age-related changes in the nitrergic innervation of the ileocecal valve (ICV) to gain insights into the pathogenesis of intussusception.METHOD:Whole-mount preparations of the myenteric plexus from the ileum, ICV, and proximal colon were stained using NADPH diaphorase histochemistry in newborn piglets (n = 3), 4-week-old (n = 3), 12-week-old (n = 3), and adult pigs (n = 3). Using light microscopy, the number of ganglia per square centimeter, the number of cells per ganglion, and the number of ganglion cells per square centimeter were determined.RESULTS:There were striking regional and age-related differences in nitrergic innervation of myenteric plexus. Density of nitrergic neurons was significantly higher in the ICV than in the terminal ileum and proximal large bowel in the young animals (P < .001).CONCLUSION:These findings suggest that the inflammatory reactions that usually precede intussusception may cause overproduction of NO by the nitrergically hyperinnervated ICV causing relaxation of the ICV and thereby facilitating ileocecal intussusception.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Journal of Pediatric Surgery. - 42 : 9 (2007), p. 1515-1519. -
További szerzők:Paran, Sri Puri, Prem
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Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM050653
035-os BibID:PMID:23480916
Első szerző:Pataki István (csecsemő és gyermekgyógyász, neonatológus)
Cím:Recycling of bowel content : the importance of the right timing / Istvan Pataki, Judit Szabo, Petra Varga, Andrea Berkes, Andrea Nagy, Fiona Murphy, Antonino Morabito, George Rakoczy, Tamas Cserni
Dátum:2013
ISSN:0022-3468
Megjegyzések:Extracorporeal stool transport (recycling of chyme discharged from the proximal stoma end to the distal end of a high jejunostomy or ileostomy) is thought to be beneficial in preventing malabsoprtion, sodium loss, cholestasis and atrophy of the distal intestine until restoration of the intestinal continuity becomes possible. However little is known about its adverse effects. Our aim was to investigate the microbiological safety of recycling. MATERIAL AND METHOD: Native samples were taken from the proximal stoma in 5 premature neonates who underwent an ileostomy or a jejunostomy due to necrotising enterocolitis, for qualitative culture. The first sample was drawn immediately after the change of the stoma bag, further samples were sent from the stoma bag at 30, 60, 90, 120, 150, and 180min later. The samples were inoculated by calibrated loops onto blood agar (5% sheep blood), eosin-methylene blue agar and anaerobic blood agar, respectively (Oxoid). The aerobic plates were incubated for 18-20 h at 5% CO2, whereas the anaerobic plates were incubated for 24-48 h in an anaerobic chamber (Concept 400). The bacterial strains were identified to species level by specific biochemical reactions, RapID-ANA II system (Oxoid) and ID32E, Rapid ID 32 Strep ATB automatic system cards (bioMérieux). RESULTS: The number of colony forming unit (CFU) of Gram-negative bacteria (mainly E. coli) exponentially increased after 30 min and reached 10(5)/ml after 120 min. Gram-positive strains (primarily E. faecalis) were detected after 60 min and CFU increased to 10(5)/ml after 120 min. The number of anaerobic (principally Bacteroides fragilis) CFU started to increase after 120 min. In two cases coagulase negative Staphylococcus strains were isolated the earliest in the chyme. The average of total CFU approached 10(5)/ml after 90 min and exceeded 10(5)/ml after 120 min. CONCLUSION: The chyme in the stoma bag is colonized by commensal facultative pathogenic enteral/colonic as well as skin flora species after 120 min. Recycling of stoma bag content may be dangerous after 90 min.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Pediatric Surgery. - 48 : 3 (2013), p. 579-584. -
További szerzők:Szabó Judit (1963-) (szakorvos, klinikai mikrobiológus) Varga Petra (1981-) (orvos) Berkes Andrea (1973-) (csecsemő- és gyermekgyógyász) Nagy Andrea (1958-) (csecsemő és gyermekgyógyász, neonatológus) Murphy, Fiona Morabito, Antonino Rákóczy György Cserni Tamás (1967-) (gyermeksebész)
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Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM024426
035-os BibID:(Wos)000296373200004 (Scopus)80054766185
Első szerző:Polonkai Edit (csecsemő és gyermekgyógyász, neonatológus)
Cím:Pyloric atresia associated with Dieulafoy lesion and gastric dysmotility in a neonate / Edit Polonkai, Andrea Nagy, István Csízy, Csaba Molnár, Tamás Rőszer, György Balla, Tamás Józsa
Dátum:2011
Megjegyzések:In this case study, we report a male infant with pyloric atresia, extreme gastric distension, and a caliber-persistent gastric artery (Dieulafoy lesion) with massive gastric bleeding. After a transverse pyloroplasty and endoscopic hemoclip application to the caliber-persistent gastric artery, very slow gastric emptying developed, which required repeated surgical interventions. Gastroduodenostomy failed to promote gastric emptying. The intraoperative and postmortem histologic examinations of the gastric wall revealed a loss of interstitial cells of Cajal, which possibly explains the extreme motility disorder. Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Egészség- és Környezettudomány
Megjelenés:Journal of Pediatric Surgery. - 46 : 10 (2011), p. E19-E23. -
További szerzők:Nagy Andrea (1958-) (csecsemő és gyermekgyógyász, neonatológus) Csízy István (1948-) (gyermekgyógyász, gyermeksebész) Molnár Csaba (1979-) (pathológus) Röszer Tamás (1979-) (orvos, biológus) Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus) Józsa Tamás (1969-) (gyermeksebész, urológus)
Pályázati támogatás:TÁMOP-4.2.1/B-09/1/KONV-2010-0007
TÁMOP
Újszülött-, és gyermekkori érbetegségek. A hemoxigenáznak és a ferritinnek, mint protektív stressz fehérjéknek szerepe intenzív ellátást igénylő újszülöttek és gyermekek akut és krónikus betegségeiben
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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6.

001-es BibID:BIBFORM113548
035-os BibID:(scopus)85159284761
Első szerző:Varga Alexandra
Cím:Medium-Term Results of Staged Laparoscopic Traction Orchiopexy for Intra-abdominal Testes : A Multicenter Analysis / Varga Alexandra, Kardos Dániel, Radványi Ádám, Vajda Péter, Sasi Szabó László, Kovács Tamás
Dátum:2023
ISSN:0022-3468
Megjegyzések:Background: Staged laparoscopic traction orchiopexy (SLTO) is a novel technique for the intra-abdominal testis (IAT) based on elongation of the testicular vessels without separating them. This multicenter study evaluated the medium-term results of this technique. Methods: Data of SLTO performed in three pediatric surgical centers between 2013 and 2020 were analyzed retrospectively. In 2021, physical and Doppler ultrasound examinations were performed to determine the position and viability of testes. Success was defined as an intra-scrotal testicle without atrophy. Results: SLTO was performed on 48 cases (55 testes, 7 bilateral). Mean age at first stage was 2.9 (0.8?12.6) years. High intra-abdominal testes were found in 16.4% and in 60% morphological abnormalities were observed. To fix the testes to the abdominal wall monofilament suture was used in 67.3%, braided in 29.1%. Mean time between the two stages was 16.4 weeks; three testes required redo traction. Perioperative complications occurred in 21 patients (38.2%) including insufficient fixation (11), testicular atrophy (4), wound complications (4), adhesion of the spermatic cords (1) and hydrocele (1). In case of insufficient fixation monofilament sutures were used in 90.9%. In 2021 38 patients (43 testes) had physical and 36 patients (41 testes) had ultrasound examinations. Mean follow-up was 2.7 (0.34?7.9) years. Altogether five atrophies were identified, and three testicular ascents (7.0%) occurred. The overall success rate was 82.2%. Conclusions: SLTO may be a feasible alternative to conventional treatments of IATs. Additionally, braided suture seems to be a better option to fix the testicle to the abdominal wall. Level of Evidence: LEVEL IV. ? 2023 The Author(s)
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal Of Pediatric Surgery. - 58 : 10 (2023), p. 2020-2026. -
További szerzők:Kardos Dániel Radványi Ádám Vajda Péter Sasi Szabó László András (1974-) (sebész) Kovács Tamás (gyermekgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
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