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001-es BibID:	BIBFORM073726
Első szerző:	Andrássy László
Cím:	Laser-induced plasma spectroscopy (LIPS) : use of a geological tool in assessing bone mineral content / Andrássy László, Gomez Izabella, Horváth Ágnes, Gulyás Katalin, Pethö Zsófia, Juhász Balázs, Bhattoa Harjit Pal, Szekanecz Zoltan
Dátum:	2018
ISSN:	0268-8921
Megjegyzések:	Bone may be similar to geological formulations in many ways. Therefore, it may be logical to apply laser-based geological techniques in bone research. The mineral and element oxide composition of bioapatite can be estimated by mathematical models. Laser-induced plasma spectrometry (LIPS) has long been used in geology. This method may provide a possibility to determine the composition and concentration of element oxides forming the inorganic part of bones. In this study, we wished to standardize the LIPS technique and use mathematical calculations and models in order to determine CaO distribution and bone homogeneity using bovine shin bone samples. We used polished slices of five bovine shin bones. A portable LIPS instrument using high-power Nd++YAG laser pulses has been developed (OpLab, Budapest). Analysis of CaO distribution was carried out in a 10 ? 10 sampling matrix applying 300-?m sampling intervals. We assessed both cortical and trabecular bone areas. Regions of interest (ROI) were determined under microscope. CaO peaks were identified in the 200?500 nm wavelength range. A mathematical formula was used to calculate the element oxide composition (wt%) of inorganic bone. We also applied two accepted mathematical approaches, the Bartlett's test and frequency distribution curve-based analysis, to determine the homogeneity of CaO distribution in bones. We were able to standardize the LIPS technique for bone research. CaO concentrations in the cortical and trabecular regions of B1?5 bones were 33.11 ? 3.99% (range 24.02?40.43%) and 27.60 ? 7.44% (range 3.58?39.51%), respectively. CaO concentrations highly corresponded to those routinely determined by ICP-OES. We were able to graphically demonstrate CaO distribution in both 2D and 3D. We also determined possible interrelations between laser-induced craters and bone structure units, which may reflect the bone structure and may influence the heterogeneity of CaO distributions. By using two different statistical methods, we could confirm if bone samples were homogeneous or not with respect to CaO concentration distribution. LIPS, a technique previously used in geology, may be included in bone research. Assessment of element oxide concentrations in the inorganic part of bone, as well as mathematical calculations may be useful to determine the content of CaO and other element oxides in bone, further analyze bone structure and homogeneity and possibly apply this research to normal, as well as diseased bones.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk laser-induced plasma spectrometry LIPS Element oxide CaO Mathematical model Bioapatite Bartlett's test frequency characteristic homogeneity
Megjelenés:	Lasers In Medical Science. - 33 : 6 (2018), p. 1225-1236. -
További szerzők:	Gomez Izabella (1981-) (orvos) Horváth Ágnes (1985-) (reumatológus) Gulyás Katalin (reumatológus) Pethő Zsófia (1981-) (reumatológus, immunológus) Juhász Balázs (1973-) (orvos, onkológus) Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus)
Pályázati támogatás:	105073 OTKA 4.2.4.A/2-11/1-2012-0001 TÁMOP
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001-es BibID:	BIBFORM073118
Első szerző:	Bhatta, Anil Kumar
Cím:	A review of the mechanism of action of lasers and photodynamic therapy for onychomycosis / Anil Kumar Bhatta, Uma Keyal, Xiuli Wang, Emese Gellén
Dátum:	2017
ISSN:	0268-8921
Megjegyzések:	Onychomycosis is one of the most commondiseases in the field of dermatology. It refers to thefungal infection of the nail plate or nail bed with highincidence in the general population. The available treatmentoptions for onychomycosis have limited use due toside effects, drug interactions, and contraindications,which necessitates the application of an alternative treatmentfor onychomycosis. In the recent years, lasers andphotodynamic therapy (PDT) have been recognized asalternative treatment options. Most of the previous studieshave found them to be safe and effective treatmentmodalities in this indication; however, the results variedgreatly and the in vitro and in vivo outcomes are contradictory.In the present review, studies related to themechanism of action of lasers and PDT for the treatmentof onychomycosis will be discussed, with a focuson to find explanation to the contradictory results.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Laser therapy Photodynamic therapy Onychomycosis
Megjelenés:	Lasers In Medical Science 32 : 2 (2017), p. 469-474. -
További szerzők:	Keyal, Uma Wang, Xiuli Gellén Emese (1986-) (bőrgyógyász)
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001-es BibID:	BIBFORM102402
Első szerző:	Farkas Antal (urológus, onkológus)
Cím:	Holmium:YAG laser treatment of ureteral calculi : a 5-year experience / Farkas A., Péteri L., Lőrincz L., Salah M. A., Flaskó T., Varga A., Tóth Cs.
Dátum:	2006
ISSN:	0268-8921
Megjegyzések:	The purpose of this study was to provide an account of the 5-year experience we have gained using holmium:yttrium?aluminium-garnet (Ho:YAG) lasertripsy in the treatment of ureteral stones. One-hundred thirty-seven transurethral ureterolithotripsies were performed in 131 patients. A Ho:YAG laser device, fibres with diameters of 360 and 550 ?m, a video camera as well as semi-rigid and flexible ureterorenoscopes were used. Results showed that the direct success rates?which meant stone-free ureters on the first post-operative day?in the upper, middle and lower ureters were 84.6, 88.7 and 94.8%, respectively. The final success rates?which meant stone-free ureters 4 weeks after the operation without a second intervention?were 84.6, 96.7 and 96.7%, respectively. The pulsatile Ho:YAG laser beam fragmented all kinds of stones easily. No ureteral stricture or reflux was identified during the follow-up period. The advantages of Ho lasertripsy outweighed its disadvantages. Based on our experience, the Ho:YAG laser is one of the most effective and safest energy sources in the treatment of ureteral calculi.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Lasertripsy Ureteral stones Holmium:YAG laser Ureteroscopy
Megjelenés:	Lasers In Medical Science. - 21 : 3 (2006), p. 170-174. -
További szerzők:	Péteri László (urológus Salgótarján) Lőrincz László (1965-) (urológus) Salah, Morshed Ali (1965-) (urológus) Flaskó Tibor (1960-) (urológus) Varga Attila (1949-) (urológus, andrológus) Tóth Csaba (1940-) (urológus, sebész)
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001-es BibID:	BIBFORM074243
Első szerző:	Rentka Anikó (szemész)
Cím:	Evaluation of carbon dioxide laser therapy for benign tumors of the eyelid margin / Rentka Aniko, Grygar Jan, Nemes Zoltan, Kemeny-Beke Adam
Dátum:	2017
ISSN:	0268-8921
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Carbon dioxide laser Laser surgery Eyelid margin Benign tumor Complication
Megjelenés:	Lasers In Medical Science 32 : 8 (2017), p. 1901-1907. -
További szerzők:	Grygar, Jan Nemes Zoltán (1942-) (patológus) Kemény-Beke Ádám (1968-2021) (szemész)
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