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1.

001-es BibID:BIBFORM049640
035-os BibID:PMID:24297095
Első szerző:Bazsó A. (Budapest)
Cím:Aseptic necrosis at multiple localisations in a lupus patient with lymphoma / A. Bazso, T. Bazso, P. Szodoray, G. Poor, E. Kiss
Dátum:2014
ISSN:0937-941X
Megjegyzések:Avascular or aseptic necrosis is a well-defined entity leading to the degradation of cellular elements of the bone. The pathogenesis of osteonecrosis (ON) is still unknown. There are two main types of ON: traumatic or non-traumatic. Several clinical entities could associate with ON, systemic diseases, environmental factors, pregnancy, systemic autoimmune or rheumatic diseases, thrombophilia, corticosteroid therapy, cytotoxic dugs, infections, metabolic and hematologic diseases, etc. Corticosteroids (CS) are still the most frequently used therapeutic options in the early phase and during flares of these diseases. Inflammatory cytokines and antibodies have been described to participate in the pathogenesis of ON. The infiltrative disorders of the bone marrow could also contribute to the development of ON. Hereby, we describe a female patient with NHL followed by SLE in whom ON has developed at least in two localisations. Lupus flare, long-term CS therapy, lymphoma relapse or the presence of antiphospholipid antibodies were excluded. Although the bi-localised ON could be contributed to immunologic factors or trauma, the exact aetiology in this case could not be elucidated.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Osteoporosis International 25 : 4 (2014), p. 1415-1417. -
További szerzők:Bazsó Tamás (1974-) (ortopéd sebész) Szodoray Péter (1973-) (belgyógyász, orvos) Poór Gyula Kiss E.
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2.

001-es BibID:BIBFORM042525
035-os BibID:PMID: 12730763
Első szerző:Berczi Csaba (urológus, sebész, onkológus)
Cím:Comparison of calcium and alfacalcidol supplement in the prevention of osteopenia after kidney transplantation / Berczi C., Asztalos L., Kincses Z., Balogh A., Löcsey L., Balázs G., Lukács G.
Dátum:2003
ISSN:0937-941X
Megjegyzések:The aim of this observational study was to compare the effect of calcium and alfacalcidol supplementation on the regression of hyperparathyroidism and on prevention of osteopenia in patients up to 3 years after renal transplantation. Two historical cohorts were compared for that purpose. One hundred and fifty-nine patients received calcium carbonate supplement (group 1), while 81 patients were treated with alfacalcidol (group 2). Serum Ca, phosphate (P), Mg, creatinine, alkaline phosphatase (AP) and parathyroid hormone (PTH) levels were determined before and after transplantation in the two groups, for 3 years. Femoral neck and lumbar spine bone mineral density (BMD) was measured only at 3 and 6 months and 1, 2 and 3 years after transplantation. At baseline there was no difference in age or sex ratio, but prevalence in post-menopausal women was higher in group 1 (6.9% versus 1.2%). Duration on dialysis was comparable but prevalence of interstitial and undetermined nephropathies was higher in group 1. Baseline serum concentrations of PTH, Ca and P were comparable in both groups. After transplantation, plasma creatinine decreased to comparable levels in both groups. Immunosuppression by triple therapy was more prevalent in group 2, so that cumulative dose of steroid was higher in group 1, especially at 1 month because of higher incidence of acute rejections (51% versus 13%). Mean intact PTH levels decreased in both groups, from 18 pmol/l to 8.4 and 7.9 at 3 years, but the decrease was significantly greater with alfacalcidol at 6 and 12 months. At 3 months, BMD were comparable at both sites. From 3 months to 3 years after kidney transplantation, mean lumbar spine BMD significantly increased from 0.963 to 1.054 g/cm(2) in group 1, whereas there was no significant decrease (1.048 to 1.006 g/cm(2)) in group 2, the difference in changes being significant ( P<0.05). Femoral neck BMD was not significantly increased in either group (0.932 to 0.993 g/cm(2) in group 1, and 0.850 to 0.907 g/cm(2) in group 2). Expressed as percentages, these changes were +9.4% and -4% for lumbar BMD and +6.5% and +6.7% for femoral neck, for groups 1 and 2, respectively. Prevalence of osteopenia was not significantly lower at 3 years in group 1 (45% and 51%) than in group 2. During the follow-up period, osteonecrosis was diagnosed in six patients (3.8%) in group 1 and in nine (11%) in group 2. In conclusion, alfacalcidol compared to CaCO3 supplement suppressed hyperparathyroidism more rapidly and strongly. In spite of higher osteopenia risk in the CaCO3 group, lumbar BMD increase was greater and incidence of osteonecrosis higher in this group, suggesting better bone protection with CaCO3 than with alfacalcidol.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Osteoporosis International. - 14 : 5 (2003), p. 412-417. -
További szerzők:Asztalos László (1951-) (sebész) Kincses Zsolt (1961-) (orvos) Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Lőcsey Lajos (1946-2013) (belgyógyász, nephrológus) Balázs György (1933-) (sebész) Lukács Géza (1941-) (sebész)
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3.

001-es BibID:BIBFORM035368
035-os BibID:WOS:000221453600189
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Examination of the effect of dietary habits on bone mineral density inhealthy men aged 15 to 49 years living in the city of Debrecen (M341) / H. P. Bhattoa, Á. Balogh
Dátum:2007
ISSN:0937-941X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Endocrinology & Metabolism
egyetemen (Magyarországon) készült közlemény
Megjelenés:Journal of Bone and Mineral Research. Supplementum. - 22 : Suppl. 1 (2007), p. S197. -
További szerzők:Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos)
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4.

001-es BibID:BIBFORM035324
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:The effect of 1-year transdermal estrogen replacement therapy on bone mineral density and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus patients : a randomized, double-blind, placebo-controlled trial / H. P. Bhattoa, P. Bettembuk, A. Balogh, Gy. Szegedi, E. Kiss
Dátum:2004
ISSN:0937941X
Megjegyzések:We studied the effect of 1-year transdermal estrogen replacement therapy (ERT) on bone mineral density (BMD) and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus (SLE) patients in a randomized, double-blind, placebo-controlled trial. SLE patients were randomly allocated to treatment (estradiol; 50 ??g transdermal 17??-estradiol; n = 15) or placebo (n = 17) group. Both groups received 5 mg continuous oral medroxyprogesterone acetate, 500 mg calcium and 400 IU vitamin D3, L1-L4 spine (LS), left femur and total hip BMD were measured at baseline and at 6 and 12 months. Serum osteocalcin (OC) and degradation products of C-terminal telopeptides of type-I collagen (CTx) levels were measured at baseline and 3, 6, 9, and 12 months. There was a significant difference in the percentage change of LS BMD at 6 months between the two groups (103.24 ?? 3.74% (estradiol group) vs 98.99 ?? 3.11% (placebo group); P &lt; 0.005). There was a significant decrease within the estradiol group in the CTx levels between baseline and all subsequent visits (P &lt; 0.05). There was no significant difference in SLE disease activity index, Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) damage index and corticosteroid dose during the study period, Transdermal estradiol may prevent bone loss in postmenopausal SLE women at the lumbar spine and femur, with no increase in disease activity among postmenopausal SLE women receiving transdermal ERT. The high dropout rate (8/15) leads us to the conclusion that efficacy of HRT in a high-risk group such as SLE women can be attained only in a small number of patients, provided all inclusion/exclusion criteria are strictly adhered to.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Biochemical markers of bone turnover
Bone mineral density
Osteopenia
Postmenopausal Systemic lupus erythematosus
Transdermal estrogen replacement therapy
biological marker
calcium
carboxy terminal telopeptide
collagen type 1
corticosteroid
estradiol
medroxyprogesterone acetate
osteocalcin
placebo
vitamin D
adult
aged
article
bone density
bone mineral
bone turnover
carboxy terminal sequence
clinical trial
controlled clinical trial
controlled study
disease activity
double blind procedure
drug effect
drug efficacy
estrogen therapy
female
femur
hip
human
lumbar spine
medical society
osteolysis
osteopenia
postmenopause
priority journal
prophylaxis
protein blood level
randomization
randomized controlled trial
systemic lupus erythematosus
Administration, Cutaneous
Adult
Aged
Biological Markers
Bone Density
Bone Remodeling
Double-Blind Method
Estradiol
Estrogen Replacement Therapy
Female
Femur Neck
Hip Joint
Humans
Lumbar Vertebrae
Lupus Erythematosus, Systemic
Middle Aged
Osteoporosis, Postmenopausal
egyetemen (Magyarországon) készült közlemény
Megjelenés:Osteoporosis International. - 15 : 5 (2004), p. 396-404. -
További szerzők:Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Kiss Emese (1960-) (belgyógyász, immunológus)
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5.

001-es BibID:BIBFORM035323
035-os BibID:PMID:15205715
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in community dwelling postmenopausal Hungarian women / H. P. Bhattoa, P. Bettembuk, S. Ganacharya, A. Balogh
Dátum:2004
ISSN:0937941X
Megjegyzések:Hypovitaminosis D can result in low bone mass. The prevalence of hypovitaminosis D has public health implications, especially where data are lacking. Since diet and sunlight are the two souces of vitamin D, the results obtained in one geographical region may not be universally applicable. The aim of this study is to characterize the prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in community dwelling postmenopausal Hungarian women. We determined serum levels of 25-hydroxyvitamin D (25-OH-D), PTH, osteocalcin (OC), degradation products of C-terminal telopeptides of type-I collagen (CTx), dietary calcium intake and BMD at L2-L4 lumbar spine (LS) and femur neck (FN) in 319 randomly selected ambulatory postmenopausal women. The prevalence of hypovitaminosis D (serum 25-OH-D ?ë♯n 50 nmol/1) was 56.7%. On comparing patients with normal and low 25-OH-D, a significant difference was found in age (61.6 ?? 8.5 years versus 67.3 ?? 9.9 years; P &lt; 0.001), PTH (3.9 ?? 1.9 pmol/l versus 4.3 ?? 2.7 pmol/l; P &lt; 0.05), FN BMD (0.802 ?? 0.123 g/cm2 versus 0.744 ?? 0.125 g/cm2; P &lt; 0.001) and dietary calcium intake (714.4 ?? 199.4 g/day versus 607.9 ?? 233 g/day; P &lt; 0.001). Osteoporotic patients had a significantly lower 25-OH-D (37.6 ?? 19.8 nmol/l versus 56.4 ?? 24 nmol/l; P &lt; 0.001) and dietary calcium intake (519.2 ?? 244.5 mg/day versus 718.2 ?? 164.3 mg/day; P &lt; 0.001). After controlling for all other variables, 25-OH-D was found to be significantly associated with age, the average hours of sunshine in the 3 months prior to 25-OH-D level determination and dietary calcium intake (r2 = 0. 190; P &lt; 0.001). For FN BMD, significant independent predictors were age, body mass index, 25-OH-D and dietary calcium intake (r2 = 0.435; P &lt; 0.001). The prevalence of hypovitaminosis D during spring, summer, autumn and winter was 71%, 46.3%, 49.4% and 56.7%, respectively. There was significant seasonal variation in 25-OH-D, PTH, OC, calcium intake and FN BMD. There is a high prevalence of hypovitaminosis D in healthy postmenopausal Hungarian women, and FN BMD is associated with serum 25-OH-D and dietary calcium intake.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Biochemical markers of bone turnover
Bone mineral density
Hypovitaminosis D
Postmenopausal
Seasonal variation
25 hydroxyvitamin D
calcium
carboxy terminal telopeptide
collagen type 1
osteocalcin
parathyroid hormone
vitamin D
adult
aged
article
autumn
bone mass
bone metabolism
bone turnover
calcium intake
community
controlled study
dietary intake
female
femur neck
geographic distribution
human
Hungary
lumbar spine
major clinical study
osteoporosis
postmenopause
prevalence
priority journal
public health
seasonal variation
spring
summer
sunlight
vitamin D deficiency
winter
Adult
Aged
Aged, 80 and over
Biological Markers
Bone and Bones
Bone Density
Calcium
Collagen
Collagen Type I
Diet
Female
Femur Neck
Humans
Hungary
Middle Aged
Osteocalcin
Parathyroid Hormone
Peptides
Postmenopause
Prevalence
Seasons
Vitamin D
Vitamin D Deficiency
egyetemen (Magyarországon) készült közlemény
Megjelenés:Osteoporosis International. - 15 : 6 (2004), p. 447-451. -
További szerzők:Bettembuk Péter Ganacharya, Sanjay Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos)
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6.

001-es BibID:BIBFORM035054
035-os BibID:PMID:22422303
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in healthy Hungarian men over 50 years of age : the HunMen Study / H. P. Bhattoa, E. Nagy, C. More, J. Kappelmayer, A. Balogh, E. Kalina, P. Antal-Szalmas
Dátum:2013
ISSN:0937-941X
Megjegyzések:This study reports a high prevalence of hypovitaminosis D and low bone mineral density (BMD) in a healthy Hungarian male cohort over 50 years of age. Men with 25-hydroxyvitamin D levels of <75 nmol/L had a significantly higher 10-year hip and major osteoporotic fracture probability using the country-specific fracture risk assessment (FRAX) algorithm. INTRODUCTION: The aim of this study is to characterize the prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in healthy Hungarian men over 50 years of age. METHODS: We determined levels of 25-hydroxyvitamin D (25-OH-D), PTH, osteocalcin (OC), C-terminal telopeptides of type-I collagen (CTX-I), procollagen type 1 amino-terminal propeptide (PINP), BMD at L1-L4 (LS) and femur neck (FN), daily dietary calcium intake, and the 10-year probability of hip fracture and a major osteoporotic fracture using the country-specific FRAX algorithm in 206 randomly selected ambulatory men. RESULTS: The mean (range) age of the volunteers was 60 (51-81) years. The prevalence of hypovitaminosis D (25-OH-D, <75 nmol/L) was 52.9%. The mean (range) FRAX hip fracture and FRAX major osteoporotic fracture was 0.8% (0-9.4%) and 3.8% (1.7-16%), respectively. On comparing the vitamin D sufficient to the insufficient group, there was a statistically significant difference between the FRAX hip fracture and FRAX major osteoporotic fracture indexes. There was significant seasonal variation in the vitamin D levels; the lowest levels were measured in winter and the highest in summer. CONCLUSIONS: A high prevalence of hypovitaminosis D and low BMD were observed in the studied Hungarian male population. This is the first study reporting higher 10-year hip and major osteoporotic fracture probability using the country-specific FRAX algorithm in individuals with hypovitaminosis D.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Molekuláris Medicina
Megjelenés:Osteoporosis International. - 24 : 1 (2013), p. 179-186. -
További szerzők:Nagy E. Móré Csaba (1971-) (szülész-nőgyógyász) Kappelmayer János (1960-) (laboratóriumi szakorvos) Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Kalina Edit (1971-) (laboratóriumi analitikus) Antal-Szalmás Péter (1968-) (laboratóriumi szakorvos)
Pályázati támogatás:TÁMOP-4.2.1/B-09/1/KONV-2010-0007
TÁMOP
Celluláris hematológia - immunológia
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elektronikus változat
DOI
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7.

001-es BibID:BIBFORM084824
Első szerző:Cavalier, Etienne
Cím:European Biological Variation Study (EuBIVAS) : within- and between-subject biological variation estimates of [béta]-isomerized C-terminal telopeptide of type I collagen ([béta]-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein - a cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism / Cavalier E., Lukas P., Bottani M., Aarsand A. K., Ceriotti F., Coşkun A., Díaz-Garzón J., Fernàndez-Calle P., Guerra E., Locatelli M., Sandberg S., Carobene A., European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation, IOF-IFCC Committee for Bone Metabolism
Dátum:2020
ISSN:0937-941X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Osteoporosis International. - 31 : 8 (2020), p. 1461-1470. -
További szerzők:Lukas, Pierre Bottani, M. Aarsand, A. K. Ceriotti, F. Coşkun, A. Díaz-Garzón, J. Fernàndez-Calle, P. Guerra, E. Locatelli, M. Sandberg, Sverre Carobene, Anna Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) EFCC Laboratory Medicine Working Group on Biological Variation IFCC-IOF Joint Committee for Bone Metabolism
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8.

001-es BibID:BIBFORM077421
035-os BibID:(WoS)000451026600009 (Scopus)85052835741
Első szerző:Halasi Andrea (orvos)
Cím:Tight control : a new therapeutic strategy in the management of osteoporotic patients / A. Halasi, G. Kincse, J. Varga, J. Kéri, J. Gaál
Dátum:2018
ISSN:0937-941X
Megjegyzések:BMD changes in patients under tight control (monitored at 3-month intervals with adjustment of therapy guided by bone turnover markers) and routine management (controlled once a year) were compared. After 1 year, the femoral neck BMD increased significantly in the tight control compared to the routine management group. INTRODUCTION: We intended to ascertain whether tight control (i.e., follow-up visits and bone turnover markers/BTM/and parathyroid hormone/PTH/monitoring at 3-month intervals) strategy achieves a statistically greater increase in bone mineral density over the observation period than standard follow-up care (i.e., bone densitometry at 1-year intervals, without BTM monitoring). METHODS: We studied involutional osteoporotic patients newly enrolled into chronic care. One hundred and eleven patients underwent tight control, while another 113 received routine treatment (with follow-up visits scheduled at >?1-year intervals). We compared the changes in bone mineral density reflected by the results of bone mineral density (BMD) measurements of the lumbar spine and of the left femoral neck. Statistical analyses were performed with version 22 of the SPSS software package. RESULTS: In the group of patients under tight control, baseline and follow-up median BMD values were 0.842/0.881 g/cm2 at the L1-4 vertebrae and 0.745/0.749 g/cm2 at the femoral neck. In the group under routine care, the corresponding values were 0.903/0.915 g/cm2 and 0.742/0.72 g/cm2, respectively. The relative changes of the bone mineral density of the femoral neck was significantly (p?=?0.041) higher in patients under tight control than in those receiving routine care; however, BMD changes in the lumbar spine were not statistically different. CONCLUSION: Our findings suggest that adopting tight control as a new therapeutic strategy might be justified in the osteoporosis management. In fact, a greater improvement of BMD can be achieved by treatment according to these principles.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Osteoporosis
Strategy
Tight control
Treatment
Megjelenés:Osteoporosis International. - 29 : 12 (2018), p. 2677-2683. -
További szerzők:Kincse Gyöngyvér (1970-) (orvos) Varga József (1955-) (fizikus) Kéri Judit Gaál János (1965-) (reumatológus, belgyógyász)
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9.

001-es BibID:BIBFORM091551
Első szerző:Hamar Attila Béla (általános orvos)
Cím:Effects of one-year tofacitinib therapy on bone metabolism in rheumatoid arthritis / Hamar A., Szekanecz Z., Pusztai A., Czókolyová M., Végh E., Pethő Z., Bodnár N., Gulyás K., Horváth Á., Soós B., Bodoki L., Bhattoa H. P., Nagy G., Tajti G., Panyi G., Szekanecz É., Domján A., Hodosi K., Szántó S., Szűcs G., Szamosi S.
Dátum:2021
ISSN:0937-941X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Osteoporosis International. - 32 : 8 (2021), p. 1621-1629. -
További szerzők:Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Karancsiné Pusztai Anita (1989-) (tudományos segédmunkatárs) Czókolyová Mónika (1993-) (molekuláris biológus) Végh Edit (1978-) (reumatológus, belgyógyász) Pethő Zsófia (1981-) (reumatológus, immunológus) Bodnár Nóra (1980-) (reumatológus) Gulyás Katalin (reumatológus) Horváth Ágnes (1985-) (reumatológus) Soós Boglárka (1988-) (általános orvos) Bodoki Levente (1986-) (PhD hallgató) Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Nagy Gábor (1974-) (laboratóriumi szakorvos, laboratóriumi hematológus és immunológus) Tajti Gábor (1988-) (gyógyszerész, biofizikus, sejtbiológus) Panyi György (1966-) (biofizikus) Szekanecz Éva (1968-) (onkológus szakorvos) Domján Andrea (1979-) (reumatológus) Hódosi Katalin Szántó Sándor (1968-) (belgyógyász, reumatológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Szamosi Szilvia (1975-) (belgyógyász, reumatológus)
Pályázati támogatás:TAMOP4.2.4.A/2-11/1-2012-0001
TÁMOP
GINOP-2.3.2-15-2016-00015
GINOP
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10.

001-es BibID:BIBFORM068611
Első szerző:Jakab Éva
Cím:Standardizing 25-hydroxyvitamin D data from the HunMen cohort / E. Jakab, E. Kalina, Z. Petho, Z. Pap, A. Balogh, W. B. Grant, H. P. Bhattoa
Dátum:2017
ISSN:0937-941X
Megjegyzések:Summary Standardization of 25-hydroxyvitamin D (25OHD)values is still a challenge.We propose standardization by correctionof the measured 25OHD values using the linear regressionbias from the National Institute of Standards andTechnology (NIST) ♭total' target values reported by VitaminD External Quality Assessment Scheme (DEQAS). Our approachcould perhaps be a practical solution to the anomalysurrounding non-standardized 25OHD values.Introduction Standardization of 25OHD values is still a challenge.We propose standardization by correction of the measured25OHD values using the linear regression equation derivedfrom the analysis of relationship between total 25OHDvalues measured by the methodology used by the laboratoryand the NIST total target values (TV) reported by the DEQASfor all 5 of the DEQAS samples in a given survey.Methods We applied our approach to standardize total25OHD values of the HunMen cohort.Results All 206 samples for the HunMen cohort were evaluatedusing the automated Liaison DiaSorin total 25OHDchemiluminescence immunoassay (CLIA). The timing ofthese measurements coincided with that of the October 2015DEQAS survey using samples 481 to 485. Following standardization,the mean total 25OHD changed from 53 to62 nmol/L and the prevalence of hypovitaminosis D(<75 nmol/L) decreased significantly from 84 to 72%.Conclusion A simple approach readily applicable at the routinediagnostic laboratory could perhaps be a practical solutionto the anomaly surrounding non-standardized 25OHD values
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
25-Hydroxyvitamin D
DEQAS
HunMen
Standardization
Megjelenés:Osteoporosis International. - 28 : 5 (2017), p. 1653-1657. -
További szerzők:Kalina Edit (1971-) (laboratóriumi analitikus) Pethő Zsófia (1981-) (reumatológus, immunológus) Pap Zoltán Domokos (1973-) Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Grant, William B. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos)
Internet cím:DOI
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11.

001-es BibID:BIBFORM035369
035-os BibID:WOS:000221453600155
Első szerző:Mező T.
Cím:Environmental determinants of bone mineral density : results from the Hungarian osteoporosis risk assessment (HORA) study / Mezo, T., Tabak, A. G., Bhattoa, H. P., Lakatos, P.
Dátum:2004
ISSN:0937-941X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Endocrinology & Metabolism
egyetemen (Magyarországon) készült közlemény
Megjelenés:Osteoporosis International 15 (2004), p. S50-S50. -
További szerzők:Tabák Ádám G. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Lakatos P.
Borító:

12.

001-es BibID:BIBFORM035330
Első szerző:Móré Csaba (szülész-nőgyógyász)
Cím:The effects of pregnancy and lactation on bone mineral density / C. More, P. Bettembuk, H. P. Bhattoa, A. Balogh
Dátum:2001
ISSN:0937-941X
Megjegyzések:We performed a prospective study of bone mineral density (BMD) in 38 women during their first full-term pregnancy until 12 months postpartum. BMD measurements at lumbar spine [L2-L4 (LS)] and forearm [distal 33% (RD) and ultradistal (RUD) region of the radius] were made within 3 months before conception, after delivery, and at 6 and 12 months postpartum. In mid-pregnancy the DXA examination was carried out only at the forearm. Patients were grouped according to duration of lactation as group I, II or III (0-1, 1-6, 6-12 months respectively). During pregnancy there was a significant difference between baseline and delivery (p<0.001) in the LS, RUD and RD BMD values. In group I there was no statistically significant difference in LS BMD between visits following pregnancy. The RUD BMD loss was recovered by 6 months postpartum (PP6). Group II showed continuous bone loss from delivery until PP6 at LS and RUD. In group III the LS BMD loss continued throughout the lactation period. The RUD BMD dropped (4.9%) until PP6 then increased by 3.0% as measured at 12 months postpartum (PP12). There was no significant change in RD BMD in any of three groups during lactation. At LS bone loss between delivery and PP12 correlated well with the duration of lactation (r=-0.727; p<0.001). We suggest that calcium needed for fetal skeletal growth during pregnancy was gained from maternal trabecular and cortical sites and that calcium needed for infant growth during lactation was drawn mainly from the maternal trabecular skeleton in our patients. The effect of pregnancy and lactation on the maternal bone mass was spontaneously compensated after weaning.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Bone mineral density
Lactation
Pregnancy
adult
article
bone atrophy
bone density
bone growth
bone mineralization
calcium mobilization
controlled study
cortical bone
dual energy X ray absorptiometry
female
fetus growth
human
lactation
lumbar spine
pregnancy
priority journal
puerperium
trabecular bone
weaning
Adult
Bone Density
Densitometry, X-Ray
Female
Humans
Lactation
Pregnancy
Prospective Studies
egyetemen (Magyarországon) készült közlemény
Megjelenés:Osteoporosis International. - 12 : 9 (2001), p. 732-737. -
További szerzők:Bettembuk Péter Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos)
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DOI
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