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001-es BibID:BIBFORM035225
035-os BibID:(Scopus)84859963822 (WOS)000304850100018
Első szerző:Bányai Krisztián
Cím:Systematic review of regional and temporal trends in global rotavirus strain diversity in the pre rotavirus vaccine era: Insights for understanding the impact of rotavirus vaccination programs / Krisztián Bányai, Brigitta László, Jazmin Duque, A. Duncan Steele, E. Anthony S. Nelson, Jon R. Gentsch, Umesh D. Parashar
Dátum:2012
ISSN:0264-410X
Megjegyzések:Recently, two rotavirus vaccines have been recommended for routine immunization of infants worldwide. These vaccines proved efficacious during clinical trials and field use in both developing and developed countries, and appear to provide good protection against a range of rotavirus genotypes, including some that are not included in the vaccines. However, since conclusive data that the vaccines will protect against a wide variety of rotavirus strains are still lacking and since vaccines may exert some selection pressure, a detailed picture of global strain prevalence from the pre-rotavirus vaccine era is important to evaluate any potential changes in circulating strains observed after widespread introduction of rotavirus vaccines. Thus, we systematically reviewed rotavirus genotyping studies spanning a 12-year period from 1996 to 2007. In total, ?110,000 strains were genotyped from 100 reporting countries. Five genotypes (G1?G4, and G9) accounted for 88% of all strains, although extensive geographic and temporal differences were observed. For example, the prevalence of G1 strains declined from 2000 onward, while G3 strains re-emerged, and G9 and G12 strains emerged during the same period. When crude strain prevalence data were weighted by region based on the region's contribution to global rotavirus mortality, the importance of genotypes G1 and G9 strains that were more prevalent in regions with low mortality was reduced and conversely the importance of G8 strains that were more prevalent in African settings with greater contribution to global rotavirus mortality was increased. This study provides the most comprehensive, up-to-date information on rotavirus strain surveillance in the pre-rotavirus vaccine era and will provide useful background to examine the impact of rotavirus vaccine introduction on future strain prevalence.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
külföldön készült közlemény
Megjelenés:Vaccine. - 30 : Suppl. 1 (2012), p. 122-130. -
További szerzők:László Brigitta (1983-) (molekuláris biológus, mikrobiológus) Duque, Jazmin Steele, Amber Duncan Nelson, E. Anthony S. Gentsch, Jon R. Parashar, Umesh D.
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
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2.

001-es BibID:BIBFORM068952
Első szerző:DeVelasco, E. Alonso
Cím:Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines / DeVelasco E. Alonso, Dekker H. A. Th., Antal-Szalmás Péter, Jalink K. P., van Strijp Jos A. G., Verheul André F. M., Verhoef Jan, Snippe H.
Dátum:1994
ISSN:0264-410X
Megjegyzések:The adjuvant Quil A has been found to enhance theresponse of mice to pneumococcal polysaccharides,polysaccharide-protein conjugates and oligosaccharideproteinconjugates I 3. Quil A augments the antipolysaccharideimmunoglobulin M (IgM) and IgG titre,changes the IgG sub-isotype distribution, and increasesthe avidity of the antibodies specific for the nativepolysaccharide after immunization with synthetic oligosaccharideconjugates. Although Quil A has a minimaleffect on the magnitude of the antibody responseof rabbits to meningococcal oligosaccharide proteinconjugates, it influences the epitope specificity of theantibodies induced 4'5. In a previous study 1, no effect ofQuil A was observed on the secondary antibody responsein mice to pneumococcal polysaccharide 17F (PS)conjugated to keyhole limpet haemocyanin (KLH). Thiswas probably due to the strong immunogenicity of theconjugate itself. Therefore, in this paper we investigatedwhether Quil A would have an effect on the primaryantibody response to the same conjugate, and a similarlyprepared conjugate differing in PS/KLH ratio. Theprimary response in mice was assessed by (i) the levelsof PS-specific antibody induced, measured by anenzyme-linked immunosorbent assay (ELISA), (ii) theprotection against a lethal challenge with S. pneumoniae17F, and (iii) the in vitro opsonic activity of the antisera.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
monocytes
internalization
CD14
Megjelenés:Vaccine 12 : 15 (1994), p. 1419-1422. -
További szerzők:Dekker, H. A. Th. Antal-Szalmás Péter (1968-) (laboratóriumi szakorvos) Jalink, K. P. Strijp, Jos A. G., van Verheul, André F. M. Verhoef, Jan Snippe, H.
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM001909
Első szerző:Kardos Gábor (szakorvos, klinikai mikrobiológus)
Cím:DNA Fingerprinting Analysis of Breakthrough Outbreaks in Vaccine-Protected Poultry Stocks / Kardos Gábor, Turcsányi Ibolya, Bistyák Andrea, Nagy József, Kiss István
Dátum:2007
Megjegyzések:We report recurrent outbreaks of Yersinia pseudotuberculosis conjunctivitis in ducks and of fowl cholera in geese, occurring in stocks previously vaccinated with inactivated autogenous vaccines. Enterobacterial repetitive intergenic consensus sequence-based PCR and pulsed-field gel electrophoresis indicated reinfection with a new Y. pseudotuberculosis strain and vaccine evasion by the same Pasteurella multocida strain.
Tárgyszavak:Agrártudományok Állatorvosi tudományok idegen nyelvű folyóiratközlemény külföldi lapban
DNA Fingerprinting
Megjelenés:Clinical and Vaccine Immunology. - 14 : 12 (2007), p. 1649-1651. -
További szerzők:Turcsányi Ibolya Bistyák Andrea Nagy József (agráros) Kiss István (mikrobiológus)
Internet cím:elektronikus változat
DOI
elektronikus változat
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4.

001-es BibID:BIBFORM010924
Első szerző:Papp Mária (belgyógyász, gasztroenterológus)
Cím:Evaluation of the Combined Application of Ethanol-Fixed and formaldehyde-fixed neutrophil substrates for identifying atypical perinuclear antineutrophil cytoplasmic antibodies in inflammatory bowel disease / Maria Papp, Istvan Altorjay, Gabriella Lakos, Judit Tumpek, Sandor Sipka, Tamas Dinya, Karoly Palatka, Gabor Veres, Miklos Udvardy, Peter Laszlo Lakatos
Dátum:2009
ISSN:1556-6811 (Print)
Megjegyzések:No clear guidelines for indirect immunofluorescence (IIF) detection and interpretation of antineutrophil cytoplasmic antibodies (ANCA) have been proposed for inflammatory bowel diseases (IBD). We evaluated the reliability of the combined use of ethanol- and formalin-fixed neutrophil substrates to identify atypical perinuclear ANCA (P-ANCA) by IIF under routine laboratory circumstances. A total of 204 IBD patients were assessed with four different fluorescent substrates in two distinct laboratories. Antibodies against myeloperoxidase, proteinase-3, and other specific granule proteins (elastase, lactoferrin, cathepsin G, lysozyme, and bactericidal permeability-increasing protein) were measured by an enzyme-linked immunosorbent assay. The combined application of ethanol- and formalin-fixed slides to detect atypical P-ANCA resulted in a lack of agreement between assays ( K, <0.39) in the interassay study and moderate agreement in the interobserver study (K, 0.42). After atypical and typical P-ANCA patterns were combined, the consensus improved greatly. A total of 26.9% of patients were P-ANCA positive by at least two tests (44.3% of ulcerative colitis [UC] and 13.1% of Crohn's disease [CD] patients; P < 0.0001), while overall ANCA positivity was 22.5% to 34.8%. The combined application of ethanol-fixed and formaldehyde-fixed neutrophil substrates did not facilitate differentiation between P-ANCA and atypical P-ANCA, and the results were not consistent when substrates from different sources were used. Combining all P-ANCA ensures the highest sensitivity and specificity in differentiating UC from CD.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Clinical and Vaccine Immunology. - 16 : 4 (2009), p. 464-470. -
További szerzők:Altorjay István (1954-) (belgyógyász, gasztroenterológus, onkológus) Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Tumpek Judit (1944-) (orvosi laboratóriumi szakorvos) Sipka Sándor (1945-) (laboratóriumi szakorvos) Dinya Tamás (1974-) (sebész szakorvos, onkológus szakorvos) Palatka Károly (1961-) (belgyógyász, gasztroenterológus) Veres Gábor (1969-2020) (csecsemő- és gyermekgyógyász, gasztroenterológus) Udvardy Miklós (1947-) (belgyógyász, haematológus) Lakatos Péter (Semmelweis Egyetem)
Internet cím:DOI
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