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1.

001-es BibID:BIBFORM117873
Első szerző:Al-Smadi, Mohammad Walid
Cím:Minor micro-rheological alterations in the presence of an artificial saphenous arteriovenous shunt, as an arteriovenous malformation model in the rat / Mohammad Walid Al-Smadi, Laszlo Adam Fazekas, Adam Varga, Adam Attila Matrai, Siran Aslan, Anas Beqain, Mustafa Qais Muhsin Al-Khafaji, Barbara Bedocs-Barath, Laszlo Novak, Norbert Nemeth
Dátum:2024
ISSN:1386-0291
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Clinical Hemorheology And Microcirculation. - [Epub ahead of print] (2024). -
További szerzők:Fazekas László Varga Ádám Mátrai Ádám Attila (1997-) (klinikai laboratóriumi kutató) Aslan, Siran Beqain, Anas Al-Khafaji, Mustafa Qais Muhsin Baráth Barbara (1993-) (tudományos segédmunkatárs) Novák László (1964-) (idegsebész) Németh Norbert (1975-) (kutatóorvos)
Pályázati támogatás:K-139184
OTKA
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2.

001-es BibID:BIBFORM118901
035-os BibID:(WoS)001152827800001 (Scopus)85187190105
Első szerző:Csiki Emese (onkoradiológus)
Cím:Stereotactic body radiotherapy in lung cancer : a contemporary review / Csiki Emese, Simon Mihály, Papp Judit, Barabás Márton, Mikáczó Johanna, Gál Kristóf, Sipos Dávid, Kovács Árpád
Dátum:2024
ISSN:1219-4956 1532-2807
Megjegyzések:The treatment of early stage non-small cell lung cancer (NSCLC) has improved enormously in the last two decades. Although surgery is not the only choice, lobectomy is still the gold standard treatment type for operable patients. For inoperable patients stereotactic body radiotherapy (SBRT) should be offered, reaching very high local control and overall survival rates. With SBRT we can precisely irradiate small, well-defined lesions with high doses. To select the appropriate fractionation schedule it is important to determine the size, localization and extent of the lung tumor. The introduction of novel and further developed planning (contouring guidelines, diagnostic image application, planning systems) and delivery techniques (motion management, image guided radiotherapy) led to lower rates of side effects and more conformal target volume coverage. The purpose of this study is to summarize the current developments, randomised studies, guidelines about lung SBRT, with emphasis on the possibility of increasing local control and overall rates in "fit," operable patients as well, so SBRT would be eligible in place of surgery.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Pathology & Oncology Research. - 161 (2024), p. 1-13. -
További szerzők:Simon Mihály Papp Judit (1971-) (onkoradiológus) Barabás Márton Mikáczó Johanna Gál Kristóf (1994-) (orvos) Sipos Dávid Kovács Árpád (1979-) (onkoradiológus, klinikai onkológus)
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3.

001-es BibID:BIBFORM119727
035-os BibID:(Scopus)85188913449 (WoS)001191907100001
Első szerző:Gulyás Anita
Cím:Case report : targeted treatment strategies for Erdheim-Chester disease / Anita Gulyás, László Imre Pinczés, János Mátyus, Edit Végh, Judit Bedekovics, Judit Tóth, Sándor Barna, Zsolt Hunya, Imre Lőrinc Szabó, Annamária Gazdag, Árpád Illés, Ferenc Magyari
Dátum:2024
ISSN:2234-943X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Oncology. - 14 (2024), p. 1-6. -
További szerzők:Pinczés László Imre (1990-) (általános orvos) Mátyus János (1957-) (belgyógyász, nephrológus) Végh Edit (1978-) (reumatológus, belgyógyász) Bedekovics Judit (1986-) (orvos) Tóth Judit (1958-) (onkológus szakorvos) Barna Sándor (1982-) (kutató orvos) Hunya Zsolt (1980-) (ortopéd és baleseti sebész) Szabó Imre Lőrinc (1987-) (általános orvos) Gazdag Annamária (1979-) (belgyógyász) Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Magyari Ferenc (1985-) (belgyógyász, hematológus)
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4.

001-es BibID:BIBFORM117861
Első szerző:Herman Tünde (orvos)
Cím:Hashimoto's thyroiditis negatively influences ICSI outcome in euthyroid women on T4 substitution therapy; a retrospective study / Tünde Herman, Péter Török, Antonio Simone Laganà, Vito Chiantera, Renato Venezia, Attila Jakab
Dátum:2024
ISSN:0378-7346
Megjegyzések:Abstract Objective: To analyze the impact of thyroid autoimmunity (TAI) on reproductive outcome parameters of ICSI cycles as compared to TAI negative ICSI cycles. Design: In this single IVF center retrospective study 86 infertile women with elevated TPOAb or TGAb levels, but euthyroid after thyroxine replacement (study group), were compared to 69 female patients with no thyroid abnormalities (controls). Following ICSI treatment fertilization rate (FR), clinical pregnancy rate (CPR), miscarriage rate (MR) and live birth rate (LBR) were analyzed. Materials, Setting, Methods: All subjects with various infertility factors were treated with ICSI in university based IVF center. Patients in the study group received thryroxine replacement and were euthyreoid at IVF treatment. Before the IVF cycles endocrinological parameters were uniformly assessed: thyroid function and antibodies, reproductive hormones (AMH, FSH, LH, E2, PRL, testosterone, DHEAS, 17-OHP, AD) and OGTT (0-60-120 min glucose and insulin). Following descriptive comparison of laboratory parameters, age adjusted analyses of FR, CPR, MR and LBR were performed. Results: TAI positive women were older (mean age 35.31?4.95 vs. 32.15?4.87 years; p=0.002), had higher FSH (8.4?3.4 vs. 7.4?2.32 U/L; p=0.024), higher E2 (53.94?47.61 vs. 42.93?18.92 pg/ml; p=0.025) levels, while AMH (2.88?2.62 vs. 3.61?1.69 ng/ml; p=0.0002) was lower. There were no differences in TSH levels (1.64?0.96 vs. 1.66?0.65 uIU/ml; p=0.652) between the two groups. FT3 (2.63?0.58 vs. 2.98?0.55 pg/ml; p=0.002) was lower and FT4 (1.3?0.29 vs. 1.13?0.21 ng/dl; p=0.0002) was higher in the TAI positive group, reflecting clinically irrevelant differences. Egg cell counts (6?3.8 vs. 7.5?3.95; p=0.015) were lower in TAI and remained so following age adjustment. Although the overall ICSI FR did not differ (62.9 % vs. 69.1 %, p=0.12), it was lower for patients under 35 with TAI showing decreasing differences in line with age. The CPR (36.04 % vs. 69.56 %; p<0.001), LBR (23.25 % vs. 60.86 %; p<0.001) were lower, the MR (35.48 % vs. 12.5 %; p=0.024) was higher in the TAI group and these differences remained after age adjustment. Limitations: Since the higher age of the study group may interfere with the effect of TAI, age adjustment calculations were necessary to perform to eliminate this confounding factor. Conclusion: Despite optimal thyroid supplementation in clinical or subclinical hypothyreoidism, the presence of TAI negatively influences clinical pregnancy rate and is connected to a higher miscarriage rate, thus resulting in a lower live birth rate after ICSI. Decreased fertilization rate with ICSI in TAI patients may also contribute to poorer outcomes, especially in younger women.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
IVF
ICSI
Hashimoto thyreoiditis
Megjelenés:Gynecologic And Obstetric Investigation. - [Epub ahead of print] (2024). -
További szerzők:Török Péter (1975-) (szülész-nőgyógyász) Laganà, Antonio Simone Chiantera, Vito Venezia, Renato Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus)
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5.

001-es BibID:BIBFORM118467
035-os BibID:(scopus)85184558879 (wos)001157742800001
Első szerző:Kenyeres Anna
Cím:Age and lymphocyte/monocyte ratio as prognostic factors for autologous transplantation in the treatment of patients with follicular lymphoma / Kenyeres Anna, Kiss Evelin, Simon Zsófia, Illés Árpád, Jóna Ádám
Dátum:2024
ISSN:0300-0605
Megjegyzések:Objective: Follicular lymphoma (FL) is an indolent, lymphoproliferative disease of B-cell origin that has a heterogeneous disease course with varying outcomes. Certain patients may undergo autologous stem cell transplantation. We investigated the outcome of autologous stem cell transplantation in patients with FL. Methods: Patients who received autologous stem cell transplantation at the University of Debrecen's Department of Hematology between 2004 and 2021 were retrospectively analyzed. The overall survival (OS) and progression-free survival (PFS) after transplantation of patients with FL were examined. Prognostic factors that may influence the course of the disease were chosen. Results: Data were collected from 49 patients. OS was influenced only by age, whereas PFS was affected by age and the lymphocyte/monocyte ratio. The combination of age and lymphocyte/ monocyte ratio defined a patient population with a particularly unfavorable prognostic risk profile: patients over 47 years of age with a pre-transplant lymphocyte/monocyte ratio greater than or equal to 2.675. Conclusion: Age and lymphocyte/monocyte ratio were identified as useful prognostic factors for PFS in patients with FL following autologous stem cell transplantation.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Follicular lymphoma
autologous hematopoietic stem cell transplantation
lymphocyte/monocyte ratio
age
prognostic marker
overall survival
progression-free survival
Megjelenés:Journal of International Medical Research. - 52 : 2 (2024), p. 1-10. -
További szerzők:Kiss Evelin Simon Zsófia (1977-) (belgyógyász, haematológus) Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Jóna Ádám (1985-) (orvos)
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