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001-es BibID:BIBFORM005979
Első szerző:Hadházy Csaba (anatómus)
Cím:In vitro cartilage differentiation : modification of division cycle and effect of some polyanions / Hadházy, C., Szöllösi, J., László, M. B.
Dátum:1983
Megjegyzések:A modification of division cell cycle under conditions of in vitro cartilage differentiation could be demonstrated. The frequency distribution of histograms showed that the G1 cells represented 50% of total cells number at zero time (i.e. in suspension before inoculation), 69% on day 2 and about 90% in following period of days 4, 6 and 14. Dextran sulfate and hyaluronic acid produced a conspicuous inhibition and the chondroitin sulfate as well as heparin exerted a moderate inhibiting effect on the cell proliferation.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
analysis
Animal
Cartilage
Cell Cycle
Cell Differentiation
Cell Division
Chick Embryo
Chondroitin Sulfates
cytology
Dextrans
Dna
drug effects
Heparin
Hyaluronic Acid
In Vitro
Mitosis
pharmacology
Sulfates
Support,Non-U.S.Gov't
Time Factors
Megjelenés:Acta Histochemica. Supplementband. - 27 (1983), p. 285-288. -
További szerzők:Szöllősi János (1953-) (biofizikus) László Mária, B.
Internet cím:elektronikus változat
Borító:

2.

001-es BibID:BIBFORM005978
Első szerző:Hadházy Csaba (anatómus)
Cím:Modification of the cell cycle of limb bud mesenchyme during in vitro cartilage differentiation / Hadházy, C., Szöllősi, J.
Dátum:1983
Megjegyzések:A consistent chondrogenesis takes place in micro high-density cultures derived from limb mesenchymal cells of chick embryos of stages 23-24. Flow-cytometric measurements of DNA content showed that cells in the phase of G1 or G0 made up 51% of the dispersed cell suspensions. The proportion of these cells increased to 71% by the onset of cartilage differentiation in day-2 cultures. This ratio was 84% when the voluminous matrix formation began on the 4th day of culturing. Thereafter, it increased to 90% by the 6th day, and to 93% by the 14th day. The results suggest that cartilage differentiates from G0 mesenchymal cells of the limb. In our measurements, however, the G0 phase includes all non-proliferative cell population which have identical DNA content with G1 cells. Therefore, the G0 phase contains also an increasing number of chondroblasts and chondrocytes as the chondrogenesis proceeds.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
folyóiratcikk
Animal
Cartilage
Cell Cycle
Cell Differentiation
Cells,Cultured
Chick Embryo
cytology
Dna
Embryo
embryology
Extremities
Hungary
In Vitro
Interphase
Mesoderm
metabolism
Support,Non-U.S.Gov't
Time Factors
Megjelenés:Acta Biologica Hungarica. - 34 : 4 (1983), p. 407-414. -
További szerzők:Szöllősi János (1953-) (biofizikus)
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