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1.

001-es BibID:BIBFORM082343
Első szerző:La Rosa, Valentina L.
Cím:Quality of life in women with endometriosis : a narrative overview / Valentina Lucia La Rosa, Pasquale De Franciscis, Fabio Barra, Antonio Schiattarella, Peter Török, Mohsin Shah, Erbil Karaman, Tais Marques Cerentini, Federica Di Guardo, Giuseppe Gullo, Marco Ponta, Simone Ferrero
Dátum:2020
Megjegyzések:Endometriosis is a very complex condition and has a significant impact on the quality of life, psychological wellbeing and interpersonal relationships of affected women. Endometriosis symptoms progressively impair the woman's ability to carry out some daily activities and result in a perception of worsening health status and overall well-being. The impact of these symptoms has been only partially investigated, and further studies and clinical insights are needed to fully understand the extent of this condition. It has been shown that endometriosis is associated with considerable direct and indirect costs, comparable to those of major worldwide chronic diseases such as diabetes. In addition, endometriosis-related symptoms substantially interfere with the employment of affected women, resulting in many cases in several working days missed. In this scenario, the aim of this narrative review is to provide a general overview of the psychological and social impact of this disease, as well as the effects of different therapeutic options, on quality of life and general well-being.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Endometriosis
Treatments
Quality of life
Psychology
Anxiety
Depression
Megjelenés:Minerva Medica. - 111 : 1 (2020), p. 68-78. -
További szerzők:De Franciscis, Pasquale Barra, Fabio Schiattarella, Antonio Török Péter (1975-) (szülész-nőgyógyász) Shah, Mohsin Karaman, Erbil Marques Cerentini, Tais Di Guardo, Federica Gullo, Giuseppe Ponta, Marco Ferrero, Simone
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2.

001-es BibID:BIBFORM097395
Első szerző:Lőrincz Judit (általános orvos)
Cím:Hystero-salpingo scintigraphy for fallopian tubal patency assessment : results from a prospective study / Lörincz Judit, Vitale Salvatore Giovanni, Barna Sándor Kristóf, Dinkó Fanni, Riemma Gaetano, Herman Tünde, Nagyházi Orsolya, Lampé Rudolf, De Franciscis Pasquale, Török Péter
Dátum:2022
ISSN:1364-5706
Megjegyzések:Objective: To evaluate the diagnostic accuracy of a bygone method, hystero-salpingo-scintig- raphy (HSSG), for tubal patency assessment of infertile women. Material and methods: Prospective cohort study involving women in the infertility workup at the University of Debrecen, Hungary. Seventy infertile patients were scheduled to either basic dynamic HSSG, post-purge dynamic HSSG, or post-purge dynamic HSSG followed by SPECT/CT for reducing tracer contamination. The primary endpoint was the evaluation of the diagnostic accuracy of HSSG for the three methods. Results: During the basic dynamic group, the examination yielded a sensitivity of 87.5%, with a specificity of 71.7%, while positive and negative predictive values were 31.8%, and 97.4% respectively. Using post purge dynamic HSSG, it resulted in a sensitivity of 87.5%, a specificity of 88.7%, a positive predictive value of 53.8%, and a negative predictive value of 97.9%. Adding SPECT/CT to post-purge dynamic HSSG increased diagnostic accuracy with 100% sensitivity and 88.7% specificity, while positive and negative predictive values were 57.1% and 100%, respectively. Conclusion: HSSG is a non-invasive and well-tolerated technique for tubal patency. It could be used initially to predict tubal patency in case of infertility. Its diagnostic accuracy is higher when it is carried out by adding SPECT/CT to the post-purge dynamic method.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
infertility
tubal patency
fallopian tube
scintigraphy
SPECT
radionuclides
Megjelenés:Minimally Invasive Therapy & Allied Technologies. - 31 : 5 (2022), p. 797-802. -
További szerzők:Vitale, Salvatore Giovanni Barna Sándor (1982-) (kutató orvos) Dinkó Fanni Riemma, Gaetano Herman Tünde (1979-) (orvos) Nagyházi Orsolya Lampé Rudolf (1983-) (szülész-nőgyógyász) De Franciscis, Pasquale Török Péter (1975-) (szülész-nőgyógyász)
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3.

001-es BibID:BIBFORM100559
035-os BibID:(cikkazonosító)102350
Első szerző:Riemma, Gaetano
Cím:The role of hysteroscopy in reproductive surgery : today and tomorrow / Riemma Gaetano, Vitale Salvatore Giovanni, Manchanda Rahul, Rathore Aayushi, Török Péter, De Angelis Carlo, Urman Bulent, Sareri Marco Iraci, La Verde Marco, Carugno Jose, De Franciscis Pasquale, Tesarik Jan
Dátum:2022
ISSN:2468-7847
Megjegyzések:During the last decades, the number of couples with reproductive issues has substantially increased. Many different factors are implicated in reproductive failure, including uterine factors. Endometrial pathologies, such as endometrial polyps, hyperplasia, endometritis, and Mullerian anomalies, can also hinder embryo implantation. Hysteroscopy remains the gold standard for the evaluation and treatment of intrauterine pathology. Over the last few years, advances in hysteroscopic instrumentations and surgical techniques have significantly evolved, the refinement in technology, miniaturization of instruments, and improved image quality have rendered hysteroscopy a more patient and user-friendly procedure that has enhanced its use in reproductive medicine. Nowadays, hysteroscopy is essential in the evaluation and treatment of women with infertility. This article underscores the major technological breakthroughs achieved over the last few years with emphasis on the role of artificial intelligence, augmented reality, and 3D hysteroscopy, which can set new benchmarks in hysteroscopy applied to reproductive medicine.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Hysteroscopy
portable hysteroscope
tissue retrieval system
3D hysteroscopy
clinical pregnancy
IVF
Megjelenés:Journal of Gynecology Obstetrics and Human Reproduction. - 51 : 4 (2022), p. 1-5. -
További szerzők:Vitale, Salvatore Giovanni Manchanda, Rahul Rathore, Aayushi Török Péter (1975-) (szülész-nőgyógyász) De Angelis, Carlo Urman, Bulent Sareri, Marco Iraci La Verde, Marco Carugno, Jose De Franciscis, Pasquale Tesarik, Jan
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4.

001-es BibID:BIBFORM081628
Első szerző:Rizzo, Gianluca
Cím:Vitamin D and Gestational Diabetes Mellitus : is there a link? / Gianluca Rizzo, Simone Garzon, Michele Fichera, Marco Marzio Panella, Ursula Catena, Antonio Schiattarella, Pasquale de Franciscis, George Vilos, Jan Tesarik, Péter Török, Giuseppe Grosso
Dátum:2019
ISSN:2076-3921
Megjegyzések:Gestational diabetes mellitus (GDM) is a very common condition among pregnant women worldwide with important metabolic implications on the mother and the o spring. Vitamin D status has been suggested to potentially play a role in GDM risk with no documented consequences for the offspring. The purpose of this article was to review currently available evidence on the relationship between vitamin D and GDM. Current evidence shows an association between vitamin D blood levels and risk of GDM, despite heterogeneity of results across studies limit the conclusions. Moreover, data from randomized controlled trials is scarce and resulting in null findings. Among the limitations to be noted, improving the standardization of dosages, the characteristics of individuals in the sample, and the appropriate outcome measurement could provide a more effective approach in understanding the relationship between vitamin D and GDM. In conclusions, despite observational studies may suggest that adequate vitamin D levels may decrease the risk of GDM compared to deficiency status, evidence from clinical trials is inadequate to draft any definitive conclusion regarding its supplementation. Future better designed randomized clinical trials taking into account a more integrated approach could provide clearer and definitive data on the outcomes of such a multifactorial condition.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
vitamin D
gestational diabetes mellitus
pregnancy
nutrition
supplements
antenatal care
food fortification
Megjelenés:Antioxidants. - 8 : 11 (2019), p. 1-13. -
További szerzők:Garzon, Simone Fichera, Michele Panella, Marco Marzio Catena, Ursula Schiattarella, Antonio De Franciscis, Pasquale Vilos, George Tesarik, Jan Török Péter (1975-) (szülész-nőgyógyász) Grosso, Giuseppe
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5.

001-es BibID:BIBFORM119026
035-os BibID:(Scopus)85185787111
Első szerző:Vitale, Salvatore Giovanni
Cím:Risk of Endometrial Cancer in Asymptomatic Postmenopausal Women in Relation to Ultrasonographic Endometrial Thickness : Systematic Review and Diagnostic Test Accuracy Meta-analysis / Vitale Salvatore Giovanni, Riemma Gaetano, Haimovich Sergio, Carugno Jose, Pacheco Luis Alonso, Perez-Medina Tirso, Parry John Preston, Török Peter, Tesarik Jan, Corte Luigi Della, Cobellis Luigi, Sardo Attilio Di Spiezio, De Franciscis Pasquale
Dátum:2024
ISSN:0029-7828
Tárgyszavak:Orvostudományok Klinikai orvostudományok hozzászólás
folyóiratcikk
Megjelenés:Obstetrical & Gynecological Survey. - 79 : 2 (2024), p. 94-96. -
További szerzők:Riemma, Gaetano Haimovich, Sergio Carugno, Jose Pacheco, Luis Alonso Perez-Medina, Tirso Parry, John Preston Török Péter (1975-) (szülész-nőgyógyász) Tesarik, Jan Corte, Luigi Della Cobellis, Luigi Sardo, Attilio Di Spiezio De Franciscis, Pasquale
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6.

001-es BibID:BIBFORM110695
035-os BibID:(cikkazonosító)102588 (Scopus)85153232429 (WoS)000990464300001
Első szerző:Vitale, Salvatore Giovanni
Cím:Endometrial Biopsy : Indications, Techniques and Recommendations. An Evidence-Based Guideline for Clinical Practice / Vitale Salvatore Giovanni, Buzzaccarini Giovanni, Riemma Gaetano, Pacheco Luis Alonso, Sardo Attilio Di Spiezio, Carugno Jose, Chiantera Vito, Török Peter, Noventa Marco, Haimovich Sergio, De Franciscis Pasquale, Perez-Medina Tirso, Angioni Stefano, Lagana Antonio Simone
Dátum:2023
ISSN:2468-7847
Megjegyzések:This practice guideline provides updated evidence for the gynecologist who performs endometrial biopsy (EB) in gynecologic clinical practice. An international committee of gynecology experts developed the recommendations according to AGREE Reporting Guideline. An adequate tissue sampling is mandatory when performing an EB. Blind methods should not be first choice in patients with suspected endometrial malignancy. Hysteroscopy is the targeted-biopsy method with highest diagnostic accuracy and cost-effectiveness. Blind suction techniques are not reliable for the diagnosis of endometrial polyps. In low resources settings, and in absence of the capacity to perform office hysteroscopy, blind techniques could be used for EB. Hysteroscopic punch biopsy allows to collect only limited amount of endometrial tissue. grasp biopsy technique should be considered first choice in reproductive aged women, bipolar electrode chip biopsy should be preferred with hypotrophic or atrophic endometrium. EB is required for the final diagnosis of chronic endometritis. There is no consensus regarding which endometrial thickness cut-off should be used for recommending EB in asymptomatic postmenopausal women. EB should be offered to young women with abnormal uterine bleeding and risk factors for endometrial carcinoma. Endometrial pathology should be excluded with EB in nonobese women with unopposed hyperestrogenism. Hysteroscopy with EB is useful in patients with abnormal bleeding even without sonographic evidence of pathology. EB has high sensitivity for detecting intrauterine pathologies. In postmenopausal women with uterine bleeding, EB is recommended. Women with sonographic endometrial thickness > 4mm using tamoxifen should undergo hysteroscopic EB.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Hysteroscopy
Practical guidelines
Endometrium
Endometrial biopsy
Megjelenés:Journal of Gynecology Obstetrics and Human Reproduction. - 52 : 6 (2023), p. 1-7. -
További szerzők:Buzzaccarini, Giovanni Riemma, Gaetano Pacheco, Luis Alonso Sardo, Attilio Di Spiezio Carugno, Jose Chiantera, Vito Török Péter (1975-) (szülész-nőgyógyász) Noventa, Marco Haimovich, Sergio De Franciscis, Pasquale Perez-Medina, Tirso Angioni, Stefano Laganà, Antonio Simone
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7.

001-es BibID:BIBFORM103064
035-os BibID:(WoS)000911496500001 (Scopus)85136295331
Első szerző:Vitale, Salvatore Giovanni
Cím:Risk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness : systematic review and diagnostic test accuracy meta-analysis / Vitale Salvatore Giovanni, Riemma Gaetano, Haimovich Sergio, Carugno Jose, Pacheco Luis Alonso, Perez-Medina Tirso, Parry John Preston, Török Peter, Tesarik Jan, Della Corte Luigi, Cobellis Luigi, Di Spiezio Sardo Attilio, De Franciscis Pasquale
Dátum:2023
ISSN:0002-9378
Megjegyzések:Objective: To evaluate the risk of endometrial carcinoma (EC) and atypical endometrial hyperplasia (AEH) in asymptomatic postmenopausal women in relation to the endometrial thickness (ET) measured by transvaginal ultrasonography (TVS) stratified by threshold categories used for performing subsequent endometrial sampling and histologic evaluation. Data sources: MEDLINE, Scopus, ClinicalTrials.gov, Scielo, EMBASE, the Cochrane Library at the CENTRAL Register of Controlled Trials, LILACS, conference proceedings and international controlled trials registries were searched without temporal or geographical or language restrictions. Study eligibility criteria: Studies were selected if they had a cross-over design evaluating the risk for AEH and EC in postmenopausal asymptomatic women and calculated the diagnostic accuracy of TVS thresholds (at least 3.0 mm) confirmed by histopathological diagnosis. Study appraisal and synthesis methods: We conducted a systematic review and diagnostic test accuracy meta-analysis according to PRISMA-DTA and SeDATE guidelines. ET thresholds were grouped as follows: from 3.0 mm to 5.9 mm; between 6.0 and 9.9 mm; between 10.0 and 13.9 mm; and equal or greater than 14.0 mm. Quality assessment was performed using QUADAS-2 tool. Publication bias was quantified by Deek funnel plot test. Co-primary outcomes were risk for AEH or EC according to ET and diagnostic accuracy of each threshold group. Results: A total of 18 studies provided the data of 10,334 women who were all included in the final analysis. Overall, at an ET threshold of at least 3.0 mm, the risk for AEH or EC was increased three-fold relative to women below the cut-off (relative risk (RR) 3.77, 95% confidence interval (CI) 2.26 to 6.32, I2=74%). Similar degrees of risk were reported for thresholds between 3.0 and 5.9 mm (RR 5.08, 95% CI 2.26 to 11.41, I2=0%), 6.0 and 9.9 mm (RR 4.34, 95% CI 1.68 to 11.23, I2=0%), 10.0 and 13.9 mm (RR 4.11, 95% CI 1.55 to 10.87, I2=86%) and over 14.0 mm (RR 2.53, 95% CI 1.04 to 6.16, I2=78%) with no significant difference among subgroups (p=0.885). Regarding diagnostic accuracy, the pooled sensitivity decreased from thresholds below 5.9 mm (0.81, 95% CI 0.49 to 0.85) to above 14.0 mm (0.28 95% CI 0.18 to 0.40) Meanwhile, specificity increased from 0.70 (95% CI 0.61 to 0.78) for ET between 3.0 mm and 5.9 mm to 0.86 (95% CI 0.71 to 0.94) when the ET is 14.0 mm or greater. For 3.0-5.9 mm and 10.0-13.9 mm thresholds, the highest diagnostic odds ratio of 10 (95% CI 3 to 41) and 11 (95% CI 2 to 49), with an area under curve of 0.81 (95% CI 0.77 to 0.84) and 0.82 (95% CI 0.79 to 0.86) respectively were retrieved. The summary point analysis revealed that, compared to the other subgroups, the 3.0-5.9 mm cut off point was placed higher in the summary receiver operator curve space, indicating increased EC or AEH diagnosis using these cut-offs. Conclusions: Both low and high ET thresholds in postmenopausal asymptomatic women seem equally effective in detecting EC and AEH. However, although using a 3.0 to 5.9 mm cut off results in lower specificity, the offsetting improvement in sensitivity may justify using this cut off for further endometrial evaluation in patients with suspected endometrial malignancy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Atypical Endometrial Hyperplasia
Cut-off
Endometrial cancer
Endometrial thickness
Transvaginal ultrasonography
Megjelenés:American Journal Of Obstetrics And Gynecology. - 228 : 1 (2023), p. 22-35.e2. -
További szerzők:Riemma, Gaetano Haimovich, Sergio Carugno, Jose Pacheco, Luis Alonso Perez-Medina, Tirso Parry, John Preston Török Péter (1975-) (szülész-nőgyógyász) Tesarik, Jan Della Corte, Luigi Cobellis, Luigi Di Spiezio Sardo, Attilio De Franciscis, Pasquale
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8.

001-es BibID:BIBFORM089397
Első szerző:Vitale, Salvatore Giovanni
Cím:Hysteroscopy for Assessing Fallopian Tubal Obstruction : a Systematic Review and Diagnostic Test Accuracy Meta-analysis / Vitale Salvatore Giovanni, Carugno Jose, Riemma Gaetano, Török Péter, Cianci Stefano, De Franciscis Pasquale, Parry John Preston
Dátum:2021
ISSN:1553-4650
Megjegyzések:Objective To assess the diagnostic accuracy of hysteroscopy compared to laparoscopic chromopertubation for the detection of fallopian tubal obstruction. Data Sources An electronic search from inception to March 31, 2020 was performed in Medline, Scopus, EMBASE and the Cochrane Controlled Trials Register. Methods of Study Selection This diagnostic accuracy meta-analysis was conducted following PRISMA and SEDATE recommendations. A combination of the following MeSH terms and keywords was included in search strategy: "hysteroscopy[MeSH]", "tubal obstruction" "tubal patency", "tubal dysfunction", "tubal blockage". Quality assessment of included studies was conducted using the QUADAS-2 tool. Publication bias was evaluated by means of Deek funnel plot asymmetry test. The following outcomes were analyzed: diagnostic odds ratio (DOR), area under hierarchical summary receiver operating characteristic (HSROC) and area under receiver operating characteristic curve (AUROC), sensitivity, specificity, positive and negative likelihood ratio (PLR and NLR). Tabulation, Integration, and Results Six studies comparing hysteroscopy with laparoscopic chromopertubation were included in the meta-analysis. After pooling of all the studies, DOR was 43. Evaluated AUROC was 0.93, correlating with high diagnostic accuracy for the index test. Sensitivity and specificity were 88% and 85% respectively. Also, PLR and NLR were 5.88 and 0.16 respectively. Conclusion Hysteroscopic techniques are highly accurate and sensitive for detecting fallopian tubal obstruction. Interventional assessment enhances diagnostic accuracy relative to observational assessment as does the office setting relative to the operating room. Additional studies, along with refinement of the techniques, could facilitate the widespread use of hysteroscopic techniques for the detection of fallopian tube occlusion
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
hysteroscopy
infertility
tubal patency
tubal obstruction
chromopertubation
Megjelenés:Journal Of Minimally Invasive Gynecology. - 28 : 4 (2021), p. 769-778. -
További szerzők:Carugno, Jose Riemma, Gaetano Török Péter (1975-) (szülész-nőgyógyász) Cianci, Stefano De Franciscis, Pasquale Parry, John Preston
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