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001-es BibID:	BIBFORM048861
Első szerző:	Koukoulomati, A.
Cím:	Diagnostic approach and therapeutic management in early-stage endometrial cancer / A. Koukoulomati, P. Tsikouras, N. Tsagias, R. Csorba, A. Liberis, A. T. Teichmann, V. S. Liberis, G. Galazios
Dátum:	2013
ISSN:	0392-2936
Megjegyzések:	OBJECTIVE:The effectiveness of pelvic and para-aortic lymphadenectomy in the morbidity of patients affected by early-stage endometrial carcinoma (EC) is the subject of this study.STUDY DESIGN:Ninety-two cases with endometrial cancer that underwent para-aortic and pelvic lymphadenectomy, from June 1995 to June 2006, were studied and compared with 30 cases of patients with endometrial cancer without lymphadenectomy.RESULTS:According to the results, systematic pelvic and para-aortic lymphadenectomies improved disease-free and overall survival rates among the patients with endometrial cancer. The mean number of removed para-aortic lymph nodes was 19.01 +/- 5.88, whereas the mean number of removed iliac lymph nodes was 32.94 +/- 6.69. Forty-two and 31 metastatic iliac and para-aortic nodes were found, respectively. No surgery-related deaths and major intraoperative injuries occurred. The frequency and the type of postoperative complications were not affected by the performance of lymphadenectomy. The morbidity rate was 6.2%, similar to the group without lymphadenectomy (5.79%). No recurrence occurred in the group with lymphadenectomy, while in the other group the recurrence rate was 23.3%.CONCLUSIONS:Lymph nodes metastases can be observed in early stages of EC. Pelvic and para-aortic lymphadenectomies seems to provide profound information about the Stage of the disease and the patient's survival, identifying which patients are suitable for supplementary treatment, without significant clinical increase of morbidity.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Endometrial cancer Paraortal iliac lymphadenectomy morbidity early stages
Megjelenés:	European Journal of Gynaecological Oncology. - 34 : 4 (2013), p. 319-321. -
További szerzők:	Tsikouras, Panagioti Tsagias, Nikolaos Csorba Roland (1972-) (szülész-nőgyógyász, gyermeknőgyógyász) Liberis, Anastasios Teichmann, Alexander Liberis, V. S. Galazios, Georgios
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM048821
Első szerző:	Tsikouras, Panagioti
Cím:	The contribution of catumaxomab in the treatment of malignant ascites in patients with ovarian cancer : a review of the literature / Panagiotis Tsikouras, Nikolaos Tsagias, Petros Pinidis, Roland Csorba, Nikolaos Vrachnis, Alexandros Dafopoulos, Sophia Bouchlariotou, Anastasios Liberis, Alexander Tobias Teichmann, Georg Friedrich von Tempelhoff
Dátum:	2013
ISSN:	0932-0067 1432-0711
Megjegyzések:	The approval of the first specific drug catumaxomab for the treatment of malignant ascites is the subject of this review. This trifunctional antibody is known to kill EpCAM-positive tumor cells and therefore attacks the primary cause of malignant ascites formation in the peritoneal cavity. Until today catumaxomab is the only EpCam-targeted antibody approved by the European Medicines Agency. Ovarian cancer is caused by epithelial tumors cells which overexpress epithelial cell adhesion molecule (EpCAM). The existing literature concerning the use of catumaxomab for the treatment of malignant ascites associated with ovarian cancer until today is reported in this article. It is very encouraging that different prospective studies from diverse scientific teams recently presented positive results concerning the efficacy and the safety of catumaxomab in the treatment of malignant ascites in patients with ovarian cancer. A case of a patient with ovarian cancer FIGO IIIc is also referred in this article. A complete remission and stable disease was found after 4 i.p. infusions of catumaxomab.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Catumaxomab Malignant ascites Ovarian cancer
Megjelenés:	Archives of Gynecology and Obstetrics. - 288 : 3 (2013), p. 581-585. -
További szerzők:	Tsagias, Nikolaos Pinidis, Petros Csorba Roland (1972-) (szülész-nőgyógyász, gyermeknőgyógyász) Vrachnis, Nikolaos Dafopoulos, Alexandros Bouchlariotou, Sofia Liberis, Anastasios Teichmann, Alexander Tempelhoff, Georg-Friedrich von
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