Találati lista | Tudóstér

001-es BibID:	BIBFORM023099
Első szerző:	Huszár Gábor
Cím:	Hyaluronic acid binding by human sperm : andrology evaluation of male fertility and sperm selection for intracytoplasmic sperm injection / Gabor Huszar, Attila Jakab, Ciler Celik-Ozenci, Leyla G. Sati
Dátum:	2006
Tárgyszavak:	Orvostudományok Klinikai orvostudományok könyvfejezet andrology sperm function sperm selection
Megjelenés:	Male Infertility - Diagnosis and Treatment / eds. Kruger T. F., Oehninger S. C.. - p. 413-425
További szerzők:	Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Celik-Ozenci, Ciler Sati, Leyla G.
Borító:
Saját polcon:

001-es BibID:	BIBFORM023079
Első szerző:	Huszár Gábor
Cím:	Hyaluronic acid binding ability of human sperm reflects cellular maturity and fertilizing potential : selection of sperm for intracytoplasmic sperm injection / Huszár G., Ozkavukcu S., Jakab A., Celik-Ozenci C., Sati L. G., Cayli S.
Dátum:	2006
ISSN:	1040-872X
Megjegyzések:	The current concepts of sperm biochemical markers and the central role of the HspA2 chaperone protein, a measure of sperm cellular maturity and fertilizing potential, are reviewed. RECENT FINDINGS: Because HspA2 is a component of the synaptonemal complex, low HspA2 levels and increased frequency of chromosomal aneuploidies are related in diminished maturity sperm. We also suggest a relationship between HspA2 expression in elongating spermatids and events of late spermiogenesis, such as cytoplasmic extrusion and plasma membrane remodeling that aid the formation of the zona pellucida binding and hyaluronic acid binding sites. The presence of hyaluronic acid receptor on the plasma membrane of mature sperm, coupled with hyaluronic acid coated glass or plastic surfaces, facilitates testing of sperm function and selection of single mature sperm for intracytoplasmic sperm injection. The frequencies of sperm with chromosomal disomy are reduced approximately fourfold to fivefold in hyaluronic acid selected sperm compared with semen sperm, comparable to the increase in such abnormalities in intracytoplasmic sperm injection offspring. Hyaluronic acid binding also excludes immature sperm with cytoplasmic extrusion, persistent histones, and DNA chain breaks. SUMMARY: Hyaluronic acid mediated sperm selection is a novel technique that is comparable to sperm zona pellucida binding. Hyaluronic acid selected sperm will also alleviate the risks related to intracytoplasmic sperm injection fertilization with sperm of diminished maturity that currently cause worldwide concern.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban chromosomal disomy and diploidy intracytoplasmic sperm injection sperm maturation zona pellucida binding
Megjelenés:	Current Opinion In Obstetrics & Gynecology. - 18 : 3 (2006), p. 260-267. -
További szerzők:	Ozkavukcu, Sinan Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Celik-Ozenci, Ciler Sati, Leyla G. Cayli, Sevil
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
Borító:
Saját polcon:

001-es BibID:	BIBFORM023078
Első szerző:	Zavaczki Zoltán
Cím:	Dimensional assessment of X-bearing and Y-bearing haploid and disomic human sperm with the use of fluorescence in situ hybridization and objective morphometry / Zavaczki Z., Celik-Ozenci C., Ovari L., Jakab A., Sati G. L., Ward D. C., Huszar G.
Dátum:	2006
ISSN:	0015-0282
Megjegyzések:	To explore the dimensional attributes of haploid and disomic X-bearing and Y-bearing spermatozoa. Design: Morphometric evaluation of more than 2,000 X-bearing and Y-bearing spermatozoa after identification of the genotype with fluorescence in situ hybridization. Setting: Academic clinical and research andrology laboratory. Main Outcome Measure(s): Sperm head area, perimeter, long axis, short axis, shape factor, elliptical form factor (long axis/short axis), and tail length. Result(s): We found no differences in dimensions or dimensional distributions between X-bearing and Y-bearing spermatozoa, whether in the native or the decondensed state, or in oligozoospermic or normozoospermic men. There were inconsistent differences and a 70% overlap in the dimensions of haploid and disomic spermatozoa. The other 30% of sperm with disomic nuclei were either smaller or larger compared to haploid spermatozoa. Conclusion(s): There are no differences, or distinguishing characteristics, in dimensions or dimensional distri- butions between X-bearing and Y-bearing spermatozoa. Dimensional attributes do not discriminate between dysomic and haploid spermatozoa.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Sperm X-bearing spermatozoa dimensional attributes haploid dosomic
Megjelenés:	Fertility And Sterility. - 85 : 1 (2006), p. 121-127. -
További szerzők:	Celik-Ozenci, Ciler Óvári László (szülész-nőgyógyász, sebész) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Sati, Leyla G. Ward, David Huszár Gábor
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: