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001-es BibID:BIBFORM090220
035-os BibID:(Scopus)85098501592 (WOS)000604059600029
Első szerző:Bosch, Thierry van den
Cím:Typical ultrasound features of various endometrial pathologies described using International Endometrial Tumor Analysis (IETA) terminology in women with abnormal uterine bleeding / Van Den Bosch T., Verbakel J. Y., Valentin L., Wynants L., De Cock B., Pascual M. A., Leone F. P. G., Sladkevicius P., Alcazar J. L., Votino A., Fruscio R., Lanzani C., Van Holsbeke C., Rossi A., Jokubkiene L., Kudla M., Jakab A., Domali E., Epstein E., Van Pachterbeke C., Bourne T., Van Calster B., Timmerman D.
Dátum:2021
ISSN:0960-7692 1469-0705
Megjegyzések:Objective To describe the ultrasound features of differ- ent endometrial and other intracavitary pathologies in pre- and postmenopausal women presenting with abnor- mal uterine bleeding, using the International Endometrial Tumor Analysis (IETA) terminology. Methods This was a prospective observational multi- center study of consecutive women presenting with abnormal uterine bleeding. Unenhanced sonography with color Doppler and fluid-instillation sonography were performed. Endometrial sampling was performed according to each center's local protocol. The his- tological endpoints were cancer, atypical endome- trial hyperplasia/endometrioid intraepithelial neoplasia (EIN), endometrial atrophy, proliferative or secretory endometrium, endometrial hyperplasia without atypia, endometrial polyp, intracavitary leiomyoma and other. For fluid-instillation sonography, the histological end- points were endometrial polyp, intracavitary leiomyoma and cancer. For each histological endpoint, we report typical ultrasound features using the IETA terminology. Results The database consisted of 2856 consecutive women presenting with abnormal uterine bleeding.Unenhanced sonography with color Doppler was per- formed in all cases and fluid-instillation sonography in 1857. In 2216 women, endometrial histology was avail- able, and these comprised the study population. Median age was 49 years (range, 19 ? 92 years), median parity was 2 (range, 0 ? 10) and median body mass index was 24.9 kg/m2 (range, 16.0 ? 72.1 kg/m2 ). Of the study population, 843 (38.0%) women were postmenopausal. Endometrial polyps were diagnosed in 751 (33.9%) women, intracavitary leiomyomas in 223 (10.1%) and endometrial cancer in 137 (6.2%). None (0% (95% CI, 0.0?5.5%)) of the 66 women with endometrial thickness <3mm had endometrial cancer or atypical hyperpla- sia/EIN. Endometrial cancer or atypical hyperplasia/EIN was found in three of 283 (1.1% (95% CI, 0.4 ? 3.1%)) endometria with a three-layer pattern, in three of 459 (0.7% (95% CI, 0.2 ? 1.9%)) endometria with a linear endometrial midline and in five of 337 (1.5% (95% CI, 0.6 ? 3.4%)) cases with a single vessel without branching on unenhanced ultrasound. Conclusions The typical ultrasound features of endome- trial cancer, polyps, hyperplasia and atrophy and intracavitary leiomyomas, are described using the IETA terminology. The detection of some easy-to-assess IETA features (i.e. endometrial thickness <3mm, three-layer pattern, linear midline and single vessel without branching) makes endometrial cancer unlikely. Copyright ? 2020 ISUOG. Published by John Wiley & Sons Ltd.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
cancer
diagnosis
endometrium
hyperplasia
IETA
leiomyoma
polyp
sonohysterographia
ultrasonography
Megjelenés:Ultrasound In Obstetrics & Gynecology. - 57 : 1 (2021), p. 164-172. -
További szerzők:Verbakel, J. Y. Valentin, Lil Wynants, L. De Cock, B. Pascual, M. Angela Leone, F. P. G. Sladkevicius, P. Alcazar, Juan Luis Votino, A. Fruscio, Robert Lanzani, C. Van Holsbeke, C. Rossi, A. Jokubkiene, L. Kudla, M. Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Domali, E. Epstein, Elisabeth Van Pachterbeke, C. Bourne, T. Van Calster, B. Timmerman, D.
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2.

001-es BibID:BIBFORM071864
Első szerző:Green, R. W.
Cím:Inter- and intrarater reproducibility in detecting deep myometrial invasion and cervical stromal invasion using 2D-TVU and 3D-VCI / Green R. W., Valentin L., Alcazar J., Van den Bosch T., Chiappa V., Erdodi B., Franchi D., Fruhauf P., Fruscio R., Guerriero S., Graupera B., Jakab A., Di Legge A., Ludovisi M., Mascilini F., Pascual M., Epstein E.
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
ultrasound
3D
gynecology
endometrial cancer
Megjelenés:International Society of Ultrasound in Obstetrics and Gynecology 50 : Suppl. 1. (2017), p. 197. -
További szerzők:Valentin, Lil Alcazar, Juan Luis Bosch, Thierry van den Chiappa, Valentina Erdődi Balázs (1984-) (szülész-nőgyógyász szakorvosjelölt) Franchi, Dorella Fruhauf, P. Fruscio, Robert Guerriero, Stefano Graupera, B. Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Di Legge, Alessia Ludovisi, Manuela Mascilini, Floriana Pascual, M. Angela Epstein, Elisabeth
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3.

001-es BibID:BIBFORM071863
Első szerző:Green, R. W.
Cím:2D-TVU is more accurate modality than 3D-VCI in staging endometrial cancer / Green R. W., Valentin L., Alcazar J., Van den Bosch T., Chiappa V., Erdodi B., Franchi D., Fruhauf P., Fruscio R., Guerriero S., Graupera B., Jakab A., Di Legge A., Ludovisi M., Mascilini F., Pascual M., Epstein E.
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
ultrasound
3D
gynecology
endometrial cancer
Megjelenés:International Society of Ultrasound in Obstetrics and Gynecology 50 : Suppl. 1. (2017), p. 36. -
További szerzők:Valentin, Lil Alcazar, Juan Luis Bosch, Thierry van den Chiappa, Valentina Erdődi Balázs (1984-) (szülész-nőgyógyász szakorvosjelölt) Franchi, Dorella Fruhauf, P. Fruscio, Robert Guerriero, Stefano Graupera, B. Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Di Legge, Alessia Ludovisi, Manuela Mascilini, Floriana Pascual, M. Angela Epstein, Elisabeth
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4.

001-es BibID:BIBFORM077450
035-os BibID:(WoS)000444528400008 (Scopus)85049904747
Első szerző:Green, Rasmus W.
Cím:Endometrial cancer off-line staging using two-dimensional transvaginal ultrasound and three-dimensional volume contrast imaging : intermethod agreement, interrater reliability and diagnostic accuracy / Rasmus W. Green, Lil Valentin, Juan Luis Alcazar, Valentina Chiappa, Balazs Erdodi, Dorella Franchi, Filip Frühauf, Robert Fruscio, Stefano Guerriero, Betlem Graupera, Attila Jakab, Alessia di Legge, Manuela Ludovisi, Floriana Mascilini, M. Angela Pascual, Thierry van den Bosch, Elisabeth Epstein
Dátum:2018
ISSN:0090-8258
Megjegyzések:Objectives. The aim is to estimate agreement between two-dimensional transvaginal ultrasound (2D-TVS) and three-dimensional volume contrast imaging (3D-VCI) in diagnosing deep myometrial invasion (MI) and cer- vical stromal involvement (CSI) of endometrial cancer and to compare the two methods regarding inter-rater re- liability and diagnostic accuracy. Methods. Fifteen ultrasound experts assessed off-line de-identified 3D-VCI volumes and 2D-TVU video clips from 58 patients with biopsy-confirmed endometrial cancer regarding the presence of deep (?50%) MI and CSI. Video clips and 3D volumes were assessed independently. Interrater reliability was measured using kappa statistics. Histological diagnosis after hysterectomy served as gold standard. Accuracy measurements were corre- lated to rater experience using Spearman's rank correlation coefficient (?). Results. Agreement between 2D-TVU and 3D-VCI for diagnosing MI was median 76% (range 64?93%) and for CSI median 88% (range 79?97%). Interrater reliability was better for 2D-TVU than for 3D-VCI (Fleiss' kappa 0.41 vs. 0.31 for MI and 0.55 vs. 0.45 for CSI). Median accuracy for diagnosing deep MI was 76% (range 59?84%) with 2D-TVU and 69% (range 52?83%) for 3D-VCI; the corresponding figures for CSI were 88% (range 81?93%) and 86% (range 72?95%). Accuracy was significantly correlated to how many cases the raters assessed annually. Conclusions. Off-line assessment of MI and CSI in women with endometrial cancer using 3D-VCI has lower interrater reliability and lower accuracy than 2D-TVU video clip assessment. Since accuracy was cor- related to the number of cases assessed annually it is advised to centralize these examinations to high-vol- ume centres.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
endometrial cancer
ultrasound
diagnostic accuracy
Megjelenés:Gynecologic Oncology. - 150 : 3 (2018), p. 438-445. -
További szerzők:Valentin, Lil Alcazar, Juan Luis Chiappa, Valentina Erdődi Balázs (1984-) (szülész-nőgyógyász szakorvosjelölt) Franchi, Dorella Frühauf, Filip Fruscio, Robert Guerriero, Stefano Graupera, Betlem Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Di Legge, Alessia Ludovisi, Manuela Mascilini, Floriana Pascual, M. Angela Bosch, Thierry van den Epstein, Elisabeth
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5.

001-es BibID:BIBFORM090218
Első szerző:ESHRE working group on Ectopic Pregnancy
Cím:Terminology for describing normally sited and ectopic pregnancies on ultrasound : ESHRE recommendations for good practice / The ESHRE working group on Ectopic Pregnancy, Emma Kirk, Pim Ankum, Attila Jakab, Nathalie Le Clef, Artur Ludwin, Rachel Small, Tina Tellum, Mira Töyli, Thierry Van den Bosch, Davor Jurkovic
Dátum:2020
ISSN:2399-3529
Megjegyzések:STUDY QUESTION: What recommendations can be provided to improve terminology for normal and ectopic pregnancy description on ultrasound? SUMMARY ANSWER: The present ESHRE document provides 17 consensus recommendations on how to describe normally sited and different types of ectopic pregnancies on ultrasound. WHAT IS KNOWN ALREADY: Current diagnostic criteria stipulate that each type of ectopic pregnancy can be defined by clear anatomical landmarks which facilitates reaching a correct diagnosis. However, a clear definition of normally sited pregnancies and a comprehensive classification of ectopic pregnancies are still lacking. STUDY DESIGN, SIZE, DURATION: A working group of members of the ESHRE Special Interest Group in Implantation and Early Pregnancy (SIG-IEP) and selected experts in ultrasound was formed in order to write recommendations on the classification of ectopic pregnancies. PARTICIPANTS/MATERIALS, SETTING, METHODS: The working group included nine members of different nationalities with internationally recognised experience in ultrasound and diagnosis of ectopic pregnancies on ultrasound. This document is developed according to the manual for development of ESHRE recommendations for good practice. The recommendations were discussed until consensus by the working group, supported by a survey among the members of the ESHRE SIG-IEP. MAIN RESULTS AND THE ROLE OF CHANCE: A clear definition of normally sited pregnancy on ultrasound scan is important to avoid misdiagnosis of uterine ectopic pregnancies. A comprehensive classification of ectopic pregnancy must include definitions and descriptions of each type of ectopic pregnancy. Only a classification which provides descriptions and diagnostic criteria for all possible locations of ectopic pregnancy would be fit for use in routine clinical practice. The working group formulated 17 recommendations on the diagnosis of the different types of ectopic pregnancies on ultrasound. In addition, for each of the types of ectopic pregnancy, a schematic representation and examples on 2D and 3D ultrasound are provided. LIMITATIONS, REASONS FOR CAUTION: Owing to the limited evidence available, recommendations are mostly based on clinical and technical expertise. ESHRE Pages content is not externally peer reviewed. The manuscript has been approved by the Executive Committee of ESHRE. VC The Author(s) 2020. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com Downloaded from https://academic.oup.com/hropen/article/2020/4/hoaa055/6038915 by eresources@lib.unideb.hu user on 06 January 2021 2 Kirk et al. WIDER IMPLICATIONS OF THE FINDINGS: This document is expected to have a significant impact on clinical practice in ultrasound for early pregnancy. The development of this terminology will help to reduce the risk of misdiagnosis and inappropriate treatment. STUDY FUNDING/COMPETING INTEREST(S): The meetings of the working group were funded by ESHRE. T.T. declares speakers' fees from GE Healthcare. The other authors declare that they have no conflict of interest. TRIAL REGISTRATION NUMBER: N/A DISCLAIMER: This Good Practice Recommendations (GPR) document represents the views of ESHRE, which are the result of consensus between the relevant ESHRE stakeholders and where relevant based on the scientific evidence available at the time of preparation. ESHRE's GPRs should be used for informational and educational purposes. They should not be interpreted as setting a standard of care or be deemed inclusive of all proper methods of care nor exclusive of other methods of care reasonably directed to obtaining the same results. They do not replace the need for application of clinical judgement to each individual presentation, nor variations based on locality and facility type. Furthermore, ESHRE's GPRs do not constitute or imply the endorsement, recommendation or favouring of any of the in- cluded technologies by ESHRE.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
ectopic pregnancy
terminology
ultrasound
early pregnancy
ESHRE
guideline
Megjelenés:Human Reproduction Open. - 2020 : 4 (2020), p. 1-21. -
További szerzők:Kirk, Emma Ankum, Pim Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Le Clef, Nathalie Ludwin, Artur Small, Rachel Tellum, Tina Töyli, Mira Bosch, Thierry van den Jurkovic, Davor
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