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001-es BibID:	BIBFORM015677
Első szerző:	Sun, Xiao
Cím:	The role of actin and myosin during spermatogenesis / Sun Xiao, Kovacs Tamas, Hu Yan-Jun, Yang Wan-Xi
Dátum:	2010
ISSN:	0301-4851
Megjegyzések:	Spermatogenesis is a transitionary process in which the diploid spermatogonia transform into haploid mature spermatozoa. Actin and myosin have been implicated in various aspects during spermatogenesis. Actin is present in the form of monomer, oligomer and polymer within cells, the latter is called microfilament. There are five actin-containing structures during spermatogenesis, i.e., ectoplasmic specialization, acroplaxome, manchette in mammals, actin cones in Drosophila and acroframosome in Caridean shrimp. They are involved in the shaping and differentiating of spermatids. Along with spermatogenesis, the actin cytoskeletons show active remodeling in this process. Some actin binding or actin regulated proteins have been demonstrated to regulate dynamic changes of the actin-containing structures. Myosin, actin-dependent molecular motor, plays an important role during spermatogenesis, such as involving in acrosome biogenesis, vesicle transport, gene transcription and nuclear shaping. The actin cytoskeleton and actin binding/regulated proteins cooperate to facilitate spermatogenesis. In this review, we summarize the existing knowledge about the cytoskeletal structures consisting of actin, actin binding/regulated proteins and myosin during spermatogenesis.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban actin myosin spermatogenesis acrosome biogenesis nuclear shaping
Megjelenés:	Molecular Biology Reports. - 38 : 6 (2010), p. 3993-4001. -
További szerzők:	Kovács Tamás (1959-) (szülész-nőgyógyász, humángenetikus) Hu, Yan-Jun Yang, Wan-Xi
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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