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1.

001-es BibID:BIBFORM067628
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Vitamin D : musculoskeletal health / Harjit Pal Bhattoa, Jerzy Konstantynowicz, Natalia Laszcz, Marek Wojcik, Pawel Pludowski
Dátum:2017
Megjegyzések:Perhaps the role of Vitamin D supplementation has been most exhaustively studied in calcium absorption, skeletal wellbeing, muscular potency, balance and risk of falling. Nonetheless, new data has emerged and the recent research on sarcopenia makes the topic increasingly interesting. Given the socioeconomic burden of the musculoskeletal consequences of hypovitaminosis D it is vital to keep abreast with the latest literature in the field. The recommended Vitamin D supplementation dose should suffice to increase the serum 25 hydroxyvitamin D level to 30 ng/mL (75 nmol/L) and this level should be optimally maintained with a maintenance dose, particularly for those diagnosed with osteoporosis.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Vitamin D
Bone
Muscle
Osteoporosis
Falls
Sarcopenia
Megjelenés:Reviews in Endocrine and Metabolic Disorders 18 : 3 (2017), p. 363-371. -
További szerzők:Konstantynowicz, Jerzy Laszcz, Natalia Wojcik, Marek Pludowski, Pawel
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2.

001-es BibID:BIBFORM116025
035-os BibID:(Scopus)85179259710
Első szerző:Grant, William B.
Cím:Determinants of vitamin D levels from sun exposure : a global perspective / William B. Grant, Harjit P. Bhattoa, Pawel Pludowski
Dátum:2024
Megjegyzések:Vitamin D deficiency, generally defined as 25-hydroxyvitamin D (25(OH)D) concentration <50 nmol/L, affects nearly half the world's population. However, optimal 25(OH)D concentration is much higher, depending on the particular outcome. Solar ultraviolet B (UVB) exposure is the primary source of vitamin D for most people. Wintertime 25(OH)D concentrations are maintained at 60%-80% of summertime concentrations through a combination of recirculating 25(OH)D stored in muscle cells, oral intake, and at lower latitudes, some UVB exposure. Many factors affect 25(OH)D concentrations related to solar UVB exposure, including skin pigmentation, solar zenith angle, atmospheric aerosols and clouds, time spent in the sun, amount of skin surface area exposed, use of sunscreen, age, and body mass index. Cultural and lifestyle differences - such as beauty standards, including high regard for fair skin in darker-skinned populations and avoidance of wrinkling, occupation, religion-related clothing, urban/rural residence, and fear of developing skin cancer or melanoma - also affect some of those factors. Thus, fortification of food with vitamin D and vitamin D supplementation would have to be employed to compensate for unavoidable or inconvenient lack of solar UVB exposure.
ISBN:978-0-323-91338-6
Tárgyszavak:Orvostudományok Klinikai orvostudományok könyvfejezet
könyvrészlet
Megjelenés:Feldman and Piké's Vitamin D, fifth Edition / eds. Hewison M., Bouillon R., Giovannucci E., Goltzman D., Meyer M., Welsh J.. - p. 97-113. -
További szerzők:Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Pludowski, Pawel
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3.

001-es BibID:BIBFORM091926
Első szerző:Grant, William B.
Cím:Nursing home residents could reduce risk of COVID-19 by supplementing with vitamin D3 - Rapid Response to : Covid-19: Continued outbreaks in care homes risk extending pandemic, say experts / William B. Grant, Carole A. Baggerly, Harjit P. Bhattoa, Barbara J. Boucher, Meis Moukayed, Pawel Pludowski
Dátum:2020
ISSN:1756-1833
Tárgyszavak:Orvostudományok Klinikai orvostudományok hozzászólás
folyóiratcikk
Megjelenés:BMJ. - 369 (2020), p. m2530. -
További szerzők:Baggerly, Carole A. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Boucher, Barbara Moukayed, Meis Pludowski, Pawel
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4.

001-es BibID:BIBFORM073727
Első szerző:Grant, William B.
Cím:Determinants of Vitamin D Deficiency From Sun Exposure : a Global Perspective / Grant William B., Bhattoa Harjit Pal, Pludowski Pawel
Dátum:2018
Megjegyzések:Vitamin D deficiency, generally defined as 25-hydroxyvitamin D (25(OH)D) concentration <50 nmol/L, affects nearly half the world's population. Solar ultraviolet B (UVB) exposure is the primary source of vitamin D for most people. Many factors affect 25(OH)D concentrations related to solar UVB exposure, including skin pigmentation, solar zenith angle, atmospheric aerosols and clouds, time spent in the sun, amount of skin surface area exposed, use of sunscreen, age, and body mass index. Cultural and lifestyle differences?such as beauty standards, including high regard for fair skin in darker-skinned populations and avoidance of wrinkling; occupation; religion; urban/rural residence; and fear of developing skin cancer or melanoma?also affect some of those factors. Thus, fortification of food with vitamin D and vitamin D supplementation would have to be employed to compensate for unavoidable or inconvenient lack of solar UVB exposure.
ISBN:978-0-12-809963-6
Tárgyszavak:Orvostudományok Klinikai orvostudományok könyvfejezet
25-Hydroxyvitamin D
Shadow rule
Skin cancer
Solar
Sunscreen
Ultraviolet B
Vitamin D
Megjelenés:Vitamin D (4th edition) / Ed. Feldman David, Pike J. Wesley, Bouillon Roger, Giovannucci Edward, Goltzman David, Hewison Martin. - p. 79-90. -
További szerzők:Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Pludowski, Pawel
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5.

001-es BibID:BIBFORM067627
Első szerző:Pludowski, Pawel
Cím:Vitamin D supplementation guidelines / Pawel Pludowski, Michael F. Holick, William B. Grant, Jerzy Konstantynowicz, Mario R. Mascarenhas, Afrozul Haq, Vladyslav Povoroznyuk, Nataliya Balatska, Ana Paula Barbosa, Tatiana Karonova, Ema Rudenka, Waldemar Misiorowski, Irina Zakharova, Alena Rudenka, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Natalia Laszcz, Pawel Abramowicz, Harjit P. Bhattoa, Sunil J. Wimalawansa
Dátum:2018
Megjegyzések:Research carried out during the past two-decades extended the understanding of actions of vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many pleiotropic actions in organs and tissues in the body. Most observational and ecological studies report association of higher serum 25-hydroxyvitamin D [25(OH)D] concentrations with improved outcomes for several chronic, communicable and non-communicable diseases. Consequently, numerous agencies and scientific organizations have developed recommendations for vitamin D supplementation and guidance on optimal serum 25(OH)D concentrations. The bone-centric guidelines recommend a target 25(OH)D concentration of 20 ng/mL (50 nmol/L), and age-dependent daily vitamin D doses of 400?800 IU. The guidelines focused on pleiotropic effects of vitamin D recommend a target 25(OH)D concentration of 30 ng/mL (75 nmol/L), and age-, body weight-, disease-status, and ethnicity dependent vitamin D doses ranging between 400 and 2000 IU/day. The wise and balanced choice of the recommendations to follow depends on one's individual health outcome concerns, age, body weight, latitude of residence, dietary and cultural habits, making the regional or nationwide guidelines more applicable in clinical practice. While natural sources of vitamin D can raise 25(OH)D concentrations, relative to dietary preferences and latitude of residence, in the context of general population, these sources are regarded ineffective to maintain the year-round 25(OH)D concentrations in the range of 30?50 ng/mL (75?125 nmol/L). Vitamin D self-administration related adverse effects, such as hypercalcemia and hypercalciuria are rare, and usually result from taking extremely high doses of vitamin D for a prolonged time.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Vitamin D
25(OH)D
Pleiotropic
Extra-skeletal effects
Global
Recommendations
Megjelenés:The Journal of Steroid Biochemistry and Molecular Biology 175 (2018), p. 125-135. -
További szerzők:Holick, Michael F. Grant, William B. Konstantynowicz, Jerzy Mascarenhas, Mario R. Haq, Afrozul Povoroznyuk, Vladyslav Balatska, Nataliya Barbosa, Ana Paula Karonova, Tatiana Rudenka, Ema Misiorowski, Waldemar Zakharova, Irina Rudenka, Alena Łukaszkiewicz, Jacek Marcinowska-Suchowierska, Ewa Laszcz, Natalia Abramowicz, Pawel Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Wimalawansa, Sunil J.
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6.

001-es BibID:BIBFORM054103
035-os BibID:Article ID: 589587
Első szerző:Pludowski, Pawel
Cím:Vitamin D Status in Central Europe / Pawel Pludowski, William B. Grant, Harjit Pal Bhattoa, Milan Bayer, Vladyslav Povoroznyuk, Ema Rudenka, Heorhi Ramanau, Szabolcs Varbiro, Alena Rudenka, Elzbieta Karczmarewicz, Roman Lorenc, Justyna Czech-Kowalska, Jerzy Konstantynowicz
Dátum:2014
ISSN:1687-8337 1687-8345
Megjegyzések:Little published information is available regarding epidemiological data on vitamin D status in the large geographical region ofCentral Europe (CE). We searched the journal literature with regard to 25(OH)D concentrations among community-dwelling orhealthy people living in CE. 25(OH)D concentrations varied by age, season, study sample size, andmethodological approach [i.e.,25(OH)D assay used]. Concentrations of 25(OH)D in CE appeared lower than 30 ng/mL, and the magnitude of hypovitaminosisD was similar to that reported inWestern Europe.While most of the studies reviewed were cross-sectional studies, a longitudinalstudy was also included to obtain information on seasonal variability. The longitudinal study reported wintertime 25(OH)D valuesclose to 21?23 ng/mL for all studied age groups, with a significant increase of 25(OH)D in August reaching 42 ng/mL for thoseaged 0?9 years, but only 21 ng/mL for the elderly aged 80?89 years.The decrease in 25(OH)D with respect to age was attributed todecreased time spent in the sun and decreased vitamin D production efficiency. Based on the literature review on vitamin D statusin the CE populations, it can be concluded that 25(OH)vitamin D levels are on average below the 30 ng/mL level.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
vitamin d, 25(OH)D,
Megjelenés:International Journal of Endocrinology. - 2014 (2014), [13] p. -
További szerzők:Grant, William B. Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Bayer, Milan Povoroznyuk, Vladyslav Rudenka, Ema Ramanau, Heorhi Várbíró Szabolcs Rudenka, Alena Karczmarewicz, Elzbieta Lorenc, Roman Czech-Kowalska, Justyna Konstantynowicz, Jerzy
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