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001-es BibID:	BIBFORM082799
035-os BibID:	(PMID)31907366
Első szerző:	Altieri, Barbara
Cím:	Vitamin D testing : advantages and limits of the current assays / Barbara Altieri, Etienne Cavalier, Harjit Pal Bhattoa, Faustino R. Pérez-López, María T. López-Baena, Gonzalo R. Pérez-Roncero, Peter Chedraui, Cedric Annweiler, Silvia Della Casa, Sieglinde Zelzer, Markus Herrmann, Antongiulio Faggiano, Annamaria Colao, Michael F. Holick
Dátum:	2020
ISSN:	0954-3007
Megjegyzések:	Vitamin D deficiency and insufficiency has become a pandemic health problem with a consequent increase of requests for determining circulating levels of 25-hydroxyvitamin D [25(OH)D]. However, the analytical performance of these immunoassays, including radioimmunoassay and ELISA, is highly variable, and even mass spectrometric methods, which nowadays serves as the gold standard for the quantitatively determination of 25(OH)D, do not necessarily produce comparable results, creating limitations for the definition of normal vitamin D status ranges. To solve this problem, great efforts have been made to promote standardization of laboratory assays, which is important to achieve comparable results across different methods and manufacturers. In this review, we performed a systematic analysis evaluating critically the advantages and limits of the current assays available for the measure of vitamin D status, i.e., circulating 25(OH)D and its metabolites, making suggestions that could be used in the clinical practice. Moreover, we also suggest the use of alternatives to blood test, including standardized surveys that may be of value in alerting health-care professionals about the vitamin D status of their patients.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	European Journal Of Clinical Nutrition. - 74 : 2 (2020), p. 231-247. -
További szerzők:	Cavalier, Etienne Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Pérez-López, Faustino R. López-Baena, María T. Pérez-Roncero, Gonzalo R. Chedraui, Peter Annweiler, Cedric Della Casa, Silvia Zelzer, Sieglinde Herrmann, Markus Faggiano, Antongiulio Colao, Annamaria Holick, Michael F.
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001-es BibID:	BIBFORM081578
035-os BibID:	(PMID)30963976
Első szerző:	Muscogiuri, Giovanna
Cím:	Calcium and Vitamin D Supplementation : myths and Realities with Regard to Cardiovascular Risk / Giovanna Muscogiuri, Luigi Barrea, Barbara Altieri, Carolina Di Somma, Harjit Pal Bhattoa, Daniela Laudisio, Guillaume T. Duval, Gabriella Pugliese, Cédric Annweiler, Francesco Orio, Hana Fakhouri, Silvia Savastano, Annamaria Colao
Dátum:	2019
ISSN:	1570-1611
Megjegyzések:	Vitamin D and calcium are considered crucial for the treatment of bone diseases. Both vitamin D and calcium contribute to bone homeostasis but also preserve muscle health by reducing the risk of falls and fractures. Low vitamin D concentrations result in secondary hyperparathyroidism and contribute to bone loss, although the development of secondary hyperparathyroidism varies, even in patients with severe vitamin D deficiency. Findings from observational studies have shown controversial results regarding the association between bone mineral density and vitamin D/calcium status, thus sparking a debate regarding optimum concentrations of 25-hydroxyvitamin D and calcium for the best possible skeletal health. Although most of the intervention studies reported a positive effect of supplementation with calcium and vitamin D on bone in patients with osteoporosis, this therapeutic approach has been a matter of debate regarding potential side effects on the cardiovascular (CV) system. Thus, the aim of this review is to consider the current evidence on the physiological role of vitamin D and calcium on bone and muscle health. Moreover, we provide an overview on observational and interventional studies that investigate the effect of vitamin D and calcium supplementation on bone health, also taking into account the possible CV side-effects. We also provide molecular insights on the effect of calcium plus vitamin D on the CV system.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Vitamin D bone health calcium cardiovascular system myocardial infarction stroke
Megjelenés:	Current Vascular Pharmacology. - 17 : 6 (2019), p. 610-617. -
További szerzők:	Barrea, Luigi Altieri, Barbara Di Somma, Carolina Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Laudisio, Daniela Duval, Guillaume Pugliese, Gabriella Annweiler, Cedric Orio, Francesco Fakhoury, Hana M. A. Savastano, Silvia Colao, Annamaria
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001-es BibID:	BIBFORM067623
Első szerző:	Muscogiuri, Giovanna
Cím:	Vitamin D and cardiovascular disease : from atherosclerosis to myocardial infarction and stroke / Giovanna Muscogiuri, Cedric Annweiler, Guillaume Duval, Spyridon Karras, Giacomo Tirabassi, Gianmaria Salvio, Giancarlo Balercia, Samantha Kimball, Kalliopi Kotsa, Luca Mascitelli, Harjit Pal Bhattoa, Annamaria Colao
Dátum:	2017
ISSN:	0167-5273
Megjegyzések:	There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). In fact vitamin D deficiency has been associated to an increased risk of developing CVD given to the relationship between low vitamin D levels and obesity, diabetes mellitus, dyslipidaemia, endothelial dysfunction and hypertension. However, although vitamin D has been identified as a potentially important marker of CVD, the mechanisms through which vitamin D deficiency leads from endothelial dysfunction to myocardial infarction and stroke are not fully understood. Thus, the goal of this review is to provide an updated review of the literature on the basic science of how vitamin D may affect the cardiovascular system and in particular to analyze the role that vitamin D may have in the whole dynamic process from the initiation of endothelial dysfunction to the development of myocardial infarction and stroke.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Atherosclerosis Environment Lifestyle Myocardial infarction Stroke Vitamin D
Megjelenés:	International Journal of Cardiology 230 (2017), p. 577-584. -
További szerzők:	Annweiler, Cedric Duval, Guillaume Karras, Spyridon Tirabassi, Giacomo Salvio, Gianmaria Balercia, Giancarlo Kimball, Samantha Kotsa, Kalliopi Mascitelli, Luca Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Colao, Annamaria
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001-es BibID:	BIBFORM065416
Első szerző:	Muscogiuri, Giovanna
Cím:	Vitamin D and chronic diseases : the current state of the art / Giovanna Muscogiuri, Barbara Altieri, Cedric Annweiler, Giancarlo Balercia, Harjit Pal Bhattoa, Barbara J. Boucher, John J. Cannell, Carlo Foresta, Martin R. Grübler, Kalliopi Kotsa, Luca Mascitelli, Winfried März, Francesco Orio, Stefan Pilz, Giacomo Tirabassi, Annamaria Colao
Dátum:	2017
ISSN:	0340-5761
Megjegyzések:	The objective was to provide the current state ofthe art regarding the role of vitamin D in chronic diseases(osteoporosis, cancer, cardiovascular diseases, dementia,autism, type 1 and type 2 diabetes mellitus, male andfemale fertility). The document was drawn up by paneliststhat provided their contribution according to their own scientificexpertise. Each scientific expert supplied a first draftmanuscript on a specific aspect of the document's topic thatwas subjected to voting by all experts as "yes" (agreementwith the content and/or wording) or "no" (disagreement). The adopted rule was that statements supported by ?75 %of votes would be immediately accepted, while those with<25 % would be rejected outright. Others would be subjectedto further discussion and subsequent voting, where?67 % support or, in an eventual third round, a majorityof ?50 % would be needed. This document finds thatthe current evidence support a role for vitamin D in bonehealth but not in other health conditions. However, subjectswith vitamin D deficiency have been found to be at highrisk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommendvitamin D supplementation as treatment of chronicdiseases, the treatment of vitamin D deficiency shouldbe desiderable in order to reduce the risk of developingchronic diseases.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Vitamin D Musculoskeletal disorders Cancer cardiovascular diseases Dementia autism diabetes mellitus hypogonadism Fertility PCOS Environment Lifestyle Endometriosis
Megjelenés:	Archives Of Toxicology 91 : 1 (2017), p. 97-107. -
További szerzők:	Altieri, Barbara Annweiler, Cedric Balercia, Giancarlo Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Boucher, Barbara Cannell, John J. Foresta, Carlo Grübler, Martin R. Kotsa, Kalliopi Mascitelli, Luca März, Winfried Orio, Francesco Pilz, Stefan Tirabassi, Giacomo Colao, Annamaria
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