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001-es BibID:BIBFORM067628
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Vitamin D : musculoskeletal health / Harjit Pal Bhattoa, Jerzy Konstantynowicz, Natalia Laszcz, Marek Wojcik, Pawel Pludowski
Dátum:2017
Megjegyzések:Perhaps the role of Vitamin D supplementation has been most exhaustively studied in calcium absorption, skeletal wellbeing, muscular potency, balance and risk of falling. Nonetheless, new data has emerged and the recent research on sarcopenia makes the topic increasingly interesting. Given the socioeconomic burden of the musculoskeletal consequences of hypovitaminosis D it is vital to keep abreast with the latest literature in the field. The recommended Vitamin D supplementation dose should suffice to increase the serum 25 hydroxyvitamin D level to 30 ng/mL (75 nmol/L) and this level should be optimally maintained with a maintenance dose, particularly for those diagnosed with osteoporosis.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Vitamin D
Bone
Muscle
Osteoporosis
Falls
Sarcopenia
Megjelenés:Reviews in Endocrine and Metabolic Disorders 18 : 3 (2017), p. 363-371. -
További szerzők:Konstantynowicz, Jerzy Laszcz, Natalia Wojcik, Marek Pludowski, Pawel
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2.

001-es BibID:BIBFORM067627
Első szerző:Pludowski, Pawel
Cím:Vitamin D supplementation guidelines / Pawel Pludowski, Michael F. Holick, William B. Grant, Jerzy Konstantynowicz, Mario R. Mascarenhas, Afrozul Haq, Vladyslav Povoroznyuk, Nataliya Balatska, Ana Paula Barbosa, Tatiana Karonova, Ema Rudenka, Waldemar Misiorowski, Irina Zakharova, Alena Rudenka, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Natalia Laszcz, Pawel Abramowicz, Harjit P. Bhattoa, Sunil J. Wimalawansa
Dátum:2018
Megjegyzések:Research carried out during the past two-decades extended the understanding of actions of vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many pleiotropic actions in organs and tissues in the body. Most observational and ecological studies report association of higher serum 25-hydroxyvitamin D [25(OH)D] concentrations with improved outcomes for several chronic, communicable and non-communicable diseases. Consequently, numerous agencies and scientific organizations have developed recommendations for vitamin D supplementation and guidance on optimal serum 25(OH)D concentrations. The bone-centric guidelines recommend a target 25(OH)D concentration of 20 ng/mL (50 nmol/L), and age-dependent daily vitamin D doses of 400?800 IU. The guidelines focused on pleiotropic effects of vitamin D recommend a target 25(OH)D concentration of 30 ng/mL (75 nmol/L), and age-, body weight-, disease-status, and ethnicity dependent vitamin D doses ranging between 400 and 2000 IU/day. The wise and balanced choice of the recommendations to follow depends on one's individual health outcome concerns, age, body weight, latitude of residence, dietary and cultural habits, making the regional or nationwide guidelines more applicable in clinical practice. While natural sources of vitamin D can raise 25(OH)D concentrations, relative to dietary preferences and latitude of residence, in the context of general population, these sources are regarded ineffective to maintain the year-round 25(OH)D concentrations in the range of 30?50 ng/mL (75?125 nmol/L). Vitamin D self-administration related adverse effects, such as hypercalcemia and hypercalciuria are rare, and usually result from taking extremely high doses of vitamin D for a prolonged time.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Vitamin D
25(OH)D
Pleiotropic
Extra-skeletal effects
Global
Recommendations
Megjelenés:The Journal of Steroid Biochemistry and Molecular Biology 175 (2018), p. 125-135. -
További szerzők:Holick, Michael F. Grant, William B. Konstantynowicz, Jerzy Mascarenhas, Mario R. Haq, Afrozul Povoroznyuk, Vladyslav Balatska, Nataliya Barbosa, Ana Paula Karonova, Tatiana Rudenka, Ema Misiorowski, Waldemar Zakharova, Irina Rudenka, Alena Łukaszkiewicz, Jacek Marcinowska-Suchowierska, Ewa Laszcz, Natalia Abramowicz, Pawel Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Wimalawansa, Sunil J.
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Intézményi repozitóriumban (DEA) tárolt változat
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