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001-es BibID:BIBFORM081578
035-os BibID:(PMID)30963976
Első szerző:Muscogiuri, Giovanna
Cím:Calcium and Vitamin D Supplementation : myths and Realities with Regard to Cardiovascular Risk / Giovanna Muscogiuri, Luigi Barrea, Barbara Altieri, Carolina Di Somma, Harjit Pal Bhattoa, Daniela Laudisio, Guillaume T. Duval, Gabriella Pugliese, Cédric Annweiler, Francesco Orio, Hana Fakhouri, Silvia Savastano, Annamaria Colao
Dátum:2019
ISSN:1570-1611
Megjegyzések:Vitamin D and calcium are considered crucial for the treatment of bone diseases. Both vitamin D and calcium contribute to bone homeostasis but also preserve muscle health by reducing the risk of falls and fractures. Low vitamin D concentrations result in secondary hyperparathyroidism and contribute to bone loss, although the development of secondary hyperparathyroidism varies, even in patients with severe vitamin D deficiency. Findings from observational studies have shown controversial results regarding the association between bone mineral density and vitamin D/calcium status, thus sparking a debate regarding optimum concentrations of 25-hydroxyvitamin D and calcium for the best possible skeletal health. Although most of the intervention studies reported a positive effect of supplementation with calcium and vitamin D on bone in patients with osteoporosis, this therapeutic approach has been a matter of debate regarding potential side effects on the cardiovascular (CV) system. Thus, the aim of this review is to consider the current evidence on the physiological role of vitamin D and calcium on bone and muscle health. Moreover, we provide an overview on observational and interventional studies that investigate the effect of vitamin D and calcium supplementation on bone health, also taking into account the possible CV side-effects. We also provide molecular insights on the effect of calcium plus vitamin D on the CV system.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Vitamin D
bone health
calcium
cardiovascular system
myocardial infarction
stroke
Megjelenés:Current Vascular Pharmacology. - 17 : 6 (2019), p. 610-617. -
További szerzők:Barrea, Luigi Altieri, Barbara Di Somma, Carolina Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Laudisio, Daniela Duval, Guillaume Pugliese, Gabriella Annweiler, Cedric Orio, Francesco Fakhoury, Hana M. A. Savastano, Silvia Colao, Annamaria
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001-es BibID:BIBFORM067623
Első szerző:Muscogiuri, Giovanna
Cím:Vitamin D and cardiovascular disease : from atherosclerosis to myocardial infarction and stroke / Giovanna Muscogiuri, Cedric Annweiler, Guillaume Duval, Spyridon Karras, Giacomo Tirabassi, Gianmaria Salvio, Giancarlo Balercia, Samantha Kimball, Kalliopi Kotsa, Luca Mascitelli, Harjit Pal Bhattoa, Annamaria Colao
Dátum:2017
ISSN:0167-5273
Megjegyzések:There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). In fact vitamin D deficiency has been associated to an increased risk of developing CVD given to the relationship between low vitamin D levels and obesity, diabetes mellitus, dyslipidaemia, endothelial dysfunction and hypertension. However, although vitamin D has been identified as a potentially important marker of CVD, the mechanisms through which vitamin D deficiency leads from endothelial dysfunction to myocardial infarction and stroke are not fully understood. Thus, the goal of this review is to provide an updated review of the literature on the basic science of how vitamin D may affect the cardiovascular system and in particular to analyze the role that vitamin D may have in the whole dynamic process from the initiation of endothelial dysfunction to the development of myocardial infarction and stroke.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Atherosclerosis
Environment
Lifestyle
Myocardial infarction
Stroke
Vitamin D
Megjelenés:International Journal of Cardiology 230 (2017), p. 577-584. -
További szerzők:Annweiler, Cedric Duval, Guillaume Karras, Spyridon Tirabassi, Giacomo Salvio, Gianmaria Balercia, Giancarlo Kimball, Samantha Kotsa, Kalliopi Mascitelli, Luca Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Colao, Annamaria
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Intézményi repozitóriumban (DEA) tárolt változat
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