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001-es BibID:BIBFORM082799
035-os BibID:(PMID)31907366
Első szerző:Altieri, Barbara
Cím:Vitamin D testing : advantages and limits of the current assays / Barbara Altieri, Etienne Cavalier, Harjit Pal Bhattoa, Faustino R. Pérez-López, María T. López-Baena, Gonzalo R. Pérez-Roncero, Peter Chedraui, Cedric Annweiler, Silvia Della Casa, Sieglinde Zelzer, Markus Herrmann, Antongiulio Faggiano, Annamaria Colao, Michael F. Holick
Dátum:2020
ISSN:0954-3007
Megjegyzések:Vitamin D deficiency and insufficiency has become a pandemic health problem with a consequent increase of requests for determining circulating levels of 25-hydroxyvitamin D [25(OH)D]. However, the analytical performance of these immunoassays, including radioimmunoassay and ELISA, is highly variable, and even mass spectrometric methods, which nowadays serves as the gold standard for the quantitatively determination of 25(OH)D, do not necessarily produce comparable results, creating limitations for the definition of normal vitamin D status ranges. To solve this problem, great efforts have been made to promote standardization of laboratory assays, which is important to achieve comparable results across different methods and manufacturers. In this review, we performed a systematic analysis evaluating critically the advantages and limits of the current assays available for the measure of vitamin D status, i.e., circulating 25(OH)D and its metabolites, making suggestions that could be used in the clinical practice. Moreover, we also suggest the use of alternatives to blood test, including standardized surveys that may be of value in alerting health-care professionals about the vitamin D status of their patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Journal Of Clinical Nutrition. - 74 : 2 (2020), p. 231-247. -
További szerzők:Cavalier, Etienne Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Pérez-López, Faustino R. López-Baena, María T. Pérez-Roncero, Gonzalo R. Chedraui, Peter Annweiler, Cedric Della Casa, Silvia Zelzer, Sieglinde Herrmann, Markus Faggiano, Antongiulio Colao, Annamaria Holick, Michael F.
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001-es BibID:BIBFORM067627
Első szerző:Pludowski, Pawel
Cím:Vitamin D supplementation guidelines / Pawel Pludowski, Michael F. Holick, William B. Grant, Jerzy Konstantynowicz, Mario R. Mascarenhas, Afrozul Haq, Vladyslav Povoroznyuk, Nataliya Balatska, Ana Paula Barbosa, Tatiana Karonova, Ema Rudenka, Waldemar Misiorowski, Irina Zakharova, Alena Rudenka, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Natalia Laszcz, Pawel Abramowicz, Harjit P. Bhattoa, Sunil J. Wimalawansa
Dátum:2018
Megjegyzések:Research carried out during the past two-decades extended the understanding of actions of vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many pleiotropic actions in organs and tissues in the body. Most observational and ecological studies report association of higher serum 25-hydroxyvitamin D [25(OH)D] concentrations with improved outcomes for several chronic, communicable and non-communicable diseases. Consequently, numerous agencies and scientific organizations have developed recommendations for vitamin D supplementation and guidance on optimal serum 25(OH)D concentrations. The bone-centric guidelines recommend a target 25(OH)D concentration of 20 ng/mL (50 nmol/L), and age-dependent daily vitamin D doses of 400?800 IU. The guidelines focused on pleiotropic effects of vitamin D recommend a target 25(OH)D concentration of 30 ng/mL (75 nmol/L), and age-, body weight-, disease-status, and ethnicity dependent vitamin D doses ranging between 400 and 2000 IU/day. The wise and balanced choice of the recommendations to follow depends on one's individual health outcome concerns, age, body weight, latitude of residence, dietary and cultural habits, making the regional or nationwide guidelines more applicable in clinical practice. While natural sources of vitamin D can raise 25(OH)D concentrations, relative to dietary preferences and latitude of residence, in the context of general population, these sources are regarded ineffective to maintain the year-round 25(OH)D concentrations in the range of 30?50 ng/mL (75?125 nmol/L). Vitamin D self-administration related adverse effects, such as hypercalcemia and hypercalciuria are rare, and usually result from taking extremely high doses of vitamin D for a prolonged time.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Vitamin D
25(OH)D
Pleiotropic
Extra-skeletal effects
Global
Recommendations
Megjelenés:The Journal of Steroid Biochemistry and Molecular Biology 175 (2018), p. 125-135. -
További szerzők:Holick, Michael F. Grant, William B. Konstantynowicz, Jerzy Mascarenhas, Mario R. Haq, Afrozul Povoroznyuk, Vladyslav Balatska, Nataliya Barbosa, Ana Paula Karonova, Tatiana Rudenka, Ema Misiorowski, Waldemar Zakharova, Irina Rudenka, Alena Łukaszkiewicz, Jacek Marcinowska-Suchowierska, Ewa Laszcz, Natalia Abramowicz, Pawel Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Wimalawansa, Sunil J.
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