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001-es BibID:	BIBFORM048832
035-os BibID:	PMID:23836684
Első szerző:	Nilius, Bernd
Cím:	TRPV3 : time to decipher a poorly understood family member! / Bernd Nilius, Tamás Bíró, Grzegorz Owsianik
Dátum:	2014
ISSN:	0022-3751
Megjegyzések:	TThe vanilloid transient receptor potential channel TRPV3 differs in several aspects from other members of the TRPV subfamily. This Ca2+, ATP and calmodulin regulated channel constitutes a target for many natural compounds and has a unique expression pattern as the most prominent and important TRP channel in keratinocytes of the skin. Although TRPV3 is considered as a thermosensitive channel, its function as a thermosensor in the skin is challenged. Nevertheless, it plays important roles in other skin functions such as cutaneous sensations, hair development and barrier function. More recently, mutations in TRPV3 were linked with a rare genodermatosis known as the Olmsted syndrome. This review gives an overview on properties of TRPV3 and its functions in the skin and skin diseases.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Calcium (Ca2+) signalling Ion channel Membrane transport Molecular mechanisms of disease Skin TRP channels
Megjelenés:	Journal of Physiology. - 592 (2014), p. 295-304. -
További szerzők:	Bíró Tamás (1968-) (élettanász) Owsianik, Grzegorz
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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