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1.

001-es BibID:BIBFORM066281
Első szerző:Balogh Enikő (molekuláris biológus)
Cím:Impaired Immunosuppressive Effect of Bronchoalveolar Mesenchymal Stem Cells in Hypersensitivity Pneumonitis : preliminary findings / Eniko Balogh, Bela Nagy Jr., Agnes Gyetvai, Zsolt Bene, Zoltan Hendrik, Viktoria Jeney, Peter Nagy, Agnes Papp, Jozsef Balla, Gyorgy Balla, Janos Kappelmayer, Bela Nagy
Dátum:2018
ISSN:1552-4949
Megjegyzések:Bronchoalveolar mesenchymal stem cells (MSCs) play an important role in the maintenance of lung integrity. Therapeutic application of bone marrow-derived MSCs reduced chronic bronchial inflammation in idiopathic pulmonary fibrosis, and improved the ratio of survivors in sepsis with pneumonia. This study investigated the effect of MSCs from bronchoalveolar lavage fluid (BALF) of hypersensitivity pneumonitis (HP) on T-cell function under in vitro conditions.METHODS:Bronchoalveolar MSCs were obtained via bronchoscopy with BAL from children with severe subacute HP. As control, BALF MSCs were assessed from children without any inflammatory lung disease. Isolated MSCs were characterized via immunophenotyping by flow cytometry and confocal laser scanning microscopy. HP-derived and healthy separated peripheral blood mononuclear cells (PBMCs) were stimulated by 5 ?g/mL phytohemagglutinin in the presence of HP-derived or control MSCs in 5-day cultures. Proliferation and activation of T-cells were characterized by the mean fluorescence intensity (MFI) of 5,6-carboxyfluorescein-diacetat succinimidyl ester (CFSE) and CD25, CD69 as well as HLA-DR surface positivities, respectively.RESULTS:HP-derived MSCs showed significantly lower level of CD73, CD90, and CD105 expression compared to control MSCs in both flow cytometric and confocal microscopic experiments. MSCs from HP did not reduce T-cell proliferation based on CFSE MFI values, while the level of CD25 expression on both control and HP-derived CD4+ and CD8+ T-cells was significantly reduced by normal MSCs, while HP-derived MSCs did not have any significant effect. The level of other activation markers was not markedly modulated by MSCs.CONCLUSIONS:BALF MSCs from HP are unable to downregulate the proliferation and activation of T-cells that may support the development of recurrent intrapulmonary inflammation in HP. ? 2016 Clinical Cytometry Society.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
T-lymphocyte proliferation and activation
bronchoalveolar lavage
hypersensitivity pneumonitis
mesenchymal stem cells
Megjelenés:Cytometry Part B-Clinical Cytometry. - 94 : 2 (2018), p. 363-368. -
További szerzők:Nagy Béla Jr. (1980-) (labordiagnosztikai szakorvos) Gyetvai Ágnes Bene Zsolt (1981-) (orvos) Hendrik Zoltán (1986-) (orvos) Jeney Viktória (1971-) (vegyész, kémia tanár) Nagy Péter (1971-) (biofizikus) Papp Ágnes (1967-) (gyermekgyógyász, pulmonológus) Balla József (1959-) (belgyógyász, nephrológus) Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus) Kappelmayer János (1960-) (laboratóriumi szakorvos) Nagy Béla (1949-) (csecsemő- és gyermekgyógyász, gyermek-tüdőgyógyász)
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2.

001-es BibID:BIBFORM118662
035-os BibID:(WoS)001161390600001 (Scopus)85185143533
Első szerző:Baráth Sándor (biológus)
Cím:Enhancing HLA-B27 antigen detection : Leveraging machine learning algorithms for flow cytometric analysis / Baráth Sándor, Singh Parvind, Hevessy Zsuzsanna, Ujfalusi Anikó, Mezei Zoltán, Balogh Mária, Száraz Széles Marianna, Kappelmayer János
Dátum:2024
ISSN:1552-4949
Megjegyzések:As the association of human leukocyte antigen B27 (HLA-B27) with spondylarthropathies is widely known, HLA-B27 antigen expression is frequently identified using flow cytometric or other techniques. Because of the possibility of cross-reaction with off target antigens, such as HLA-B7, each flow cytometric technique applies a "gray zone" reserved for equivocal findings. Our aim was to use machine learning (ML) methods to classify such equivocal data as positive or negative. Equivocal samples (n = 99) were selected from samples submitted to our institution for clinical evaluation by HLA-B27 antigen testing. Samples were analyzed by flow cytometry and polymerase chain reaction. Features of histograms generated by flow cytometry were used to train and validate ML methods for classification as logistic regression (LR), decision tree (DT), random forest (RF) and light gradient boost method (GBM). All evaluated ML algorithms performed well, with high accuracy, sensitivity, specificity, as well as negative and positive predictive values. Although, gradient boost approaches are proposed as high performance methods; nevertheless, their effectiveness may be lower for smaller sample sizes. On our relatively smaller sample set, the random forest algorithm performed best (AUC: 0.92), but there was no statistically significant difference between the ML algorithms used. AUC values for light GBM, DT, and LR were 0.88, 0.89, 0.89, respectively. Implementing these algorithms into the process of HLA-B27 testing can reduce the number of uncertain, false negative or false positive cases, especially in laboratories where no genetic testing is available.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Cytometry Part B-Clinical Cytometry. - [Epub ahead of print] (2024). -
További szerzők:Singh, Parvind (1995-) (PhD hallgató) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) Ujfalusi Anikó (1968-) (gyermekorvos, laboratóriumi szakorvos) Mezei Zoltán András (1980-) (orvos) Balogh Mária Széles Mariann Kappelmayer János (1960-) (laboratóriumi szakorvos)
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3.

001-es BibID:BIBFORM077170
Első szerző:Bekéné Debreceni Ildikó (biológus)
Cím:L-Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia / Beke Debreceni Ildikó, Szász Róbert, Kónya Zoltán, Erdődi Ferenc, Kiss Flóra, Kappelmayer János
Dátum:2019
ISSN:1552-4949
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cytometry Part B-Clinical Cytometry. - 96 : 2 (2019), p. 149-157. -
További szerzők:Szász Róbert (1972-) (belgyógyász, haematológus) Kónya Zoltán (1986-) (molekuláris biológus, biokémikus) Erdődi Ferenc (1953-) (biokémikus) Kiss Flóra (1980-) (bőrgyógyász) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Pályázati támogatás:GINOP-2.3.2-15-2016-00043
GINOP
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4.

001-es BibID:BIBFORM024616
Első szerző:Csáthy László (laboratóriumi szakorvos)
Cím:Classical and atypical neuroblastoma : case reports / Csáthy L., Kappelmayer J., Szegedi I., Kajtár B., Kiss Cs., Hevessy Z.
Dátum:2011
Megjegyzések:Neuroblastoma is the most common extracranial solid tumor in early childhood with a pluripotent neural cell origin. The disease often infiltrates the bone marrow, and these cases are candidates for flow cytometric diagnosis and disease follow-up, more so in atypical cases that are diagnostically challenging by other methods. Here, we report two neuroblastoma cases, one with characteristic neuroblastoma cells forming Homer-Wright rosettes found in the bone marrow sample by histological examination. This case showed the classical immunophenotype with CD81/CD56/CD117 positive and CD45 negative labeling and 80% bone marrow infiltration. Minimal residual disease measurement was performed in a regular fashion, and flow cytometry results showed good correlation with other disease markers. Analyzing 300,000 events provided a sensitivity level of 0.01%. The second case showed atypical cell morphology on histological examination, after which flow cytometric analysis was initiated. Atypical cells displayed CD81 and bright CD56 but CD117 negative immunophenotype, with a 28% bone marrow infiltration. In most cases the primary tumor can be identified, but in this particular case only bone marrow involvement could be detected using flow cytometry, as such making it a powerful tool for diagnosis and disease monitoring.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cytometry. Part B, Clinical Cytometry. - 80B : 2 (2011), p. 134-136. -
További szerzők:Kappelmayer János (1960-) (laboratóriumi szakorvos) Szegedi István (1969-) (hematológus, onkológus, nefrológus) Kajtár Béla (1977-) (patológus) Kiss Csongor (1956-) (hematológus, onkológus) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos)
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DOI
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5.

001-es BibID:BIBFORM020763
035-os BibID:(scopus)80051910015 (wos)000294938700008
Első szerző:Imre László (biológus)
Cím:Detection of mutations by flow cytometric melting point analysis of PCR products / Imre L., Balogh I., Kappelmayer J., Szabó M., Melegh B., Wanker E., Szabó G.
Dátum:2011
Megjegyzések:Exploring the possibilities offered by flow cytometric microbead analyses for the detection of genetic alterations, an assay based on the dependence of the melting point of double-stranded DNA molecules on their length has been developed, making use of PCR products carrying biotin and fluorescent moiety on their two ends. The samples of different length PCR products immobilized on streptavidine coated microbeads are heat-treated in the presence of formamide at temperatures between the melting point of the longer and that of the shorter PCR product, when the mean fluorescence intensity of the beads carrying the shorter molecules decreases as a result of denaturation, as opposed to the sample containing the longer product. The efficacy and sensitivity of the method is demonstrated in the case of the assessment of the degree of triplet expansion in Huntington's disease. Its utility for the detection of point mutations in heterozygous clinical samples is shown in the case of the BRCA1 gene. The assay is simple and may be offered for the purposes of clinical diagnostics of a number of genetic conditions. These include screening of samples for triplet expansions and SNPs predisposing for particular pathological or pharmacogenomic conditions. In general, the method described herein is offered for the diagnosis of any pathological condition where the length of a genomic or cDNA sequence is expected to be different from that of the normal allele
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
analysis
article
Biophysics
diagnosis
Dna
FLOW
Fluorescence
Hungary
Mutation
Point Mutation
Research
Research Support
Support
Temperature
Megjelenés:Cytometry. Part A. - 79 : 9 (2011), p. 720-726. -
További szerzők:Balogh István (1972-) (molekuláris biológus, genetikus) Kappelmayer János (1960-) (laboratóriumi szakorvos) Szabó Miklós Melegh Béla Wanker Erich Szabó Gábor (1953-) (biofizikus)
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Intézményi repozitóriumban (DEA) tárolt változat
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6.

001-es BibID:BIBFORM106751
035-os BibID:(scopus)85142178739
Első szerző:Kappelmayer János (laboratóriumi szakorvos)
Cím:Issue highlights - November 2022 / Kappelmayer János
Dátum:2022
ISSN:1552-4949
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Cytometry Part B-Clinical Cytometry. - 102 : 6 (2022), p. 425-426. -
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7.

001-es BibID:BIBFORM054370
Első szerző:Kappelmayer János (laboratóriumi szakorvos)
Cím:Clinical Cytometry in Europe, 2007 / Janos Kappelmayer, Maria Arroz, Bruno Brando, Ingmar A. Heijnen, Ellen Kuiper-Kramer, Stefano Papa, Jan Philippe, Frank W. Preijers, Gregor Rothe, Jan W. Gratama
Dátum:2007
ISSN:1552-4949
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Megjelenés:Cytometry. Part B, Clinical Cytometry. - 74B (2007), p. 45-46. -
További szerzők:Arroz, Maria Brando, Bruno Heijnen, Ingmar A. Kuiper-Kramer, Ellen Papa, Stefano Philippe, Jan Preijers, Frank W. Rothe, Gregor Gratama, Jan Willem
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8.

001-es BibID:BIBFORM062383
Első szerző:Kerényi Adrienne (laboratóriumi szakorvos)
Cím:Evaluation of flow cytometric HIT assays in relation to an IgG-specific immunoassay and clinical outcome / Adrienne Kerényi, Ildikó Beke Debreceni, Zsolt Oláh, Péter Ilonczai, Zsuzsanna Bereczky, Béla Nagy Jr., László Muszbek, János Kappelmayer
Dátum:2017
ISSN:1552-4949
Megjegyzések:BACKGROUND:Heparin-induced thrombocytopenia (HIT) is a severe side effect of heparin treatment caused by platelet activating IgG antibodies generated against the platelet factor 4 (PF4)-heparin complex. Thrombocytopenia and thrombosis are the leading clinical symptoms of HIT.METHODS:The clinical pretest probability of HIT was evaluated by the 4T score system. Laboratory testing of HIT was performed by immunological detection of antibodies against PF4-heparin complex (EIA) and two functional assays. Heparin-dependent activation of donor platelets by patient plasma was detected by flow cytometry. Increased binding of Annexin-V to platelets and elevated number of platelet-derived microparticles (PMP) were the indicators of platelet activation.RESULTS:EIA for IgG isotype HIT antibodies was performed in 405 suspected HIT patients. Based on negative EIA results HIT was excluded in 365 (90%) of cases. In 40 patients with positive EIA test result functional tests were performed. Platelet activating antibodies were detected in 17 cases by Annexin V binding. PMP count analysis provided nearly identical results. The probability of a positive flow cytometric assay result was higher in patients with elevated antibody titer. 71% of patients with positive EIA and functional assay had thrombosis.CONCLUSIONS:EIA is an important first line laboratory test in the diagnosis of HIT, however, HIT must be confirmed by a functional test. Annexin V binding and PMP assays using flow cytometry are functional HIT tests convenient in a clinical diagnostic laboratory. The positive results of functional assays may predict the onset of thrombosis. This article is protected by copyright. All rights reserved.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
heparin-induced thrombocytopenia
thrombosis
4T score
flow cytometry
platelet microparticles
Megjelenés:Cytometry Part B-Clinical Cytometry. - 92 : 5 (2017), p. 389-397. -
További szerzők:Bekéné Debreceni Ildikó (1970-) (biológus) Oláh Zsolt (1974-) (belgyógyász) Ilonczai Péter (1977-) (orvos, belgyógyász, haematológus szakorvos) Bereczky Zsuzsanna (1974-) (orvosi laboratóriumi diagnosztika szakorvos) Nagy Béla Jr. (1980-) (labordiagnosztikai szakorvos) Muszbek László (1942-) (haematológus, kutató orvos) Kappelmayer János (1960-) (laboratóriumi szakorvos)
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9.

001-es BibID:BIBFORM005605
Első szerző:Kiss Flóra (bőrgyógyász)
Cím:A coagulation factor becomes useful in the study of acute leukemias : studies with blood coagulation factor XIII / Kiss F., Simon Á., Csáthy L., Hevessy Z., Katona É., Kiss C., Kappelmayer J.
Dátum:2008
Megjegyzések:The intracellular form of the coagulation factor XIII has previously been identified by immunomorphological techniques using polyclonal antibodies. In these studies, only the A subunit (FXIII-A) was detectable in megakaryocytes/platelets and in monocytes/ macrophages. We developed several novel monoclonal antibody clones directed to both subunits (FXIII-A and FXIII-B) and investigated their appearance in normal and leukemic cells. By using 3- and 4-color flow cytometry FXIII expression was investigated in normal peripheral blood and bone marrow samples and in acute myeloblastic (AML) and lymphoblastic (ALL) leukemia cases. Samples were studied by Western blotting and confocal laser scanning microscopy. With a previously published ELISA assay applying two monoclonal antibodies directed to different epitopes in FXIII-A, we were able to measure the intracytoplasmic content of FXIII-A in normal cells and leukemic blasts. FXIII-A was detectable in normal peripheral blood monocytes and in large quantities in platelets, but both cell types were negative for FXIII-B. There was no surface staining for FXIII-A, it only appeared intracellularly. In samples derived from patients with AML M4 and M5, FXIII-A sensitively identified blast cells. Although normal lymphocytes do not express FXIII-A, 40% of ALL cases showed significant FXIII-A expression as determined by flow cytometry. FXIII-A positivity of lymphoblasts was verified by Western blotting, ELISA, and confocal laser scanning microscopy cytometry. These data provide evidence that FXIII-A is a sufficiently sensitive marker in differentiating myeloblasts and monoblasts and is suitable for identifying leukemia-associated phenotypes in ALL.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
factor XIII
flow cytometry
acute leukemia phenotype
Megjelenés:Cytometry. Part A. - 73A : 3 (2008), p. 194-201. -
További szerzők:Simon Ágnes (1969-) (laboratóriumi szakorvos) Csáthy László (1979-) (laboratóriumi szakorvos) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) Katona Éva (1961-) (klinikai biokémikus) Kiss Csongor (1956-) (hematológus, onkológus) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Internet cím:DOI
elektronikus változat
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10.

001-es BibID:BIBFORM004883
035-os BibID:(WOS)000233027300007 (scopus)27644433274
Első szerző:Pataki Judit (biofizikus)
Cím:Biological microbeads for flow-cytometric immunoassays, enzyme titrations, and quantitative PCR / Pataki, J., Szabo, M., Lantos, E., Szekvolgyi, L., Molnar, M., Hegedus, E., Bacso, Z., Kappelmayer, J., Lustyik, G., Szabo, G.
Dátum:2005
ISSN:1552-4922
Megjegyzések:Introduction of microbeads into flow-cytometry has created a new scenario, making quantitative measurement of molecules dispersed in a homogeneous phase, with an extremely wide realm of already realized and potential applications possible. Development of this field has lead to specialized instrumentation and microbead arrays, dedicated to certain applications. METHODS: Formaldehyde-fixed yeast and bacterial cells were conjugated with avidin and applied as microbeads, to establish a simple, convenient, flexible, and inexpensive flow-cytometric platform for various immunological and biochemical assays. RESULTS: We have tested these "biological microbeads" for the simultaneous titration of human alpha-fetoprotein (AFP) and human Chorionic Gonadotropin (betahCG) hormone levels, for the titration of proteolytic and nucleolytic (restriction) enzymes, and for quantitative PCR, using biotinylated and fluorescent primers. CONCLUSIONS: The use of biological microbeads for various immunological and biochemical assays has been demonstrated. The flow-cytometric methods proved to be at least as sensitive as the standard biochemical or immunological tests. For proteinase K activity measurements, a single enzyme molecule in the sample could be detected. The sensitivity, versatility, and low cost of the assays may advance flow-cytometry to become a central methodological platform in most laboratories. The biological microbeads offer virtually unlimited possibilities for fluorescent labeling (addressing), conjugation of ligand binding molecules, and they are easy to handle and perform well in a multiplex format
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
alpha-Fetoproteins
analysis
Avidin
Biophysics
Biotinylation
Caseins
Cells
chemistry
Chorionic Gonadotropin,beta Subunit,Human
Dna
DNA Restriction Enzymes
Dyes
Endopeptidase K
Enzymes
Flow Cytometry
Fluorescent Dyes
Formaldehyde
Human
Humans
Hungary
Immunoassay
instrumentation
methods
Microspheres
Polymerase Chain Reaction
Research
Saccharomyces cerevisiae
Staphylococcus aureus
Streptavidin
Support
Titrimetry
egyetemen (Magyarországon) készült közlemény
Megjelenés:Cytometry. Part A. - 68 : 1 (2005), p. 45-52. -
További szerzők:Szabó Miklós (vegyészmérnök) Lantos Erika Székvölgyi Lóránt (1977-) (biofizikus, biokémikus, sejtbiológus) Molnár Mónika (biofizikus) Hegedűs Éva (1978-) (biofizikus) Bacsó Zsolt (1963-) (biofizikus) Kappelmayer János (1960-) (laboratóriumi szakorvos) Lustyik György Szabó Gábor (1953-) (biofizikus)
Internet cím:elektronikus változat
DOI
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11.

001-es BibID:BIBFORM054361
Első szerző:Ratei, Richard
Cím:Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias / Richard Ratei, Leonid Karawajew, Francis Lacombe, Krystyna Jagoda, Giovanni Del Poeta, Jaco Kraan, Maria De Santiago, Janos Kappelmayer, Elisabeth Bjorklund, W.-D. Ludwig, Jan Gratama, Alberto Orfao, European Working Group of Clinical Cell Analysis (EWGCCA)
Dátum:2006
ISSN:1552-4949
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cytometry. Part B, Clinical Cytometry. - 70B : 1 (2006), p. 1-9. -
További szerzők:Karawajew, Leonid Lacombe, Francis Jagoda, Krystyna Del Poeta, Giovanni Kraan, Jaco De Santiago, Maria Kappelmayer János (1960-) (laboratóriumi szakorvos) Björklund, Elisabeth Ludwig, W. D. Gratama, Jan Willem Orfao, Alberto European Working Group of Clinical Cell Analysis (EWGCCA)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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12.

001-es BibID:BIBFORM034576
Első szerző:Simon Ágnes (laboratóriumi szakorvos)
Cím:Expression of coagulation factor XIII subunit A in acute promyelocytic leukemia / Ágnes Simon, Zsuzsa Bagoly, Zsuzsanna Hevessy, László Csáthy, Éva Katona, György Vereb, Anikó Ujfalusi, László Szerafin, László Muszbek, János Kappelmayer
Dátum:2012
ISSN:1552-4949
Megjegyzések:Leukemic cells often express markers which are not characteristic of their particular cell lineage. In this study we identified the "A" subunit of coagulation factor XIII (FXIII-A) in leukemic promyelocytes in de novo AML M3 cases. The cytoplasmic presence of factor XIII-A has previously been shown only in platelets/megakaryocytes and monocytes/macrophages. Furthermore, more recently we described the presence of FXIII-A in leukemic lymphoblasts. We studied 14 patients with this rare type of acute leukemia in a period of 4 years and investigated their bone marrow samples by 3-color flow cytometry upon diagnosis, mainly focusing on FXIII-A expression of leukemic cells. We detected FXIII-A also by ELISA, Western-blot and confocal laser scanning microscopy. This was a homogenous group of AML M3 patients with translocation t(15;17)(q22;q21) detected by fluorescence in situ hybridization (FISH). In 10 out of 14 samples, FXIII-A was detectable by flow cytometry and was coexpressed with markers characteristic for leukemic promyleocytes (CD45dim/CD13+/CD33+/CD117+/cyMPO+ and HLA-DR-/CD34-/CD14-/CD15-). Staining for the markers GPIIb and GPIX were negative, and FXIII-A was identified in the cytoplasm of the cells by confocal microscopy in a relatively high quantity, as measured by ELISA. By Western blot analysis we could identify FXIII-A in the native 82 kD form and in cleaved forms corresponding to cleavage products observed when purified FXIII-A was treated by human neutrophil elastase. Since normal promyelocytes were FXIII-A negative, this novel expression site of FXIII-A in AML M3 can be considered as a leukemia associated immunophenotype and may have pathophysiological significance.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Molekuláris Medicina
Megjelenés:Cytometry. Part B. Clinical Cytometry. - 82B : 4 (2012), p. 209-216. -
További szerzők:Bagoly Zsuzsa (1978-) (orvos) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos) Csáthy László (1979-) (laboratóriumi szakorvos) Katona Éva (1961-) (klinikai biokémikus) Vereb György (1965-) (biofizikus, orvos) Ujfalusi Anikó (1968-) (gyermekorvos, laboratóriumi szakorvos) Szerafin László (1958-) (belgyógyászat, haematológia, klinikai onkológia szakorvos) Muszbek László (1942-) (haematológus, kutató orvos) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Pályázati támogatás:TÁMOP-4.2.1/B-09/1/KONV-2010-0007
TÁMOP
Celluláris hematológia - immunológia
TÁMOP-4.2.1/B-09/1/KONV-2010-0007
TÁMOP
A véralvadás XIII-as faktorának (FXIII) struktúrája, funkciója, előfordulása egyéb testnedvekben és kapcsolata trombotikus megbetegedésekkel
Internet cím:DOI
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