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001-es BibID:BIBFORM111042
035-os BibID:(cikkazonosító)1484 (WoS)000987004100001 (Scopus)85159145210
Első szerző:Ilie, Daniela Elena
Cím:Kompetitive Allele Specific PCR Genotyping of 89 SNPs in Romanian Spotted and Romanian Brown Cattle Breeds and Their Association with Clinical Mastitis / Daniela Elena Ilie; Dinu Gavojdian; Szilvia Kusza; Radu Ionel Neamț; Alexandru Eugeniu Mizeranschi; Ciprian Valentin Mihali; Ludovic Toma Cziszter
Dátum:2023
ISSN:2076-2615
Megjegyzések:Mastitis is the most common production disease in the dairy sector worldwide, its incidence being associated with both cows` exposure to bacteria and the cows` genetic make-up for resistance to pathogens. The objective of our study was to analyse 89 missense SNPs belonging to six genes (CXCR2, CXCL8, TLR4, BRCA1, LTF, BOLA-DRB3), which were found to be associated with genetic resistance or susceptibility to mastitis. A total of 298 cattle (250 Romanian Spotted and 48 Romanian Brown) were genotyped by Kompetitive Allele Specific PCR (KASP) and a chi-squared test was used for genetic association studies with clinical mastitis. A total of 35 SNPs (39.3%) among the selected 89 SNPs were successfully genotyped, of which 31 markers were monomorphic. The polymorphic markers were found in two genes: TLR4 (rs460053411) and BOLA-DRB3 (rs42309897, rs208816121, rs110124025). The polymorphic SNPs with MAF > 5% and call rates > 95% were used for the association study. The results showed that rs110124025 in the BOLA-DRB3 gene was significantly associated with mastitis prevalence (p ? 0.05) in both investigated breeds. Current results show that the SNP rs110124025 in the BOLA-DRB3 gene can be used as a candidate genetic marker in selection for mastitis resistance in Romanian dairy cattle.
Tárgyszavak:Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
KASP
mastitis
polymorphism
Romanian Brown
Romanian Spotted
Megjelenés:Animals. - 13 : 9 (2023), p. 1-13. -
További szerzők:Gavojdian, Dinu Kusza Szilvia (1979-) (agrármérnök) Neamt, Radu Mizeranschi, Alexandru Eugeniu Ciprian, Valentin Mihali Cziszter, Ludovic Toma
Internet cím:DOI
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001-es BibID:BIBFORM106676
035-os BibID:(cikkazonosító)300 (WoS)000914082600001 (Scopus)85146777802
Első szerző:Wanjala, George (Animal scientist)
Cím:An on-station analysis of factors affecting growth traits of Pure Red Maasai and Dorper sheep breeds under an extensive production system / George Wanjala, Nelly Kichamu, Ludovic Toma Cziszter, Putri Kusuma Astuti, Szilvia Kusza
Dátum:2023
ISSN:2076-2615
Megjegyzések:This comparative study aimed to evaluate genetic and environmental factors` effects on thegrowth traits of lambs in Dorper and Red Maasai (RedM) sheep breeds. The data analyzed containedthe following measurements: birth weight (Bwt), weaning weight (Wwt), yearling weight (Ywt), birthtype (single or twins), and details on each lamb`s dam (dam ID and age) and sire. Except for the RedM,whose birth weight decreased with time, both breeds generally showed an increase in other growthweights across the study period, with yearly variations affecting both breeds. Additionally, analysis bya linear mixed model with restricted maximum likelihood (REML) showed that only breed as a factorsignificantly (p< 0.05) influenced birth weight; breed, sex, and birth type all significantly (p< 0.05)influenced weaning weight, whereas season, sex, and dam age significantly (p< 0.05) influencedyearling weight. The RedM breed outperformed the Dorper breed in post-weaning growth rate,demonstrating early resilience and adaptation to local environmental factors independent of maternalinfluence. Breed and non-genetic factors play a vital role in the growth of lambs, and the resultsof this study offer an opportunity for improved farm management under an extensive productionsystem and selection for the conservation of the indigenous Red Maasai breed.
Tárgyszavak:Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
weaning weight
yearling weight
growth traits
non-genetic factors
extensive production
Megjelenés:Animals. - 13 : 2 (2023), p. 1-10. -
További szerzők:Kichamu, Nelly (1978-) Cziszter, Ludovic Toma Astuti, Putri Kusuma (1994-) (állattenyésztési genetikus) Kusza Szilvia (1979-) (agrármérnök)
Pályázati támogatás:Tempus Public Foundation
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DOI
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