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001-es BibID:	BIBFORM108913
035-os BibID:	(cikkazonosító)103594 (WoS)000948491300001 (Scopus)85148660475
Első szerző:	Balog Katalin (állatgenetika)
Cím:	Application potential of chicken DNA chip in domestic pigeon species - preliminary results / Katalin Balog, Alexandru Eugeniu Mizeranschi, George Wanjala, Bíborka Sipos, Szilvia Kusza, Zoltán Bagi
Dátum:	2023
ISSN:	1319-562X 2213-7106
Megjegyzések:	Introducing the SNP technology to pigeon breeding will enhance the competitiveness of a sector that produces one of the healthiest and best quality meats. The present study aimed to test the applicability of the Illumina Chicken_50K_CobbCons array on 24 domestic pigeon individuals from the Mirthys hybrids and Racing pigeon breeds. A total of 53,313 SNPs were genotyped. Principal component analysis shows a significant overlap between the two groups. The chip performed poorly in this data set, with a call rate per sample of 0.474 (49%). The low call rate was likely due to an increase in the evolutionary distance. A total of 356 SNPs were retained after a relatively strict quality control. We have demonstrated that it is technically feasible to use a chicken microarray chip on pigeon samples. Presumably, with a larger sample size and by assigning phenotypic data, efficiency would be improved, allowing more thorough analyses, such as genome-wide association studies.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk DNA chip SNP-array Squab pigeon Racing pigeon Illumina Genotyping
Megjelenés:	Saudi Journal of Biological Sciences. - 30 : 3 (2023), p. 1-9. -
További szerzők:	Mizeranschi, Alexandru Eugeniu Wanjala, George (1984-) (Animal scientist) Sipos Bíborka (1996-) (állattenyésztő mérnök) Kusza Szilvia (1979-) (agrármérnök) Bagi Zoltán (1987-) (természetvédelmi mérnök, állatgenetika)
Pályázati támogatás:	ÚNKP-21-4 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM111042
035-os BibID:	(cikkazonosító)1484 (WoS)000987004100001 (Scopus)85159145210
Első szerző:	Ilie, Daniela Elena
Cím:	Kompetitive Allele Specific PCR Genotyping of 89 SNPs in Romanian Spotted and Romanian Brown Cattle Breeds and Their Association with Clinical Mastitis / Daniela Elena Ilie; Dinu Gavojdian; Szilvia Kusza; Radu Ionel Neamț; Alexandru Eugeniu Mizeranschi; Ciprian Valentin Mihali; Ludovic Toma Cziszter
Dátum:	2023
ISSN:	2076-2615
Megjegyzések:	Mastitis is the most common production disease in the dairy sector worldwide, its incidence being associated with both cows` exposure to bacteria and the cows` genetic make-up for resistance to pathogens. The objective of our study was to analyse 89 missense SNPs belonging to six genes (CXCR2, CXCL8, TLR4, BRCA1, LTF, BOLA-DRB3), which were found to be associated with genetic resistance or susceptibility to mastitis. A total of 298 cattle (250 Romanian Spotted and 48 Romanian Brown) were genotyped by Kompetitive Allele Specific PCR (KASP) and a chi-squared test was used for genetic association studies with clinical mastitis. A total of 35 SNPs (39.3%) among the selected 89 SNPs were successfully genotyped, of which 31 markers were monomorphic. The polymorphic markers were found in two genes: TLR4 (rs460053411) and BOLA-DRB3 (rs42309897, rs208816121, rs110124025). The polymorphic SNPs with MAF > 5% and call rates > 95% were used for the association study. The results showed that rs110124025 in the BOLA-DRB3 gene was significantly associated with mastitis prevalence (p ? 0.05) in both investigated breeds. Current results show that the SNP rs110124025 in the BOLA-DRB3 gene can be used as a candidate genetic marker in selection for mastitis resistance in Romanian dairy cattle.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk KASP mastitis polymorphism Romanian Brown Romanian Spotted
Megjelenés:	Animals. - 13 : 9 (2023), p. 1-13. -
További szerzők:	Gavojdian, Dinu Kusza Szilvia (1979-) (agrármérnök) Neamt, Radu Mizeranschi, Alexandru Eugeniu Ciprian, Valentin Mihali Cziszter, Ludovic Toma
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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