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001-es BibID:	BIBFORM069464
Első szerző:	Kappelmayer János (laboratóriumi szakorvos)
Cím:	Clinical laboratories : production factories or specialized diagnostic centers / János Kappelmayer, Judit Tóth
Dátum:	2016
Megjegyzések:	Since a large proportion of medical decisions arebased on laboratory results, clinical laboratoriesshould meet the increasing demand of clinicians andtheir patients. Huge central laboratories may processover 10 million tests annually; they act as productionfactories, measuring emergency and routinetests with sufficient speed and accuracy. At the sametime, they also serve as specialized diagnostic centerswhere well-trained experts analyze and interpretspecial test results. It is essential to improve andconstantly monitor this complex laboratory service,by several methods. Sample transport by pneumatictube system, use of an advanced laboratory informationsystem and point-of-care testing may result indecreased total turnaround time. The optimizationof test ordering may result in a faster and more costeffectivelaboratory service. Autovalidation can savetime for laboratory specialists, when the analysis ofmore complex results requires their attention. Smallteams of experts responsible for special diagnosticwork, and their interpretative reporting according topredetermined principles, may help to minimize subjectivityof these special reports. Although laboratoryinvestigations have become so diversely developed in the past decades, it is essential that the laboratorycan provide accurate results relativelyquickly, and that laboratory specialists can supportthe diagnosis and monitoring of patientsby adequate interpretation of esoteric laboratorymethods.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban turnaround time autovalidation interpretative results
Megjelenés:	The Electronic Journal of the International Federation of Clinical Chemistry and laboratory Medicine. - 27 : 2 (2016), p. 156-165. -
További szerzők:	Tóth Judit (1978-) (laboratóriumi szakorvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM091349
Első szerző:	Tóth Judit (laboratóriumi szakorvos)
Cím:	Detection of haemolysis, a frequent preanalytical problem in the serum of newborns and adults / Judit Tóth, Anna V. Oláh, Tamás Petercsák, Tamás Kovács, János Kappelmayer
Dátum:	2020
Megjegyzések:	Background: Preanalytical problems can be more frequent in case of preterm and term newborns as compared to the general patient population. Here we present the leading preanalytical errors in our laboratory, the prevalence of haemolysis and its impact on laboratory test results, and our efforts to improve the diagnostic workup of newborns' samples. Methods: Preanalytical quality indicators were analysed in all samples in 2018. The haemolysis index was measured spectrophotometrically in serum samples in the period of 2012-2018, and the ratio of haemolysed samples and the test rejection rates were analysed. The data of newborns and other patients were analysed separately. Results: During the tested year, the leading preanalytical errors were haemolysis in serum samples, inadequate sample identification and clotting of anticoagulated blood regarding all samples or newborns. In this seven-year period the ratio of haemolysed serum samples was 4.00% in all patients and 46.4% in newborns, while the test rejection rates due to haemolysis were 0.57% and 3.71%, respectively. Haemolysis indices were significantly higher in case of newborns than in patients with documented severe intravascular haemolysis which suggests that the major reason of elevated haemolysis indices in newborns was in vitro haemolysis. Accordingly, all C-reactive protein (CRP) results which were rejected by severe haemolysis became reliable after repeating blood sampling. Conclusion: Haemolysis is the leading preanalytical problem not only in newborns but also in the general patient population. Our study highlights the importance of automated assessment of serum indices and continuous monitoring of the preanalytical quality indicators and suggests the need for education and blood collection trainings.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Journal of the International Federation of Clinical Chemistry. - 31 : 1 (2020), p. 6-14. -
További szerzők:	Oláh Anna (1956-) (klinikai biokémikus, vegyész) Petercsák Tamás Kovács Tamás (1970-) (csecsemő és gyermekgyógyász, neonatológus) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat
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