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001-es BibID:	BIBFORM091349
Első szerző:	Tóth Judit (laboratóriumi szakorvos)
Cím:	Detection of haemolysis, a frequent preanalytical problem in the serum of newborns and adults / Judit Tóth, Anna V. Oláh, Tamás Petercsák, Tamás Kovács, János Kappelmayer
Dátum:	2020
Megjegyzések:	Background: Preanalytical problems can be more frequent in case of preterm and term newborns as compared to the general patient population. Here we present the leading preanalytical errors in our laboratory, the prevalence of haemolysis and its impact on laboratory test results, and our efforts to improve the diagnostic workup of newborns' samples. Methods: Preanalytical quality indicators were analysed in all samples in 2018. The haemolysis index was measured spectrophotometrically in serum samples in the period of 2012-2018, and the ratio of haemolysed samples and the test rejection rates were analysed. The data of newborns and other patients were analysed separately. Results: During the tested year, the leading preanalytical errors were haemolysis in serum samples, inadequate sample identification and clotting of anticoagulated blood regarding all samples or newborns. In this seven-year period the ratio of haemolysed serum samples was 4.00% in all patients and 46.4% in newborns, while the test rejection rates due to haemolysis were 0.57% and 3.71%, respectively. Haemolysis indices were significantly higher in case of newborns than in patients with documented severe intravascular haemolysis which suggests that the major reason of elevated haemolysis indices in newborns was in vitro haemolysis. Accordingly, all C-reactive protein (CRP) results which were rejected by severe haemolysis became reliable after repeating blood sampling. Conclusion: Haemolysis is the leading preanalytical problem not only in newborns but also in the general patient population. Our study highlights the importance of automated assessment of serum indices and continuous monitoring of the preanalytical quality indicators and suggests the need for education and blood collection trainings.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Journal of the International Federation of Clinical Chemistry. - 31 : 1 (2020), p. 6-14. -
További szerzők:	Oláh Anna (1956-) (klinikai biokémikus, vegyész) Petercsák Tamás Kovács Tamás (1970-) (csecsemő és gyermekgyógyász, neonatológus) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM061716
Első szerző:	Tóth Judit (laboratóriumi szakorvos)
Cím:	Pneumatic tube system for transport of laboratory samples: preanalytical aspects / Tóth Judit, Lenkey Ágota, V. Oláh Anna, Köteles Julianna, Kissné Sziráki Valéria, Kerényi Adrienne, Kappelmayer János
Dátum:	2014
ISSN:	0030-6002 1788-6120
Megjegyzések:	Introduction: A considerable proportion of laboratory errors occurs in the preanalytical phase. Aim: The aims of the authors were to study preanalytical errors in routine and emergency laboratory diagnostics in a regional clinical laboratory and evaluate the effect of the pneumatic tube system on turnaround time and laboratory results. Method: The ratio of preanalytical errors and reasons of test rejection were analysed. In addition, the effects of pneumatic tube and manual transport on the occurrence of hemolysis and platelet activation were compared. Results: Using the pneumatic tube transport system, preanalytical error was below 1%. The main causes of test rejection were haemolysis in case of serum samples, and clot formation and citrate excess in anticoagulated samples. The pneumatic tube transport resulted in significantly faster sample transport, more equalized sample arrival and processing, hence the turnaround time became shorter both for routine and emergency tests. Conclusions: Autovalidation and proper control of preanalytical errors are essential for rapid and reliable laboratory service supported by the pneumatic tube system for sample transport.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok magyar nyelvű folyóiratközlemény hazai lapban laboratóriumi diagnosztika preanalitikai hibák pneumatikus csőpostarendszer leletátfordulási időlaboratory diagnostics
Megjelenés:	Orvosi Hetilap. - 155 : 28 (2014), p. 1113-1120. -
További szerzők:	Lenkey Ágota (1944-) (biológus) Oláh Anna (1956-) (klinikai biokémikus, vegyész) Köteles Julianna Kissné Sziráki Valéria (1957-) (analitikus) Kerényi Adrienne (1970-) (laboratóriumi szakorvos) Kappelmayer János (1960-) (laboratóriumi szakorvos)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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