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001-es BibID:	BIBFORM114426
035-os BibID:	(cikkazonosító)663 (Scopus)85169116890 (WoS)001056247400001
Első szerző:	Sherif, Moustafa
Cím:	Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries : A Systematic Review and Meta-Analysis / Sherif Moustafa, Makame Khadija Ramadhan, Östlundh Linda, Paulo Marilia Silva, Nemmar Abderrahim, Ali Bassam R., Al-Rifai Rami H., Nagy Károly, Ádám Balázs
Dátum:	2023
ISSN:	2305-6304
Megjegyzések:	Exposure to pesticides in Arab countries is a significant public health concern due to extensive agricultural activity and pesticide use. This systematic review aimed to evaluate the genotoxic effects of agricultural pesticide exposure in the region, identify research gaps, and assess methodological limitations. Following the PRISMA guidelines, a comprehensive search yielded five relevant studies conducted in Egypt, Syria, and Jordan. Various genotoxicity assays were employed, revealing a higher level of DNA damage in exposed compared to non-exposed individuals. Farmers exposed to pesticides exhibited a significantly higher occurrence of chromosomal translocation (t(14;18)), micronuclei, and chromosomal aberrations. However, only two studies assessed cytotoxicity indirectly. The studies predominantly focused on male participants, with variations in sample size and pesticide types. The lack of detailed exposure data necessitates cautious interpretation. This review underscores the need for further research on the genotoxicity of occupational pesticide exposure in the Middle East. Future studies should adopt robust study designs, collect biological and environmental samples, conduct repeated sampling, analyze seasonal variations, and encompass diverse study sites associated with specific crop groups.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk pesticide occupational exposure agriculture Arab countries genotoxicity DNA damage
Megjelenés:	Toxics. - 11 : 8 (2023), p. 1-19. -
További szerzők:	Makame, Khadija Ramadhan Östlundh, Linda Paulo, Marilia Silva Nemmar, Abderrahim Ali, Bassam Al-Rifai, Rami H. Nagy Károly (1986-) (népegészségügyi felügyelő) Ádám Balázs (1973-) (megelőző orvostan és népegészségtan szakorvos)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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