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001-es BibID:BIBFORM103776
035-os BibID:(cikkazonosító)1000688 (WOS)000871611300001 (Scopus)85138178796
Első szerző:Farkas Zsuzsa
Cím:Probabilistic modeling and risk characterization of the chronic aflatoxin M1 exposure of Hungarian consumers / Zsuzsa Farkas, Kata Kerekes, Árpád Ambrus, Miklós Süth, Ferenc Peles, Tünde Pusztahelyi, István Pócsi, Attila Nagy, Péter Sipos, Gabriella Miklós, Anna Lőrincz10, Szilveszter Csorba, Ákos Bernard Jóźwiak
Dátum:2022
ISSN:1664-302X
Megjegyzések:Aflatoxin contamination can appear in various points of the food chain. If animals are fed with contaminated feed, AFB1 is transformed?among others?to aflatoxin M1 (AFM1) metabolite. AFM1 is less toxic than AFB1, but it is still genotoxic and carcinogenic and it is present in raw and processed milk and all kinds of milk products. In this article, the chronic exposure estimation and risk characterization of Hungarian consumers are presented, based on the AFM1 contamination of milk and dairy products, and calculated with a probabilistic method, the two-dimensional Monte-Carlo model. The calculations were performed using the R plugin (mc2d package) integrated into the KNIME (Konstanz Information Miner) software. The imulations were performed using data from the 2018?2020 food consumption survey. The AFM1 analytical data were derived from the Hungarian monitoring survey and 1,985 milk samples were analyzed within the framework of the joint project of the University of Debrecen and the National Food Chain Safety Office of Hungary (NÉBIH). Limited AFM1 concentrations were available for processed dairy products; therefore, a database of AFM1 processing factors for sour milk products and various cheeses was produced based on the latest literature data, and consumer exposure was calculated with the milk equivalent of the consumed quantities of these products. For risk characterization, the calculation of hazard index (HI), Margin of Exposure, and the hepatocellular carcinoma incidence were used. The results indicate that the group of toddlers that consume a large amount of milk and milk products are exposed to a certain level of health risk. The mean estimated daily intake of toddlers is in the range of 0.008?0.221ngkg?1 bw day?1; the 97.5th percentile exposure of toddlers is between 0.013ngkg?1 bw day?1 and 0.379ngkg?1 bw day?1, resulting in a HI above 1. According to our study, the exposure of older age groups does not pose an emergent health risk. Nevertheless, the presence of carcinogenic compounds should be kept to a minimum in the whole population.
Tárgyszavak:Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
AFM1
mycotoxin exposure assessment
probabilistic method
Megjelenés:Frontiers in Microbiology. - 13 (2022), p. 1-12. -
További szerzők:Kerekes Kata Ambrus Árpád Süth Miklós Peles Ferenc (1979-) (mikrobiológia, élelmiszer-mikrobiológia, minőségügy) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító) Pócsi István (1961-) (vegyész) Nagy Attila Sipos Péter (1975-) (agrármérnök) Miklós Gabriella Lőrincz Anna Csorba Szilveszter Jóźwiak Ákos
Pályázati támogatás:2018-1.2.1-NKP-2018-00002
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2.

001-es BibID:BIBFORM117489
Első szerző:Murvai Katalin
Cím:Microbial analysis of hungarian forage samples / Katalin Pappné Murvai, Hanna V. Rácz, Alexandra Imre, Enikő Horváth, Kadmiel Naliel Pereira, Ferenc Peles, Péter Sipos, Béla Béri, Tünde Pusztahelyi, István Pócsi, Valter Péter Pfiegler
Dátum:2023
ISSN:1217-8950 1588-2640
Tárgyszavak:Természettudományok Biológiai tudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Acta Microbiologica et Immunologica Hungarica. - 70 : Supplement-1 (2023), p. 76-77. -
További szerzők:Rácz Hanna Viktória (1994-) (biológus) Imre Alexandra (1992-) (biomérnök, biotechnológus) Horváth Enikő Kadmiel Naliel Pereira Peles Ferenc (1979-) (mikrobiológia, élelmiszer-mikrobiológia, minőségügy) Sipos Péter (1975-) (agrármérnök) Béri Béla (1951-) (agrármérnök) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító) Pócsi István (1961-) (vegyész) Pfliegler Valter Péter (1986-) (molekuláris biológus)
Pályázati támogatás:2018-1.2.1-NKP-2018-00002
Egyéb
FK 138910
Egyéb
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM091261
035-os BibID:(cikkazonosító)104
Első szerző:Peles Ferenc (mikrobiológia, élelmiszer-mikrobiológia, minőségügy)
Cím:Biological Control and Mitigation of Aflatoxin Contamination in Commodities / Ferenc Peles, Péter Sipos, Szilvia Kovács, Zoltán Győri, István Pócsi, Tünde Pusztahelyi
Dátum:2021
ISSN:2072-6651
Megjegyzések:Aflatoxins (AFs) are toxic secondary metabolites produced mostly by Aspergillus species. AF contamination entering the feed and food chain has been a crucial long-term issue for veterinarians, medicals, agroindustry experts, and researchers working in this field. Although different (physical, chemical, and biological) technologies have been developed, tested, and employed to mitigate the detrimental effects of mycotoxins, including AFs, universal methods are still not available to reduce AF levels in feed and food in the last decades. Possible biological control by bacteria, yeasts, and fungi, their excretes, the role of the ruminal degradation, pre-harvest biocontrol by competitive exclusion or biofungicides, and post-harvest technologies and practices based on biological agents currently used to alleviate the toxic effects of AFs are collected in this review. Pre-harvest biocontrol technologies can give us the greatest opportunity to reduce AF production on the spot. Together with post-harvest applications of bacteria or fungal cultures, these technologies can help us strictly reduce AF contamination without synthetic chemicals.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
biocontrol
aflatoxin
pre-harvest
post-harvest
non-aflatoxigenic
ruminal
Megjelenés:Toxins. - 13 : 2 (2021), p. 1-19. -
További szerzők:Sipos Péter (1975-) (agrármérnök) Kovács Szilvia (1982-) (biológus) Győri Zoltán (1948-) (vegyész) Pócsi István (1961-) (vegyész) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító)
Pályázati támogatás:2018-1.2.1-NKP-2018-00002
Egyéb
2020-4.1.1-TKP2020
Egyéb
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4.

001-es BibID:BIBFORM082608
035-os BibID:(cikkazonosító)2861 (WOS)000504275200001 (Scopus)85077285551
Első szerző:Peles Ferenc (mikrobiológia, élelmiszer-mikrobiológia, minőségügy)
Cím:Adverse Effects, Transformation and Channeling of Aflatoxins Into Food Raw Materials in Livestock / Ferenc Peles, Péter Sipos, Zoltán Győri, Walter P. Pfliegler, Federica Giacometti, Andrea Serraino, Giampiero Pagliuca, Teresa Gazzotti, István Pócsi
Dátum:2019
ISSN:1664-302X
Megjegyzések:Aflatoxins are wide-spread harmful carcinogenic secondary metabolites produced by Aspergillus species, which cause serious feed and food contaminations and affect farm animals deleteriously with acute or chronic manifestations of mycotoxicoses. On farm, both pre-harvest and post-harvest strategies are applied to minimize the risk of aflatoxin contaminations in feeds. The great economic losses attributable to mycotoxin contaminations have initiated a plethora of research projects to develop new, effective technologies to prevent the highly toxic effects of these secondary metabolites on domestic animals and also to block the carry-over of these mycotoxins to humans through the food chain. Among other areas, this review summarizes the latest findings on the effects of silage production technologies and silage microbiota on aflatoxins, and it also discusses the current applications of probiotic organisms and microbial products in feeding technologies. After ingesting contaminated foodstuffs, aflatoxins are metabolized and biotransformed differently in various animals depending on their inherent and acquired physiological properties. These mycotoxins may cause primary aflatoxicoses with versatile, species-specific adverse effects, which are also dependent on the susceptibility of individual animals within a species, and will be a function of the dose and duration of aflatoxin exposures. The transfer of these undesired compounds from contaminated feed into food of animal origin and the aflatoxin residues present in foods become an additional risk to human health, leading to secondary aflatoxicoses. Considering the biological transformation of aflatoxins in livestock, this review summarizes (i) the metabolism of aflatoxins in different animal species, (ii) the deleterious effects of the mycotoxins and their derivatives on the animals, and (iii) the major risks to animal health in terms of the symptoms and consequences of acute or chronic aflatoxicoses, animal welfare and productivity. Furthermore, we traced the transformation and channeling of Aspergillus-derived mycotoxins into food raw materials, particularly in the case of aflatoxin contaminated milk, which represents the major route of human exposure among animal-derived foods. The early and reliable detection of aflatoxins in feed, forage and primary commodities is an increasingly important issue and, therefore, the newly developed, easy-to-use qualitative and quantitative aflatoxin analytical methods are also summarized in the review.
Tárgyszavak:Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Frontiers in Microbiology. - 10 (2019), p. 1-26. -
További szerzők:Sipos Péter (1975-) (agrármérnök) Győri Zoltán (1948-) (vegyész) Pfliegler Valter Péter (1986-) (molekuláris biológus) Giacometti, Federica Serraino, Andrea Pagliuca, Giampiero Gazzotti, Teresa Pócsi István (1961-) (vegyész)
Pályázati támogatás:Debreceni Egyetem Biotechnológia tématerületi program
FIKP
2018-1.2.1-NKP-2018-00002
Egyéb
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5.

001-es BibID:BIBFORM092386
035-os BibID:(cikkazonosító)204
Első szerző:Sipos Péter (agrármérnök)
Cím:Physical and Chemical Methods for Reduction in Aflatoxin Content of Feed and Food / Sipos Péter, Peles Ferenc, Brassó Dóra Lili, Béri Béla, Pusztahelyi Tünde, Pócsi István, Győri Zoltán
Dátum:2021
ISSN:2072-6651
Megjegyzések:Aflatoxins (AFs) are among the most harmful fungal secondary metabolites imposing serious health risks on both household animals and humans. The more frequent occurrence of aflatoxins in the feed and food chain is clearly foreseeable as a consequence of the extreme weather conditions recorded most recently worldwide. Furthermore, production parameters, such as unadjusted variety use and improper cultural practices, can also increase the incidence of contamination. In current aflatoxin control measures, emphasis is put on prevention including a plethora of pre-harvest methods, introduced to control Aspergillus infestations and to avoid the deleterious effects of aflatoxins on public health. Nevertheless, the continuous evaluation and improvement of post-harvest methods to combat these hazardous secondary metabolites are also required. Already in-use and emerging physical methods, such as pulsed electric fields and other nonthermal treatments as well as interventions with chemical agents such as acids, enzymes, gases, and absorbents in animal husbandry have been demonstrated as effective in reducing mycotoxins in feed and food. Although most of them have no disadvantageous effect either on nutritional properties or food safety, further research is needed to ensure the expected efficacy. Nevertheless, we can envisage the rapid spread of these easy-to-use, cost-effective, and safe post-harvest tools during storage and food processing.
Tárgyszavak:Agrártudományok Élelmiszertudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
aflatoxin
mycotoxin
decontamination
absorption
Megjelenés:Toxins. - 13 : 3 (2021), p. 1-17. -
További szerzők:Peles Ferenc (1979-) (mikrobiológia, élelmiszer-mikrobiológia, minőségügy) Brassó Dóra Lili (1994-) (állattenyésztő mérnök) Béri Béla (1951-) (agrármérnök) Pusztahelyi Tünde (1969-) (biológus, angol-magyar szakfordító) Pócsi István (1961-) (vegyész) Győri Zoltán (1948-) (vegyész)
Pályázati támogatás:2018-1.2.1-NKP-2018-00002
Egyéb
TKP2020-IKA-04
Egyéb
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