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1.

001-es BibID:BIBFORM029049
Első szerző:Antal Miklós (orvos, anatómus)
Cím:Phagocytosis of myelin sheath fragments by dendrites / M. Antal, G. Székely
Dátum:1987
ISSN:0014-4819
Megjegyzések:In serial ultrathin sections of the frog spinal cord, profiles of dendritic appearance were identified that contained myelin fragment inclusions and received synaptic contacts. In a number of cases it could be established that the inclusions were derived from adjacent myelin sheaths. It is suggested that the phenomenon may refer to a turnover of the myelin sheath in which the detached myelin fragments are eliminated by dendrites.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Experimental Brain Research. - 66 : 3 (1987), p. 517-521. -
További szerzők:Székely György (1926-2017) (neurobiológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM028819
Első szerző:Balla András
Cím:Immunohistochemical localisation of two phosphatidylinositol 4-kinase isoforms, PI4K230 and PI4K92, in the central nervous system of rats / Balla A., Vereb Gy., Gülkan H., Gehrmann T., Gergely P., Heilmeyer L. M. G. Jr., Antal M.
Dátum:2000
ISSN:0014-4819
Megjegyzések:The distribution and cellular localisation of the phosphatidylinositol 4-kinase isoforms, PI4K230 and PI4K92, that are believed to play important roles in the intracellular signalling mechanisms were studied in the rat brain (cortex, cerebellum, hippocampus and spinal cord) using immunocytochemistry with light and electron microscopy. PI4K230 was detected with a specific antibody purified by affinity chromatography from the egg yolk of chicken immunised with a 33-kDa fragment of bovine PI4K230, comprising amino acids 873-1175 of the native protein. PI4K92 was immunostained with a commercially available antibody raised in rabbit against amino acid residues 410-537 of human PI4K92. At the light microscopic level, the immunostaining of PI4K230 and PI4K92 showed a very similar distribution throughout the neurons and appeared as dense punctate labelling in the cytoplasm of perikarya and stem dendrites of various neurons. In addition to neurons, a strongly stained cell population was observed in the molecular layer of the cerebellar cortex that resembled Bergmann glia cells. Electron microscopy of neurons in the ventral horn of the spinal cord showed dense granular immunoprecipitates for both PI4K230 and PI4K92, mostly associated with the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. In addition, immunostaining of PI4K92 was also frequently found on the outer surface of cisterns and vesicles of Golgi complexes, whereas PI4K230 immunoreactivity was colocalised with some multivesicular bodies. Neither nuclear localisation nor a regular attachment to the cell membrane of these enzymes were observed. Our findings indicate that PI4K230 and PI4K92 are not involved directly in the ligand-stimulated turnover of phosphoinositides at the plasma membrane of neurons. However, they may provide regulatory phosphoinositides for intracellular vesicular traffic being associated with various organelles.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Experimental Brain Research. - 134 : 3 (2000), p. 279-288. -
További szerzők:Vereb György (1938-) (biokémikus, sejtbiológus) Gülkan, Hülya Gehrmann, Thor Gergely Pál (1947-) (biokémikus) Heilmeyer, Ludwig M. G. Jr. Antal Miklós (1951-) (orvos, anatómus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM028823
Első szerző:Odeh, Francis
Cím:Heterogeneous synaptic inputs from the ventrolateral periaqueductal gray matter to neurons responding to somatosensory stimuli in the rostral ventromedial medulla of rats / Odeh F., Antal M., Zagon A.
Dátum:2003
Megjegyzések:The ventrolateral cell column of the midbrain periaqueductal gray matter (vl-PAG) plays a major role in the attenuation of pain behaviour. It is established that this effect is exerted via modulation of neuronal activities in the rostral ventromedial medulla (RVM). Until recently it has been generally accepted that the vl-PAG exerts its modulatory effects upon RVM neurons through a direct monosynaptic pathway. However, recent data suggest that an additional indirect, di- or polysynaptic pathway may also exist. Using in vivo intracellular recordings we tested this hypothesis, by studying synaptic responses of somatosensory receptive RVM neurons evoked by electric stimulation of the vl-PAG in rats. RVM neurons were regarded as somatosensory receptive if they responded to electrical stimulation of the sciatic nerve. Most of the recorded RVM cells were excited by vl-PAG stimulation. Some of them responded with a short onset latency (3.6+/-0.9 ms) corresponding to monosynaptic excitation. All of these neurons were also excited by sciatic nerve stimulation at nociceptive intensities. In contrast to this, another proportion of the recorded RVM neurons responded with a four times longer (14.8+/-3 ms) onset latency to the vl-PAG stimulation, corresponding to polysynaptic modulation. All of these neurons were inhibited by sciatic nerve stimulation. The findings show that RVM neurons receive heterogeneous monosynaptic and polysynaptic inputs from the vl-PAG. The results also suggest that the monosynaptic and polysynaptic pathways modulate the activity of functionally distinct groups of RVM neurons.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Brain Research. - 959 : 2 (2003), p. 287-294. -
További szerzők:Antal Miklós (1951-) (orvos, anatómus) Zagon Anikó
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM036986
035-os BibID:PMID:22732529
Első szerző:Petkó Mihály (orvos, neurobiológus)
Cím:Propriospinal pathways in the dorsal horn (laminae I-IV) of the rat lumbar spinal cord / Mihály Petkó, Miklós Antal
Dátum:2012
ISSN:0361-9230
Megjegyzések:The spinal dorsal horn is regarded as a unit that executes the function of sensory information processing without any significant communication with other regions of the spinal gray matter. Within the spinal dorsal horn, however, the different rostro-caudal and medio-lateral subdivisions intensively communicate with each other through propriospinal pathways. This review gives an overview about these propriospinal systems, and emphasizes that the medial and lateral parts of the spinal dorsal horn show the following distinct features in their propriospinal interconnectivities: (a) A 100-300m long section of the medial aspects of laminae I-IV projects to and receives afferent fibers from a three segment long compartment of the spinal dorsal gray matter, whereas the same length of the lateral aspects of laminae I-IV projects to and receives afferent fibers from the entire rostro-caudal extent of the lumbar spinal cord. (b) The medial aspects of laminae I-IV project extensively to the lateral areas of the dorsal horn. In contrast to this, the lateral areas of laminae I-IV, with the exception of a few fibers at the segmental level, do not project back to the medial territories. (c) There is a substantial direct commissural connection between the lateral aspects of laminae I-IV on the two sides of the lumbar spinal cord. The medial part of laminae I-IV, however, establishes only a minor commissural propriospinal connection with the gray matter on the opposite side.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Brain Research Bulletin. - 89 : 1-2 (2012), p. 41-49. -
További szerzők:Antal Miklós (1951-) (orvos, anatómus)
Internet cím:Szerző által megadott URL
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Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM029083
Első szerző:Polgár Erika
Cím:The colocalization of parvalbumin and calbindin-D28k with GABA in the subnucleus caudalis of the rat spinal trigeminal nucleus / E. Polgár, M. Antal
Dátum:1995
ISSN:0014-4819
Megjegyzések:The colocalization of two calcium-binding proteins, parvalbumin (PV) and calbindin-D28k (CaB), which have been reported to be markers of specific subpopulations of neurons in the central nervous system, with the inhibitory amino acid neurotransmitter gamma-amino-butyric acid (GABA) was investigated in neurons of laminae I-IV of the subnucleus caudalis of the rat spinal trigeminal nucleus by using post-embedding immunocytochemical methods. Cells immunoreactive for PV, CaB, and GABA were found in all four laminae of the subnucleus caudalis. A substantial proportion of PV-immunoreactive perikarya were also stained for GABA in laminae II and III (44.8% and 39.8%, respectively). However, the majority of PV-containing neurons in laminae I and IV (100% and 86%, respectively), as well as CaB-immunoreactive cells in all four laminae (98.4%), were GABA-negative. These results show that, in contrast to higher brain centers, PV-, CaB-, and GABA-immunoreactive perikarya represent significantly different populations of neurons in the subnucleus caudalis of the rat. In the light of the present findings, the differences in the neurochemical properties of the subnucleus caudalis of the spinal trigeminal nucleus and the spinal dorsal horn are also discussed.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Experimental Brain Research. - 103 : 3 (1995), p. 402-408. -
További szerzők:Antal Miklós (1951-) (orvos, anatómus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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6.

001-es BibID:BIBFORM028806
Első szerző:Székely György (neurobiológus)
Cím:The termination of cutaneous nerves in the dorsal horn of the spinal cord in normal and in skin-rotated frogs / Székely G., Matesz K., Baker R. E., Antal M.
Dátum:1982
Megjegyzések:Following transganglionic transport of cobaltic lysine applied to the cut end of cutaneous nerves, the central terminal arbours were filled to such an extent that it was possible to visualize the dermatomal projection upon the dorsal horn in unoperated and in skin-rotated frogs. Sensory nerves of the trunk skin terminate in an oval-shaped area which probably corresponds to laminae 1-3 (or 1-4) in the mammalian spinal cord. One type of terminating collateral had a restricted terminal field either in the medial, or in the lateral, part of the oval-shaped area. Another type ended with a large terminal arbour covering almost the total extent of the oval shaped area. These terminal arbours were found for both the dorsal and the ventral cutaneous nerves. Dorsal cutaneous nerves projected preferentially to the lateral part, while ventral cutaneous nerves projected to the medial part, but both nerves sent a significant contingent of collaterals to the whole extent of the oval-shaped area. A rearrangement of the central projection patterns of the dorsal cutaneous nerves, consistently mediating misdirected responses, was not observed in skin-rotated frogs. Collaterals of trunk skin nerves terminated exclusively in the thoracic segments; they did not enter the limb-innervating (brachial and lumbosacral) segments of the spinal cord. The results corroborate the crossed pattern of sensory input in the dermatomal projection. The large, extensively overlapping, areas of termination of individual skin nerves suggest that wiping responses mediated by these nerves should be regarded as complex behaviour released from a preprogrammed centre rather than a reflex arc in which the presence specificity would be determined by wiring specificity.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Experimental Brain Research. - 45 : 1-2 (1982), p. 19-28. -
További szerzők:Matesz Klára (1949-) (anatómus, neurobiológus) Baker, R. E. Antal Miklós (1951-) (orvos, anatómus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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7.

001-es BibID:BIBFORM001430
Első szerző:Wéber Ildikó (biológus, neurobiológus)
Cím:Neurotransmitter systems of commissural interneurons int he lumbar spinal cord of neonatal rats / Wéber I., Veress G., Szűcs P., Antal M., Birinyi A.
Dátum:2007
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Brain Research. - 1178 (2007), p. 65-72. -
További szerzők:Veress Gábor (1971-) (neurobiológus) Szűcs Péter (1974-) (kutatóorvos) Antal Miklós (1951-) (orvos, anatómus) Birinyi András (1960-) (anatómus, neurobiológus)
Pályázati támogatás:046121
OTKA
032075
OTKA
T032075
OTKA
Internet cím:elektronikus változat
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8.

001-es BibID:BIBFORM001419
Első szerző:Wéber Ildikó (biológus, neurobiológus)
Cím:Projections of primary afferent fibers to last-order premotor interneurons in the lumbar spinal cord of rats / Wéber I., Puskár Z., Kozák N., Antal M.
Dátum:2007
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Brain Research Bulletin. - 71 : 4 (2007), p. 337-343. -
További szerzők:Puskár Zita Kozák Norbert (1978-) (neurológus) Antal Miklós (1951-) (orvos, anatómus)
Pályázati támogatás:046121
OTKA
Internet cím:elektronikus változat
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