Találati lista | Tudóstér

001-es BibID:	BIBFORM015605
035-os BibID:	15721147
Első szerző:	Felszeghy Szabolcs Béla (fogorvos, anatómus, kötőszövetbiológus)
Cím:	The expression pattern of hyaluronan synthase during human tooth development / Felszeghy S., Meszar Z., Prehm P., Modis L.,
Dátum:	2005
ISSN:	0003-9969 (Linking)
Megjegyzések:	In previous studies, hyaluronan (HA) and its major cell surface receptor CD44have been suggested to play an important role during tooth development. HAsynthases (HASs) are the enzymes that polymerize hyaluronan. Data on theexpression pattern of HASs during tooth development is lacking and the aim of thepresent study was to investigate the localisation of HAS by immunohistochemistryin human tooth germs from different developmental stages. The distributionpattern of HAS in the various tissues of the "bell stage" tooth primordiacorresponded to that of hyaluronan in most locations: positive HASepithelium. On the stellate reticulum cells, moderate HAS signal was observed,similar to the layers of the oral epithelium, where faint HAS immunoreactivitywas detected. At the early phase of dental hard tissues mineralization, strongHAS immunoreactivity was detected in the odontoblasts and their processes, aswell as in the secretory ameloblasts and their apical processes and also, thepulpal mesenchymal cells. The HAS signals observed in odontoblasts andameloblasts gradually decreased with age. Our results demonstrate that hyaluronansynthesised locally by different dental cells and these results provideadditional indirect support to the suggestion that HA may contribute both to theregulation of tooth morphogenesis and dental hard tissue formation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban 9004-61-9 (Hyaluronic Acid) EC 2.4.1.17 (Glucuronosyltransferase) EC 2.4.1.212 (hyaluronan synthase) Ameloblasts/chemistry/enzymology Female Glucuronosyltransferase/analysis Humans Hyaluronic Acid/analysis Immunohistochemistry/methods Mouth Mucosa/chemistry/embryology Odontoblasts/chemistry/enzymology Odontogenesis/physiology Pregnancy Pregnancy Trimester, Second Pregnancy Trimester, Third Tooth Germ/*chemistry/enzymology egyetemen (Magyarországon) készült közlemény
Megjelenés:	Archives of oral biology. - 50 : 2 (2005), p. 175-179. -
További szerzők:	Mészár Zoltán Mihály (1977-) (agrármérnök) Prehm, P. Módis László (1939-) (anatómus, kötőszövetbiológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
Borító:
Saját polcon: