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001-es BibID:	BIBFORM003596
Első szerző:	Irinyi Beatrix (bőrgyógyász, allergológus)
Cím:	Clinical and laboratory examinations in the subgroups of chronic urticaria / Irinyi B., Széles Gy., Gyimesi E., Tumpek J., Herédi E., Dimitrios G., Ádány R., Hunyadi J., Szegedi A.
Dátum:	2007
Megjegyzések:	The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35 %, autoimmune urticaria (AIU) at 25 % and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. Methods: Differences in clinical and laboratory parameters among AIU, PU and CIU groups were examined. AIU was diagnosed if basophil CD63 assay was positive. Demographic data, severity of symptoms, and association with allergic and autoimmune diseases were analysed by the aid of an internationally accepted questionnaire a questionnarie. Immunoassays were carried out and the effectiveness of therapy was also investigated. Results: Female dominance in the AIU group was prominent. Concerning the urticaria score, there were significant differences between the AIU and PU patients (p=0.015) and between AIU and CIU cases (p=0.013). Between the CIU and PU patients, we found an insignificant difference in the urticaria score (p=0.78). AIU was more frequently associated with autoimmune diseases in the personal (p<0.001), and with other types of urticaria in the family history (p<0.001). Also anti-thyroid antibodies were more frequently detected in the AIU group. Antihistamine therapy was less effective in the AIU group (12.8%) than in the PU (70.3%) and CIU groups (68.6 %), but there were no significant differences between the CIU and PU groups regarding the effectiveness of antihistamine therapy. Conclusion: The autoimmune subgroup represents the most severe form of chronic urticaria. On the other hand between the CIU and PU groups there were no significant differences in urticaria scores as well as in response to antihistamine therapy. Key words: antihistamine therapy, autoimmune urticaria, physical urticaria, chronic idiopathic urticaria
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban chronic urticaria
Megjelenés:	International Archives of Allergy and Immunology 144 : 3 (2007), p. 217-225. -
További szerzők:	Széles György (1969-) (epidemiológus) Gyimesi Edit (1957-) (klinikai biokémikus, vegyész) Tumpek Judit (1944-) (orvosi laboratóriumi szakorvos) Herédi Emese (1979-) (bőrgyógyász) Dimitrios, Georgitsis Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) Hunyadi János (1943-) (bőrgyógyász, kozmetológus, allergológus) Szegedi Andrea (1964-) (bőrgyógyász)
Internet cím:	elektronikus változat DOI
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001-es BibID:	BIBFORM025043
Első szerző:	Nagy Georgina (orvosbiológus)
Cím:	Association between Serum IL-16 Levels and the Degree of Sensitization in Patients with Atopic Dermatitis / Nagy Georgina, Gáspár Krisztián, Irinyi Beatrix, Gál Mónika, Tumpek Judit, Gyimesi Edit, Sipka Sándor, Remenyik Éva, Szodoray Péter, Szegedi Andrea
Dátum:	2011
ISSN:	1018-2438
Megjegyzések:	Background: Interleukin (IL)-16 has been characterized as animmunomodulatory cytokine. Besides its chemotactic properties,IL-16 amplifies inflammatory processes and possessesimmunoregulatory functions. Our aim was to investigate theassociation between serum IL-16 levels and the degree of allergicsensitization in patients with atopic dermatitis (AD).Methods: The serum level of IL-16 was measured by immunoenzymaticassays. Eosinophil cell count, serum total andspecific IgE levels were assessed; prick tests were also carriedout. Based on specific IgE levels and prick tests, AD patientswere divided into sensitized and nonsensitized subgroups,and correlations among serum IL-16, total IgE levels and eosinophilcell counts were measured in the total patient groupand in subgroups. Results: In the total patient group, significantlyhigher levels of IL-16 were found in the sera of patientswith AD, compared to healthy individuals and patientswith psoriasis. A significant correlation was detected betweenserum levels of IL-16 and total IgE, total IgE andeosinophil counts, but not between IL-16 and eosinophils.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Interleukin-16 Atopic dermatitis Cytokines
Megjelenés:	International Archives Of Allergy And Immunology 156 : 1 (2011), p. 69-74. -
További szerzők:	Gáspár Krisztián (1974-) (bőrgyógyász) Irinyi Beatrix (1972-) (bőrgyógyász, allergológus) Gál Mónika Tumpek Judit (1944-) (orvosi laboratóriumi szakorvos) Gyimesi Edit (1957-) (klinikai biokémikus, vegyész) Sipka Sándor (1945-) (laboratóriumi szakorvos) Remenyik Éva (1956-) (bőrgyógyász) Szodoray Péter (1973-) (belgyógyász, orvos) Szegedi Andrea (1964-) (bőrgyógyász)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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