CCL

Összesen 2 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM053829
Első szerző:Gustafsson, Jenny S.
Cím:Ultrastructural organization of lamprey reticulospinal synapses in three dimensions / Jenny S. Gustafsson, András Birinyi, John Crum, Mark Ellisman, Lennart Brodin, Oleg Shupliakov
Dátum:2002
ISSN:0021-9967
Megjegyzések:The giant reticulospinal synapse in lamprey provides a unique model to study synaptic vesicle traffic. The axon permits microinjections, and the active zones are often separated from each other, which makes it possible to track vesicle cycling at individual release sites. However, the proportion of reticulospinal synapses with individual active zones ("simple synapses") is unknown and a quantitative description of their organization is lacking. Here, we report such data obtained by serial section analysis, intermediate-voltage electron microscopy, and electron tomography. The simple synapse was the most common type (78%). It consisted of one active zone contacting one dendritic process. The remaining synapses were "complex," mostly containing one vesicle cluster and two to three active zones synapsing with distinct dendritic shafts. Occasional axosomatic synapses with multiple active zones forming synapses with the same cell were also observed. The vast majority of active zones in all synapse types contained both chemical and electrotonic synaptic specializations. Quantitative analysis of simple synapses showed that the majority had active zones with a diameter of 0.8-1.8 microm. The number of synaptic vesicles and the height of the vesicle cluster in middle sections of serially cut synapses correlated with the active zone length within, but not above, this size range. Electron tomography of simple synapses revealed small filaments between the clustered synaptic vesicles. A single vesicle could be in contact with up to 12 filaments. Another type of filament, also associated with synaptic vesicles, emerged from dense projections. Up to six filaments could be traced from one dense projection.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Comparative Neurology. - 450 : 2 (2002), p. 167-182. -
További szerzők:Birinyi András (1960-) (anatómus, neurobiológus) Crum, John Ellisman, Mark Brodin, Lennart Shupliakov, Oleg
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM053911
Első szerző:Shayan, Alexander J.
Cím:Neurotransmitter levels and synaptic strength at the drosophila larval neuromuscular junction are not altered by mutation in the sluggish-a gene, which encodes proline oxidase and affects adult locomotion / Alexander J. Shayan, Lennart Brodin, Ole P. Ottersen, Andras Birinyi, Caitlin E. Hill, C. K. Govind, Harold L. Atwood, Oleg Shupliakov
Dátum:2000
ISSN:0167-7063
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Neurogenetics. - 14 : 3 (2000), p. 165-192. -
További szerzők:Brodin, Lennart Ottersen, Ole P. Birinyi András (1960-) (anatómus, neurobiológus) Hill, Caitlin E. Govind, C. K. Atwood, Harold L. Shupliakov, Oleg
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1