CCL

Összesen 1 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM061115
Első szerző:Markram, Henry
Cím:Reconstruction and Simulation of Neocortical Microcircuitry / Henry Markram, Eilif Muller, Srikanth Ramaswamy, Michael W. Reimann, Marwan Abdellah, Carlos Aguado Sanchez, Anastasia Ailamaki, Lidia Alonso-Nanclares, Nicolas Antille, Selim Arsever, Guy Antoine Atenekeng Kahou, Thomas K. Berger, Ahmet Bilgili, Nenad Buncic, Athanassia Chalimourda, Giuseppe Chindemi, Jean-Denis Courcol, Fabien Delalondre, Vincent Delattre, Shaul Druckmann, Raphael Dumusc, James Dynes, Stefan Eilemann, Eyal Gal, Michael Emiel Gevaert, Jean-Pierre Ghobril, Albert Gidon, Joe W. Graham, Anirudh Gupta, Valentin Haenel, Etay Hay, Thomas Heinis, Juan B. Hernando, Michael Hines, Lida Kanari, Daniel Keller, John Kenyon, Georges Khazen, Yihwa Kim, James G. King, Zoltan Kisvarday, Pramod Kumbhar, Sébastien Lasserre, Jean-Vincent Le Bé, Bruno R.C. Magalhǎes, Angel Merchán-Pérez, Julie Meystre, Benjamin Roy Morrice, Jeffrey Muller, Alberto Muňoz-Céspedes, Shruti Muralidhar, Keerthan Muthurasa, Daniel Nachbaur, Taylor H. Newton, Max Nolte, Aleksandr Ovcharenko, Juan Palacios, Luis Pastor, Rodrigo Perin, Rajnish Ranjan, Imad Riachi, José-Rodrigo Rodríguez, Juan Luis Riquelme, Christian Rössert, Konstantinos Sfyrakis, Ying Shi, Julian C. Shillcock, Gilad Silberberg, Ricardo Silva, Farhan Tauheed, Martin Telefont, Maria Toledo-Rodriguez, Thomas Tränkler, Werner Van Geit, Jafet Villafranca Díaz, Richard Walker, Yun Wang, Stefano M. Zaninetta, Javier DeFelipe, Sean L. Hill, Idan Segev, Felix Schürmann
Dátum:2015
ISSN:0092-8674
Megjegyzések:We present a first-draft digital reconstruction of themicrocircuitry of somatosensory cortex of juvenilerat. The reconstruction uses cellular and synapticorganizing principles to algorithmically reconstructdetailed anatomy and physiology from sparse experimentaldata. An objective anatomical method definesa neocortical volume of 0.29 ? 0.01 mm3 containing 31,000 neurons, and patch-clamp studies identify55 layer-specific morphological and 207 morphoelectricalneuron subtypes. When digitally reconstructedneurons are positioned in the volume andsynapse formation is restricted to biological boutondensities and numbers of synapses per connection,their overlapping arbors form 8 million connectionswith 37 million synapses. Simulations reproducean array of in vitro and in vivo experiments withoutparameter tuning. Additionally, we find a spectrumof network stateswitha sharp transition fromsynchronousto asynchronous activity, modulated by physiologicalmechanisms. The spectrumof network states,dynamically reconfigured around this transition, supportsdiverse information processing strategies.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Cell. - 163 : 2 (2015), p. 456-492. -
További szerzők:Muller, Eilif Ramaswamy, Srikanth Reimann, Michael W. Abdellah, Marwan Sanchez, Carlos Aguado Ailamaki, Anastasia Alonso-Nanclares, Lidia Antille, Nicolas Arsever, Selim Atenekeng Kahou, Guy Antoine Berger, Thomas K. Bilgili, Ahmet Buncic, Nenad Chalimourda, Athanassia Chindemi, Giuseppe Courcol, Jean-Denis Delalondre, Fabien Delattre, Vincent Druckmann, Shaul Dumusc, Raphael Dynes, James Eilemann, Stefan Gal, Eyal Gevaert, Michael Emiel Ghobril, Jean-Pierre Gidon, Albert Graham, Joe W. Gupta, Anirudh Haenel, Valentin Hay, Etay Heinis, Thomas Hernando, Juan B. Hines, Michael Kanari, Lida Keller, Daniel Kenyon, John Khazen, Georges Kim, Yihwa King, James G. Kisvárday Zoltán (1957-) (biológus, neurobiológus) Kumbhar, Pramod Lasserre, Sébastien Le Bé, Jean-Vincent Magalhǎes, Bruno R.C. Merchán-Pérez, Angel Meystre, Julie Morrice, Benjamin Roy Muller, Jeffrey Muňoz-Céspedes, Alberto Muralidhar, Shruti Muthurasa, Keerthan Nachbaur, Daniel Newton, Taylor H. Nolte, Max Ovcharenko, Aleksandr Palacios, Juan Pastor, Luis Perin, Rodrigo Ranjan, Rajnish Riachi, Imad Rodríguez, José-Rodrigo Riquelme, Juan Luis Rössert, Christian Sfyrakis, Konstantinos Shi, Ying Shillcock, Julian C. Silberberg, Gilad Silva, Ricardo Tauheed, Farhan Telefont, Martin Toledo-Rodriguez, Maria Tränkler, Thomas Van Geit, Werner Díaz, Jafet Villafranca Walker, Richard Wang, Yun Zaninetta, Stefano M. DeFelipe, Javier Hill, Sean Segev, Idan Schürmann, Felix
Internet cím:DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1