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1.

001-es BibID:BIBFORM045827
Első szerző:Barabás György (sejtbiológus, molekuláris genetikus)
Cím:Hormone-like factors influencing differentiation of Streptomyces cultures / Gy. Barabas, A. Penyige, T. Hirano
Dátum:1994
ISSN:0168-6445
Megjegyzések:Actinomycetes produce and export small autoregulatory molecules, which act like prokaryotic hormones. They can promote or induce sporulation, aerial hyphae formation and antibiotic production. The mode of action of the gamma-lactone AF is partly elucidated, those of the others are not known. These autoregulators (hormones) are effective if exogenously added to culture in proper time of the life cycle and in very low concentration. Since they influence the length of idiophase where secondary metabolites are produced their study may have pratical importance.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
A-FACTOR
A-FACTOR-BINDING PROTEIN;
AUTOREGULATOR
GTP-ASE ACTIVITY
STREPTOMYCES GRISEUS
Megjelenés:Fems Microbiology Reviews. - 14 : 1 (1994), p. 75-82. -
További szerzők:Penyige András (1954-) (molekuláris genetikus) Hirano, Tadashi
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DOI
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2.

001-es BibID:BIBFORM004678
035-os BibID:(scopus)0035153667 (wos)000171533400007
Első szerző:Barabás György (sejtbiológus, molekuláris genetikus)
Cím:N-Alkane uptake and utilisation by Streptomyces strains / Barabas, G., Vargha, G., Szabo, I. M., Penyige, A., Damjanovich, S., Szollosi, J., Matko, J., Hirano, T., Matyus, A., Szabo, I.
Dátum:2001
Megjegyzések:Streptomyces strains isolated from the Kuwait Burgan oil field were defined as S. griseoflavus, S. parvus, and S. plicatus utilised n-hexadecane, n-octadecane (purified fractions of mineral oil), kerosene, and crude oil as sole carbon and energy sources. The strains were incubated with n-alkanes and increase of the fatty acid content with chain length equivalent to the employed n-alkanes was observed. Signal transducing GTP-binding proteins (GBPs) play an important role in n-alkane uptake in streptomycetes. Specific activators of GBPs increased the uptake of hydrocarbons. Using the hydrophobic fluorescent dye diphenylhexatrien (DPH) as a probe, it was found that the microviscosity of the hydrophobic inner region of the cellular membrane is significantly lower in hydrocarbon utilisers than in non-utilisers. This difference probably reflects differences in the fatty acid composition of the strains. When cultures were grown in n-alkane containing media, electron microscopy revealed that the hydrocarbon utilisers showed less-electron dense areas as inclusions in the cytoplasm. Soil samples inoculated with Streptomyces strains eliminated hydrocarbons much faster than those not containing these strains, serving as control. When inorganic medium was supplied with n-hexadecane-1-14C as sole carbon and energy source, radioactive CO2 was detected. Since streptomycetes have not been used until now for oil elimination, though they are known as abundant soil bacteria tolerating extreme conditions, their possible use for bioremediation of hydrocarbon contaminated soils is discussed.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Alkanes
analogs and derivatives
analysis
Biodegradation
Cell Membrane
Cell Membrane Permeability
chemistry
Cytoplasm
Diphenylhexatriene
Dyes
Fatty Acids
Fluorescent Dyes
genetics
GTP-Binding Proteins
Human
Hungary
Hydrocarbons
metabolism
Microscopy
physiology
Streptomyces
Support,Non-U.S.Gov't
ultrastructure
Megjelenés:Antonie Van Leeuwenhoek. - 79 : 3-4 (2001), p. 269-276. -
További szerzők:Vargha György (1951-) (orvos) Szabó István M. Penyige András (1954-) (molekuláris genetikus) Damjanovich Sándor (1936-2017) (biofizikus) Szöllősi János (1953-) (biofizikus) Matkó János (1952-) (biológus) Hirano, Tadashi Mátyus Anita Szabó István
Internet cím:elektronikus változat
DOI
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3.

001-es BibID:BIBFORM004636
035-os BibID:(scopus)0031763323 (wos)000077220800013
Első szerző:Radwan, S. S.
Cím:Hydrocarbon uptake by streptomyces / Radwan, S. S., Barabas, G., Sorkhoh, N. A., Damjanovich, S., Szabo, I., Szollosi, J., Matko, J., Penyige, A., Hirano, T., Szabo, I. M.
Dátum:1998
ISSN:378-1097
Megjegyzések:Oligocarbophilic Streptomyces strains capable of hydrocarbon uptake and utilization were isolated from the polluted desert of Kuwait and used in this study. Transmission electron-microscopy of hyphae revealed that they become enriched with large less electron dense areas in the cytoplasm, when biomass samples were incubated with alkanes. The Streptomyces isolate could utilize n-hexadecane as sole carbon and energy source and their fatty acid content showed an increase in the fatty acids with chain length equivalent to those of the alkane substrates. Fluorescence measurements of diphenylhexatriene dissolved in the representative alkane, n-hexadecane, showed that the kinetics of hydrocarbon uptake are quite different in hydrocarbon-utilizer compared with non-utilizer Streptomyces strain. Microviscosity of the cellular membrane of the utilizer strain was also different from that of the non-utilizer control strain Streptomyces griseus after incubation in the presence of n-hexadecane. Very likely the hydrocarbon utilizer transported these compounds more efficiently across their membranes and accumulated them as inclusions in the cytoplasm
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Alkanes
Biomass
Cell Membrane
Cytoplasm
Desert Climate
Diphenylhexatriene
Environmental Microbiology
Environmental Pollution
Extraction and Processing Industry
Fatty Acids
Fluorescence
isolation and purification
Kinetics
Kuwait
metabolism
Petroleum
Streptomyces
Support
ultrastructure
Non-U.S.Gov't
Megjelenés:FEMS Microbiology Letters. - 169 : 1 (1998), p. 87-94. -
További szerzők:Barabás György (1933-) (sejtbiológus, molekuláris genetikus) Sorkhoh, N. A. Damjanovich Sándor (1936-2017) (biofizikus) Szabó I. Szöllősi János (1953-) (biofizikus) Matkó János (1952-) (biológus) Penyige András (1954-) (molekuláris genetikus) Hirano, Tadashi Szabó I. M.
Internet cím:elektronikus változat
DOI
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