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001-es BibID:	BIBFORM116137
035-os BibID:	(cikkazonosító)1226 (WoS)001152827800001 (Scopus)85178271139
Első szerző:	Gangaram, Serisha
Cím:	Antioxidant and Cytotoxic Activities of Leaf and Stem Extracts of Barleria albostellata C.B. Clarke / Gangaram, Serisha; Naidoo, Yougasphree; Dewir, Yaser Hassan; Singh, Moganavelli; Daniels, Aliscia Nicole; Magyar-Tábori, Katalin; Mendler-Drienyovszki, Nóra
Dátum:	2023
ISSN:	2311-7524
Megjegyzések:	Barleria albostellata C.B. Clarke (Acanthaceae) is a plant native to South Africa and relatively few studies have been performed on it. Species in this genus are known for their ethnopharmacological and phyto-medicinal values. In this study, the total flavonoid and phenolic contents and the antioxidant and cytotoxic activities of hexane, chloroform, and methanol extracts were evaluated at five different concentrations (15, 30, 60, 120, and 240 mu g/mL). The antioxidant activity of the extracts of B. albostellata was assessed in vitro using the 2,2 '-diphenyl-1-picrylhydrazyl (DPPH) scavenging and ferric reducing antioxidant power (FRAP) assays, while the phenolic content was determined using a Folin-Ciocalteu assay. The extracts' cytotoxicity was established using a 3-[(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] (MTT) assay in human embryonic kidney (HEK293), cervical cancer (HeLa), and breast adenocarcinoma (MCF-7) cell lines. Methanolic leaf extracts had the highest total flavonoid content (42.39 +/- 1.14 mg GAE/g DW) compared to other solvents. Additionally, the total phenolic content was the greatest in the methanol leaf extract (6.05 +/- 0.09 GAE/g DW), followed by the methanol stem extracts (2.93 +/- 0.73 GAE/g DW). The methanolic leaf and stem extract concentrations needed for 50% inhibition (DPPH) were 16.95 mu g/mL and 14.27 mu g/mL, respectively, whereas for FRAP, the reducing powers of all extracts were considerably lower than the ascorbic acid standard. The IC50 values of extracts tested in the three cell lines were >63 mu g/mL. According to the findings of our study, the leaves and stems of B. albostellata are rich in several bioactive compounds that may be a possible source of natural antioxidants and may have the potential to treat certain diseases. The extraction of the bioactive compounds from the leaves and stems of B. albostellata using bioassay-guided fractionation and the assessment of their safety will be essential for further investigations into this species in the search of potential novel therapeutic drug leads. To the best of our knowledge, this is the first report of the cytotoxic activities of leaf and stem extracts of Barleria albostellata.
Tárgyszavak:	Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Horticulturae. - 9 : 11 (2023), p. 1-18. -
További szerzők:	Naidoo, Yougasphree Dewir, Yaser Hassan Singh, Moganavelli Daniels, Aliscia Nicole Magyarné Tábori Katalin (1965-) (kertészmérnök) Mendlerné Drienyovszki Nóra (1977-) (agrármérnök)
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001-es BibID:	BIBFORM102634
035-os BibID:	(cikkazonosító)591 (WoS)000833676900001 (Scopus)85133533530
Első szerző:	Hanász Alexandra (környezetgazdálkodási agrármérnök)
Cím:	Responses of Potato (Solanum tuberosum L.) Breeding Lines to Osmotic Stress Induced in In Vitro Shoot Culture / Hanász Alexandra, Dobránszki Judit, Mendler-Drienyovszki Nóra, Zsombik László, Magyar-Tábori Katalin
Dátum:	2022
ISSN:	2311-7524
Megjegyzések:	In vitro experiments were conducted to study the responses of potato (Solanum tuberosum L.) genotypes to osmotic stress. In vitro shoot cultures of 27 breeding lines and their drought-tolerant parents (referent lines: C103 and C107) were tested under osmotic stress induced by addition of PEG 6000 (Mw = 6000; 5.0, 7.5, 10.0%, w/v), D-mannitol (0.1, 0.2, 0.3 M) and PEG 600 (Mw = 600; 2.5, 5.0, 7.5%, w/v) to the Murashige-Skoog medium. Stress index (SI) was calculated from shoot length (SL) and root length (RL), root numbers (RN) and the rate of surviving shoots (SR) (SISL;RL;RN;SR = Parameter(SL;RL;RN;SR) of treated shoots/Parameter(SL;RL;RN;SR) of control shoots x 100) to compare genotypes. In the average of each breeding line and concentration, the osmotic agents resulted in SI values of 40.1, 60.8, 82.6 and 76.0 for SISL, SIRL, SIRN and SISR, respectively. In general, all SI values of C103 and SIRL,RN of C107 were significantly higher than those of the breeding lines. Nine breeding lines were found to be promising based on their final ranking. According to the results, 7.5% and 10% PEG 6000 or 0.2 M and 0.3 M D-mannitol treatments proved to be suitable for the selection of osmotic stress-tolerant genotypes.
Tárgyszavak:	Agrártudományok Növénytermesztési és kertészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk polyethylene glycol D-mannitol tissue culture stress index morphological traits
Megjelenés:	Horticulturae. - 8 : 7 (2022), p. 1-24. -
További szerzők:	Dobránszki Judit (1967-) (biológus) Mendlerné Drienyovszki Nóra (1977-) (agrármérnök) Zsombik László (1976-) (agrármérnök) Magyarné Tábori Katalin (1965-) (kertészmérnök)
Pályázati támogatás:	TKP2021- EGA-20 Egyéb
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