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001-es BibID:	BIBFORM089352
Első szerző:	Árnyas Ervin (biológus-ökológus)
Cím:	Metabolites of Aliphatic Alcohols Detected in Alcoholic Beverages Inhibit Phagocytosis / Ervin M. Árnyas, László Pál, Gergő Baranyi, Orsolya Bujdosó, Gábor Rácz, Róza Ádány, Martin McKee, Sándor Szűcs
Dátum:	2016
ISSN:	0735-0414 1464-3502
Megjegyzések:	Aims: The aim of our study was to measure granulocyte and monocyte phagocytosis following treatment of cells with some metabolites of aliphatic alcohols alone and in combination with acetaldehyde. Methods: The cells were separated from human peripheral blood prior to determination of phagocytosis of opsonized zymosan particles by granulocytes and monocytes treated individually with metabolites of aliphatic alcohols including formaldehyde, 1-propanal, acetone, 1-butanal, and 2-butanone and in combination with acetaldehyde. Results The findings revealed that metabolites of aliphatic alcohols inhibited phagocytosis by granulocytes and monocytes in a concentration-dependent manner and when combined with acetaldehyde, they caused a further decrease in phagocytic activity. Conclusion: Due to their additive effects, it is possible that, in combination with acetaldehyde, metabolites of aliphatic alcohols may inhibit phagocytosis at physiologically realistic concentrations in episodic heavy drinkers, thereby contributing to their increased susceptibility to infectious diseases.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Alcohol And Alcoholism. - 51 : 4 (2016), p. 388-394. -
További szerzők:	Pál László (1987-) (népegészségügyi szakember, egészségfejlesztő) Baranyi Gergő Bujdosó Orsolya (1992-) (népegészségügyi szakember) Rácz Gábor (1982-) (orvos, környezetegészségügyi szakember) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) McKee, Martin Szűcs Sándor (1958-) (biokémikus, vegyész)
Pályázati támogatás:	TÁMOP-4.2.2.A-11/1/KONV-2012-0031 TÁMOP MTA-TKI 2011TKI473 egyéb 1EVJ 1NB0 EGPL 320 egyéb
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001-es BibID:	BIBFORM027662
Első szerző:	Lang, Katrin
Cím:	The composition of surrogate and illegal alcohol products in Estonia / Lang Katrin, Väli Marika, Szűcs Sándor, Ádány Róza, McKee Martin
Dátum:	2006
ISSN:	0735-0414
Megjegyzések:	To identify the composition of illegal and surrogate alcohol products consumed in Estonia. METHODS: The initial source of information was a series of visits made in August 2005 to a soup kitchen in central Tartu, Estonia. Individuals were asked for brief details of their personal circumstances, what they normally drank, and in addition they were asked to bring samples of the substances they usually consumed. In other cases, the substances identified were purchased by the investigators or from informal contacts in north-eastern part of Estonia, an area that is well known for illegal alcohol consumption. Samples were tested for chemical contents. RESULTS: We identified a range of alcohol-containing substances that are consumed, although, not intended for consumption. These comprised medicinal products, aftershaves, illegally produced spirits, and fire-lighting fuel. The medicinal compounds contained, on average, 67% ethanol by volume; the aftershaves contained slightly less. Both were typically pure, with a few containing detectable quantities of isoamyl alcohol. The illegally produced alcohol contained, on average, 43% ethanol by volume, ranging from 32 to 53%. However, many also contained detectable quantities of long chain alcohols. These substances are half the price or less of commercial vodka, with fire lighting fuels especially inexpensive. CONCLUSIONS: There is in Estonia a range of alcohol-containing substances easily available at low cost. Some contain substantially higher concentrations of ethanol than commercial spirits and others also contain toxic long chain alcohols.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Alcohol And Alcoholism. - 41 : 4 (2006), p. 446-450. -
További szerzők:	Väli, Marika Szűcs Sándor (1958-) (biokémikus, vegyész) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos) McKee, Martin
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