CCL

Összesen 9 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM029711
Első szerző:Blasberg, Ronald
Cím:Application of quantitative autoradiographic measurements in experimental brain tumor models / Blasberg R. G., Groothuis D. R., Molnar P.
Dátum:1981
ISSN:0271-8235
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Seminars In Neurology. - 1 : 3 (1981), p. 203-221. -
További szerzők:Groothuis, Dennis Molnár Péter Pál (1951-) (pathológus)
Internet cím:Szerző által megadott URL
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM029710
Első szerző:Blasberg, Ronald
Cím:Regional blood flow in ethylnitrosourea-induced brain tumors / Blasberg Ronald G., Kobayashi Tomowo, Horowitz Marc, Rice J. M., Groothuis Dennis, Molnar Peter, Fenstermacher Joseph D.
Dátum:1983
ISSN:0364-5134
Megjegyzések:Regional blood flow was measured in experimental brain tumors using iodoantipyrine labeled with carbon 14 and quantitative autoradiography. A total of fifteen oligodendrogliomas, sixteen mixed gliomas, one astrocytoma, one ependymoma, and three malignant schwannomas were studied in 9 rats. The mean tumor blood flows for all glioma classifications were similar, averaging 45 +/- 3 (standard error of the mean) ml . hg-1 . min-1. Flow was fairly uniform within individual oligodendrogliomas and there was no apparent correlation between blood flow and tumor size or location. The mixed gliomas were larger than the oligodendrogliomas and had a wider range of blood flow. Small focal areas of necrosis were observed in 7 mixed gliomas, and low flows were usually measured in these regions; these flows were not always the lowest regional values measured within the mixed gliomas or total group of tumors, however. Small tumor regions with increased vascularity, frequently with endothelial cell proliferation, were observed in oligodendrogliomas and to a greater extent in mixed gliomas; these regions were correlated with small elevations in blood flow (10 to 15 ml . hg-1 . min-1) in comparison with surrounding tumor tissue. Brain adjacent to tumor usually had higher blood flows than that in tumor periphery. Hemispheric differences in blood flow related to the site of primary tumor growth were not observed.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Annals Of Neurology. - 14 : 2 (1983), p. 189-201. -
További szerzők:Kobayashi, Tomowo Horowitz, Marc Rice, Jerry M. Groothuis, Dennis Molnár Péter Pál (1951-) (pathológus) Fenstermacher, Joseph D.
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM029709
Első szerző:Blasberg, Ronald
Cím:Regional blood-to-tissue transport in ethylnitrosourea-induced brain tumors / Blasberg R. G., Kobayashi T., Horowitz M., Rice J. M., Groothuis D., Molnar P., Fenstermacher J. D.
Dátum:1983
ISSN:0364-5134
Megjegyzések:Regional blood-to-tissue transport, expressed as a unidirectional transfer rate constant (K), was measured in experimental brain tumors using alpha-aminoisobutyric acid (AIB) labeled with carbon 14 and quantitative autoradiography. A total of sixteen oligodendrogliomas, four mixed gliomas, three astrocytomas, two diffuse gliomatosis, one anaplastic astrocytoma, one ependymoma and four malignant schwannomas were studied in 9 rats. The mean Ks for all glioma classifications were similar, averaging 2.6 +/- 0.4 (standard error of the mean) ml . kg-1 . min-1, and were only slightly higher than those for nontumorous parietal cortex (2.1 ml . kg-1 . min-1), corpus callosum (0.9 ml . kg-1 . min-1), and a comparable region of brain tissue in the contralateral hemisphere (1.3 ml . kg-1 . min-1). Values of K varied minimally in the intracerebral gliomas and were marginally correlated with tumor cell morphology in only two tumors. In some (but not all) of the larger gliomas, increased vascularity, with or without endothelial proliferation, was associated with a 3- to 15-fold increase in K. Regional K values in malignant schwannomas were highly variable (4 to 207 ml . kg-1 . min-1) and generally were not correlated with specific histological features of the tumor, except in some regions with increased vascularity. Estimates of the average fractional extraction of AIB by the intracranial gliomas and malignant schwannomas were 0.01 and 0.2, respectively; average fractional extractions for nontumorous brain were approximately 0.003.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Annals Of Neurology. - 14 : 2 (1983), p. 202-215. -
További szerzők:Kobayashi, Tomowo Horowitz, Marc Rice, Jerry M. Groothuis, Dennis Molnár Péter Pál (1951-) (pathológus) Fenstermacher, Joseph D.
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM029685
Első szerző:Groothuis, Dennis
Cím:Regional blood flow in avian sarcoma virus (ASV)-induced brain tumors / Groothuis D., Blasberg R. G., Molnár P., Bigner D., Fenstermacher J. D.
Dátum:1983
ISSN:0340-5354
Megjegyzések:Regional blood flow (F) was measured in avian sarcoma virus (ASV)-induced brain tumors in rats. Blood flow was variable in individual as well as different tumors; tumor F did not correlate with histologic classification, tumor size, central versus peripheral tumor regions, intraparenchymal location, cell density, or specific cytologic characteristics. Low values of F did correlate with tumor necrosis and hydrocephalus; high values of F correlated with tumorous invasion or association with choroid plexus. Mean tumor F was not significantly different from that of the same anatomic, tumor-free brain region of the contralateral hemisphere, but F in brain tissue adjacent to the tumor was depressed significantly. Depression of F was observed in tumor-free cortex and corpus callosum, especially in the hemisphere ipsilateral to the main tumor mass and in those animals with hydrocephalus.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Neurology. - 33 : 6 (1983), p. 686-696. -
További szerzők:Blasberg, Ronald Molnár Péter Pál (1951-) (pathológus) Bigner, Darell Fenstermacher, Joseph D.
Borító:

5.

001-es BibID:BIBFORM055459
Első szerző:Molnár Péter Pál (pathológus)
Cím:Primary Intracranial eosinophilic chloroma (EMT) / P. P. Molnár, T. Németh, L. Rejtő, B. Telek, Gy. Csécsei
Dátum:2001
Tárgyszavak:Orvostudományok Elméleti orvostudományok idézhető absztrakt
Megjelenés:Journal of Neuropathology and Experimental Neurology. - 60 (2001), p. 451. -
További szerzők:Németh Tamás (patológus) Rejtő László (1963-) (belgyógyász, haematológus) Telek Béla (1948-) (belgyógyász, haematológus) Csécsei György (1948-2005) (idegsebész)
Borító:

6.

001-es BibID:BIBFORM055311
Első szerző:Molnár Péter Pál (pathológus)
Cím:Adjacent astrocytoma and ependymoma : dependent mixed neoplasia or unusual collision tumors? / Péter Molnár, Katalin Hegedüs
Dátum:1984
ISSN:0090-3019
Megjegyzések:Concurrent neoplastic transformation of different cellular elements resulting in an intraventricular and intraparenchymal tumor is described. An infiltrating astrocytoma of the left frontal lobe had been partially removed from a 43-yr-old woman. Four months later she died, and the autopsy revealed a recurrent astrocytoma and a closely apposed large intraventricular ependymoma. Both light microscopy and ultrastructural findings established the different nature of the two tumors. Theoretically they could represent collision or composite tumors. Another possibility would be that a relatively longstanding ependymoma induced the astrocytic neoplasm. The clinical history and the sequential morphological analysis, i.e., biopsy and autopsy sampling suggest that the ependymoma developed due to the inductive influence of the astrocytic growth.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Surgical Neurology. - 22 : 5 (1984), p. 455-460. -
További szerzők:Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

7.

001-es BibID:BIBFORM029686
Első szerző:Molnár Péter Pál (pathológus)
Cím:Regional blood-to-tissue transport in avian sarcoma virus (ASV)-induced brain tumors / Molnar P., Blasberg R. G., Groothuis D., Bigner D., Fenstermacher J. D.
Dátum:1983
ISSN:0340-5354
Megjegyzések:Regional blood-to-tissue transport of 14C-alpha-aminoisobutyric acid (AIB) was measured in avian sarcoma virus (ASV)-induced rat brain tumors and expressed as a unidirectional transfer rate constant (K). The magnitude of K was variable and did not correlate with histologic classification or specific features of the tumors, with the possible exception of sarcomas. Averaged mean K was highest for anaplastic astrocytomas and lowest for gemistocytic astrocytomas (GA); however, the range of measurement within the individual tumor classifications (except GA) was broad. K was not consistently related to tumor size or tumor location; choroid plexus and subependymal tumors were exceptions and had higher K values. The averaged mean K of tumor-free brain in the contralateral hemisphere (CBA) was comparable to that of control animals. The averaged mean K in brain adjacent to tumor was greater than in CBA and generally one-third to one-half of the value in tumor periphery, indicating that these tumors affect the permeability characteristics of adjacent brain capillaries. Estimates of the fractional extraction (E) of AIB by the tumors ranged between 0.009 and 0.2; E's in this range indicate that tumor capillaries are not freely permeable to this solute.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Neurology. - 33 : 6 (1983), p. 702-711. -
További szerzők:Blasberg, Ronald Groothuis, Dennis Bigner, Darell Fenstermacher, Joseph D.
Borító:

8.

001-es BibID:BIBFORM040698
Első szerző:Novák László (idegsebész)
Cím:Does increased 18FDG uptake reflect malignant transformation of a low-grade glioma? : a diagnostic dilemma / Novák, L., Molnar, P., Lengyel, Z., Tron, L.
Dátum:2005
ISSN:0028-3886
Megjegyzések:Benign gliomas of the brain show decreased uptake of 18F fluorodeoxyglucose (FDG) on positron emission tomography (PET). Malignant transformation is usually manifested by an increase of 18FDG uptake. A 45-year-old female has been followed up since 1987 by means of 18FDG-PET for a right hemispheric World Health Organization Grade II oligoastrocytoma. In 1996, increased epileptic activity was accompanied by increased 18FDG uptake within the temporal part of the tumor. After surgery, the epileptic seizures diminished. Histological examination of the resected tumor showed no change in the pathology when compared with the first biopsy. Localized temporal increase of 18FDG uptake was not associated with malignant progression. The decrease of seizure frequency might shed light on a putative connection of hyperglycolysis and epileptic discharges.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Neurology India. - 53 : 1 (2005), p. 112-114. -
További szerzők:Molnár Péter Pál (1951-) (pathológus) Lengyel Zsolt (nukleáris medicina szakorvos) Trón Lajos (1941-) (biofizikus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

9.

001-es BibID:BIBFORM029740
Első szerző:Warnke, Peter C.
Cím:Intravenous adenosine selectively increases blood flow to xenotransplanted intracerebral gliomas / Warnke P. C., Molnar P., Bigner D. D., Heistad D. H., Groothuis D. R.
Dátum:1987
ISSN:0028-3878
Megjegyzések:Adenosine was infused intravenously at 10 mumol/(kg.min) into athymic ("nude") rats with intracerebral D-54MG xenotransplanted brain tumors, in an attempt to increase tumor blood flow. Cerebral blood flow (F) was measured with 14C-iodoantipyrine and quantitative autoradiography. Mean arterial blood pressure was 95 +/- 9.4 (SE) mm Hg in the adenosine group and 112 +/- 6.0 mm Hg in the controls. Averaged mean whole tumor F was significantly higher in adenosine-treated brain tumors (117.6 +/- 20.8 ml/[hg.min]) than in controls (62.2 +/- 9.7 ml/[hg.min]). Regionally, there were significant increases of F in tumor periphery and brain around tumor, but not in tumor center or any tumor-free brain regions. Focal values of F less than 5 ml/(hg.min) were present in some necrotic regions of adenosine-treated tumors. These results, obtained in unanesthetized rats with transplanted gliomas from a human cell line, confirm our earlier observations in avian sarcoma virus-induced brain sarcomas in dogs, and suggest that adenosine or perhaps other vasodilators could be used to selectively increase the delivery of lipid-soluble chemotherapeutic drugs to brain tumors.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Neurology. - 37 : 12 (1987), p. 1870-1873. -
További szerzők:Molnár Péter Pál (1951-) (pathológus) Bigner, Darell Heistad, D. H. Groothuis, Dennis
Borító:
Rekordok letöltése1