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1.

001-es BibID:BIBFORM088207
Első szerző:Demcsák Alexandra
Cím:Acid suppression therapy, gastrointestinal bleeding and infection in acute pancreatitis - An international cohort study / Alexandra Demcsak, Alexandra Soos, Lilla Kincses, Ines Capunge, Georgi Minkov, Mila Kovacheva-Slavova, Radislav Nakov, Dong Wu, Wei Huang, Qing Xia, Lihui Deng, Marcus Hollenbach, Alexander Schneider, Michael Hirth, Orestis Ioannidis, Aron Vincze, Judit Bajor, Patrícia Sarlos, Laszló Czakó, Dora Illés, Ferenc Izbeki, Laszló Gajdán, Maria Papp, Jozsef Hamvas, Marta Varga, Peter Kanizsai, Ernő Bóna, Alexandra Miko, Szilard Váncsa, Márk Félix Juhász, Klementina Ocskay, Erika Darvasi, Emőke Miklós, Balint Erőss, Andrea Szentesi, Andrea Parniczky, Riccardo Casadei, Claudio Ricci, Carlo Ingaldi, Laura Mastrangelo, Elio Jovine, Vincenzo Cennamo, Marco V. Marino, Giedrius Barauskas, Povilas Ignatavicius, Mario Pelaez-Luna, Andrea Soriano Rios, Svetlana Turcan, Eugen Tcaciuc, Ewa Małecka-Panas, Hubert Zatorski, Vitor Nunes, Antonio Gomes, Tiago Cúrdia Gonçalves, Marta Freitas, Júlio Constantino, Milene Sa, Jorge Pereira, Bogdan Mateescu, Gabriel Constantinescu, Vasile Sandru, Ionut Negoi, Cezar Ciubotaru, Valentina Negoita, Stefania Bunduc, Cristian Gheorghe, Sorin Barbu, Alina Tantau, Marcel Tantau, Eugen Dumitru, Andra Iulia Suceveanu, Cristina Tocia, Adriana Gherbon, Andrey Litvin, Natalia Shirinskaya, Yliya Rabotyagova, Mihailo Bezmarevic, Péter Jenő Hegyi, Jimin Han, Juan Armando Rodriguez-Oballe, Isabel Miguel Salas, Eva Pijoan Comas, Daniel de la Iglesia Garcia, Andrea Jardi Cuadrado, Adriano Quiroga Castineira, Yu-Ting Chang, Ming-Chu Chang, Ali Kchaou, Ahmed Tlili, Sabite Kacar, Volkan Gokbulut, Deniz Duman, Haluk Tarik Kani, Engin Altintas, Serge Chooklin, Serhii Chuklin, Amir Gougol, George Papachristou, Peter Hegyi Jr.
Dátum:2020
ISSN:1424-3903
Megjegyzések:Background:Acid suppressing drugs (ASD) are generally used in acute pancreatitis (AP); however, largecohorts are not available to understand their efficiency and safety. Therefore, our aims were to evaluatethe association between the administration of ASDs, the outcome of AP, the frequency of gastrointestinal(GI) bleeding and GI infection in patients with AP.Methods:We initiated an international survey and performed retrospective data analysis on AP patientshospitalized between January 2013 and December 2018.Results:Data of 17,422 adult patients with AP were collected from 59 centers of 23 countries. We foundthat 23.3% of patients received ASDs before and 86.6% during the course of AP. ASDs were prescribed to57.6% of patients at discharge. ASD administration was associated with more severe AP and highermortality. GI bleeding was reported in 4.7% of patients, and it was associated with pancreatitis severity,mortality and ASD therapy. Stool culture test was performed in 6.3% of the patients with 28.4% positiveresults.Clostridium difficilewas the cause of GI infection in 60.5% of cases. Among the patients with GIinfections, 28.9% received ASDs, whereas 24.1% were without any acid suppression treatment. GI infec-tion was associated with more severe pancreatitis and higher mortality.Conclusions:Although ASD therapy is widely used, it is unlikely to have beneficial effects either on theoutcome of AP or on the prevention of GI bleeding during AP. Therefore, ASD therapy should be sub-stantially decreased in the therapeutic management of AP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Acid suppressing drug
Gastrointestinal bleeding
Gastrointestinal infection
Acute pancreatitis
Proton pump inhibitor
Megjelenés:Pancreatology. - 20 : 7 (2020), p. 1323-1331. -
További szerzők:Soós Alexandra Kincses Lilla Capunge, Ines Minkov, Georgi Kovacheva-Slavova, Mila Nakov, Radislav Wu, Dong Huang, Wei Xia, Qing Deng, Lihui Hollenbach, Marcus Schneider, Alexander Hirth, Michael Ioannidis, Orestis Vincze Áron Bajor Judit Sarlós Patrícia Czakó László Illés Dóra Izbéki Ferenc Gajdán László Papp Mária (1975-) (belgyógyász, gasztroenterológus) Hamvas József Varga Márta Kanizsai Péter Bóna Ernő Mikó Alexandra Váncsa Szilárd Juhász Márk Félix Ocskay Klementina Darvasi Erika Miklós Emőke Erőss Bálint Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Casadei, Riccardo Ricci, Claudio Ingaldi, Carlo Mastrangelo, Laura Jovine, Elio Cennamo, Vincenzo Marino, Marco Vito Barauskas, Giedrius Ignatavicius, Povilas Pelaez-Luna, Mario Rios, Andrea Soriano Turcan, Svetlana Tcaciuc, Eugen Małecka-Panas, Ewa Zatorski, Hubert Nunes, Vitor Gomes, António Pedro Gonçalves, Tiago Cúrdia Freitas, Marta Constantino, Júlio Sá, Milene Pereira, Jorge Mateescu, Bogdan Constantinescu, Gabriel Sandru, Vasile Negoi, Ionut Ciubotaru, Cezar Negoita, Valentina Bunduc, Stefania Gheorghe, Cristian Barbu, Sorin Tantau, Alina Tantau, Marcel Dumitru, Eugen Suceveanu, Andra Iulia Tocia, Cristina Gherbon, Adriana Litvin, A. Andrey Shirinskaya, Natalia V. Rabotyagova, Yliya Bezmarevic, Mihailo Hegyi Péter Jenő (belgyógyász) Han, Jimin Rodriguez-Oballe, Juan Armando Salas, Isabel Miguel Comas, Eva Pijoan Garcia, Daniel de la Iglesia Cuadrado, Andrea Jardi Castiñeira, Adriano Quiroga Chang, Yu-Ting Chang, Ming-Chu Kchaou, Ali Tlili, Ahmed Kacar, Sabite Gökbulut, Volkan Duman, Deniz Kani, Haluk Tarik Altintas, Engin Chooklin, Serge Chuklin, Serhii Gougol, Amir Papachristou, Georgios I. Hegyi Péter Jr. (belgyógyász)
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2.

001-es BibID:BIBFORM082673
035-os BibID:(cikkazonosító)1092 (WoS)000483784200001 (Scopus)85072948362
Első szerző:Farkas Nelli
Cím:A Multicenter, International Cohort Analysis of 1435 Cases to Support Clinical Trial Design in Acute Pancreatitis / Nelli Farkas, Lilla Hanák, Alexandra Mikó, Judit Bajor, Patrícia Sarlós, József Czimmer, Áron Vincze, Szilárd Gódi, Dániel Pécsi, Péter Varjú, Katalin Márta, Péter Jenő Hegyi, Bálint Erőss, Zsolt Szakács, Tamás Takács, László Czakó, Balázs Németh, Dóra Illés, Balázs Kui, Erika Darvasi, Ferenc Izbéki, Adrienn Halász, Veronika Dunás-Varga, László Gajdán, József Hamvas, Mária Papp, Ildikó Földi, Krisztina Eszter Fehér, Márta Varga, Klára Csefkó, Imola Török, Farkas Hunor-Pál, Artautas Mickevicius, Elena Ramirez Maldonado, Ville Sallinen, János Novák, Ali Tüzün Ince, Shamil Galeev, Barnabás Bod, János Sümegi, Petr Pencik, Attila Szepes, Andrea Szentesi, Andrea Párniczky, Péter Jr. Hegyi, Hungarian Pancreatic Study Group
Dátum:2019
ISSN:1664-042X
Megjegyzések:Background: C-reactive protein level (CRP) and white blood cell count (WBC) have been variably used in clinical trials on acute pancreatitis (AP). We assessed their potential role. Methods: First, we investigated studies which have used CRP or WBC, to describe their current role in trials on AP. Second, we extracted the data of 1435 episodes of AP from our registry. CRP and WBC on admission, within 24 h from the onset of pain and their highest values were analyzed. Descriptive statistical tools as Kruskal?Wallis, Mann? Whitney U, Levene's F tests, Receiver Operating Characteristic (ROC) curve analysis and AUC (Area Under the Curve) with 95% confidence interval (CI) were performed. Results: Our literature review showed extreme variability of CRP used as an inclusion criterion or as a primary outcome or both in past and current trials on AP. In our cohort, CRP levels on admission poorly predicted mortality and severe cases of AP; AUC: 0.669 (CI:0.569?0.770); AUC:0.681 (CI: 0.601?0.761), respectively. CRP levels measured within 24 h from the onset of pain failed to predict mortality or severity; AUC: 0.741 (CI:0.627?0.854); AUC:0.690 (CI:0.586?0.793), respectively. The highest CRP during hospitalization had equally poor predictive accuracy for mortality and severity AUC:0.656 (CI:0.544?0.768); AUC:0.705 (CI:0.640?0.769) respectively. CRP within 24 h from the onset of pain used as an inclusion criterion markedly increased the combined event rate of mortality and severe AP (13% for CRP > 25 mg/l and 28% for CRP > 200 mg/l). Conclusion: CRP within 24 h from the onset of pain as an inclusion criterion elevates event rates and reduces the number of patients required in trials on AP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
acute pancreatitis
C-reactive protein
white blood cell
trial design
sample size calculation
Megjelenés:Frontiers in Physiology. - 10 (2019), p. 1-12. -
További szerzők:Hanák Lilla Mikó Alexandra Bajor Judit Sarlós Patrícia Czimmer József Vincze Áron Gódi Szilárd Pécsi Dániel Varjú Péter Márta Katalin Hegyi Péter Jenő (belgyógyász) Erőss Bálint Szakács Zsolt Takács Tamás (Szeged) Czakó László Németh Balázs Tamás Illés Dóra Kui Balázs Darvasi Erika Izbéki Ferenc Halász Adrienn Dunás-Varga Veronika Gajdán László Hamvas József Papp Mária (1975-) (belgyógyász, gasztroenterológus) Földi Ildikó (1981-) (orvos) Fehér Krisztina Eszter Varga Márta Csefkó Klára Török Imola Farkas Hunor Mickevicius, Artautas Maldonado, Elena Ramirez Sallinen, Ville Novák János Ince, Ali Tüzün Galeev, Shamil Bod Barnabás Sümegi János Pencik, Petr Szepes Attila (Szeged) Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Hegyi Péter Jr. (belgyógyász) Hungarian Pancreatic Study Group
Pályázati támogatás:GINOP 2.3.2-15-2016-00048
GINOP
EFOP-3.6.2-16-2017-00006
EFOP
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3.

001-es BibID:BIBFORM090166
Első szerző:Hágendorn Roland
Cím:Disturbance of consciousness deteriorates the severity of acute pancreatitis. An international multicentre cohort analyses of 1220 prospectively collected patients / R. Hagendorn, Á. Vincze, F. Izbeki, L. Gajdan, S. Godi, A. Illes, P. Sarlos, N. Farkas, B. Erős, V. Lillik, D. Illes, P. Varjú, K. Marta, I. Török, M. Papp, Z. Vitalis, B. Bod, J. Hamvas, Z. Szepes, T. Takacs, L. Czakó, A. Szentesi, A. Parniczky, P. Hegyi, A. Miko
Dátum:2020
ISSN:1424-3903
Megjegyzések:Purpose: Disturbance of consciousness (DOC) may develop in acute pancreatitis (AP). In clinical practice, it is known that DOC may worsen the patient's condition, but we have no exact data on how DOC affects the outcome of AP. Materials and methods: From the Hungarian Pancreatic Study Groups' AP registry, 1220 cases contained the exact data on DOC. Patients were separated to Non-DOC and DOC, whereas DOC was further divided into non-alcohol related DOC (Non-ALC DOC) and ALC-DOC groups. Statistical analysis was performed by SPSS 24 Software Package. Results: From the 1220 patients, 47 (3.85%) developed DOC, 23 (48.9%) cases were ALC DOC vs. 24 (51.1%) Non-ALC DOC. The incidence of severe AP was higher in the DOC compared to the Non-DOC group (19.15% vs. 5.29%, p<0.001). The mortality was higher in the DOC vs. Non-DOC group (14.89% vs. 1.71%, p<0.001). Length of hospitalization (LOH) was longer in the DOC vs. non-DOC group (Me:11; IQR:8-17 days vs. Me:9; IQR:6-13 days, p?0.049). Patients with ALC DOC developed more frequently moderately-severe AP vs. Non-ALC DOC (43.48% vs. 12.5%), while the incidence of severe AP was significantly higher in Non-ALC vs. ALC DOC group (33.33% vs. 4.35%) (p<0.001). LOH showed tendency to be longer in Non-ALC DOC compared to ALC DOC respectively (Me:13; IQR:7-20 days vs. Me:9.5; IQR:8-15.5 days, p?0.119). Conclusions: DOC during AP is associated with a higher rate of moderate and severe AP and increases the risk of mortality; therefore, the DOC should be closely monitored and prevented in AP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Pancreatology. - 20 (2020), p. S25. -
További szerzők:Vincze Áron Izbéki Ferenc Gajdán László Gódi Szilárd Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Sarlós Péter Farkas Nelli Erős Bálint Lillik Veronika Illés Dóra Varjú Péter Márta Katalin Török I. Papp Mária (1975-) (belgyógyász, gasztroenterológus) Vitális Zsuzsanna (1963-) (belgyógyász, gasztroenterológus) Bod Barnabás Hamvas József Szepes Zoltán Takács T. Czakó László Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Hegyi Péter Jenő (belgyógyász) Mikó Alexandra
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4.

001-es BibID:BIBFORM085501
Első szerző:Hágendorn Roland
Cím:Development of disturbance of consciousness is associated with increased severity in acute pancreatitis / Roland Hágendorn, Áron Vincze, Ferenc Izbéki, László Gajdán, Szilárd Gódi, Anita Illés, Patrícia Sarlós, Nelli Farkas, Bálint Erőss, Veronika Lillik, Dóra Illés, Péter Varjú, Katalin Márta, Imola Török, Mária Papp, Zsuzsanna Vitális, Barnabás Bod, József Hamvas, Zoltán Szepes, Tamás Takács, László Czakó, Zsolt Márton, Andrea Szentesi, Andrea Párniczky, Péter Hegyi, Alexandra Mikó
Dátum:2020
ISSN:1424-3903
Megjegyzések:Background Disturbance of consciousness (DOC) may develop in acute pancreatitis (AP). In clinical practice, it is known that DOC may worsen the patient's condition, but we have no exact data on how DOC affects the outcome of AP. Methods From the Hungarian Pancreatic Study Groups' AP registry, 1220 prospectively collected cases were analysed, which contained exact data on DOC, included patients with confusion, delirium, convulsion, and alcohol withdrawal, answering a post hoc defined research question. Patients were separated to Non-DOC and DOC, whereas DOC was further divided into non-alcohol related DOC (Non-ALC DOC) and ALC DOC groups. For statistical analysis, independent sample t-test, Mann-Whitney, Chi-squared, or Fisher exact test were used. Results From the 1220 patients, 47 (3.9%) developed DOC, 23 (48.9%) cases were ALC DOC vs. 24 (51.1%) Non-ALC DOC. Analysis between the DOC and Non-DOC groups showed a higher incidence of severe AP (19.2% vs. 5.3%, p<0.001), higher mortality (14.9% vs. 1.7%, p<0.001), and a longer length of hospitalization (LOH) (Me=11; IQR: 8-17 days vs. Me=9; IQR: 6-13 days, p=0.049) respectively. Patients with ALC DOC developed more frequently moderate AP vs. Non-ALC DOC (43.5% vs. 12.5%), while the incidence of severe AP was higher in Non-ALC vs. ALC DOC group (33.3% vs. 4.4%) (p<0.001). LOH showed a tendency to be longer in Non-ALC DOC compared to ALC DOC, respectively (Me:13; IQR:7-20 days vs. Me:9.5; IQR:8-15.5 days, p=0.119). Conclusion DOC during AP is associated with a higher rate of moderate and severe AP and increases the risk of mortality.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
disturbance of consciousness
acute pancreatitis
alcohol
delirium
mortality
Megjelenés:Pancreatology. - 20 : 5 (2020), p. 806-812. -
További szerzők:Vincze Áron Izbéki Ferenc Gajdán László Gódi Szilárd Illés Anita Sarlós Patrícia Farkas Nelli Erőss Bálint Lillik Veronika Illés Dóra Varjú Péter Márta Katalin Török Imola Papp Mária (1975-) (belgyógyász, gasztroenterológus) Vitális Zsuzsanna (1963-) (belgyógyász, gasztroenterológus) Bod Barnabás Hamvas József Szepes Zoltán Takács Tamás (Szeged) Czakó László Márton Zsolt Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Hegyi Péter Jenő (belgyógyász) Mikó Alexandra
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5.

001-es BibID:BIBFORM090160
035-os BibID:(cikkazonosító)1367 (WOS)000626774100081 (Scopus)85099483306
Első szerző:Hegyi Péter Jr. (belgyógyász)
Cím:Evidence for diagnosis of early chronic pancreatitis after three episodes of acute pancreatitis : a cross-sectional multicentre international study with experimental animal model / Péter J. Hegyi, Alexandra Soós, Emese Tóth, Attila Ébert, Viktória Venglovecz, Katalin Márta, Péter Mátrai, Alexandra Mikó, Judit Bajor, Patrícia Sarlós, Áron Vincze, Adrienn Halász, Ferenc Izbéki, Zoltán Szepes, László Czakó, György Kovács, Mária Papp, Zsolt Dubravcsik, Márta Varga, József Hamvas, Balázs C. Németh, Melania Macarie, Ali Tüzüm Ince, Elena A. Dubtsova, Mariya A. Kirynkova, Igor E. Khatkov, Tanya Bideeva, Artautas Mickevicius, Elena Ramírez-Maldonado, Ville Sallinen, Bálint Erős, Dániel Pécsi, Andrea Szentesi, Andrea Párniczky, László Tiszlavicz, Péter Hegyi
Dátum:2021
ISSN:2045-2322
Megjegyzések:Abstract Chronic pancreatitis (CP) is an end-stage disease with no specific therapy; therefore, an early diagnosis is of crucial importance. In this study, data from 1315 and 318 patients were analysed from acute pancreatitis (AP) and CP registries, respectively. The population from the AP registry was divided into AP (n = 983), recurrent AP (RAP, n = 270) and CP (n = 62) groups. The prevalence of CP in combination with AP, RAP2, RAP3, RAP4 and RAP5 + was 0%, 1%, 16%, 50% and 47%, respectively, suggesting that three or more episodes of AP is a strong risk factor for CP. Laboratory, imaging and clinical biomarkers highlighted that patients with RAP3 + do not show a significant difference between RAPs and CP. Data from CP registries showed 98% of patients had at least one AP and the average number of episodes was four. We mimicked the human RAPs in a mouse model and found that three or more episodes of AP cause early chronic-like morphological changes in the pancreas. We concluded that three or more attacks of AP with no morphological changes to the pancreas could be considered as early CP (ECP).The new diagnostic criteria for ECP allow the majority of CP patients to be diagnosed earlier. They can be used in hospitals with no additional costs in healthcare.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Scientific Reports. - 11 : 1 (2021), p. 1-14. -
További szerzők:Soós Alexandra Tóth Emese Ébert Attila Venglovecz Viktória Márta Katalin Mátrai Péter Mikó Alexandra Bajor Judit Sarlós Patrícia Vincze Áron Halász Adrienn Izbéki Ferenc Szepes Zoltán Czakó László Kovács György (1982-) (belgyógyász, gasztroenterológus) Papp Mária (1975-) (belgyógyász, gasztroenterológus) Dubravcsik Zsolt (belgyógyász, gasztroenterológus) Varga Márta Hamvas József Németh Balázs Csaba Macarie, Melania Ince, Ali Tüzün Dubtsova, Elena A. Kirynkova, Mariya A. Khatkov, Igor E. Bideeva, Tanya Mickevicius, Artautas Ramírez-Maldonado, Elena Sallinen, Ville Erős Bálint Pécsi Dániel Szentesi Andrea Párniczky Andrea (gyermekgyógyász) Tiszlavicz László Hegyi Péter Jenő (belgyógyász)
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6.

001-es BibID:BIBFORM070012
035-os BibID:e015874
Első szerző:Márta Katalin
Cím:High versus low energy administration in the early phase of acute pancreatitis (GOULASH trial) : protocol of a multicentre randomized double-blind clinical trial / Katalin Márta, Anikó Nóra Szabó, Dániel Pécsi, Péter Varjú, Judit Bajor, Szilárd Gódi, Patrícia Sarlós, Alexandra Mikó, Katalin Szemes, Mária Papp, Tamás Tornai, Áron Vincze, Zsolt Márton, Patrícia Anna Vincze, Erzsébet Lankó, Andrea Szentesi, Tímea Molnár, Roland Hagendorn, Faluhelyi Nándor, István Battyáni, Dezső Kelemen, Róbert Papp, Attila Miseta, Verzár Zsófia, Markus M. Lerch, Johan P. Neoptoleomos, Miklós Sain-Tóth, Ole H. Petersen, Peter Hegyi
Dátum:2017
ISSN:2044-6055
Megjegyzések:Introduction. Acute pancreatitis (AP) is an inflammatory disease with no specific therapy. Mitochondrial injury followed by ATP depletion in both acinar and ductal cells is a recently discovered early event in the pathogenesis. Importantly, preclinical research showed that intracellular ATP delivery restores the physiological function of the cells and protects from cell injury suggesting that restoration of energy levels in the pancreas is therapeutically beneficial. Despite several, high quality and experimental observations in this area, no randomized trials have been conducted to date to address the requirements for energy intake in the early phase of AP. Methods/Design. This is a randomized, controlled two-arms double-blind multicentre trial. Patients suffering from AP will be randomly assigned to groups A (30 kcal/kg/day energy administration starting within 24h of hospital admission) or B (low energy administration during the first 72h of hospital admission). Energy will be delivered with nasoenteric tube feeding with additional intravenous glucose supplementation or total parenteral nutrition if necessary. A combination of multi organ failure for more than 48h and mortality is defined as the primary endpoint, whereas several secondary endpoints such as length of hospitalization or pain will be determined to elucidate more detailed differences between the groups. The general feasibility, safety and quality checks required for high quality evidence will be adhered to.Ethics and Dissemination. The study has been approved by the relevant organization, The Scientific and Research Ethics Committee of the Hungarian Medical Research Council (55961- 2/2016/EKU). This study will provide evidence whether early high-energy nutritional support is beneficial in the clinical management of AP. The results of this trial will be published in an open access way and disseminated among medical doctors.Trial registration: The trial has been registered at the ISRCTN (ISRTCN 63827758).
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
acute pancreatitis
energy administration
enteral feeding
randomized clinical trial
Megjelenés:BMJ Open. - 7 : 9 (2017), p. 1-9. -
További szerzők:Szabó Anikó Nóra Pécsi Dániel Varjú Péter Bajor Judit Gódi Szilárd Sarlós Patrícia Mikó Alexandra Szemes Katalin Papp Mária (1975-) (belgyógyász, gasztroenterológus) Tornai Tamás István (1984-) (belgyógyász) Vincze Áron Márton Zsolt Vincze Patrícia Anna Lankó Erzsébet Szentesi Andrea Molnár Tímea Hágendorn Roland Faluhelyi Nándor Battyáni István Kelemen Dezső Papp Róbert Miseta Attila Verzár Zsófia Lerch, Markus M. Neoptoleomos, Johan P. Sain-Tóth, Miklós Petersen, Ole H. Hegyi Péter Jenő (belgyógyász)
Pályázati támogatás:GINOP-2.3.2-15-2016-00015
GINOP
KH-125678
NKFI
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7.

001-es BibID:BIBFORM090171
Első szerző:Mikó Alexandra
Cím:Early Phase of Chronic Pancreatitis : results of the First 20 Months of the GOULASH-PLUS Clinical Study / A. Mikó, D. Kato, V. Lillik, L. Gajdán, M. Papp, I. Földi, B. Bodis, N. Faluhelyi, P. Sarlos, Á. Vincze, Z. Szepes, G. Elsayed, P. Mosler, B. Erős, L. Czakó, P. Hegyi
Dátum:2020
ISSN:1424-3903
Megjegyzések:Purpose: Acute pancreatitis (AP) is a severe inflammatory disease that can lead to irreversible complications such as recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP). CP is often diagnosed in an advanced form, though it could be effectively managed at an early stage. However, parameters indicative of early CP are still unknown. We aim to find measurable biomarkers and clinical signs of this early phase through the GOULASH-PLUS follow-up study. Materials and methods: GOULASH-PLUS is a longitudinal study of AP with a 6-year follow-up of patients with a well documented episode of AP. Imaging, physical and laboratory testing is performed annually. To detect endocrine function, blood glucose, HbA1C were measured, and oral glucose tolerance test (OGTT) was performed; exocrine parameters were measured by a stool elastase test. Chi-square test and Fisher exact test were used for statistical analysis. Results: Of the first 133 patients, 57 (43%)were women, 76 (57%)were men, and the average age was 55. 27 (20%) patients had moderate AP, 6 (5%) had severe AP, and 15 (14%) had RAP in the first year. 13 (16%) patients were diagnosed with severe exocrine pancreas insufficiency, 17 (15%) were diagnosed with diabetes and 23 (20%) with impaired glucose tolerance (IGT). Exocrine abnormalities were present in 70% of patients with RAP, compared with only 18% in the group without RAP (p <0.001). There was no difference in endocrine function between RAP and non-RAP groups. Based on OGTT, hyperinsulinemia was detected in IGT and diabetic groups, and endocrine disruption (IGT, DM) was not associated with AP severity. Conclusions: One year after AP, exocrine and endocrine insufficiency can be measured in the majority of patients. In RAP, exocrine abnormalities appear earlier, while the endocrine function is not affected. The development of IGT and DM is independent of the severity of AP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:Pancreatology. - 20 (2020), p. S29. -
További szerzők:Kató D. Lillik V. Gajdán László Papp Mária (1975-) (belgyógyász, gasztroenterológus) Földi Ildikó (1981-) (orvos) Bódis Beáta Faluhelyi Nándor Sarlós Patrícia Vincze Áron Szepes Zoltán Elsayed, G. Mosler, P. Erős Bálint Czakó László Hegyi Péter Jenő (belgyógyász)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

8.

001-es BibID:BIBFORM078557
035-os BibID:(cikkazonosító)e025500
Első szerző:Mikó Alexandra
Cím:Observational longitudinal multicentre investigation of acute pancreatitis. (GOULASH PLUS) : follow-up of the GOULASH-study, protocol / Alexandra Mikó, Bálint Erőss, Patrícia Sarlós, Péter Hegyi Jr., Katalin Márta, Dániel Pécsi, Áron Vincze, Beáta Bódis, Orsolya Nemes, Nándor Faluhelyi, Orsolya Farkas, Róbert Papp, Dezső Kelemen, Andrea Szentesi, Eszter Hegyi, Mária Papp, László Czakó, Ferenc Izbéki, László Gajdán, János Novák, Miklós Sahin-Tóth, Markus M. Lerch, John P. Neoptolemos, Ole H. Petersen, Péter Hegyi
Dátum:2019
ISSN:2044-6055
Megjegyzések:Background: Acute pancreatitis (AP) is an inflammatory condition, which can lead to late consequences. In 20% of patients recurrent AP (RAP) develops and in 7-12.8% chronic pancreatitis (CP) will occur. However, we do not have sufficient information to establish an evidence-based statement to define early CP, or how to prevent its development. Aim: The aim of this study is to understand the influencing factors and to determine, which parameters should be measured or used as a biomarker to detect the early phase of CP. Methods/Design: This is an observational prospective follow-up study of the GOULASH-trial (ISRTCN 63827758) in which i) all severity of pancreatitis are included, ii) patients receive only therapeutic modalities which are accepted by the EBM guideline, iii) whole blood, serum and plasma are stored in our biobank and iv) large amount of variables are collected and kept in our electronic database including anamnestic data, physical examination, laboratory parameters, imaging, therapy and complications, therefore this fully characterized patient-cohort are well suitable for this longitudinal follow up study. Patients' selection: patients enrolled in the GOULASH study will be offered to join to the longitudinal study. The follow-up will be at 1-2-3-4-5 and 6 years after the episode of AP. Anamnestic data will be collected by questionnaires: i) Diet History Questionnaire ii) SF-36 iii) physical activity questionnaire iv) stress questionnaire. Genetic tests will be performed for the genes associated with CP. The exocrine and endocrine pancreatic, liver and kidney functions will be determined by laboratory tests, stool sample analyses, and imaging. Cost-effectiveness will be analyzed to examine the relationship between events of interest and health-related quality of life or to explore subgroup differences. Conclusion: This study will provide information about the risk factors and influencing factors and measurable parameters of CP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
acute pancreatitis
follow-up
chronic pancreatitis
risk factor
Megjelenés:BMJ Open. - 9 : 8 (2019), p. 1-9. -
További szerzők:Erőss Bálint Sarlós Patrícia Hegyi Péter Jr. (belgyógyász) Márta Katalin Pécsi Dániel Vincze Áron Bódis Beáta Nemes Orsolya Faluhelyi Nándor Farkas Orsolya Papp Róbert Kelemen Dezső Szentesi Andrea Hegyi Eszter Papp Mária (1975-) (belgyógyász, gasztroenterológus) Czakó László Izbéki Ferenc Gajdán László Novák János Sahin-Tóth Miklós Lerch, Markus M. Neoptoleomos, Johan P. Petersen, Ole H. Hegyi Péter Jenő (belgyógyász)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
Borító:

9.

001-es BibID:BIBFORM084964
Első szerző:Mosztbacher Dóra
Cím:Hypertriglyceridemia-induced acute pancreatitis : a prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases / Mosztbacher Dóra, Hanák Lilla, Farkas Nelli, Szentesi Andrea, Mikó Alexandra, Bajor Judit, Sarlós Patrícia, Czimmer József, Vincze Áron, Hegyi Péter Jenő, Erőss Bálint, Takács Tamás, Czakó László, Németh Balázs Csaba, Izbéki Ferenc, Halász Adrienn, Gajdán László, Hamvas József, Papp Mária, Földi Ildikó, Fehér Krisztina Eszter, Varga Márta, Csefkó Klára, Török Imola, Farkas Hunor Pál, Mickevicius Artautas, Maldonado Elena Ramirez, Sallinen Ville, Novák János, Ince Ali Tüzün, Galeev Shamil, Bod Barnabás, Sümegi János, Pencik Petr, Dubravcsik Zsolt, Illés Dóra, Gódi Szilárd, Kui Balázs, Márta Katalin, Pécsi Dániel, Varjú Péter, Szakács Zsolt, Darvasi Erika, Párniczky Andrea, Hegyi Péter Jr., Hungarian Pancreatic Study Group
Dátum:2020
ISSN:1424-3903
Megjegyzések:Background. Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates the severity and related complications of AP; however, detailed analyses of large cohorts are inadequate and contradictory. Our aim was to investigate the dose-dependent effect of hypertriglyceridemia on AP. Methods. AP patients over 18 years old who underwent triglyceride measurement within the initial three days were included into our cohort analysis from a prospective international, multicenter AP registry operated by the Hungarian Pancreatic Study Group. Data on 716 AP cases were analyzed. Six groups were created based on the highest triglyceride level (<1.7 mmol/l, 1.7?2.19 mmol/l, 2.2?5.59 mmol/l, 5.6?11.29 mmol/l, 11.3?22.59 mmol/l, ?22.6 mmol/l). Results. Hypertriglyceridemia (?1.7 mmol/l) presented in 30.6% of the patients and was significantly and dose- dependently associated with younger age and male gender. In 7.7% of AP cases, hypertriglyceridemia (?11.3 mmol/l) was considered as a causative etiological factor; however, 43.6% of these cases were associated with other etiologies (alcohol and biliary). Hypertriglyceridemia was significantly and dose-dependently related to obesity and diabetes. The rates of local complications, organ failure and maximum CRP level were significantly and dose- dependently raised by hypertriglyceridemia. Triglyceride above 11.3 mmol/l was linked to a significantly higher incidence of moderately severe AP and longer hospital stay, whereas triglyceride over 22.6 mmol/l was significantly associated with severe AP as well. Conclusion. Hypertriglyceridemia dose-dependently aggravates the severity and related complications of AP. Diagnostic workup for hypertriglyceridemia requires better awareness regardless of the etiology of AP.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
acute pancreatitis
hypertriglyceridemia
etiology
cohort
severity
Megjelenés:Pancreatology. - 20 : 4 (2020), p. 608-616. -
További szerzők:Hanák Lilla Farkas Nelli Szentesi Andrea Mikó Alexandra Bajor Judit Sarlós Patrícia Czimmer József Vincze Áron Hegyi Péter Jenő (belgyógyász) Erőss Bálint Takács Tamás (Szeged) Czakó László Németh Balázs Csaba Izbéki Ferenc Halász Adrienn Gajdán László Hamvas József Papp Mária (1975-) (belgyógyász, gasztroenterológus) Földi Ildikó (1981-) (orvos) Fehér Krisztina Eszter Varga Márta Csefkó Klára Török Imola Farkas Hunor Mickevicius, Artautas Maldonado, Elena Ramirez Sallinen, Ville Novák János Ince, Ali Tüzün Galeev, Shamil Bod Barnabás Sümegi János Pencik, Petr Dubravcsik Zsolt (belgyógyász, gasztroenterológus) Illés Dóra Gódi Szilárd Kui Balázs Márta Katalin Pécsi Dániel Varjú Péter Szakács Zsolt Darvasi Erika Párniczky Andrea (gyermekgyógyász) Hegyi Péter Jr. (belgyógyász) Hungarian Pancreatic Study Group
Pályázati támogatás:K131996
OTKA
FK131864
OTKA
FK124632
OTKA
K120335
OTKA
GINOP 2.3.2-15-2016-00048
GINOP
EFOP-3.6.2-16-2017-00006
EFOP
ÚNKP-19-4
ÚNKP
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

10.

001-es BibID:BIBFORM103703
035-os BibID:(cikkazonosító)2131 (Scopus)85130241509 (WoS)000803398400001
Első szerző:Nagy Rita
Cím:In-Hospital Patient Education Markedly Reduces Alcohol Consumption after Alcohol-Induced Acute Pancreatitis / Nagy Rita, Ocskay Klementina, Váradi Alex, Papp Mária, Vitális Zsuzsanna, Izbéki Ferenc, Boros Eszter, Gajdán László, Szentesi Andrea, Erőss Bálint, Hegyi Péter Jenő, Vincze Áron, Bajor Judit, Sarlos Patricia, Mikó Alexandra, Márta Katalin, Pécsi Dániel, Párniczky Andrea, Hegyi Péter
Dátum:2022
ISSN:2072-6643
Megjegyzések:Although excessive alcohol consumption is by far the most frequent cause of recurrent acute pancreatitis (AP) cases, specific therapy is still not well established to prevent recurrence. Generally, psychological therapy (e.g., brief intervention (BI)) is the cornerstone of cessation programs; however, it is not yet widely used in everyday practice. We conducted a post-hoc analysis of a prospectively collected database. Patients suffering from alcohol-induced AP between 2016 and 2021 received 30 min BI by a physician. Patient-reported alcohol consumption, serum gamma-glutamyl-transferase (GGT) level, and mean corpuscular volume (MCV) of red blood cells were collected on admission and at the 1-month follow-up visit to monitor patients' drinking habits. Ninety-nine patients with alcohol-induced AP were enrolled in the study (mean age: 50 ? 11, 89% male). A significant decrease was detected both in mean GGT value (294 ? 251 U/L vs. 103 ? 113 U/L, p < 0.001) and in MCV level (93.7 ? 5.3 U/L vs. 92.1 ? 5.1 U/L, p < 0.001) in patients with elevated on-admission GGT levels. Notably, 79% of the patients (78/99) reported alcohol abstinence at the 1-month control visit. Brief intervention is an effective tool to reduce alcohol consumption and to prevent recurrent AP. Longitudinal randomized clinical studies are needed to identify the adequate structure and frequency of BIs in alcohol-induced AP
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Nutrients. - 14 : 10 (2022), p. 1-9. -
További szerzők:Ocskay Klementina Váradi Alex (1991-) (biológus) Papp Mária (1975-) (belgyógyász, gasztroenterológus) Vitális Zsuzsanna (1963-) (belgyógyász, gasztroenterológus) Izbéki Ferenc Boros Eszter Gajdán László Szentesi Andrea Erőss Bálint Hegyi Péter Jenő (belgyógyász) Vincze Áron Bajor Judit Sarlós Patrícia Mikó Alexandra Márta Katalin Pécsi Dániel Párniczky Andrea (gyermekgyógyász) Hegyi Péter (pszichológus)
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

11.

001-es BibID:BIBFORM103700
035-os BibID:(scopus)85121564971 (wos)000731322900016 (cikkazonosító)24158
Első szerző:Ocskay Klementina
Cím:Hypoalbuminemia affects one third of acute pancreatitis patients and is independently associated with severity and mortality / Ocskay Klementina, Vinkó Zsófia, Németh Dávid, Szabó László, Bajor Judit, Gódi Szilárd, Sarlós Patrícia, Czakó László, Izbéki Ferenc, Hamvas József, Papp Mária, Varga Márta, Török Imola, Mickevicius Artautas, Sallinen Ville, Maldonado Elena Ramirez, Galeev Shamil, Mikó Alexandra, Erőss Bálint, Imrei Marcell, Hegyi Péter Jenő, Faluhelyi Nándor, Farkas Orsolya, Kanizsai Péter, Miseta Attila, Nagy Tamás, Hágendorn Roland, Márton Zsolt, Szakács Zsolt, Szentesi Andrea, Hegyi Péter, Párniczky Andrea
Dátum:2021
ISSN:2045-2322
Megjegyzések:The incidence and medical costs of acute pancreatitis (AP) are on the rise, and severe cases still have a 30% mortality rate. We aimed to evaluate hypoalbuminemia as a risk factor and the prognostic value of human serum albumin in AP. Data from 2461 patients were extracted from the international, prospective, multicentre AP registry operated by the Hungarian Pancreatic Study Group. Data from patients with albumin measurement in the frst 48 h (n= 1149) and anytime during hospitalization (n= 1272) were analysed. Multivariate binary logistic regression and Receiver Operator Characteristic curve analysis were used. The prevalence of hypoalbuminemia (<35 g/L) was 19% on admission and 35.7% during hospitalization. Hypoalbuminemia dose-dependently increased the risk of severity, mortality, local complications and organ failure and is associated with longer hospital stay. The predictive value of hypoalbuminemia on admission was poor for severity and mortality. Severe hypoalbuminemia (<25 g/L) represented an independent risk factor for severity (OR 48.761; CI 25.276?98.908) and mortality (OR 16.83; CI 8.32?35.13). Albumin loss during AP was strongly associated with severity (p< 0.001) and mortality (p= 0.002). Hypoalbuminemia represents an independent risk factor for severity and mortality in AP, and it shows a dose-dependent relationship with local complications, organ failure and length of stay.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Scientific Reports. - 11 : 1 (2021), p. 1-12. -
További szerzők:Vinkó Zsófia Németh Dávid Szabó László Bajor Judit Gódi Szilárd Sarlós Patrícia Czakó László Izbéki Ferenc Hamvas József Papp Mária (1975-) (belgyógyász, gasztroenterológus) Varga Márta Török Imola Mickevicius, Artautas Sallinen, Ville Maldonado, Elena Ramirez Galeev, Shamil Mikó Alexandra Erőss Bálint Imrei Marcell Hegyi Péter Jenő (belgyógyász) Faluhelyi Nándor Farkas Orsolya Kanizsai Péter Miseta Attila Nagy Tamás Hágendorn Roland Márton Zsolt Szakács Zsolt Szentesi Andrea Hegyi Péter (pszichológus) Párniczky Andrea (gyermekgyógyász)
Pályázati támogatás:EFOP-3.6.2-16-2017-00006
EFOP
GINOP-2.3.2-15-2016-00015
GINOP
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

12.

001-es BibID:BIBFORM079249
Első szerző:Párniczky Andrea (gyermekgyógyász)
Cím:Antibiotic therapy in acute pancreatitis : from global overuse to evidence based recommendations / Andrea Parniczky, Tamas Lantos, Eszter Margit Toth, Zsolt Szakacs, Szilard Godi, Roland Hagendorn, Dora Illes, Balazs Koncz, Katalin Marta, Alexandra Miko, Dora Mosztbacher, Balazs Csaba Nemeth, Daniel Pecsi, Aniko Szabo, Akos Szücs, Peter Varjú, Andrea Szentesi, Erika Darvasi, Balint Eross, Ferenc Izbeki, Laszlo Gajdan, Adrienn Halasz, Aron Vincze, Imre Szabo, Gabriella Par, Judit Bajor, Patrícia Sarlos, Jozsef Czimmer, Jozsef Hamvas, Tamas Takacs, Zoltan Szepes, Laszlo Czako, Marta Varga, Janos Novak, Barnabas Bod, Attila Szepes, Janos Sümegi, Maria Papp, Csaba Gog, Imola Torok, Wei Huang, Qing Xia, Ping Xue, Weiqin Li, Weiwei Chen, Natalia V. Shirinskaya, Vladimir L. Poluektov, Anna V. Shirinskaya, Péter Jenő Hegyi, Marian Batovský, Juan Armando Rodriguez-Oballe, Isabel Miguel Salas, Javier Lopez-Diaz, J. Enrique Dominguez-Munoz, Xavier Molero, Elizabeth Pando, María Lourdes Ruiz-Rebollo, Beatriz Burgueno-Gomez, Yu-Ting Chang, Ming-Chu Chang, Ajay Sud, Danielle Moore, Robert Sutton, Amir Gougol, Georgios I. Papachristou, Yaroslav Mykhailovych Susak, Illia Olehovych Tiuliukin, Antonio Pedro Gomes, Maria Jesus Oliveira, David Joao Aparício, Marcel Tantau, Floreta Kurti, Mila Kovacheva-Slavova, Stephanie-Susanne Stecher, Julia Mayerle, Goran Poropat, Kshaunish Das, Marco Vito Marino, Gabriele Capurso, Ewa Małecka-Panas, Hubert Zatorski, Anita Gasiorowska, Natalia Fabisiak, Piotr Ceranowicz, Beata Kusnierz-Cabala, Joana Rita Carvalho, Samuel Raimundo Fernandes, Jae Hyuck Chang, Eun Kwang Choi, Jimin Han, Sara Bertilsson, Hanaz Jumaa, Gabriel Sandblom, Sabite Kacar, Minas Baltatzis, Aliaksandr Vladimir Varabei, Vizhynis Yeshy, Serge Chooklin, Andriy Kozachenko, Nikolay Veligotsky, Peter Jr. Hegyi, Hungarian Pancreatic Study Group
Dátum:2019
ISSN:1424-3903
Megjegyzések:Background: Unwarranted administration of antibiotics in acute pancreatitis presents a global challenge. The clinical reasoning behind the misuse is poorly understood. Our aim was to investigate current clinical practices and develop recommendations that guide clinicians in prescribing antibiotic treatment in acute pancreatitis. Methods: Four methods were used. 1) Systematic data collection was performed to summarize current evidence; 2) a retrospective questionnaire was developed to understand the current global clinical practice; 3) five years of prospectively collected data were analysed to identify the clinical parameters used by medical teams in the decision making process, and finally; 4) the UpToDate Grading of Rec- ommendations, Assessment, Development and Evaluation (GRADE) system was applied to provide evi- dence based recommendations for healthcare professionals. Results: The systematic literature search revealed no consensus on the start of AB therapy in patients with no bacterial culture test. Retrospective data collection on 9728 patients from 22 countries indicated a wide range (31e82%) of antibiotic use frequency in AP. Analysis of 56 variables from 962 patients showed that clinicians initiate antibiotic therapy based on increased WBC and/or elevated CRP, lipase and amylase levels. The above mentioned four laboratory parameters showed no association with infection in the early phase of acute pancreatitis. Instead, procalcitonin levels proved to be a better biomarker of early infection. Patients with suspected infection because of fever had no benefit from antibiotic therapy. Conclusions: The authors formulated four consensus statements to urge reduction of unjustified anti- biotic treatment in acute pancreatitis and to use procalcitonin rather than WBC or CRP as biomarkers to guide decision-making.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Acute pancreatitis
Antibiotic
Guideline
Recommendation
Infection
Megjelenés:Pancreatology. - 19 : 4 (2019), p. 488-499. -
További szerzők:Lantos Tamás Tóth Eszter Margit Szakács Zsolt Gódi Szilárd Hágendorn Roland Illés Dóra Koncz Balázs Márta Katalin Mikó Alexandra Mosztbacher Dóra Németh Balázs Csaba Pécsi Dániel Szabó Anikó Szűcs Ákos (sebész) Varjú Péter Szentesi Andrea Darvasi Erika Erőss Bálint Izbéki Ferenc Gajdán László Halász Adrienn Vincze Áron Szabó Imre (1952-) (orvos) Pár Gabriella Bajor Judit Sarlós Patrícia Czimmer József Hamvas József Takács Tamás (Szeged) Szepes Zoltán Czakó László Varga Márta Novák János Bod Barnabás Szepes Attila Sümegi János Papp Mária (1975-) (belgyógyász, gasztroenterológus) Góg Csaba Török Imola Huang, Wei Xia, Qing Xue, Ping Li, Weiqin Chen, Weiwei Shirinskaya, Natalia V. Poluektov, Vladimir L. Shirinskaya, Anna V. Hegyi Péter Jenő (belgyógyász) Bátovský, Marian Rodriguez-Oballe, Juan Armando Salas, Isabel Miguel Lopez-Diaz, Javier Dominguez-Munoz, J. Enrique Molero, Xavier Pando, Elizabeth Ruiz-Rebollo, María Lourdes Burgueño-Gómez, Beatriz Chang, Yu-Ting Chang, Ming-Chu Sud, Ajay Moore, Danielle Sutton, Robert Gougol, Amir Papachristou, Georgios I. Susak, Yaroslav Mykhailovych Tiuliukin, Illia Olehovych Gomes, António Pedro Oliveira, Maria Jesus Aparício, David João Tantau, Marcel Kurti, Floreta Kovacheva-Slavova, Mila Stecher, Stephanie-Susanne Mayerle, Julia Poropat, Goran Das, Kshaunish Marino, Marco Vito Capurso, Gabriele Małecka-Panas, Ewa Zatorski, Hubert Gasiorowska, Anita Fabisiak, Natalia Ceranowicz, Piotr Kuśnierz-Cabala, Beata Carvalho, Joana Rita Fernandes, Samuel Raimundo Chang, Jae Hyuck Choi, Eun Kwang Han, Jimin Bertilsson, Sara Jumaa, Hanaz Sandblom, Gabriel Kacar, Sabite Baltatzis, Minas Varabei, Aliaksandr Vladimir Yeshy, Vizhynis Chooklin, Serge Kozachenko, Andriy Veligotsky, Nikolay Hegyi Péter Jr. (belgyógyász) Hungarian Pancreatic Study Group
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