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001-es BibID:	BIBFORM114632
035-os BibID:	(cikkazonosító)2954 (scopus)85172226742 (wos)001073257100001
Első szerző:	Janka Tamás
Cím:	The Value of Neutrophil-to-Lymphocyte Ratio to Identify Bacterial Infection and Predict Short-Term Mortality in Patients with Acutely Decompensated Cirrhosis / Tamás Janka, Dávid Tornai, Mária Papp, Zsuzsanna Vitális
Dátum:	2023
ISSN:	2075-4418
Megjegyzések:	Liver cirrhosis patients are highly susceptible to infections, affecting survival, but current param-eters for detecting infection are not reliable enough in this population. We investigated ability of white blood cell (WBC), ?WBC, neutrophil and ?neutrophil count, neutrophil-to-lymphocyte (NLR) and ?NLR ratio, CRP, and PCT to identify infection and predict short-term mortality in liver cir-rhosis patients. We recruited 233 patients with liver cirrhosis hospitalized with acute decompen-sation (AD) who had an outpatient visit within 1 month (baseline laboratory data) and followed them for 90 days. Difference between laboratory values at baseline and the AD episode was defined as delta (?) values of the parameters. Delta values did not increase the diagnostic and predictive ability of investigated parameters. CRP was found to be the best diagnostic marker for infection in patients with cirrhosis. However, NLR seems to be superior for short-term mortality prediction, better than WBC. Distinguishing inflammations of different origin is a remaining clinical challenge in acutely decompensated cirrhosis. Based on our results NLR might be more suitable for predicting short-term mortality in patients with AD than WBC count currently included in CLIF-C AD score.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Diagnostics. - 13 : 18 (2023), p. 1-14. -
További szerzők:	Tornai Dávid (1989-) (hepatológia, biomarker kutatás) Papp Mária (1975-) (belgyógyász, gasztroenterológus) Vitális Zsuzsanna (1963-) (belgyógyász, gasztroenterológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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